جست‌وجوی استاد و پژوهشگر

• Developmental Biology
• Cancer Biology
• Stem Cell Biology
• +۴ مورد دیگر

Ann F. Ramsdell is an Associate Professor in the Department of Cell Biology and Anatomy at the University of South Carolina School of Medicine Columbia. She also holds ancillary appointments in Women's and Gender Studies and the Department of Regenerative Medicine and Cell Biology, and is a member of the Hollings Cancer Center. Her research explores how positional information informs organ development and disease susceptibility, with particular emphasis on left-right asymmetry in mammary gland biology and breast cancer. Education: 1991: B.S. in Biology (Minor: Philosophy) from the College of Charleston 1996: Ph.D. in Cell Biology and Anatomy from the Medical University of South Carolina Ramsdell's work bridges developmental biology, cancer biology, and epigenetics, focusing on molecular and cellular laterality in mammalian systems. Her lab pioneered the discovery that left-right differences in mammary glands predict patient survival outcomes, suggesting tumor laterality remains an underexplored factor in oncology. Using mouse models, she investigates epigenetic regulation of stem cells during mammary development and oncogenesis. Her publications since 2004 highlight cross-disciplinary contributions to understanding left-right axis determination, cardiac development, and neoplastic transformation. Recent studies employ fractal analysis and molecular profiling to detect early cancer-related changes.

• Gastrointestinal Carcinogenesis
• Epigenetics
• Genetics
• +۳ مورد دیگر

Dr. Hassan Ashktorab is a Professor in the Department of Medicine at Howard University's College of Medicine. He holds multiple roles, including membership in the Howard University Cancer Center's gastrointestinal working group and executive membership in the Howard University Cancer Center. He is also an Adjunct Professor in the Department of Genetics and Human Genetics and former Chair of the College of Medicine Research Committee. His expertise spans gastrointestinal carcinogenesis, epigenetics, microbiome studies, and colorectal cancer epidemiology. Dr. Ashktorab has published over 175 peer-reviewed articles and led NIH-funded grants (RO3, RO1, DOD). He received the HU-COM Outstanding Researcher Award (2011) and serves on NIH study sections since 2005. His lab focuses on saffron's role in IBD treatment and microbiome-cancer interactions. Education: B.S. in Medical Technology, Shiraz University (1984) M.S. in Molecular Biology, Utah State University (1986) Ph.D. in Molecular Biology, Utah State University (1988) Postdoctoral Fellowship in Cancer Biology, University of Florida (1988-1992) Research Interests: Dr. Ashktorab's work investigates the interplay between epigenetics, microbiome, and gastrointestinal cancers, particularly colorectal cancer. His lab explores how gut microbiota influence carcinogenesis and the therapeutic potential of saffron in IBD. Recent studies include clinical trials evaluating saffron's efficacy in ulcerative colitis, leveraging its anti-inflammatory properties via Ahr/Nrf-2 pathways. Awards & Grants: HU-COM Outstanding Researcher Award (2011) NIH Grants (RO3, RO1) DOD Grants Labs & Collaborations: His research group operates within the Howard University Cancer Center and collaborates on projects involving the Microarray Facility. Ongoing studies include genomic profiling of intestinal metaplasia and molecular phenotyping of gastric cancer.

Jennifer McDonoughمشاهده پروفایل

دانشیار

• Neurodegeneration
• Multiple Sclerosis
• Methionine Metabolism
• +۲ مورد دیگر

Dr. Jennifer McDonough is an Associate Professor in Biological Sciences at Kent State University. Her research focuses on identifying neuroprotective therapies for multiple sclerosis (MS), with specific emphasis on methionine metabolism, histone methylation, mitochondrial dysfunction, and neuronal hemoglobin expression. Additional research explores epigenetic mechanisms in opioid addiction and neurodevelopmental disorders. Her laboratory investigates how disruptions in metabolic pathways contribute to neurodegeneration, using models like cuprizone-induced demyelination and Canavan disease. Recent articles demonstrate significant work in epigenetic regulation, astrocyte pathology, 3D neural tissue engineering, and therapeutic interventions targeting metabolic pathways. Publication analysis reveals strong emphasis on glial biology, mitochondrial function, and translational neurotherapeutics. Dr. McDonough received her Ph.D. from Case Western Reserve University and directs research at Kent State's Advanced Materials and Liquid Crystal Institute.

