جست‌وجوی استاد و پژوهشگر

• Molecular Biology
• Biochemistry
• Structural Biology
• +۳ مورد دیگر

Dr. Yuhong Zuo is a Researcher in the Department of Pharmacology at Yale University School of Medicine. She holds a PhD in Biochemistry & Molecular Biology from the University of Miami (2002), with earlier degrees including an MS in Chemistry (University of Miami, 1996) and BS in Applied Chemistry (Peking University, 1990). Her research focuses on structural and mechanistic studies of RNA polymerase, transcription initiation complexes, and exoribonuclease enzymes. Key areas include bacterial transcription regulation, RNA processing pathways, and protein-DNA interactions. Dr. Zuo has contributed to over 20 peer-reviewed papers since 1996, with recent work elucidating transcription mechanisms in E. coli and structural insights into RNA polymerase function. She serves as a reviewer for journals like Journal of Biological Chemistry and Molecular Cell , and has held prestigious awards including the American Heart Association Postdoc Fellowship (2003, 2005) and the Maytag Fellowship (1994). Education: PhD: Biochemistry & Molecular Biology, University of Miami, 2002 MS: Chemistry, University of Miami, 1996 MS: Radiochemistry, Shanghai Institute of Nuclear Research, 1993 BS: Applied Chemistry, Peking University, 1990 Research Highlights: Crystallographic studies of E. coli RNA polymerase and σ-factors Structural basis of transcription initiation/elongation transitions Functional analysis of exoribonucleases (RNase T, RNase R, etc.) Regulation of transcription by ppGpp and RapA proteins Her work bridges structural biology with enzymology, advancing understanding of fundamental biological processes and potential therapeutic targets in bacterial systems.

• Biophysical Chemistry
• Inorganic Chemistry
• Protein Structure and Function
• +۳ مورد دیگر

Filipe Alexandre Ferreira is an Assistant Professor at the NOVA School of Science and Technology, NOVA University Lisbon. His research focuses on applying Mössbauer Spectroscopy, Electron Paramagnetic Resonance (EPR), and Density Functional Theory (DFT) to study proteins, particularly the chemical characteristics of iron active sites and enzymatic mechanisms. He holds a Ph.D. in Chemistry from Carnegie Mellon University (2006), an M.Sc. in Chemistry from the same institution (2004), and a Degree in Physical Engineering from NOVA University Lisbon (1994). His academic credentials also include Pedagogical Aptitude and Scientific Capacity Tests in Biophysics (2000). His work integrates experimental and computational methods to elucidate biochemical processes, emphasizing interdisciplinary approaches between chemistry and biology. Contact him via fto@fct.unl.pt or at Cabinet 220, Building I – South Wing.

Dieter Söllمشاهده پروفایل

استاد پژوهشی

• Molecular Biology
• Biochemistry
• Genetics
• +۴ مورد دیگر

Dieter Söll is a Sterling Professor Emeritus and Research Professor in Molecular Biophysics and Biochemistry at Yale University, also holding an Emeritus title in Chemistry. He received his PhD in Chemistry from the Technische Hochschule Stuttgart (1962) and conducted postdoctoral research under H.G. Khorana at the University of Wisconsin, contributing to the elucidation of the genetic code. Since 1967, he has led a research group at Yale, mentoring over 250 trainees. His work focuses on transfer RNA (tRNA), aminoacyl-tRNA synthetases, and the genetic code, with groundbreaking contributions to selenocysteine and pyrrolysine research. Söll co-founded Nucleic Acids Research and pioneered educational initiatives like a summer program for underrepresented students. He is a member of prestigious academies and has been honored with awards such as the Humboldt Research Award and Guggenheim Fellowship. Research interests span genetics, molecular biology, and synthetic biology, emphasizing tRNA's role in protein biosynthesis and genetic code expansion. Recent studies explore selenocysteine's therapeutic applications and archaeal genetic innovations. His legacy includes over 665 papers and foundational contributions to understanding life's molecular machinery. Awards: Sterling Professorship (2006), US National Academy of Sciences membership, honorary doctorate from Uppsala University. Education Initiatives: Creator of a model summer research program, recipient of Bouchet Leadership Award for mentoring. Labs/Teams: Dynamic research lab at Yale focused on tRNA synthetases and genetic code engineering.

