جستجوی استاد راهنمای دانشگاهی

• Wheat Breeding
• Functional Genomics
• Molecular Biology
• +۳ مورد دیگر

Dr Chong Mei Dong is a Research Fellow at the University of Sydney's School of Life and Environmental Sciences, affiliated with the Sydney Institute of Agriculture. She joined the university in 2002 and focuses on non-transgenic gene modification methods and cereal genetics. Education: Bachelor's and Master's degrees from Fudan University, Shanghai, China PhD in wheat cell cycle gene research at Australian National University Postdoctoral research on wheat meiosis at University of Adelaide Research Interests: Cloning/functional analysis of genes, association studies linking genes to traits, TILLING technology for wheat breeding, cereal genetics, functional genomics, and molecular biology. Her work aligns with the university's research strengths in crop improvement and genomics. Key Research Trends: Recent studies emphasize genetic resistance to rust pathogens, genomic analysis of fungal pathogens (e.g., Austropuccinia psidii), and the application of modern biotechnologies like TILLING. Publications highlight wheat-rust interactions, carotenoid biosynthesis in fungi, and introgression line development for disease resistance. Grants & Collaborations: 2021: Accelerating genetic gain in wheat hybrid breeding (ACIAR) 2020: Stomatal manipulation for wheat yield improvement (GRDC) Labs & Teams: Active in Plant Breeding Institute (Cobbitty) and collaborates with international teams on hybrid breeding and pathogen genomics.

Ian Sudberyمشاهده پروفایل

مدرس ارشد

• Gene Regulation
• MicroRNAs
• Chromatin Structure
• +۴ مورد دیگر

Dr. Ian Sudbery is a Senior Lecturer in Bioinformatics at the School of Biosciences, University of Sheffield, a position he has held since 2022. Previously, he served as a Lecturer in Bioinformatics at the same institution from 2014 to 2022. His academic journey includes roles such as a CGAT Fellow at the MRC Functional Genomics Unit, University of Oxford (2011–2014), and Postdoctoral Research Fellowships at Harvard Medical School and the Wellcome Trust Sanger Institute. Dr. Sudbery earned his PhD in Functional Genomics from the Wellcome Trust Sanger Institute and the University of Cambridge (2003–2007). He has also held postdoctoral positions at Harvard Medical School and the Wellcome Trust Sanger Institute, focusing on systems biology and functional genomics. His research interests revolve around understanding gene regulation and its malfunction in diseases. Key areas include the role of microRNAs in regulatory networks, chromatin structure in disease contexts, and computational genomics methodologies. Specific topics include how microRNAs threshold gene expression, the interplay between enhancers and promoters in chromatin structure, and the application of computational tools to study these processes. His work spans topics such as miRNA function, chromatin-based regulatory rewiring in cancer, and the development of computational tools for genomic analysis, as evidenced by his publications in Nature , Nature Communications , and others. Collaborations with institutions like Imperial University explore chromatin structure's role in disease. His contributions include widely used tools like Alevin and UMI-tools for RNA-seq data analysis.

Emily Noëlمشاهده پروفایل

مدرس ارشد

• Heart Development
• Congenital Heart Defects
• Zebrafish Models
• +۳ مورد دیگر

Dr Emily Noël is a Senior Lecturer at the University of Sheffield's School of Biosciences. Her research focuses on understanding heart development and congenital defects using zebrafish models. She holds a British Heart Foundation Intermediate Basic Science Research Fellowship and has led projects on ECM dynamics and heart morphogenesis. Education : BSc Biochemistry (University of Warwick, 2001-2004) PhD Student in Ober Lab (National Institute for Medical Research, London, 2005-2009) Research Interests : Heart Development and Congenital Defects . Uses genetic editing (CRISPR-Cas9), live imaging, and quantitative analysis to study cell-ECM interactions during heart formation. Recent work emphasizes asymmetric ECM expansion and laminin roles in cardiac morphogenesis. Grants & Awards : British Heart Foundation Fellowship Academy of Medical Sciences/Wellcome Trust Grant Rosetrees Trust Funding Teaching : Leads courses in Developmental Biology, Biomedical Technology, and Disease Modeling at undergraduate/graduate levels. Supervises MSc and PhD students including Juliana Sánchez Posada and Emma Armitage.

