جست‌وجوی استاد و پژوهشگر

• Cancer Cell Metastasis
• Tumor Microenvironment
• Focal Adhesion Signaling
• +۴ مورد دیگر

Vasiliki Gkretsi is an Associate Professor at the School of Sciences, European University Cyprus, Department of Life Sciences. She holds a Ph.D. in Cellular and Molecular Pathology from the University of Pittsburgh (2006) and a Diploma in Biology from the National and Kapodistrian University of Athens (2001). Her research focuses on cancer metastasis mechanisms, particularly the role of focal adhesion proteins like ILK, RSU-1, and GDF-15 in tumor progression. She has held academic roles including Assistant Professor (2017–2020) and Senior Scientist (2015–2017) at the University of Cyprus and University of Thessaly’s biomedical research institutes. Her work integrates bioengineering approaches with molecular biology to study tumor microenvironment dynamics, cell adhesion signaling, and metastatic processes. Key contributions include identifying RSU-1 as a dual-function regulator in breast and glioma cancers and exploring GDF-15’s role in metastasis. She has led projects funded by the European Society for the Study of the Liver (EASL Sheila Sherlock Fellowship) and the Research Promotion Foundation. Education: Ph.D., Cellular and Molecular Pathology, University of Pittsburgh (2006) Diploma in Biology, National and Kapodistrian University of Athens (2001) Awards: EASL Sheila Sherlock Fellowship (2012–2014) Stephen L. Phillips Scientific Achievement Award (2005) Roles: Special Issue Editor, International Journal of Molecular Sciences and Life Member of Bioethics Evaluation Committee for Biomedical Research Her research spans over 45 peer-reviewed articles and has been cited over 1,600 times (Google Scholar). She holds a provisional U.S. patent for anti-inflammatory methods targeting the actin cytoskeleton.

Sarah E. Hallمشاهده پروفایل

دانشیار

• Epigenetics
• Developmental Biology
• RNA Interference
• +۴ مورد دیگر

Sarah E. Hall is an Associate Professor in the Department of Biology within the College of Arts and Sciences at Syracuse University with joint affiliation in Biochemistry and Biotechnology. Her research investigates epigenetic mechanisms linking early environmental experiences to adult phenotypic changes using C. elegans as a model organism. Education: Ph.D. in Genetics, University of Chicago (2004) B.S. in Biochemistry and Genetics, Texas A&M University (1998) Her work centers on how endogenous RNAi pathways regulate gene expression and chromatin states in response to developmental and environmental stressors like starvation, with implications for metabolic and mental disorders. She employs genetic, imaging, and molecular techniques to study transgenerational inheritance of stress responses and reproductive plasticity. Analysis of her recent publications reveals a cohesive research trajectory focused on RNA-mediated epigenetic regulation in C. elegans , spanning neurobiology, stress inheritance, and aging. Her work consistently bridges molecular genetics with organismal physiology, emphasizing conserved mechanisms relevant to human disease. Grants and Advising: Dr. Hall directs an active research program funded by an NIH R01 grant (2019-2025) and a CUSE Innovation Grant (2018-2023). She mentors graduate students who regularly present at national conferences including Genetics Society of America meetings, and teaches core courses in genetics and graduate research. She leads the WormLab (https://wormlab.syr.edu/), which integrates molecular biology and bioinformatics to dissect environmental programming mechanisms within Syracuse University's neuroscience and epigenetics research communities.

Jamie H. D. Cateمشاهده پروفایل

استاد

• Biochemistry
• Biophysics
• Structural Biology
• +۷ مورد دیگر

Jamie H. D. Cate is a Professor of Biochemistry, Biophysics and Structural Biology, and Chemistry at the University of California, Berkeley. He leads the Cate Lab, focusing on understanding protein synthesis mechanisms, particularly through the study of ribosomes and their roles in translation regulation. His work also involves engineering ribosomes to synthesize novel polymers, contributing to the Center for Genetically Encoded Materials (C-GEM). His research explores how genes are translated into proteins, specifically investigating the ribosome's role in this universal process. Key areas include understanding translation initiation regulation by eIF3, its role in cancer-related mRNA regulation, and viral hijacking mechanisms. Additionally, he pioneers methods to engineer ribosomes for producing non-natural polymers using mRNA templates. Techniques employed include cryo-electron microscopy, biochemistry, and systems biology. Recent studies highlight the lab's focus on eIF3's dual role in activating and repressing specific mRNAs, particularly in T cells and neural progenitor cells. The lab also investigates ribosome structural adaptations to incorporate non-canonical amino acids and the molecular basis of drug-induced ribosome stalling. These efforts aim to advance therapeutic strategies and synthetic biology applications. Lab affiliations: Cate Lab at UC Berkeley, part of the Department of Biochemistry, Biophysics, and Structural Biology, and the Center for Genetically Encoded Materials (C-GEM). No notable scientific awards are listed in the provided texts. Advising information and grant details are not explicitly mentioned here.