Caroline Kardebyمشاهده پروفایل

مدرس

• Thrombosis
• Platelet Activation
• Endothelial Cell Signaling
• +۳ مورد دیگر

Dr Caroline Kardeby is a Lecturer in Biosciences at Aston University, affiliated with the School of Biosciences and the Aston Research Centre for Health in Ageing within the College of Health and Life Sciences. She holds a PhD in Medical Science (Biomedicine) and is a Marie Curie Alumni Fellow and Advance HE Fellow. Her research focuses on thrombosis in inflammation, particularly the role of platelet and endothelial cell activation in vascular remodeling and neurodegeneration. She has pioneered studies using novel pharmacological tools to elucidate cardiovascular disease mechanisms. Dr Kardeby's education includes a PG Cert in Learning & Teaching (Aston University, 2025), a PhD from Uppsala University (2019), and multiple advanced degrees in biomedical sciences from Uppsala and Örebro Universities. Her clinical background includes registration as a biomedical scientist in Sweden, with experience in clinical chemistry, histology, and fertility laboratories. Her current research projects include investigating thrombotic risks in Parkinson’s disease (funded by the British Heart Foundation) and studying cardiovascular disease risk in South Asians (funded by the Listers Group and Aston University). She also leads a Dunhill Medical Trust-funded study on haemostatic dysregulation as a dementia biomarker. Dr Kardeby’s scientific awards include a Marie Skłodowska-Curie Actions Fellowship (2020-2022) and an Advance HE Fellowship (2025). Her lab includes postdoctoral researcher Dr Marcela Usmari Moraes and students Nusratul Firdaus and Cerys Charles. She actively collaborates with NHS Trusts and international institutions on thrombosis and vascular research.

Louise Serpellمشاهده پروفایل

استاد

• Protein self-assembly
• Protein misfolding
• Structural biology
• +۱۰ مورد دیگر

Louise Serpell is a Professor of Biochemistry and Director of Sussex Neuroscience at the University of Sussex since 2010 and 2019 respectively. Her research focuses on structural biology of amyloidogenic proteins in neurodegenerative diseases, particularly Alzheimer’s disease. She leads a multidisciplinary virtual center with 50 principal investigators and oversees a four-year doctoral program. Education : BSc in Biochemistry and Genetics (University of Nottingham, 1989-1992); DPhil in Structural Studies of Amyloid Proteins (University of Oxford, 1992-1995). Her work spans structural biology , molecular biophysics , and cellular neuroscience , emphasizing amyloid fibril formation, protein misfolding, and neurodegenerative disease mechanisms. She has pioneered high-resolution imaging techniques like synchrotron X-ray diffraction and electron microscopy to elucidate amyloid structures. Recent research trends include: Mechanistic studies of amyloid-beta and tau protein aggregation Role of metal catalysis in protein misfolding Impact of endosomal-lysosomal dysfunction in Alzheimer’s disease Development of atomic-resolution models for amyloid nanofibers Scientific Awards & Recognition : Sussex Impact award (2016) RED Women’s Awards "Pioneer" category (2013) Royal Society University fellowship (2000) Two papers cited over 1,000 times (1997, 2000) She has served on grant panels (BBSRC, UKRI FLF, Alzheimer's Society) and editorial boards (Journal of Molecular Biology, Frontiers in Molecular Biosciences). Her team has supervised 14 PhD students and 12 postdoctoral researchers, with over £5.5M in total grant income. She actively promotes public engagement and equality initiatives, organizing the Rosalind Franklin Women in Science symposium.

