معرفی
Leslie B. Poole, PhD is a Professor and Co-Director of the Center for Redox Biology & Medicine at Wake Forest School of Medicine. Her NIH-funded research program investigates redox regulation mechanisms with implications for cancer and disease.
Research Focus:
- Peroxiredoxin catalysis and regulation
- Protein sulfenylation detection methods
- Redox signaling in cancer and inflammation
- Thiol-based redox switches
Publications: Over 100 publications (1998-2023) in redox biology, including studies of peroxiredoxin mechanisms, cysteine oxidation, redox signaling pathways, and diagnostic probes for protein sulfenylation.
Funding: Multiple NIH R01 grants including GM050389 (1993-2016), GM119227 (2016-2021), and GM135179 (2020-2025), focusing on redox proteins and signaling pathways.
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