معرفی
Ping-Xia Zhang, MD, PhD, is an Associate Research Scientist in the Department of Laboratory Medicine at Yale School of Medicine. She holds an MD from Henan Medical University (1983), a PhD in Immunology from Beijing Medical University (1995), and completed postdoctoral training at Yale University School of Medicine (1999). Dr. Zhang is affiliated with the Bruscia Lab, conducting research in pulmonary inflammation mechanisms.
Her research focuses on molecular pathways underlying inflammatory responses in cystic fibrosis, including monocyte/macrophage adaptation, hematopoietic stem cell regulation, and signaling pathways like AKT/microRNA-199a-5p/CAV1. Key interests include lung microenvironment interactions, protein trafficking defects, and therapeutic modulation of hyperinflammation.
Dr. Zhang's publications reveal consistent focus on cystic fibrosis pathogenesis, with recent work exploring ezrin-mediated monocyte adaptation in inflamed lungs and CDK9/RUNX1 mechanisms in hematopoietic differentiation. Her foundational studies established macrophage contributions to CFTR-related inflammation.