Qing-Song Liuمشاهده پروفایل

استاد

• Neuropharmacology
• Drug Addiction
• Endocannabinoid Signaling
• +۶ مورد دیگر

Qing-Song Liu is a Professor at the Medical College of Wisconsin , Department of Pharmacology and Toxicology. His research focuses on the neuropharmacological mechanisms of drug addiction, anxiety, and depression, particularly the role of the mesolimbic dopamine system and endocannabinoid signaling in neural circuit adaptations. Research Interests include: Cellular and molecular changes in brain reward circuits after chronic drug use Endocannabinoid regulation of stress-buffering effects in anxiety/depression Synaptic plasticity in ventral tegmental area (VTA) and nucleus accumbens (NAc) Translational studies using electrophysiology, optogenetics, and behavioral paradigms Publication Trends (2016–2021) span neuropharmacology , addiction biology , and synaptic signaling mechanisms . Key subfields include Dopamine neuron hyperexcitability , Glucocorticoid-endocannabinoid interactions , and Phosphodiesterase inhibition . Collaborations include work with institutions like the National Cancer Institute (NCI) and SWOG on clinical trials, though these appear tangential to his core neuroscience research.

Reza Shakerمشاهده پروفایل

استاد

• Gastroenterology
• Esophageal Motility
• Neonatal Medicine
• +۳ مورد دیگر

Reza Shaker, MD is a Professor and holds multiple administrative roles at the Medical College of Wisconsin (MCW), including Associate Provost, Senior Associate Dean, Center Director, and Chief. He specializes in Gastroenterology and Hepatology, affiliated with Froedtert Hospital and Zablocki VA Medical Center. His clinical expertise includes GERD, gastrointestinal motility disorders, swallowing disorders, and endoscopic treatments. Dr. Shaker’s education includes a Doctor of Medicine from Tehran University of Medical Sciences (1975), followed by surgical residencies in Tehran, London, and Brooklyn, concluding with a Gastroenterology fellowship at MCW (1985-1988). His research focuses on esophageal physiology, neonatal aerodigestive-cardiac interactions, and medical ethics. He has contributed to advancements in virtual medical systems (e.g., My Real Avatar) and IRB process optimization. Key research themes include esophageal motility mechanisms, neonatal cardiorespiratory dynamics, and translational oncology in esophageal adenocarcinoma. His work bridges clinical practice with technological innovation, addressing gaps in patient care delivery and ethical research practices. Collaborative projects emphasize interdisciplinary solutions for gastrointestinal disorders and healthcare efficiency. Dr. Shaker’s clinical services include endoscopy, manometry, and virtual consultations. He is fluent in English and Farsi, serving a diverse patient population. His academic contributions span teaching, mentorship in gastrointestinal specialties, and leadership in institutional research policies.

Kunal Guptaمشاهده پروفایل

استادیار

• Epilepsy
• Temporal Lobe Epilepsy
• Molecular Biology
• +۴ مورد دیگر

Dr. Kunal Gupta is an Assistant Professor in Neurosurgery at the Medical College of Wisconsin (MCW). He holds dual qualifications (MBChB and PhD) from the University of Cambridge and completed residency training at Oregon Health & Science University, followed by a fellowship in epilepsy and functional neurosurgery at Emory University. His clinical expertise focuses on surgical treatments for epilepsy and movement disorders, including Deep Brain Stimulation (DBS), Stereoelectroencephalography (SEEG), and Laser Interstitial Thermal Therapy (LITT). Research interests include molecular mechanisms of epileptogenesis, Wnt signaling pathways, and novel surgical techniques. The Gupta Lab investigates therapeutic targets to prevent epilepsy development using animal models and advanced techniques like transcriptomics and viral gene modulation. Collaborations span institutions like Indiana University and the University of North Carolina, focusing on neurosurgery, biomedical engineering, and plethysmography. Key contributions include developing educational curricula for vagus nerve stimulation and advancing computational methods for rodent electrophysiological analysis. Funding sources include NIH grants and the Neurosurgery Research & Education Foundation. His work has been published in journals such as Experimental Neurology , Nature Reviews Neurology , and Epilepsia . Education: MBChB - Doctor of Medicine, University of Cambridge (2006) Residency in Neurological Surgery, Oregon Health & Science University (2012-2019) Fellowship in Epilepsy Neurosurgery, Emory University (2019-2020) Labs/Teams: Gupta Lab at MCW’s Translational and Biomedical Research Center, specializing in epilepsy mechanisms and surgical innovations.