Alanna Schepartzمشاهده پروفایل

استاد

• Chemical Biology
• Synthetic Biology
• Biosynthesis of Polymers
• +۴ مورد دیگر

Alanna Schepartz is the CZ and Irmgard Distinguished Chair of Chemistry and Professor of Molecular Therapeutics at UC Berkeley's Department of Molecular and Cell Biology, within the College of Letters & Science. Her research spans chemical biology and synthetic biology, focusing on repurposing cellular machinery for novel applications. Current projects include ribosome engineering for polymer synthesis, CPMP-mediated protein delivery, EGFR membrane signaling, and HIDE probes for super-resolution imaging. The Schepartz Lab collaborates widely, including with the NSF Center for Genetically Encoded Materials (C-GEM). Notable tools developed include HIDE probes for organelle visualization and CPMPs for therapeutic delivery. Recent work highlights advancements in genetic code expansion, endosomal escape mechanisms, and organelle dynamics imaging. Education details are not explicitly listed, but her academic standing and leadership roles imply advanced training in chemistry/biochemistry. She advises graduate and undergraduate students, including recent graduates Lauren Lesiak, Angel Vazquez Maldonado, and others. Collaborations involve institutions like Yale University and Penn State, with ongoing efforts in NIH/NSF-funded projects. Future directions include expanding HIDE probe capabilities, optimizing CPMP delivery systems, and exploring allosteric signaling pathways in kinases. Research Themes: Ribosome repurposing, protein delivery, membrane signaling, organelle imaging Key Tools: HIDE probes, CPMPs, genetic code expansion platforms Collaborative Networks: NSF C-GEM, Yale Cell Biology Group

• Biophysics
• Soft Matter
• Nanoscience
• +۴ مورد دیگر

Dr. Stefano Da Vela is a Postdoctoral Researcher at the Alfred Wegener Institute (AWI), affiliated with the Department of Ecological Chemistry. His research focuses on Biophysics, Soft Matter, and Nanoscience in marine, polar, and coastal contexts, with expertise in scattering methods like SAXS and SANS. He investigates structural properties of biomolecules, colloidal systems, and phase transitions in complex environments. Key research interests include nanoparticle characterization, protein aggregation mechanisms, and the development of biocompatible nanocarriers. His work integrates experimental techniques with computational modeling to understand molecular interactions in biological systems. Dr. Da Vela contributes to advancing methodologies for studying phase behavior in protein solutions and polymer systems. Recent publications highlight studies on micellar structures, prion protein-ligand interactions, and the structural dynamics of mitochondrial proteins. His interdisciplinary approach bridges materials science, biochemistry, and environmental contexts, particularly in polar and coastal ecosystems.

• Microbiology
• Molecular Biology
• Bacterial Resistance
• +۳ مورد دیگر

Hala Kasmo is a Researcher at the University of Namur, affiliated with the Namur Research Institute for Life Sciences and its Research Unit in Biology of Microorganisms . Her work focuses on bacterial metal resistance mechanisms, particularly copper tolerance in Caulobacter crescentus . Education: Master in Molecular Microbiology (2021) with a thesis on small RNA and oxygenase roles in copper tolerance. Research explores bidirectional copper transport, iron-dependent resistance pathways, and the function of TonB-dependent receptors in free-living bacteria. Active projects (2024–2025) investigate the CopA exporter and copper homeostasis. Her 2025 Journal of Bacteriology article highlights oxygenase and receptor interactions in metal resistance. Engaged in academic outreach, she participated in organizing the Women and Girls in Science conferences (2023–2024) at UNamur. Collaborations span molecular microbiology, environmental adaptation, and sustainable technologies aligning with UN SDGs.

