جستجوی استاد راهنمای دانشگاهی

Elisa Gomez Perdigueroمشاهده پروفایل

دانشگاهی

• Immunology
• Developmental Biology
• Cell Biology
• +۹ مورد دیگر

Elisa Gomez Perdiguero is a Permanent Researcher at the Institut Pasteur in Paris, affiliated with the Membrane, Cytoskeleton and Cell Division unit. She leads the research group focused on the development, maintenance, and functions of tissue-resident macrophages, with a particular emphasis on their embryonic origins and roles in homeostasis and tissue repair. Her work bridges immunology, developmental biology, and cell biology, and she is the Principal Investigator of the ERC-funded project 'ResidentMacroPhage'. Her research primarily investigates the role of yolk sac-derived erythro-myeloid progenitors (EMPs) in generating tissue-resident macrophages such as microglia, Kupffer cells, and Langerhans cells, which self-maintain independently of hematopoietic stem cells (HSCs). She uses mouse and zebrafish models, along with advanced techniques like flow cytometry, lineage tracing, and transgenesis, to explore the ontogeny and functional specialization of macrophages during development and in response to injury. The trends in her recent publications highlight a consistent focus on developmental hematopoiesis, macrophage heterogeneity, and the interplay between macrophages and endothelial cells. Her work has demonstrated the critical role of early macrophage waves in shaping immune and vascular development, with implications for regenerative medicine and inflammatory diseases. Scientific awards and recognitions include: ERC-2016-StG _ResidentMacroPhage – Development, Maintenance and Functions of Resident Macrophages She has actively mentored numerous PhD students and postdoctoral researchers, including Lorea Iturri, Rebeca Ponce Landete, Alina Sommer, and others. Her lab has received funding from major programs such as LabEx Revive and the IP Stem Cell Initiative, supporting research in regenerative biology and medicine. She is currently recruiting for fully funded postdoctoral and PhD fellowships. Elisa Gomez Perdiguero's team collaborates within transversal programs such as 'Mother and Child Health' and participates in the broader Institut Pasteur ecosystem focused on precision medicine and open science.

İbrahim DEMİRTAŞمشاهده پروفایل

استاد

• Biochemistry
• Natural Products Chemistry
• Antioxidant Research
• +۳ مورد دیگر

İbrahim DEMİRTAŞ is a Professor at the Department of Biochemistry, Faculty of Science and Letters, Iğdır University. He holds a Doctorate in Chemistry from the University of Newcastle Upon Tyne (1994-1998), a Master's in Organic Chemistry from Atatürk University (1990-1992), and a Bachelor's in Chemistry from Atatürk University (1986-1990). His research focuses on natural product chemistry, with a particular emphasis on phytochemical isolation, antioxidant activity, anticancer agents, and molecular docking studies. He has contributed to over 198 publications, including studies on plant extracts from Loofah, Senecio massaicus, and Astragalus species. Notable awards include the Prestigious Scientist Award (2021) and recognition from TÜBİTAK (2015). He has supervised 22 thesis students, including works on Centaurea derderiifolia, Astragalus leucothrix, and Nigella sativa. His administrative roles include serving as Dean at Iğdır University and Çankırı Karatekin University. Education: PhD: University of Newcastle Upon Tyne (Chemistry, 1998) MSc: Atatürk University (Organic Chemistry, 1992) BSc: Atatürk University (Chemistry, 1990) Research Highlights: Development of natural product-based anticancer agents Investigation of antioxidant properties in plant extracts Molecular docking for drug discovery targeting Alzheimer's and Covid-19 Awards: Prestigious Scientist Award (2021) 2241-B Industrial Thesis Competition (2015) Grants and Projects: Lead researcher in cancer-related projects and natural product studies Collaborations on propolis, thyme, and Astragalus spp. research Supervised Students: PhD/MSc theses on bioactive compounds from endemic plants Teaching: Courses include Organic Chemistry, Spectroscopic Analysis, and Advanced Topics in Biochemistry