Jiyuan Anمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Genomics
• High-dimensional data analysis
• +۵ مورد دیگر

Dr. Jiyuan An is a Bioinformatics Specialist at Queensland University of Technology (QUT), affiliated with the Faculty of Science's School of Biology & Environmental Science. He holds a PhD from the University of Tsukuba. His research focuses on bioinformatics methodologies, multi-omic data analysis, and genetic epidemiology with applications in plant biology, cancer genomics, and disease susceptibility studies. Key research interests include developing bioinformatics tools for high-dimensional data indexing, miRNA-target interactions, and transcript factor analysis. He has contributed to major projects like the multi-omic resource for Nicotiana benthamiana , which integrates genomic and transcriptomic datasets for plant research. His work also addresses genetic risk factors for gastroesophageal reflux, glaucoma, and melanoma using large-scale genomic studies. Dr. An has published extensively on topics ranging from AI-driven medical image analysis to Mendelian randomization studies evaluating causal relationships between lifestyle factors and diseases. His recent work explores genetic heterogeneity in mental health disorders and integrates multi-omic data to identify shared risk genes for allergic diseases. While no specific awards are noted, his research demonstrates significant contributions to both computational biology and translational genetics, with collaborations spanning plant science, oncology, and epidemiology. He contributes to open-access resources for genomic data analysis and has developed computational methods for transcriptomic and proteomic studies.

• Epigenetics
• Genomics
• Bioinformatics
• +۵ مورد دیگر

Dr. Kevin Dudley is a Research Officer (Genomics) at Queensland University of Technology (QUT), affiliated with the School of Biology & Environmental Science within the Faculty of Science. His research focuses on epigenetics, genomics, and bioinformatics, with particular expertise in DNA methylation mechanisms across diverse organisms including insects, plants, and microbes. He leads projects investigating the developmental origins of disease, molecular mechanisms of learned behaviors, and applications of epigenetics in bioproduction and environmental sensing. Completed PhD at the University of Keele (UK) in cancer epigenetics Joined QUT's Central Analytical Research Facility in 2013 Research interests include: Epigenetic regulation in Helicoverpa armigera (agricultural pest) Development of bioinformatics pipelines for novel species Integration of omics datasets for molecular phenotyping Advocacy for FAIR data principles and metadata standards Supervision highlights include topics such as microbial plastic degradation, genome annotation of Helicoverpa armigera, and multi-omics strategies for health and behavior studies. He collaborates with the Centre for Agriculture and the Bioeconomy and the Centre for Genomics and Personalised Health. Publications span 2008–2024, emphasizing genomic tools, epigenetic mechanisms, and applications in agriculture and biotechnology. Active on LinkedIn and ORCID.

• RNA interference
• Gene regulation
• Plant biotechnology
• +۴ مورد دیگر

Dr Felipe Fenselau de Felippes holds the position of Senior Research Associate within QUT's School of Biology & Environmental Science, part of the Faculty of Science. He completed his PhD at the Max Planck Institute for Developmental Biology (Germany) and postdoctoral research at ETH Zurich (Switzerland). His career has focused on RNA interference mechanisms in plants, particularly their roles in development, viral defense, and abiotic stress responses. Research interests include gene regulation via small RNAs, plant biotechnology applications, and genomic approaches to studying plant responses. He teaches BVB317 - Principles of Genomics and Biotechnology. Key contributions include work on transgene expression optimization using terminator elements and multi-omic analysis of Nicotiana benthamiana. Publications span plant stress responses, viral resistance mechanisms, and foundational studies in RNA silencing pathways. His work has been published in New Phytologist , Nature Plants , and Plant Journal . Current research emphasizes drought response strategies and translational plant biotechnology solutions.

