
معرفی
Keith Blackwell is a Senior Investigator and Section Head at Joslin Diabetes Center, with dual appointments as Professor of Genetics at Harvard Medical School. His research focuses on aging mechanisms using C. elegans models.
- B.S. in Chemistry, Duke University (1978)
- M.D., Columbia University (1987)
- Ph.D. in Microbiology, Columbia University (1988)
Blackwell's work investigates how growth regulatory pathways like insulin/IGF-1 and TOR signaling influence stress defenses, aging, and stem cell function. His lab pioneered studies on SKN-1/NRF2 transcription factor networks in longevity and stress response.
Recent publications highlight his contributions to understanding mitochondrial stress signaling, redox regulation, and nutrient-sensing networks in aging. Key findings include the role of AMPK in exercise-mediated longevity and hydrogen sulfide in stress resistance.
- Harvard Medical School - Department of Genetics
- Joslin Diabetes Center - Section on Developmental and Stem Cell Biology
His lab actively explores C. elegans as a platform for aging research, with implications for diabetes, cancer, and age-related diseases.
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