Claudius Lenzمشاهده پروفایل

پژوهشگر

• Natural Product Chemistry
• Fungal Biotechnology
• Tryptamine Biosynthesis
• +۵ مورد دیگر

Claudius Lenz is a Researcher in the Department of Solar Materials at the Helmholtz Center for Environmental Research - UFZ, Leipzig, where he has been working since December 2022. His research is embedded within the Systems Biotechnology working group, focusing on the chemistry and biosynthesis of natural products, particularly from fungi. His research interests span natural product chemistry , fungal biotechnology , and the biochemistry of tryptamines such as psilocybin. He investigates oxidative dimerization, chromophore formation, and biosynthetic pathways in Psilocybe mushrooms, contributing to sustainable biotechnological production methods. The trends in his publications from 2017 to 2022 highlight a strong focus on the structural elucidation, bioactivity, and biosynthesis of psychoactive and pigmented fungal metabolites. His work bridges organic chemistry , biochemistry , and biotechnological applications , with implications for pharmaceutical development and green chemistry. Although no scientific awards are listed, his work has been published in high-impact journals such as Angewandte Chemie , Chemistry – A European Journal , and Journal of Natural Products . He completed his PhD in Natural Product Chemistry at the Leibniz Institute for Natural Product Research and Infection Biology and Friedrich-Schiller-University of Jena between 2017 and 2021, working under the supervision of Prof. D. Hoffmeister. No information is available on students he may have advised or grants he has led. Claudius Lenz is part of a multidisciplinary research environment at UFZ, contributing to the broader mission of sustainable ecotechnologies and tapping into nature's potential for environmental and pharmaceutical innovation.

Jane Dysonمشاهده پروفایل

استاد

• Structural Biology
• Protein Biophysics
• Molecular Biology
• +۳ مورد دیگر

Professor Jane Dyson is a distinguished academic at The Scripps Research Institute (TSRI), holding the position of Professor in the Department of Integrative Structural and Computational Biology since 2013. Her research focuses on structural biology, protein dynamics, and the role of intrinsic disorder in protein function, utilizing NMR spectroscopy as a primary tool. She has contributed extensively to understanding unfolded proteins, molecular chaperones, and transcription factor interactions, particularly in NF-κB signaling pathways and HPV oncogenesis. Education: B.S. (Biochemistry) and Ph.D. (Inorganic Chemistry) from the University of Sydney (1973, 1977), followed by a D.S. (Faculty of Science) in 2009. Professional experience includes postdoctoral roles at MIT and TSRI, progressing through academic ranks to full professorship. Research interests span NMR studies of disordered proteins, molecular machines, and chaperone-client interactions. Key contributions include elucidating NF-κB signaling mechanisms and defining structural principles of intrinsically disordered proteins. Over 200 publications highlight her work in structural biology, protein dynamics, and molecular recognition. Awards include the ISMAR Prize (2019), National Academy of Sciences membership (2022), and the D.Sc. Distinguished Scientist Award (2010). Her lab’s research bridges biochemistry, physics, and medicine, with ongoing studies on protein folding landscapes and functional disorder.

Alexander V. Rubanمشاهده پروفایل

استاد

• Biophysics
• Photosynthesis
• Photoprotection
• +۵ مورد دیگر

Professor Alexander V. Ruban is a Professor of Biophysics in the Department of Cell and Molecular Biology at Queen Mary University of London. He holds a 'Professeur des Universites' title from the French Ministry of Education and obtained his PhD from the Institute of Plant Physiology, Ukraine. His research focuses on the molecular mechanisms of photoprotection and light energy utilization in photosynthetic organisms, particularly the dynamics of the thylakoid membrane and LHCII antenna complexes. Affiliations: School of Biological and Chemical Sciences, Department of Cell and Molecular Biology Key Research Areas: Photosynthesis, Photoprotection, Biophysics, Light Harvesting Antennas Education: PhD in Plant Physiology from the Institute of Plant Physiology, Ukrainian Academy of Sciences. Research Interests: Ruban's work has elucidated the role of LHCII aggregation in photoprotection (NPQ), the structural and functional impact of xanthophylls, and the design principles of photosynthetic membranes. His lab employs techniques like picosecond fluorimetry and AFM to study membrane dynamics and protein interactions. Recent Articles Highlight: Ruban's research includes studies on the molecular mechanisms of NPQ, the role of lipid composition in energy dissipation, and the structural basis of light harvesting in diverse organisms like diatoms and algae. Awards: Royal Society Wolfson Research Merit Award (2020s), Fellow of The Royal Society of Biology. Grants & Collaborations: Leverhulme Trust grants on photosynthetic membrane structures and collaborations with institutions like the University of Sheffield and the Free University, Amsterdam. Labs/Teams: The Ruban Lab is part of the London Photosynthesis Network and engages in industrial partnerships (e.g., Valoya, Microsoft) for LED-based plant illumination systems.

