جست‌وجوی استاد و پژوهشگر

• Synthetic Biology
• Biopharmaceutical Processing
• Neurodegeneration and Ageing
• +۷ مورد دیگر

Professor Karen Polizzi is a Professor of Biotechnology in the Department of Chemical Engineering at Imperial College London, affiliated with multiple research centers including the CDT in Chemical Biology, Centre for Synthetic Biology, and Future Vaccine Manufacturing Research Hub. Her work focuses on developing synthetic biology tools and biosensors to monitor and correct cellular behavior, with applications in biopharmaceutical processing and neurodegenerative disease research. Her research integrates genetically-encoded biosensors and synthetic circuits to enable self-correcting organisms, addressing challenges in vaccine production, antibody engineering, and cellular diagnostics. Key affiliations include the Leverhulme Centre for Cellular Bionics and UKRI AI for Engineering Biology Consortium. Polizzi’s expertise spans protein engineering, metabolic modeling, and cell-free systems, with a strong emphasis on translating synthetic biology into industrial and medical applications. Her work bridges fundamental biological understanding with practical bioprocessing innovations, particularly in optimizing glycosylation pathways and improving bioreactor monitoring through advanced sensing technologies. Her interdisciplinary approach combines computational modeling with experimental validation, addressing complex systems like antibody production in Chinese hamster ovary (CHO) cells and mRNA integrity assessment for therapeutic applications. She leads teams developing novel biosensors for real-time cellular monitoring and has pioneered tools like the 'Bioorthogonal Precision Tool' for enzyme engineering.

• Process Systems Engineering
• Energy Systems Optimization
• Low-Carbon Technologies
• +۴ مورد دیگر

Professor Nilay Shah is a Professor of Process Systems Engineering at Imperial College London's Department of Chemical Engineering within the Faculty of Engineering. He holds affiliations with the Sargent Centre for Process Systems Engineering and multiple interdisciplinary initiatives including the Agri Futures Lab, Energy Futures Lab, and Future Vaccine Manufacturing Research Hub. His professional experience includes serving as Head of the Department of Chemical Engineering (2016-2021) and Director of the Centre for Process Systems Engineering (2009-2016). Shah's research focuses on energy systems optimization, low-carbon technologies, supply chain design, and biopharmaceutical manufacturing. Key areas include bioenergy systems, urban energy solutions, and industrial decarbonisation. He has pioneered methods for integrating sustainability into supply chains and pharmaceutical processes. His work spans over 30 years at Imperial College, where he has also received awards such as the Junior Moulton Medal (1996) and Teaching Excellence Award (1995). His current projects address global challenges in green hydrogen infrastructure, vaccine manufacturing resilience, and carbon capture technologies.

Ender Konukogluمشاهده پروفایل

دانشیار

• Biomedical Imaging
• Computer Vision
• Medical Image Segmentation
• +۳ مورد دیگر

Prof. Ender Konukoglu is an Associate Professor at the Department of Information Technology and Electrical Engineering at ETH Zürich, leading the Computer Vision Laboratory. He holds a PhD from the University of Nice Sophia Antipolis (2009), following B.S. and M.S. degrees from Bogazici University. His postdoctoral work included roles at Microsoft Research (2009–2012) and Harvard Medical School (2012–2016), where he contributed to computational neuroimaging and radiology. His research focuses on biomedical image computing, with emphasis on medical image segmentation, computer vision in surgery, and deep learning applications in healthcare. Key contributions include real-time anatomical guidance systems, multimodal image analysis, and predictive models for clinical outcomes. His work spans 3D reconstruction, radiomics, and domain adaptation in medical imaging. His research interests include leveraging computer vision and deep learning for medical diagnostics, surgical assistance, and quantitative imaging. Notable projects include the AENEAS initiative for endoscopic neurosurgery guidance and the development of benchmark datasets for cross-modality harmonization. He has published extensively on topics like camouflaged object segmentation, Gaussian splatting for scene understanding, and predictive analytics for cardiovascular procedures. Prof. Konukoglu’s awards and recognitions are not explicitly listed in the provided text. His team’s work on synthetic CT generation for radiotherapy and the Tera-MIND brain simulation project highlights his interdisciplinary impact. Ongoing efforts focus on robust medical image segmentation, domain generalization, and real-time surgical navigation systems.