• Developmental Biology
• Systems Biology
• Cell Biology
• +۳ مورد دیگر

Jeroen van Zon is a Group Leader at AMOLF, focusing on Quantitative Developmental Biology. He holds a PhD in Theoretical Physics (2006) and a Physics degree (2002) from the Vrije Universiteit Amsterdam. His postdoctoral work included studying molecular noise in cell fate patterning at MIT (2008–2010) under Prof. Alexander van Oudenaarden. He has pioneered computational and experimental approaches to understand stochastic processes in developmental biology, particularly in C. elegans and intestinal organoids. Research Interests: Dr. van Zon’s work integrates biophysics, systems biology, and developmental biology to study cell fate decisions, tissue homeostasis, and noise-driven developmental processes. He develops tools like OrganoidTracker for quantitative cell tracking and employs CRISPR-based methods to study gene regulation in organoids. Key themes include: - Stochasticity in cell signaling and differentiation - Mechanisms of robustness in self-renewing tissues - Temporal coordination in whole-animal development Awards: - Human Frontier Science Program Fellowship (2008) Advancing Cell Tracking Technology: His lab has developed novel methods for live-cell imaging and error-prediction algorithms to study organoid dynamics. Collaborations span experimental biology, computational modeling, and engineering to bridge scales from molecular fluctuations to tissue-level patterns. AMOLF Affiliations: His group is part of AMOLF’s Physics of Behavior and Biochemical Networks research lines, leveraging interdisciplinary approaches to unravel fundamental biological principles.

Richard Hiteمشاهده پروفایل

استاد

• Structural Biology
• Cryo-electron microscopy
• X-ray crystallography
• +۵ مورد دیگر

Richard Hite, PhD, is a Professor and Principal Investigator in the Structural Biology Program at Memorial Sloan Kettering Cancer Center (MSKCC). He earned his PhD from Harvard University in 2010 and a BS from Emory University in 2003. His research focuses on the structural and functional mechanisms of ion channels and membrane proteins, particularly in cancer and neuroscience contexts. The Hite Lab employs advanced techniques like cryo-electron microscopy, X-ray crystallography, and electrophysiology to study lysosomal ion channels (e.g., TMEM175 and FLVCR1), DNA replication dynamics, and calcium signaling via IP3 receptors. Key contributions include identifying inhibitors for Parkinson’s disease-linked TMEM175 and elucidating choline transport mechanisms critical for phospholipid synthesis. Hite holds prestigious awards such as the Pershing Square Sohn Prize and Searle Scholar recognition. His lab has produced high-impact publications in Nature , Science , and Nature Communications , advancing understanding of membrane biology and disease mechanisms. Education: PhD, 2010, Harvard University BS, 2003, Emory University Research Interests: Dr. Hite’s work integrates structural biology with cellular and biochemical approaches to address fundamental questions in membrane protein function. Current projects explore the molecular basis of ion channel regulation, lysosomal physiology, and the structural determinants of disease-associated mutations. His lab’s findings have implications for therapies targeting cancer and neurodegenerative disorders. Grants & Collaborations: Hite collaborates with institutions like Weill Cornell Graduate School and the Tri-Institutional Program. His funding includes grants from the NIH and foundation awards. His lab actively recruits postdoctoral researchers and graduate students. Lab Members: The lab includes graduate students, research associates, and fellows working on projects ranging from cryo-EM structure determination to functional assays of ion channels. Notable students include Benjamin Allwein, Viktor Belay, and Yeeun Son.

Nina Marie Pedersenمشاهده پروفایل

دانشیار

• Cell biology
• Molecular biology
• Cancer research
• +۳ مورد دیگر

Nina Marie Pedersen is an Associate Professor in the Department of Nursing, Health and Bioengineering at Oslo and Akershus University College of Applied Sciences in Fredrikstad. Her research focuses on cell biology and molecular mechanisms underlying cancer progression, particularly the roles of endosomal systems in cell migration, invasiveness, and signaling pathways. She has published extensively on topics such as ER-endosome contact sites, protease shedding, and membrane trafficking. Key research interests include: Cancer cell invasiveness mechanisms Endosomal dynamics and their impact on cellular processes Protease regulation and metastasis Membrane contact site biology Recent work highlights contributions to understanding how endosomal protease shedding facilitates cancer cell invasiveness and the role of protrudin in ER-endosome interactions. Pedersen also collaborates on developing automated cell migration tracking tools (CellTraxx) and explores bioengineering applications in health sciences. Her teaching spans bioengineering foundations, cell/molecular biology, and molecular diagnostics. She leads the Biomedical Technology research group and actively contributes to interdisciplinary projects in health and bioengineering.