Ninan Abrahamمشاهده پروفایل

استاد

• Immunology
• Cell and Developmental Biology
• Lymphocyte Development
• +۳ مورد دیگر

Ninan Abraham is a Professor at the Department of Zoology, University of British Columbia, and affiliated with the Life Sciences Institute. His research focuses on immunology and cell biology, particularly the role of interleukin-7 (IL-7) in lymphocyte development, immune responses to viral infections, and cancer immunology. He leads the Abraham Lab, which investigates mechanisms of immune suppression in tumors, T cell differentiation, and cytokine signaling pathways. Research Trends: His recent work examines how tumor-secreted CCL5 drives immunosuppression in lung cancer (2022), the role of CD4⁺ Trm cells in anti-tumor responses, and peripheral blood biomarkers for immune checkpoint therapy efficacy. Earlier studies (2011-2016) explored IL-7Rα signaling pathways, STAT5's role in lymphomagenesis, and glucocorticoid regulation in lymphoid organs. Key Collaborations: Affiliated with the Canadian Society for Immunology and involved in cross-disciplinary projects at the intersection of zoology, microbiology, and immunology research.

Rachel Golubمشاهده پروفایل

استاد

• Innate lymphoid cell biology
• Notch signaling
• Hepatocellular carcinoma
• +۴ مورد دیگر

Rachel Golub is a Professor of Immunology at Université Paris Diderot (Paris 7) and heads the Lymphopoiesis Unit at the Institut Pasteur, INSERM U668, in Paris. Her research centres on innate lymphoid cell (ILC) biology, Notch signalling, and their implications in liver cancer, inflammation, and tissue regeneration. Education: PhD in Developmental Biology, Université Paris 6, 1997 HDR (Habilitation), Université Paris 7, 2007 Research Interests: Professor Golub investigates how innate lymphoid cells develop from fetal and adult progenitors, the molecular circuits controlled by the Notch pathway that balance ILC subsets, and how these pathways influence hepatocellular carcinoma progression and inflammatory diseases. Her team combines single-cell approaches, genetically modified models, and human tissue analysis to dissect microenvironmental cues shaping ILC fate. Publication Trends: Between 2020 and 2024 her work has appeared in leading journals such as Cell Reports , Immunity , EMBO Journal , Blood , and Frontiers in Immunology . The studies cluster around four main axes: (1) ILC differentiation and ontogeny, (2) Notch-mediated regulation of ILC and NK cells, (3) tumour-immune interactions in hepatocellular carcinoma, and (4) inflammatory modulation of lymphocyte development in metabolic and wound-healing contexts. Scientific Awards & Recognition: Prime d’Excellence Scientifique (PES) 2012-2016 PEDR Award 2007-2011 INSERM CSS7 third-rank distinction 2014 Fellowships from Ligue Nationale contre le Cancer, MRC Canada, Ontario Cancer Institute, and French Ministry of Research Grants & Advising: She has served as coordinator or collaborator on >15 major grants (ANR, ARC, INCA, FACCTS, USPC, ABM, PTR), funding post-doctoral and doctoral students as well as collaborative international projects. She regularly sits on HDR and PhD juries, ANR panels, and foreign funding agencies (DFG). Labs & Teams: Her Lymphopoiesis Unit at Institut Pasteur hosts the “ILC Development and Inflammation” group, currently comprising PhD students, engineers, and technicians. The team is embedded within the wider Pasteur Immunology Department and benefits from institute-level platforms such as Single-Cell Biomarkers and advanced imaging core facilities.