• RNA Biology
• Pre-mRNA Splicing
• Genomics
• +۵ مورد دیگر

Jeffrey Pleiss is an Associate Professor in the Department of Molecular Biology and Genetics at Cornell University, part of the College of Agriculture and Life Sciences. His research focuses on RNA biology, particularly mechanisms of pre-mRNA splicing and gene expression regulation in eukaryotes. He employs biochemical, biophysical, and high-throughput genomic techniques, leveraging yeast models such as Schizosaccharomyces pombe . Dr. Pleiss holds a B.A. in Chemistry from Northwestern University, a Ph.D. from the University of Colorado Boulder, and completed postdoctoral training at UCSF under Christine Guthrie. His work is funded by the NIH and American Cancer Society. He teaches BIOG 2990: Introduction to Research Methods in Biology and maintains an active lab focused on RNA processing pathways. His recent publications explore splicing dynamics, novel factors, and methodological advancements in RNA sequencing. Research interests include: RNA splicing regulation, alternative splicing mechanisms, genomic tools for transcript analysis, and the interplay between transcription and splicing. Key themes in his work involve using yeast systems to uncover conserved principles applicable to human biology.

Tudorita Tumbarمشاهده پروفایل

استاد

• Stem Cell Biology
• Epithelial Stem Cells
• Hair Follicle Development
• +۵ مورد دیگر

Tudorita Tumbar is a Professor in the Department of Molecular Biology and Genetics at Cornell University, within the College of Agriculture and Life Sciences (CALS). Her research focuses on molecular mechanisms governing stem cell behavior in skin, particularly hair follicle and epidermal stem cells. She employs genetic and genomic tools to explore how intrinsic factors (e.g., transcriptional regulation, epigenetics) and extrinsic signals (e.g., niche interactions) regulate stem cell fate in development and disease. Education: PhD in Cell Biology (University of Illinois, 2000), BS/MS in Biochemistry (University of Bucharest, 1993). Teaching: Courses include Introductory Cell and Developmental Biology and Stem Cells and Regeneration. Awards: Humboldt Research Award (2020). Labs/Teams: Tumbar Lab of Tissue Stem Cell Biology, collaborating with institutions like Cologne University. Grants: NIH-funded projects on skin stem cell niches and regeneration. Research Interests: Hair follicle stem cells, epigenetic regulation, skin wound healing, vascular-niche interactions, and mechanisms underlying tissue homeostasis. Her work bridges basic biology with translational applications in regenerative medicine and cancer research. Lab Activities: Training undergraduate and graduate students, postdocs, and managing NIH-funded projects. Recent studies include vascular signaling in stem cell activation (EMBO J, 2023) and niche heterogeneity in skin protection (EMBO J, 2022).

• Nanotechnology
• Biomedical Engineering
• Drug Delivery Systems
• +۱ مورد دیگر

Professor Ken Tye Yong is Associate Dean (External Engagement) for the Faculty of Engineering and Professor in the School of Biomedical Engineering at the University of Sydney. His research spans nanotechnology, biomedical imaging, drug delivery systems, and biophotonics, with emphasis on nanoparticle-based therapies and diagnostic platforms. He leads initiatives in external engagement through the Warren Centre and oversees research on nanomaterial applications in healthcare. Current projects include neuromorphic imaging cytometry, SERS-based cellular monitoring, and biomimetic tissue scaffolds. Publications demonstrate consistent focus on interdisciplinary approaches combining nanomaterials engineering with clinical applications. Research outputs frequently involve microfluidic systems, targeted drug delivery, and advanced imaging techniques. Recent work emphasizes neuroprotective therapies, wearable biosensors, and mRNA vaccine delivery platforms.

Brian Morrisمشاهده پروفایل

استاد

• Schizophrenia
• Neuronal Plasticity
• Protein Signaling
• +۴ مورد دیگر

Professor Brian Morris is a faculty member at the University of Glasgow, serving as Professor of Molecular Neurobiology within the School of Psychology & Neuroscience. His research focuses on schizophrenia mechanisms, neuronal plasticity, and neurodegenerative diseases, with a particular emphasis on protein signaling, mRNA translation, and gene transcription. He co-founded YRING and co-directs the Psychiatric Research Institute of Neuroscience (PsyRING) in collaboration with other institutions. Morris has held a Wellcome Trust University Award and contributed to over 60 publications. His research integrates genetic, genomic, and molecular approaches to understand psychiatric diseases and synaptic plasticity. Key projects include studying the role of RhoB in synaptic plasticity, MAP kinase pathways in immune responses, and the impact of maternal immune activation on schizophrenia risk. Morris supervises postgraduate students and has secured grants from bodies like the Biotechnology and Biological Sciences Research Council. Notable achievements include advancing rodent models for schizophrenia drug discovery and identifying genetic risk factors like MAP2K7. His work bridges translational research, linking preclinical findings to clinical applications in neuropsychiatric disorders.

