معرفی
Jef D. Boeke is the Sol and Judith Bergstein Director of the Institute of Systems Genetics and a Professor in the Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine. He holds a PhD from Rockefeller University and has pioneered research in synthetic biology, retrotransposition mechanisms, and yeast genetics. His work includes leading the international Sc2.0 project to synthesize the first eukaryotic genome and the 'Dark Matter Project' exploring non-coding DNA functions.
Research interests focus on genome engineering, synthetic genomics, epigenetics, and applications to cancer biology. His lab develops CRISPR tools and synthetic regulatory systems, with notable contributions to understanding LINE-1 retrotransposons and chromatin structure. Over 489 publications highlight his work in Nature Communications, Molecular Cell, and Science.
Awards: While specific prizes aren't listed, his leadership in groundbreaking projects like Sc2.0 and contributions to synthetic biology underscore his influential career. Grants and funding details are implied through active research programs.
Advising: Supervises a multidisciplinary team of postdocs and graduate students working on projects ranging from antibiotic engineering to de-extinction approaches. Lab collaborations include international partnerships and industry-driven biotech applications.
Labs/Teams: Directs the Boeke Lab, a hub for synthetic genome engineering and systems genetics. The lab’s interdisciplinary team bridges molecular biology, computational biology, and engineering to solve complex biological problems.
