Ian Sudbery

Dr. Ian Sudbery is a Senior Lecturer in Bioinformatics at the School of Biosciences, University of Sheffield, a position he has held since 2022. Previously, he served as a Lecturer in Bioinformatics at the same institution from 2014 to 2022. His academic journey includes roles such as a CGAT Fellow at the MRC Functional Genomics Unit, University of Oxford (2011–2014), and Postdoctoral Research Fellowships at Harvard Medical School and the Wellcome Trust Sanger Institute.

Dr. Sudbery earned his PhD in Functional Genomics from the Wellcome Trust Sanger Institute and the University of Cambridge (2003–2007). He has also held postdoctoral positions at Harvard Medical School and the Wellcome Trust Sanger Institute, focusing on systems biology and functional genomics.

His research interests revolve around understanding gene regulation and its malfunction in diseases. Key areas include the role of microRNAs in regulatory networks, chromatin structure in disease contexts, and computational genomics methodologies. Specific topics include how microRNAs threshold gene expression, the interplay between enhancers and promoters in chromatin structure, and the application of computational tools to study these processes.

His work spans topics such as miRNA function, chromatin-based regulatory rewiring in cancer, and the development of computational tools for genomic analysis, as evidenced by his publications in Nature, Nature Communications, and others. Collaborations with institutions like Imperial University explore chromatin structure's role in disease. His contributions include widely used tools like Alevin and UMI-tools for RNA-seq data analysis.