• Organic Chemistry
• Natural Product Synthesis
• Biomimetic Synthesis
• +۳ مورد دیگر

Associate Professor Jonathan George is affiliated with the University of Adelaide, specifically within the Department of Chemistry. His research focuses on organic chemistry with an emphasis on natural product synthesis, particularly meroterpenoids and bioinspired total synthesis strategies. He leads the George Group, conducting investigations into complex molecule construction using biomimetic approaches. His work includes structural revisions of natural products and developing synthetic methodologies that mirror biological processes. Recent research highlights include studies on hyperireflexolides, erectones, and napyradiomycins, leveraging advanced techniques like vanadium-dependent haloperoxidase mimicry and diazo-Hooker reactions. His contributions span publications in organic synthesis, enzymology, and spectroscopic analysis, demonstrating expertise in both laboratory synthesis and computational methods. Dr. George's publications reflect a strong commitment to bridging synthetic organic chemistry with biological insights, addressing challenges in anticancer agents and antibiotic discovery. His lab actively explores radical chemistry, photochemical reactions, and structure-activity relationships in natural products.

Mélanie Hamonمشاهده پروفایل

پژوهشگر

• Host-Pathogen Interactions
• Epigenetics
• Innate Immunity
• +۴ مورد دیگر

Mélanie Hamon is a Structure Manager at the Pasteur Institute leading the Chromatin and Infection research team within the Cell Biology and Infection department. Her work focuses on epigenetic mechanisms in host-pathogen interactions , particularly studying Listeria monocytogenes and Streptococcus pneumoniae infection models. 2024 Chair of Excellence awardee 2024 publication on S. pneumoniae epigenetic memory 2024 discovery of host-directed oxadiazole compounds for tuberculosis Her research explores how: Bacterial pathogens modify chromatin to manipulate host transcription Epigenetic immune memory develops after infections Host metabolic pathways support pathogen replication Membrane dynamics facilitate intracellular niche formation Post-translational histone modifications affect infection outcomes Key methodologies include ChIP-seq , CRISPR , and mass spectrometry , with recent publications (2024) showing: Epithelial cell memory mechanisms Zinc poisoning in host-directed therapy SNX8-RAB11A axis in vacuole rupture Collagen induction via plasma activation Scientific contributions include: Discovered SIRT2-TDP-43 interaction in 2021 Identified IAM subpopulation dynamics in 2024 Elucidated KDM6B's role in 2021 Current advisees: PhD student: Justine Matheau PhD student: Leonardo Gonzalez-Smith

