معرفی
Professor Keith Channon is the Field Marshal Earl Alexander Professor of Cardiovascular Medicine and Professorial Fellow at the University of Oxford's Department of Cardiovascular Medicine. He serves as Head of Department and Associate Head of the Medical Sciences Division (Clinical Research).
- Field Marshal Earl Alexander Professor of Cardiovascular Medicine
- Professorial Fellow
- Head of Department of Cardiovascular Medicine
- Associate Head of Medical Sciences Division (Clinical Research)
His research focuses on nitric oxide (NO) and redox signalling in cardiovascular disease, particularly how NO dysregulation drives endothelial dysfunction and vascular pathologies like atherosclerosis. He investigates the role of tetrahydrobiopterin in modulating NO synthase activity and explores transgenic models to manipulate this pathway.
Key research themes include:
- Endothelial dysfunction in diabetes and coronary artery disease
- NO synthase regulation by tetrahydrobiopterin
- Reactive oxygen species (ROS) interactions with NO
- Clinical trials targeting NO pathway restoration
- Monocyte/macrophage dynamics in atherosclerosis
- Mitochondrial redox balance
His work bridges clinical studies and experimental models, with recent publications highlighting applications in machine learning for medical imaging, STEMI intervention, and photon-counting CT angiography. He holds fellowships from the Academy of Medical Sciences and Royal College of Physicians.
