معرفی
Joel Bader, PhD, is a Professor in the Department of Biomedical Engineering at Johns Hopkins University, with secondary appointments in Computer Science and memberships in the Institute of Computational Medicine and Institute of Genetic Medicine. He leads the Johns Hopkins Cancer Target Discovery and Development (CTD2) Center and serves as Interim Director of the High-Throughput Biology Center. His research focuses on bioinformatics, synthetic biology, and systems biology, particularly in cancer genomics, synthetic chromosome design (Sc2.0 project), and understanding genotype-phenotype relationships. Bader's work includes developing computational methods for disease mechanisms, synthetic biology applications, and biosafety technologies. He holds a BS from Lehigh University and a PhD from UC Berkeley, with postdoctoral training at Columbia University.
Research Interests: Bioinformatics, synthetic biology, cancer metastasis, genomic engineering, and infectious disease. Key projects include the Sc2.0 synthetic yeast genome, breast cancer metastasis studies, and antibiotic tolerance in Mycobacteria. Bader co-invented the 454 Genome Sequencer and co-founded Neochromosome, Inc.
Scientific Awards: NSF CAREER Award, AIMBE Fellow, Deputy Editor of PLOS Computational Biology. He has advised numerous students and collaborators, with over 150 publications in computational biology and synthetic biology.
Lab and Affiliations: Leads the Bader Lab, collaborating with the Ewald lab on breast cancer research and the Karakousis lab on Mycobacterium tuberculosis. Key grants include NIH funding for CTD2 and synthetic biology initiatives.