Charles Hanifinمشاهده پروفایل

استاد

• Evolutionary genetics
• Toxins
• Evolutionary ecology
• +۴ مورد دیگر

Charles Hanifin is a Professor in the Department of Biology at Utah State University's Uintah Basin campus in Vernal, Utah, where he teaches undergraduate courses including General Biology, Evolution, Genetics, and Physiology. A USU alumnus (PhD 2005), he maintains active research and teaching roles as evidenced by Fall 2024 course listings. Education: PhD in Biology (Ecology), Utah State University, 2005 BA in Biology, University of Chicago, 1991 Research Focus: Dr. Hanifin investigates evolutionary genetics of toxin resistance , particularly tetrodotoxin (TTX) dynamics in newt-predator arms races. His work integrates molecular biology , field ecology , and computational modeling to examine voltage-gated sodium channel adaptations across diverse taxa including newts, octopuses, and snakes. Recent studies (2022) employ in silico analysis to decode toxin-channel binding mechanisms. Publication Trends: His 15-year publication record (2008-2022) demonstrates consistent focus on TTX resistance evolution, with increasing computational approaches in recent work. Collaborations with Geffeney, Brodie, and Stokes dominate his output, revealing cross-taxon patterns in sodium channel adaptation. Key themes include convergent evolution mechanisms, geographic variation in toxicity, and novel toxin discoveries in terrestrial invertebrates. Awards: Utah State University Uintah Basin Research of the Year (2016) Undergraduate Research and Creative Opportunity Award (2013) Mentorship & Grants: Dr. Hanifin mentors graduate students (e.g., Kristopher Pedersen, 2018) and supervises undergraduate research through BIOL 5800. His 2013 award reflects success in developing Course-Based Undergraduate Research Experiences (CUREs), particularly for students at the Uintah Basin campus. Teaching records show sustained commitment to evolutionary biology education since 2012. Research Context: Based at USU's Vernal campus, his work leverages regional ecosystems for field studies of Taricha newts while collaborating with national experts on molecular analyses. The BEERC facility supports his integrated lab-field investigations of coevolutionary dynamics.

Dora Yuمشاهده پروفایل

پژوهشگر ارشد

• Structural Biology
• Cryo-EM
• Protein Structure
• +۳ مورد دیگر

Dora Yu is a Post-Doctoral Research Associate (PDRA) at the electron Bio-Imaging Centre (eBIC) at Diamond Light Source, having joined in October 2024. She works on the androgen receptor antagonist project under the supervision of Dr. Peijun Zhang within the eBIC research facility. Education PhD in Cell and Molecular Biology, Chinese University of Hong Kong: Her doctoral research focused on reconstituting and solving the protein structure of small heat shock proteins with substrates using cryogenic electron microscopy (cryo-EM), revealing novel anti-aggregation mechanisms. She additionally gained expertise in structural studies of membrane proteins during this period. Research Interests Dora specializes in high-resolution structural biology using cryo-EM to investigate protein conformational dynamics and molecular interactions. Her work bridges biophysics and biochemistry, with primary focus on heat shock protein mechanisms, membrane protein architecture, and nuclear receptor antagonism. She integrates biochemical reconstitution with advanced imaging to elucidate structure-function relationships in protein aggregation pathways and receptor-ligand interactions, contributing to therapeutic development for protein-misfolding disorders and hormone-related pathologies. Laboratory and Team As part of Dr. Peijun Zhang's research group at eBIC, Dora contributes to Diamond Light Source's world-leading cryo-EM facility which provides cutting-edge instrumentation for biological macromolecular imaging. The eBIC team operates multiple high-end electron microscopes and supports international researchers in structural biology projects. Contact Email: dora.yu@diamond.ac.uk Phone: +44 (0) 1235 77 8991

Miguel Adrover Estelrichمشاهده پروفایل

مدرس

• Physical Chemistry
• Protein Glycation
• Neurodegeneration
• +۷ مورد دیگر

Dr. Miguel Adrover Estelrich is a Lecturer in the Department of Chemistry at the University of the Balearic Islands (UIB), where he has been an active faculty member since 2006. He is based in the Mateu Orfila i Rotger (Chemistry) building and teaches courses such as Physical Chemistry III, Chemistry of Biological Macromolecules, and Experimentation in Biological Chemistry across undergraduate and postgraduate programs. Graduated in Chemical Sciences, UIB (2003) PhD in Chemistry, UIB (2008) Postdoctoral Research, National Institute for Medical Research, London (2009–2010) His research focuses on protein glycation and its role in neurodegeneration in diabetic patients . He uses techniques such as NMR spectroscopy to study protein structure, aggregation, and denaturation. His early work involved kinetic studies of vitamin B6 derivatives and carbohydrates as inhibitors of glycation. The trends in his research, reflected across his publications, emphasize molecular mechanisms of disease , protein misfolding , and structural biochemistry . His work bridges physical chemistry and biomedical applications , particularly in diabetes and neurodegenerative disorders. Dr. Adrover has achieved 3 six-year research evaluations and 3 five-year teaching evaluations , indicating sustained excellence in both domains. He has directed 2 PhD theses, 13 Master's projects, and 5 Final Degree projects, demonstrating strong mentorship. Member, Interdisciplinary Group on Neurodegeneration, Vascular and Metabolic Diseases (INNoVAM) Participated in 30 research projects Published 58 JCR-indexed articles (h-index: 20, 1073 citations) Holds a granted patent He continues active research and teaching at UIB, contributing to both education and scientific understanding of metabolic and neurodegenerative diseases.