• Cardiovascular Disease
• Metabolic Syndrome
• Vascular Physiology
• +۳ مورد دیگر

Dr. Maria Jelinic is a Senior Lecturer in the Department of Microbiology, Anatomy, Physiology & Pharmacology at La Trobe University. Her research focuses on cardiovascular and metabolic diseases, particularly hypertension, obesity, and diabetes. She investigates inflammatory mechanisms and novel therapeutic strategies using rodent models. Dr. Jelinic holds a PhD from the University of Melbourne (2017) and has secured $3.7M in competitive funding. She is actively involved in training the next generation of biomedical researchers. Research Interests: Mechanisms driving cardiac, vascular, and renal complications in cardiometabolic diseases Sex differences in metabolic syndrome progression Development of mouse models for human atherosclerosis Pharmacological interventions targeting immune cells to reduce end-organ damage Articles: Her recent work emphasizes hypertension mechanisms, metabolic syndrome, and single-cell transcriptomics. Studies include sex-specific effects of diets, IL-18's role in vascular pathology, and hesperidin's insulin-resistance impact. Grants & Funding: Over $3.7M secured, including an NHMRC/National Heart Foundation Early Career Fellowship (2018-2022). She collaborates widely and mentors HDR students. Labs/Teams: Active in the Centre for Cardiovascular Biology and Disease Research at La Trobe University.

Anne L Calofمشاهده پروفایل

استاد

• Developmental Biology
• Genetics
• Molecular Biology
• +۴ مورد دیگر

Anne L Calof is a Professor in the Department of Anatomy & Neurobiology at the University of California, Irvine (UCI), and holds an Adjunct Professor position at the Neurobiology and Cognitive Science Center, National Taiwan University. Her research focuses on developmental biology, genetics, and cohesin complex dysfunction in diseases like Cornelia de Lange Syndrome (CdLS). She is affiliated with UCI's Center for Complex Biological Systems and has contributed to studies on gene expression, embryonic development, and molecular mechanisms underlying congenital defects. Her work integrates mouse models, single-cell RNA sequencing, and genetic analysis to explore how cohesin mutations disrupt cell differentiation and organ formation. Key collaborations include projects with Arthur D. Lander and teams investigating Nipbl and Wapl gene roles in developmental disorders. She has authored influential papers on cohesinopathies, neural crest cell biology, and morphogenetic processes. Calof’s research also addresses translational applications, such as identifying therapeutic targets for CdLS and understanding regenerative mechanisms in neural tissues. Her interdisciplinary approach bridges developmental genetics, systems biology, and clinical insights.

Hao Fengمشاهده پروفایل

استادیار

• Biostatistics
• Bioinformatics
• Computational Biology
• +۳ مورد دیگر

Hao Feng, PhD, is an Assistant Professor in the Department of Population and Quantitative Health Sciences at Case Western Reserve University’s School of Medicine. He is also a member of the Population and Cancer Prevention Program at the Case Comprehensive Cancer Center. His research focuses on developing biostatistical and bioinformatics methods to analyze high-throughput omics data, particularly in epigenomics. He has created multiple open-source software tools (e.g., ISLET, magpie, NeuCA) widely used in disease studies, with over 10,000 annual downloads. Dr. Feng collaborates with clinical and wet-lab researchers to interpret cancer genomics data. Education: PhD in Biostatistics, Emory University (2019) MS in Biostatistics, Emory University (2018) MSPH in Biostatistics, Emory University (2013) BS in Biosciences, University of Science and Technology of China (2011) Research Interests: Dr. Feng specializes in statistical methods development for omics data, including epigenomics and transcriptomics. His work emphasizes practical applications in computational biology, such as identifying cancer subtypes via epigenetic biomarkers and improving cell-type-level inference through personalized genomics deconvolution. Recent projects include developing tools for power analysis in MeRIP-seq studies and neural network-based cell-type annotation. Grants & Funding: He leads the NIH/NIGMS Maximizing Investigators' Research Award (MIRA) grant (1R35GM154862), totaling $1.9M, focused on personalized genomics deconvolution. This work aims to enhance cell-type-level inference accuracy in complex biological systems. Labs & Teams: His lab (hfenglab.org) focuses on integrating statistical and computational approaches to solve challenges in precision medicine and cancer research. Collaborations span clinical oncology, neurobiology, and bioinformatics.