• Retinal Degeneration
• Ophthalmology
• Wnt Signaling Pathways
• +۳ مورد دیگر

Abigail Shoshana Hackam, Ph.D. is a Professor of Ophthalmology at the University of Miami's Bascom Palmer Eye Institute, where she serves as Director of Laboratory Research and Associate Director of the Master's of Science in Vision Science and Investigative Ophthalmology program. Her educational background includes: PhD in Human Genetics from Johns Hopkins University (1997) Post-Doctoral Fellowship in Ophthalmology at Johns Hopkins University (2003) Post-Doctoral Fellowship in Medical Genetics at the University of British Columbia, Vancouver (2000) Dr. Hackam's research focuses on cellular signaling mechanisms underlying retinal homeostasis and response to injury. Her laboratory investigates Wnt signaling pathways in optic nerve regeneration, the role of innate immunity in retinal degenerations, and dietary/environmental influences on ocular disease. She has developed a Müller glia-photoreceptor culture system for drug discovery related to photoreceptor survival. Analysis of her recent publications shows a strong emphasis on diabetic retinopathy, retinal degeneration mechanisms, and axonal regeneration approaches. Dr. Hackam serves on national and international grant review committees and actively promotes vision research through community outreach programs and mentoring early-career scientists. She teaches graduate-level courses including OPH630 (Ophthalmic Genetics), PIBS702, and NEU631 (Genetic Diseases of the Nervous System).

Josep F Abrilمشاهده پروفایل

پژوهشگر

• Computational Genomics
• Bioinformatics
• Molecular Biology
• +۶ مورد دیگر

Josep F. Abril is a researcher at the Universitat de Barcelona, leading the Computational Genomics Lab. He holds a MSc in Biology (UB, 1998) and a PhD in Genomics (UPF, 2005). His work focuses on computational analysis of eukaryotic genomes, including genome assembly, transcriptome analysis, and modeling molecular interactions. Key projects include the Smed454 dataset for planarian transcriptomics and tools like PlanExp and PPaxe for data integration. He has contributed to ENCODE and RGASP projects, and developed visualization tools like gff2ps. His research spans regenerative biology, virology, and genetic disease mechanisms. Awards include the Juan de la Cierva Postdoctoral Fellowship. He co-directed PhD theses on viral metagenomics and planarian stem cells, and collaborates across disciplines in genetics, bioinformatics, and public health. Education: MSc Biology (UB, 1998), PhD Genomics (UPF, 2005) Affiliations: Bioinformatics Unit, IBUB; Genetics Department, UB Research Interests: Computational genomics, transcriptomics, regenerative biology, viral metagenomics, and systems biology. Projects include planarian stem cell regulation, SARS-CoV-2 analysis, and genetic studies of bone diseases. Publications: Over 80 peer-reviewed articles, focusing on genome annotation, virology, and developmental biology. Recent work addresses coronavirus surveillance and regenerative signaling pathways. Grants & Students: Led a 2010–2012 research project grant; advised PhD candidates like Natàlia Timoneda and Gustavo Rodriguez-Esteban. Collaborates with groups in virology, genetics, and computational biology.