Ian Sudberyمشاهده پروفایل

مدرس ارشد

• Gene Regulation
• MicroRNAs
• Chromatin Structure
• +۴ مورد دیگر

Dr. Ian Sudbery is a Senior Lecturer in Bioinformatics at the School of Biosciences, University of Sheffield, a position he has held since 2022. Previously, he served as a Lecturer in Bioinformatics at the same institution from 2014 to 2022. His academic journey includes roles such as a CGAT Fellow at the MRC Functional Genomics Unit, University of Oxford (2011–2014), and Postdoctoral Research Fellowships at Harvard Medical School and the Wellcome Trust Sanger Institute. Dr. Sudbery earned his PhD in Functional Genomics from the Wellcome Trust Sanger Institute and the University of Cambridge (2003–2007). He has also held postdoctoral positions at Harvard Medical School and the Wellcome Trust Sanger Institute, focusing on systems biology and functional genomics. His research interests revolve around understanding gene regulation and its malfunction in diseases. Key areas include the role of microRNAs in regulatory networks, chromatin structure in disease contexts, and computational genomics methodologies. Specific topics include how microRNAs threshold gene expression, the interplay between enhancers and promoters in chromatin structure, and the application of computational tools to study these processes. His work spans topics such as miRNA function, chromatin-based regulatory rewiring in cancer, and the development of computational tools for genomic analysis, as evidenced by his publications in Nature , Nature Communications , and others. Collaborations with institutions like Imperial University explore chromatin structure's role in disease. His contributions include widely used tools like Alevin and UMI-tools for RNA-seq data analysis.

• Structural Biology
• Protein Biochemistry
• DNA Recombination
• +۳ مورد دیگر

Dr. John Rafferty is a Reader in Structural Biology at the University of Sheffield's School of Biosciences. He has held this position since 2005, following roles as a Royal Society Olga Kennard Fellow (1999–2004) and BBSRC David Phillips Research Fellow (1996–1999). His research focuses on structural biology, particularly studying enzymes, DNA recombination proteins, and bacterial virulence factors using X-ray crystallography and biophysical techniques. Key career milestones include structural analyses of Holliday junction resolvases (RuvA, RusA), phage helicase loaders, and bacterial transport proteins. His work has advanced understanding of DNA repair mechanisms and enzyme-ligand interactions in pathogenic bacteria like Campylobacter jejuni and Bacteroidetes species. Teaching responsibilities include coordinating the Level 1 Biochemistry module (MBB161) and contributing to advanced courses in molecular biosciences. He serves as an external examiner at the University of Birmingham. Education: PhD in Biophysics (Leeds University, 1986–1990) Labs/Teams: Structural Biology Group at Sheffield, collaborating with researchers like Sedelnikova SE and Rice DW on DNA recombination and enzyme structure. Grants: Funded by BBSRC, Royal Society, and Wellcome Trust for projects on bacterial pathogenesis and protein engineering.

• Biophysics
• Molecular Biology
• Microscopy
• +۱ مورد دیگر

Ulrich Kubitscheck is a Professor at the University of Bonn's Clausius Institute for Physical and Theoretical Chemistry. His research focuses on molecular dynamics in biological systems using advanced microscopy techniques. His group develops and applies cutting-edge light microscopy methods including confocal scanning, single-molecule microscopy, and light sheet fluorescence microscopy. Current research emphasizes nucleocytoplasmic transport, neuronal connectomics, and antibiotic mechanisms at molecular scales. Kubitscheck's innovative microscopy techniques enable real-time observation of molecular kinetics in supramolecular complexes, advancing understanding of cellular processes and antibiotic function.

Michael Wormingtonمشاهده پروفایل

دانشیار

• Molecular Biology
• Developmental Biology
• Gene Regulation
• +۳ مورد دیگر

Michael Wormington is an Associate Professor of Biology and Faculty Fellow at the Jefferson Scholars Foundation, University of Virginia. His primary affiliation is with the Department of Biology within the College of Arts & Sciences. He can be contacted at 434 982-5803 or via email at ww2t@virginia.edu , with an office at 417 Gilmer and a lab contact at 434 982-5804. Education includes a B.A. (1975) and Ph.D. (1979) from the University of Kansas, followed by postdoctoral research at the Carnegie Institute (1979–1982). Research focuses on microRNA (miRNA) regulation during Xenopus oogenesis and embryogenesis. Key areas include miRNA biogenesis, RISC complex function, and the maternal-to-zygotic transition. Dr. Wormington uses molecular, cellular, and biochemical approaches to study how miRNAs control gene expression during developmental processes, particularly the roles of Ago2, DGCR8, Dicer, and Drosha proteins. Current investigations explore how progesterone-induced meiotic maturation activates miRNA processing and how RISC participates in the degradation of maternal mRNAs during embryogenesis. Though no specific awards are listed, his work contributes to foundational understanding of epigenetic regulation in developmental biology. No advising or grant details are provided in the text, but his laboratory research emphasizes the mechanistic basis of cellular specialization during early embryonic development.