Henrik Holbechمشاهده پروفایل

دانشیار

• Ecotoxicology
• Endocrine Disruptors
• OECD Test Guidelines
• +۲ مورد دیگر

Henrik Holbech is an Associate Professor in Ecotoxicology at the University of Southern Denmark 's Department of Biology. With over 124 research outputs, his work focuses on developing OECD test guidelines for identifying endocrine disrupting chemicals (EDCs) using fish and invertebrate models, particularly Danio rerio (zebrafish). He coordinates the EU Horizon 2020 ERGO project (€5.99M) and leads multiple Nordic Council-funded initiatives on mollusc endocrinology. As chair of the OECD Mollusc Expert Group and member of the ECHA Endocrine Disrupter Expert Group , he bridges human health and environmental toxicology through adverse outcome pathway (AOP) research. Research Contributions: Developed and validated Fish Sexual Development Test (FSDT) protocols (OECD TG 230/210/229) Pioneered mollusc-based EDC testing for aquatic invertebrates Lead author of OECD validation reports Contributor to 40+ international technical meetings Created ELISA methods for vitellogenin detection in fish Investigated ballast water treatment technologies (UV/cavitation/ozonation) Explored thyroid hormone disruption mechanisms in aquatic species Collaboration Network: Active in EU Tender projects with University of Heidelberg, University of Antwerp; Nordic Council partnerships (NordUTTE) with Norway/Sweden; Danish EPA collaborations (5.2 Mio DKK total). Key institutions: DHI Hoersholm, Fraunhofer, University of Antwerp.

• Immunology
• Molecular Biology
• T-Cell Biology
• +۳ مورد دیگر

Vigo Heissmeyer is a Professor at the Ludwig-Maximilians-Universität München and leads the Department of Molecular Immunoregulation at Helmholtz Munich. His research focuses on decoding molecular mechanisms of T-cell-mediated immune responses, aiming to develop future therapies for autoimmune diseases and cancer immunotherapy. PhD in Signal Transduction at MDC Berlin Postdoctoral Fellowship at Harvard Medical School His work centers on post-transcriptional gene regulation via RNA-binding proteins and mRNA modifications in T cells, exploring their roles in development, activation, differentiation, and effector/memory cell formation. This research bridges pathogen defense, tumor immunity, and dysregulation leading to autoimmunity/inflammation. Recent publications highlight his contributions to understanding T-cell receptor signaling, RNA modifications (e.g., N6-adenosine methylation), and immune checkpoint mechanisms (e.g., Roquin-1/Regnase-1 interactions). Themes include immunotherapy, autoimmune disease, and RNA biology. 2011: ERC Starting Grant Heissmeyer’s group utilizes mouse models and primary cell systems, integrating molecular and cellular immunology with biochemical approaches to study immune regulation. Collaborations with institutions like Harvard Medical School and Helmholtz Zentrum München underscore his interdisciplinary focus.

Lisa K. Nolanمشاهده پروفایل

استاد

• Bacterial Pathogenesis
• Veterinary Microbiology
• Zoonotic Diseases
• +۳ مورد دیگر

Dr. Lisa K. Nolan is the Georgia Athletic Association Distinguished Professor and Dean of the University of Georgia’s College of Veterinary Medicine. She previously held leadership roles at Iowa State University and North Dakota State University, including Dean, Associate Dean, and Department Chair. Her expertise lies in bacterial pathogenesis affecting animal and human health, with a focus on Escherichia coli strains causing avian colibacillosis and human urinary/urinary tract infections. Education: BS from Valdosta State College; DVM, MS, and PhD from the University of Georgia. Research Interests: Bacterial zoonotic diseases, antimicrobial resistance, and E. coli virulence mechanisms. She has pioneered studies on avian pathogenic E. coli (APEC) and their overlap with human pathogens, particularly neonatal meningitis strains. Key Awards: AAAS and American Academy of Microbiology Fellowships, Honorary Diplomate of the American Veterinary Epidemiology Society, and Distinguished Educator Award from Blue Key National Honor Society. Her work bridges veterinary and human medicine, emphasizing One Health approaches to combat antimicrobial resistance and foodborne pathogens.

