معرفی
Sarah Palmer is a Professor at the University of Sydney's School of Medicine and Co-Director of the Centre for Virus Research at The Westmead Institute for Medical Research. She holds a PhD in Medical Sciences (Virology) from Karolinska Institutet and completed post-doctoral studies at Stanford University Medical School. Prior to her current role (2013-present), she was a Senior Researcher at the Swedish Institute for Communicable Disease Control and Karolinska Institutet (2008-2012), and headed the Virology Core Facility at the NIH's HIV Drug Resistance Program (2000-2008).
Her research focuses on HIV pathogenesis, viral reservoirs, and eradication strategies. Key areas include:
- Molecular mechanisms of HIV persistence during antiretroviral therapy
- Characterization of latent reservoirs across tissues and immune cells
- Impact of co-infections (HBV, TB) on HIV reservoirs
- Development of assays for intact proviral DNA quantification
- Immune checkpoint markers (PD-1/CTLA-4) in viral persistence
Her recent publications (2014-2024) demonstrate consistent focus on HIV reservoir dynamics, with emerging themes in:
- Single-cell analysis of viral reservoirs
- Impact of immune activation on viral persistence
- Novel latency-reversal strategies (HDAC inhibitors)
- Co-infection interactions (HIV-HBV/TB)
- T-cell based eradication approaches
She leads multiple NIH-funded projects including:
- DARE: Delaney AIDS Research Enterprise (HIV cure initiative)
- Longitudinal assessment of immune activation/HIV persistence
- Characterization of latent HIV-1 reservoirs
- Impact of HBV coinfection on HIV reservoirs
As Co-Director of the Centre for Virus Research, she collaborates internationally on HIV eradication strategies and mentors researchers in virology and immunology.