• RNA interference
• Gene regulation
• Plant biotechnology
• +۴ مورد دیگر

Dr Felipe Fenselau de Felippes holds the position of Senior Research Associate within QUT's School of Biology & Environmental Science, part of the Faculty of Science. He completed his PhD at the Max Planck Institute for Developmental Biology (Germany) and postdoctoral research at ETH Zurich (Switzerland). His career has focused on RNA interference mechanisms in plants, particularly their roles in development, viral defense, and abiotic stress responses. Research interests include gene regulation via small RNAs, plant biotechnology applications, and genomic approaches to studying plant responses. He teaches BVB317 - Principles of Genomics and Biotechnology. Key contributions include work on transgene expression optimization using terminator elements and multi-omic analysis of Nicotiana benthamiana. Publications span plant stress responses, viral resistance mechanisms, and foundational studies in RNA silencing pathways. His work has been published in New Phytologist , Nature Plants , and Plant Journal . Current research emphasizes drought response strategies and translational plant biotechnology solutions.

• Biosensor Development
• Protein Engineering
• Electrochemical Sensors
• +۳ مورد دیگر

Dr. Zhong Guo is a Researcher at the School of Biology & Environmental Science, Faculty of Science, Queensland University of Technology (QUT). His work focuses on developing biosensors through protein engineering, with applications in diagnostics and clinical samples. He holds a PhD and collaborates extensively with researchers like Dr. Konstantin Alexandrov and Dr. Evgeny Katz on bioelectronic systems and synthetic biology projects. His research interests include biosensor design, electrochemical and fluorometric sensing technologies, and synthetic allostery. Key contributions include the creation of lanthanide-controlled protein switches and mRNA display pipelines for biosensor construction. His work bridges molecular biology, biochemistry, and engineering to advance point-of-care diagnostics and biotechnological tools. Publications highlight innovations in protein logic gates, chimeric enzymes, and magnetic signal-activated systems. These contributions underscore his role in integrating biological systems with electronic interfaces for biomedical applications.

Souvarish Sarkarمشاهده پروفایل

استادیار

• Neurodegenerative Diseases
• Neuroinflammation
• Gene-Environment Interactions
• +۶ مورد دیگر

Souvarish Sarkar, Ph.D., is an Assistant Professor in the Department of Environmental Medicine and Neuroscience (joint appointment) at the University of Rochester School of Medicine and Dentistry. His research focuses on understanding gene-environment interactions in neurodegenerative diseases, particularly Parkinson's disease (PD), using Drosophila genetics, rodent models, and cell culture systems. He completed his Ph.D. in Molecular, Cellular, and Developmental Biology at Iowa State University and postdoctoral training at Harvard Medical School with Dr. Mel Feany. Education: B.Tech. in Biotechnology, Heritage Institute of Technology, India (2013) Ph.D. in Molecular Toxicology, Iowa State University (2018) Research Interests: Dr. Sarkar's work investigates how environmental toxicants (e.g., pesticides, metals) interact with genetic factors to drive neuroinflammation and neurodegeneration. Key areas include: Mechanisms of α-synuclein pathology and prion-like propagation Role of microglial ion channels and exosome signaling in PD Development of multiplex models to study gene-environment interactions Impact of mitochondrial dysfunction in neurotoxicity Awards: NIH K99/R00 Career Transition Grant (2022) Young Investigator Award (2025) Multiple recognitions for research excellence in neurotoxicology (2017–2023) Lab Activities: His lab integrates molecular biology, proteomics, and in vivo models to study: Environmental manganese's role in PD pathogenesis Gene-environment interaction networks in neurodegeneration Development of novel therapeutic strategies targeting neuroinflammatory pathways Collaborations: Active partnerships with the Environmental Health Sciences Center and Del Monte Institute for Neuroscience at URMC.

Hannah Burgessمشاهده پروفایل

مدرس ارشد

• Virology
• RNA Biology
• Host-Pathogen Interactions
• +۳ مورد دیگر

Dr. Hannah Burgess is a Visiting Senior Lecturer at the School of Biosciences , University of Surrey, specializing in the Section of Virology . Her research focuses on the intersection of mRNA metabolism and virus infection, particularly exploring how viral and host factors influence mRNA processes during infections like HCMV and coronaviruses. She holds affiliations with the Microbiology Society and Biochemical Society . Education: BSc in Genetics, University of Nottingham PhD in Human Genetics at MRC Human Genetics Unit (Edinburgh), supervised by Nicola Gray Research Highlights: Investigates host RNA decay pathways in HCMV infection and dsRNA regulation in herpesviruses Explores viral manipulation of cellular translation machinery under stress conditions Collaborates with Angus Wilson at NYU School of Medicine Publications: Showcase interdisciplinary work on viral RNA regulation, antiviral strategies, and host-pathogen interactions Includes studies on SARS-CoV-2, HCMV, vaccinia virus, and coronaviruses Labs/Teams: Active in the Virology Section at Surrey, focusing on translational research in viral RNA biology.