Isaak Quastمشاهده پروفایل

پژوهشگر ارشد

• Immunology
• Vaccine Development
• B-cell Biology
• +۴ مورد دیگر

Isaak Quast is a Senior Research Fellow in the Department of Immunology at Monash University, affiliated with Alfred Hospital. His research focuses on B-cell biology, vaccine design, and immune memory mechanisms. He leads projects funded by prestigious organizations such as the NHMRC (Australia) and the Swiss National Science Foundation, investigating topics like IL-21 signaling, germinal center dynamics, and precision mRNA vaccines. His work contributes to UN Sustainable Development Goals related to health and innovation. Key projects include 'Structure-based antigen design as a novel strategy for precision mRNA vaccines' and 'Manipulating antibody production to maximize memory in vaccine responses.' His research explores how cytokines like IL-21 regulate B-cell activation and germinal center formation, with implications for personalized vaccination strategies. Quast's publications highlight insights into B-cell memory during viral infections (e.g., SARS-CoV-2), plasma cell lifespan, and antibody affinity maturation. He collaborates with global researchers to advance understanding of immune responses and combat autoimmune diseases and infectious pathogens. His lab, the Immune Memory Lab (Monash University), hosts interdisciplinary teams studying long-lived immune responses. Current work emphasizes translating immunological discoveries into clinical applications, such as optimizing vaccine efficacy through antibody engineering.

Josef Penningerمشاهده پروفایل

استاد

• Molecular Biotechnology
• Functional Genetics
• Organoid Development
• +۶ مورد دیگر

Professor Josef Penninger is a leading molecular biotechnologist and Scientific Director of the Helmholtz Centre for Infection Research (HZI) in Braunschweig since 2023. He previously served as Canada 150 Chair at the Life Sciences Institute, University of British Columbia (2018-2023), and as Executive Director of the Austrian Academy of Sciences' Institute of Molecular Biotechnology (IMBA) from 2002-2018. His career spans institutions in Austria, Canada, and Japan, with a 2024 PhD in Medical Science from Tokyo Medical and Dental University. His research focuses on organoid development , glycoproteomics , and host-pathogen interactions , with significant contributions to understanding viral entry mechanisms and immune regulation . His work bridges biomedical engineering and developmental biology , particularly in vascular and intestinal organoid systems . His recent publications highlight innovative approaches in vascularized organoids , bat antiviral immunity , and metabolic pathways in aging . The 2023-2025 articles demonstrate expertise in CRISPR screening , microfluidic platforms , and glycan-based disease mechanisms . Scientific honors include the Ernst Jung Prize for Medicine , Descartes Prize , and Wittgenstein Prize (Austria's highest scientific award). He has held multiple ERC Advanced Grants and been recognized as a Highly Cited Researcher by Clarivate. Penninger mentors through the Penninger Lab in Vienna, Braunschweig, and Vancouver, with former advisees including Gustav Jonsson (PhD 2025) and Max J. Kellner (PhD 2025). His research groups integrate interdisciplinary teams across three continents , focusing on cancer , immunity , and biomedical innovation .

Ana Cumanoمشاهده پروفایل

استاد

• Immunology
• Hematopoiesis
• Lymphocyte Development
• +۳ مورد دیگر

Ana Cumano is a Professor at the Pasteur Institute and Research Director of Exceptional Class at INSERM, leading the Lymphopoiesis Unit with over four decades of groundbreaking research in immunology and hematopoiesis. She received her Doctoral degree in Medicine from the New University of Lisbon in 1980 and completed postdoctoral training at the Genetics Institute in Cologne and the Ontario Cancer Institute in Toronto before joining the Pasteur Institute in 1992. Her research focuses on lymphocyte development, particularly T cell development in the thymus, with significant contributions to understanding the waves of embryonic, fetal, and postnatal multi-lymphoid progenitors. Dr. Cumano's laboratory has pioneered the use of spectral cytometry for deep immunophenotyping and revealed fundamental insights into how bone marrow monocytes sustain NK cell development during liver inflammation through IL-15 trans-presentation and osteopontin secretion. Her recent publications demonstrate a consistent trajectory of innovative research, with 2025 work on spatiotemporal dynamics of fetal liver hematopoietic niches, 2024 studies on NK cell development during non-alcoholic steatohepatitis and high-dimensional spectral cytometry, and 2023 publications mapping human lymphopoiesis revealing differential regulation of B and T/NK/ILC lineages. Her research has established that lymphoid specification follows independent direct or stepwise hierarchical routes converging toward CD117lo multi-lymphoid progenitors. EMBO Member (2000-2014) National ARC Commission for Immunology, Microbiology, and Hematopoiesis (2009-2011, Vice-president 2012-2014) Scientific Council of the Pasteur Institute (2009-2013) COMESP Pasteur Institute member (2014-present) HERM Advisory Board, Stockholm (2014-present) As an educator, Dr. Cumano co-directs the Advanced Immunology course at the Pasteur Institute and has mentored numerous students and postdoctoral fellows. Her laboratory continues to investigate the role of lncRNA H19 in thymopoiesis and the developmental cartography of human lymphopoiesis, with implications for understanding immune disorders, blood cancers, and immunodeficiency conditions.