• Plant Biology
• Plant Signal Transduction
• Plant Gene Regulation
• +۴ مورد دیگر

Assoc Prof Ma Wei is an Associate Professor at the School of Biological Sciences, Nanyang Technological University (Singapore), specializing in plant molecular biology and lipid metabolism. He holds a PhD in Plant Science from the University of Connecticut (USA) and completed postdoctoral training at Michigan State University (USA). His lab focuses on understanding plant signal transduction, gene regulation, and lipid biosynthesis mechanisms, with a particular emphasis on improving seed oil yields through genetic engineering. He was promoted to Associate Professor with Tenure in 2024 and recognized as an EMBO Global Investigator in 2024. Education: PhD in Plant Science, University of Connecticut (USA) Postdoctoral Training, Michigan State University (USA) Research Interests: His research integrates molecular genetics, biochemistry, and systems biology to study plant lipid metabolism pathways. Key themes include: Transcriptional regulation of seed oil biosynthesis (e.g., WRINKLED1 regulatory networks) Protein engineering for enhanced oil production Crosstalk between lipid metabolism and plant signaling pathways Awards: EMBO Global Investigator (2024) Grants & Lab Activities: Current grants support projects on seed oil metabolic engineering and plant stress responses. His lab collaborates internationally to advance applications in biofuel production and sustainable agriculture. No listed advising students are currently visible. Labs/Teams: Maintains an active research group focused on plant lipidomics and genetic improvement strategies.

Grace Kenneyمشاهده پروفایل

استادیار

• Bioinorganic Chemistry
• Bacteriology
• Bioinformatics
• +۵ مورد دیگر

Grace Kenney is an Assistant Professor in the Department of Chemistry at the University of Pittsburgh . Her research bridges bioinorganic chemistry, bacteriology, and bioinformatics to uncover novel microbial enzymes and natural products. Focus areas include computational genome mining Metalloenzyme characterization Metallophore discovery in microbiomes Her work combines biochemical, biophysical, and computational approaches to address fundamental questions in microbial physiology while exploring applications in biocatalysis and human health. Scientific awards include: Merck Fellow of the Damon Runyon Cancer Research Foundation (2019-2023) Postdoctoral Fellow, Leading Edge Symposium (2022) Northwestern University Widom Scholar Award (2018) American Heart Association Predoctoral Fellowship (2014-2016) Rappaport Award for Research Excellence (2014) Presidential Fellowship (2012-2014)

Joel Baderمشاهده پروفایل

استاد

• Bioinformatics
• Computational Biology
• Synthetic Biology
• +۷ مورد دیگر

Joel Bader, PhD, is a Professor in the Department of Biomedical Engineering at Johns Hopkins University, with secondary appointments in Computer Science and memberships in the Institute of Computational Medicine and Institute of Genetic Medicine. He leads the Johns Hopkins Cancer Target Discovery and Development (CTD2) Center and serves as Interim Director of the High-Throughput Biology Center. His research focuses on bioinformatics, synthetic biology, and systems biology, particularly in cancer genomics, synthetic chromosome design (Sc2.0 project), and understanding genotype-phenotype relationships. Bader's work includes developing computational methods for disease mechanisms, synthetic biology applications, and biosafety technologies. He holds a BS from Lehigh University and a PhD from UC Berkeley, with postdoctoral training at Columbia University. Research Interests: Bioinformatics, synthetic biology, cancer metastasis, genomic engineering, and infectious disease. Key projects include the Sc2.0 synthetic yeast genome, breast cancer metastasis studies, and antibiotic tolerance in Mycobacteria. Bader co-invented the 454 Genome Sequencer and co-founded Neochromosome, Inc. Scientific Awards: NSF CAREER Award, AIMBE Fellow, Deputy Editor of PLOS Computational Biology. He has advised numerous students and collaborators, with over 150 publications in computational biology and synthetic biology. Lab and Affiliations: Leads the Bader Lab, collaborating with the Ewald lab on breast cancer research and the Karakousis lab on Mycobacterium tuberculosis. Key grants include NIH funding for CTD2 and synthetic biology initiatives.

