معرفی
Delphine Larsen Martin is the Team Leader of the Microbiota & Immune Trajectories research group at Sorbonne University. Her work focuses on understanding immune aging (immunosenescence) and its impact on health outcomes in older adults, particularly in contexts of chronic infections (e.g., HIV, CMV, SARS-CoV-2) and acute stress scenarios like trauma or sepsis. She leads a multidisciplinary team investigating cellular and molecular mechanisms underlying immune dysfunction in aging populations.
Her research is structured around three core axes: 1) Characterizing immunosenescence markers and their clinical implications, 2) Exploring stress-immune interactions in acute clinical settings, and 3) Developing translational strategies targeting hematopoietic stem cells and regenerative pathways. Collaborations include international networks studying biomarker validation, clinical trials, and novel therapeutic targets for age-related immune decline.
Key publications address herpesvirus impacts on elderly immunity, HIV-associated immunological aging, and cytokine profiles predictive of severe COVID-19 outcomes. Team members include PhD candidates and clinical researchers from Sorbonne University and affiliated hospitals like Pitié-Salpêtrière. Current projects aim to identify predictive biomarkers and improve clinical management of vulnerable geriatric populations.