Maria Africa Gonzalez Fernandezمشاهده پروفایل

استاد

• Immunology
• Cell Biology
• Biomedicine
• +۲ مورد دیگر

Maria Africa Gonzalez Fernandez is a Full Professor of Immunology in the Department of Biochemistry, Genetics and Immunology at the Faculty of Biology, University of Vigo, where she maintains active affiliation with the Biomedical Research Center (CINBIO) and leads the IN1 Immunology research group. Her academic foundation includes: Doctorate in Medicine and Surgery from Universidad de Alcalá (1991) with thesis on 'Mechanisms of proliferation and cell death in human thymus' Specialist certification in Immunology via Spain's MIR residency system Her research centers on Immunology with emphasis on cellular and molecular mechanisms of immune responses, particularly thymic T-cell development and proliferation/death pathways. She actively bridges laboratory science and public understanding through her popular science book 'Inmuno Power: Conoce y fortalece tus defensas' (Inmuno Power: Know and strengthen your defenses), making complex immunological concepts accessible to non-specialists. Her distinguished recognition includes: Academic membership in the RAFG (Real Academia de Farmacia de Galicia) She has held significant leadership roles including Director of the Biomedical Research Center (CINBIO) from 2009-2019 and President of the Spanish Society of Immunology (2016-2020), demonstrating sustained impact on institutional and national scientific communities. As principal investigator of the IN1 Immunology research group at CINBIO, she directs multidisciplinary efforts integrating basic immunological research with translational biomedical applications, focusing on cellular immunity mechanisms and their clinical implications.

Marcin Tabakaمشاهده پروفایل

پژوهشگر

• Computational Genomics
• Single-Cell Genomics
• Cell Reprogramming
• +۳ مورد دیگر

Marcin Tabaka, PhD is a Group Leader at the International Centre for Translational Eye Research (ICTER), which is part of the Institute of Physical Chemistry, Polish Academy of Sciences in Warsaw, Poland. He leads the Computational Genomics Group focused on applying high-throughput single-cell genomics technologies to diverse research areas including eye research, cell reprogramming, immunology, and cancer. Dr. Tabaka graduated from the Jagiellonian University Faculty of Chemistry in 2004 and obtained his PhD at the Institute of Physical Chemistry, Polish Academy of Science (IPC PAS) in 2009. He completed postdoctoral training in Mathematical Biology at IPC PAS (2010-2014) followed by research at the Klarman Cell Observatory headed by Aviv Regev at the Broad Institute of MIT and Harvard (2014-2019). He established his independent research group at ICTER in September 2020. His research focuses on computational approaches to single-cell genomics, with applications in translational eye research and disease mechanisms. His work spans multiple disciplines including: Computational biology and bioinformatics Single-cell and single-nucleus RNA sequencing Developmental biology and cell reprogramming Immunology and cancer biology Retinal degeneration and eye disease mechanisms Dr. Tabaka's research group has developed several computational tools for single-cell data analysis, including the recently published "Ocelli" open-source platform for developmental multimodal single-cell data analysis. His work demonstrates strong interdisciplinary collaboration between computational biology, molecular biology, and clinical research, particularly in the field of ophthalmology. Dr. Tabaka is actively involved in mentoring researchers and collaborating on multiple interdisciplinary projects, though specific students are not listed in the available information. His research is supported by institutional funding from ICTER and likely external grants related to his publications in high-impact journals. He leads the Computational Genomics Group at ICTER, which maintains strong collaborations with international research institutions including the Broad Institute of MIT and Harvard. The group combines computational expertise with experimental approaches to address fundamental questions in genomics and translational medicine, particularly in the context of eye diseases.