Amy Cainمشاهده پروفایل

دانشیار

• Antibiotic Resistance
• Bacterial Genetics
• Microbial Pathogenesis
• +۳ مورد دیگر

Amy Cain is an Associate Professor and ARC Future Fellow at Macquarie University's School of Natural Sciences, affiliated with the ARC Industrial Transformation Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). Her research focuses on antibiotic resistance mechanisms in bacteria like Acinetobacter baumannii and Klebsiella pneumoniae, emphasizing genomic analysis, functional genomics, and novel antimicrobial development. She leads projects such as 'Microbial Junk Food: Developing Synthetic Platforms for Plastic Degradation' and 'Investigating Regulatory Circuits Controlling Drug Efflux Pumps.' Key research areas include bacterial virulence factors, horizontal gene transfer, and the evolution of multidrug resistance. Cain's work spans lab-based experiments and clinical applications, with contributions to understanding secondary effects of antibiotics and developing rapid diagnostic tools like the Hydrophobic Agent Permeability Assay (HAPA). Education: Not explicitly detailed in profile Grants/Projects: 14 active/completed projects including FAAB and MQRIS facilities Her awards include the ASM Frank Fenner Award (2022) and David Syme Research Prize (2024). Cain collaborates extensively, leveraging transposon mutagenesis and flow cytometry techniques to advance microbial research. Her lab's innovations in microfluidics and antimicrobial peptide design address global health challenges posed by drug-resistant pathogens.

Jonathan Diedrichمشاهده پروفایل

استادیار

• Cancer Biology
• Epigenomics
• Pharmacogenomics
• +۴ مورد دیگر

Jonathan Diedrich, PhD, is an Assistant Professor in the Department of Pharmacology & Toxicology at Michigan State University (MSU). His research focuses on cancer biology, epigenomics, and the role of tumor microenvironments in leukemia and other cancers. He holds a PhD in Cancer Biology from Wayne State University (2012-2017) and a B.S. in Zoology from MSU (2008-2012). His research interests include investigating inherited noncoding genetic variations impacting pharmacogenomics in childhood leukemia, epigenetic regulation in B-cell acute lymphoblastic leukemia (B-ALL), and the metabolic interactions between bone marrow adipocytes and metastatic tumors. His work bridges basic science and translational research, aiming to uncover mechanisms of drug resistance and tumor survival. Recent studies highlight his contributions to understanding the role of aryl hydrocarbon receptors in obesity-associated cancers and the impact of adipocyte-derived signaling molecules on tumor progression. He has secured funding from institutions such as the National Cancer Institute (NCI) and the National Institute of Environmental Health Sciences (NIEHS). Dr. Diedrich has published extensively on topics including chromatin architecture in leukemia, glucocorticoid resistance mechanisms, and the role of lipid metabolism in metastatic prostate cancer. His research has been published in high-impact journals like Nature Communications, Cell Genomics, and Leukemia.

Matthew Halvorsenمشاهده پروفایل

استادیار

• Obsessive-compulsive disorder
• Tourette syndrome
• Genetics
• +۵ مورد دیگر

Matthew Halvorsen, PhD, is an Assistant Professor in the Department of Genetics at the UNC School of Medicine, University of North Carolina at Chapel Hill. His research focuses on identifying genetic contributions to psychiatric disorders, particularly Obsessive-Compulsive Disorder (OCD) and Tourette Syndrome, using genomic approaches like exome sequencing, genome-wide association studies (GWAS), and transcriptome analysis. He investigates the role of rare and common genetic variants, including de novo mutations, and their effects on neurodevelopmental pathways. Recipient of an R21 grant from the National Institute of Mental Health (NIMH) for collaborative research on Tic Disorders. Active in large-scale genetic studies involving Scandinavian cohorts, integrating case/control data to accelerate risk gene discovery. Research Interests: Functional effects of genetic variants on the developing nervous system transcriptome Role of de novo mutations in psychiatric disorders Integration of whole exome and genome data for disease risk assessment Grants & Funding: R21 Grant (NIMH) – "Acceleration of risk gene discovery for Tic Disorders through large-scale collaboration" Labs/Teams: Directs a genetics research lab focused on psychiatric disorder genomics, collaborating with international clinician networks for data collection and analysis.