Anthony Ivan Dayمشاهده پروفایل

استاد

• Organic Chemistry
• Synthetic Chemistry
• Supramolecular Chemistry
• +۴ مورد دیگر

Dr. Anthony Ivan Day is a distinguished researcher at UNSW Canberra, affiliated with the School of Physical, Environmental and Mathematical Sciences. He maintains an active research program focused on supramolecular chemistry and macrocyclic systems, with his laboratory located in Room 220 PEMS North (Building 22) at the Australian Defence Force Academy campus. His research expertise spans organic chemistry, synthetic design, and the development of new synthetic techniques, with specific focus areas in Inorganic Chemistry, Organic Chemistry, Medicinal and Biomolecular Chemistry, and Nanochemistry and Supramolecular Chemistry. Day is recognized as a principal developer of the cucurbit[n]uril family of macrocyclic host molecules, holding international patents for both the original compounds and their derivatives. His publication record includes 74 journal articles, 2 book chapters, 6 conference papers, 1 conference presentation, 9 theses/dissertations, and 1 patent. Current research emphasizes applications of cucurbit[n]uril in drug delivery systems, with particular interest in developing pharmaceutical applications through synthetic chemistry approaches. International patents as inventor of cucurbit[n]uril family International patents on cucurbit[n]uril derivatives Dr. Day offers PhD scholarship opportunities ($35,000 per year) for high-achieving students with First Class Honors or equivalent qualifications in Chemistry. His research continues to explore innovative synthetic methods for preparing cucurbit[n]uril derivatives to extend applications in drug delivery and other fields.

Amila Agampodi Dewaمشاهده پروفایل

عضو هیئت علمی

• Natural Products Chemistry
• Medicinal Chemistry
• Microbial Biodiversity
• +۳ مورد دیگر

Dr Amila Agampodi Dewa is a Postdoctoral Research Fellow at the Institute for Molecular Bioscience (IMB), The University of Queensland. Her work focuses on exploring microbial biodiversity to discover novel natural products with medicinal applications. She specializes in isolating and characterizing bioactive compounds from marine and terrestrial fungi, particularly those with anti-viral, anti-cancer, and anti-microbial properties. Education: PhD in Natural Products Chemistry, The University of Queensland (2022) Bachelor (Honours) of Pharmaceutical Sciences, University of Colombo Research Interests: Dr Dewa's research integrates chemical ecology, microbial genomics, and drug discovery. She investigates fungal secondary metabolites, focusing on compounds that modulate drug resistance mechanisms (e.g., P-glycoprotein inhibitors) and employs precursor-directed biosynthesis to amplify production of rare metabolites. Her work bridges marine biology and medicinal chemistry, leveraging underexplored environments like termite nests and marine fish-derived fungi. Publications: Her recent studies highlight discoveries of novel glycosides (e.g., Liriosmaside A), triterpene aminoglycosides (Pullenvalenes), and phenylpropanoid piperazines with therapeutic potential. These findings advance understanding of natural product biosynthesis pathways and their applications in drug development. Affiliations: IMB's interdisciplinary environment supports her collaborations in microbial biodiversity, chemical ecology, and translational research. She is available for PhD supervision in natural products chemistry and drug discovery.