Yihua Wangمشاهده پروفایل

دانشیار

• Cell Signalling
• Epithelial-Mesenchymal Crosstalk
• Pulmonary Fibrosis
• +۳ مورد دیگر

Dr. Yihua Wang is an Associate Professor at the School of Biological Sciences, University of Southampton, specializing in Cell Signalling in Disease , Epithelial-Mesenchymal Crosstalk , and Pulmonary Fibrosis . With over 80 peer-reviewed publications in journals like The Lancet Respiratory Medicine and PNAS , their work bridges cancer biology and chronic lung diseases. Research Focus: Idiopathic Pulmonary Fibrosis (IPF) pathogenesis, hypoxia signaling, and precision oncology Teaching: Module Coordinator for second-year Pharmacology, with cross-faculty engagement in Chemistry Scientific Awards: MRF Skills Training And Development Award Research Trends: Recent publications emphasize radiation-induced lung injury , EMT dynamics , autophagy in fibrosis , and cross-disciplinary toxicology (e.g., brake wear particle impact on lung cells). Collaborative projects span UK-China networks and multi-institutional therapeutic antibody validation. Supervision: Currently mentoring 11 PhD students across Biological Sciences and Biomed programs, with focus areas in lung fibrosis, neuroblastoma, and stress signaling.

• Food Allergy
• Food Safety
• Bioactive Compounds
• +۳ مورد دیگر

Dr. Ouarda Azdad is a researcher at Sidi Mohamed Ben Abdellah University's Faculty of Science and Technology of Fes, Morocco, active from 2016 to 2020. Affiliated with the Laboratory of Bioactive Molecules (LMBSF), her work centers on food science and allergy research, particularly interactions between food components and human health in the Moroccan context. Her primary research interests include food allergy, food safety, and bioactive compounds. She investigates allergenic properties of milk and fish, the impact of processing on allergenicity, and health benefits of natural products. Her studies often focus on the Fez-Meknes region population. Analysis of her publications (2016-2018) shows consistent focus on food allergens and processing effects. Key themes include reduction of allergenicity through heat and enzymatic treatments, and population-specific allergy patterns in Morocco, contributing to public health strategies. Dr. Azdad has received research grants from the National Natural Science Foundation of China and the International Fund for Agricultural Development, among others, supporting her investigations into food safety and allergy. She works within the Laboratory of Bioactive Molecules, which explores natural compounds for health applications, aligning with her research on food components and human health.

• Pediatric Surgery
• Bariatric Surgery
• Traumatic Brain Injury
• +۲ مورد دیگر

Matthew Alan Hornick, MD is an Assistant Professor of Surgery (Pediatrics) at Yale School of Medicine. A pediatric surgeon specializing in conditions affecting newborns to young adults, Dr. Hornick combines clinical practice with research in surgical outcomes and pediatric healthcare innovation. Education: MD from Yale School of Medicine (2017) Residency: Hospital of the University of Pennsylvania (2018) Clinical Fellowship: Children's Hospital of Philadelphia (2020) Research focuses on improving pediatric surgical care through evidence-based approaches, with particular emphasis on: Pediatric bariatric surgery outcomes Minimally invasive hernia repair techniques Diagnostic imaging optimization for traumatic brain injuries Metabolic and skeletal impacts of weight-loss procedures His publications from 2020-2025 span journals like Journal of Pediatric Surgery and Obesity Surgery , covering clinical decision-making, surgical innovation, and postoperative care quality. Collaborations include researchers from Children's Hospital of Philadelphia and Yale Medicine teams. Currently practicing at Yale New Haven Children's Hospital, Dr. Hornick maintains active roles in: Pediatric surgical care delivery Clinical research through Yale Center for Clinical Investigation Mentorship in surgical training programs Advancing data-driven surgical practices