Terhi Heinoمشاهده پروفایل

استاد مدعو

• Regenerative Medicine
• Cell Biology
• Bone Tissue Engineering
• +۷ مورد دیگر

Terhi Heino is an Adjunct Professor (Docent) and University Lecturer in Cell Biology at the Institute of Biomedicine, University of Turku, Finland. She holds dual roles in teaching and research within the Faculty of Medicine. Her research focuses on mesenchymal stromal cells (MSCs), bone and vascular biology, biomaterials, and translational regenerative medicine applications. She has a PhD in Cell Biology (2005, University of Turku) and postdoctoral training at the Karolinska Institutet (Sweden). She became a Docent in Cell Biology in 2013. Her teaching spans histology, cell biology, pharmacology, and regenerative medicine at undergraduate and postgraduate levels, with international experience in Sweden and EU-funded interdisciplinary projects. Education: PhD in Cell Biology, University of Turku (2005) Postdoctoral Training, Karolinska Institutet (Sweden), 2006–2007 Docent Title in Cell Biology, University of Turku (2013) Pedagogic Qualification, Faculty of Education, University of Turku (2009–2014) Research Interests: Stem cell biology, biomaterial-cell interactions, osteogenesis, angiogenesis, bioactive materials, and translational regenerative medicine applications. Her research group investigates MSC differentiation pathways, bioactive materials for bone healing, and immunomodulatory effects of biomaterials. Recent studies include bioactive glass effects on macrophages and Rcor2 regulation in MSC differentiation. Teaching contributions include curriculum development, mentorship in biomedical programs, and international entrepreneurship education projects. She actively collaborates with multidisciplinary teams in Finland and Sweden. Publications highlight advancements in biomaterial characterization, molecular mechanisms in bone healing, and interdisciplinary approaches to musculoskeletal research. No scientific awards explicitly mentioned, though her work reflects sustained academic contributions.

Shrestha Sinha Rayمشاهده پروفایل

استادیار

• Neurology
• Gene Therapy
• Microbiology
• +۴ مورد دیگر

Dr. Shrestha Sinha Ray is an Assistant Professor in the Biology Department at Ohio Dominican University. She holds a Ph.D. in Microbiology and Cell Science from the University of Florida and completed postdoctoral training at Nationwide Children's Hospital, focusing on gene therapy and neurological disease modeling. Her research bridges cell/molecular biology and neuroscience, emphasizing in vitro models for rare neurological disorders and drug development. Education: Ph.D. Microbiology and Cell Science, University of Florida B.Tech. Biotechnology, VIT University Postdoctoral Training: Center for Gene Therapy, Nationwide Children's Hospital Research Interests: Dr. Ray's work focuses on developing cell culture models for diseases like spinal muscular atrophy and exploring gene therapy vectors. She also investigates Vibrio cholerae biofilm dynamics and bacterial genetics. Her interdisciplinary approach spans neurology, microbiology, and translational medicine. Publications: Over 15 peer-reviewed articles highlight her contributions to neurodegenerative disease modeling, AAV gene therapy efficacy, and microbial pathogenesis. Recent work includes promising in vitro/in vivo results for PGAP3-CDG syndrome and insights into ER stress mechanisms in ALS/FTD. Labs/Teams: Her lab at Ohio Dominican University focuses on translating in vitro models into therapeutic strategies for rare neurological conditions.

Abdullah Kahramanمشاهده پروفایل

مدرس

• Bioinformatics
• Cancer omics
• Alternative splicing
• +۳ مورد دیگر

Abdullah Kahraman is Group Leader of Data Science in Life Sciences and Lecturer at the Institute for Chemistry and Bioanalytics in the School of Life Sciences at the University of Applied Sciences and Arts Northwestern Switzerland (FHNW). He holds a Diploma in Bioinformatics from University of Applied Science Giessen-Friedberg and a PhD in Computational Biology from the University of Cambridge. His research focuses on computational methods for cancer omics, particularly using long-read sequencing to study alternative splicing in cancer development and therapy resistance. Kahraman develops bioinformatics tools for analyzing isoform switching events in tumors and applies machine learning to identify biomarkers and therapeutic targets. His work bridges computational biology and clinical oncology through collaborations with university hospitals in Zurich and Basel.

• Bone Biomechanics
• Osteoporosis
• Mineralization Disorders
• +۲ مورد دیگر

Simon von Kroge is an Associate Professor in the Department of Osteologie und Biomechanik at the University Medical Center Hamburg-Eppendorf (UKE). His research focuses on bone quality disorders including osteoporosis, mineralization defects, and skeletal regeneration, with particular emphasis on biomechanical properties and therapeutic interventions for bone loss. Research interests include: Genetic and metabolic bone diseases Bone-cartilage interactions in osteoarthritis Biomechanics of spinal and joint implants Mineralization processes in auditory ossicles Sex-specific bone aging patterns His recent publications demonstrate strong interdisciplinary focus on: Preclinical models of rare bone disorders Advanced imaging analysis of bone microstructure Novel biomaterials for skeletal reconstruction Geriatric fracture biomechanics Mechanotransduction pathways in skeletal tissues