• Immunology
• Inflammasome Biology
• Toll-like Receptors
• +۳ مورد دیگر

Brian Monks is an Instructor in the Department of Medicine at UMass Chan Medical School, affiliated with the T.H. Chan School of Medicine. He holds a BS and MS in Microbiology from the University of Massachusetts Amherst. His research focuses on innate immunity, particularly inflammasome biology and Toll-like receptor signaling, with contributions to understanding inflammation mechanisms and microbial pathogenesis. Monks has collaborated extensively with experts like Dr. Golenbock and Dr. Latz on projects involving NLRP3 inflammasome inhibitors, ASC speck formation, and TLR4 signaling pathways. Notable work includes studies on CRID3 inhibitors and fluorescent reporter systems for inflammasome activity. His publications span Science , Nature Immunology , and Journal of Immunology , addressing topics from amyloid-β immunology to malaria-induced innate responses.

Peter Vandenabeeleمشاهده پروفایل

پژوهشگر

• Cell Death Mechanisms
• Immunology
• Inflammation
• +۳ مورد دیگر

Peter Vandenabeele is a VIB Group Leader at Ghent University's Center for Inflammation Research since 1996. He holds a PhD from Ghent University (1990). His research focuses on molecular mechanisms of cell death modalities (apoptosis, necroptosis, ferroptosis) and their roles in immunology, cancer, and inflammatory diseases. His lab investigates signaling pathways involving caspases, RIPKs, and MLKL, using cellular and mouse models to explore therapeutic targets. Subgroups under his leadership (Bertrand, Declercq, Riquet) specialize in stress-induced cell death, skin inflammation, and dynamic imaging of cell death pathways. Key areas include drug screening for cell death modulation and translational research in oncology and neurodegeneration. His work has been featured in media like Knack and EOS Wetenschap, and he contributes to VIB's research initiatives such as the Marie Curie fellowship program. Education: PhD in Molecular Biology, Ghent University (1990). Research Interests: Cell death regulation, innate immunity, cancer therapy, signaling pathways. His lab's interdisciplinary approach spans biochemistry, genetics, and pharmacology, aiming to bridge fundamental discoveries with clinical applications in inflammation and cancer. Notable achievements include Clarivate Highly Cited Researcher recognition (2024) and contributions to international collaborations. The lab actively participates in grant programs (FWO, VIB) and maintains strong ties with industry through translational efforts.

Alex Bishopمشاهده پروفایل

دانشیار

• Ewing Sarcoma
• DNA Repair
• R-loops
• +۳ مورد دیگر

Dr. Alex Bishop is an Associate Professor in the Department of Cell Systems and Anatomy at The University of Texas Health San Antonio, within the Joe R. and Teresa Lozano Long School of Medicine. His research focuses on unraveling the molecular mechanisms underlying pediatric cancers, particularly Ewing sarcoma, with emphasis on R-loop regulation, DNA repair pathways, and oncogenic transcriptional dysregulation. Dr. Bishop holds a DPhil from Oxford University and completed further training at Harvard Medical School. He has led groundbreaking studies including identifying R-loop accumulation as a therapeutic target in Ewing sarcoma and discovering links between BRCA1 dysfunction and cancer progression. His work has been published in high-impact journals like Nature and supported by grants from Stand Up To Cancer and Cancer Research UK. Key research areas include understanding how the EWSR1-FLI1 fusion protein drives genomic instability, developing mouse models for sarcoma research, and advancing computational tools like RLSuite for R-loop analysis. Collaborations with institutions such as the Greehey Children’s Cancer Research Institute and Mays Cancer Center enable translational research bridging basic science and clinical applications. Dr. Bishop’s contributions have advanced targeted therapies for pediatric cancers, with recent efforts exploring combination treatments and novel biomarkers. His lab employs cutting-edge technologies including mass cytometry and single-cell transcriptomics to dissect tumor biology and resistance mechanisms.

Katarzyna Makasewiczمشاهده پروفایل

پژوهشگر

• Biophysics
• Biochemistry
• Nanotechnology
• +۳ مورد دیگر

Katarzyna Makasewicz is a Researcher at the Institute of Chemical Biology (ICB) at ETH Zurich, Switzerland, working under Prof. Paolo Arosio. Her research focuses on understanding biomolecular interactions, particularly protein-membrane dynamics and phase separation processes. She holds a B.Sc. (2016) and M.Sc. (2017) in Nanotechnology from Lodz University of Technology, Poland, where she specialized in polymeric nanoparticle synthesis using ionizing radiation. During her M.Sc., she conducted a research internship at the University of Palermo, Sicily. She completed her Ph.D. in Physical Chemistry at Lund University (Sweden, 2018–2022), studying α-synuclein’s role in lipid membrane interactions, supervised by Prof. Emma Sparr and Prof. Sara Linse. Her postdoctoral work at ETH Zurich investigates rheological properties of protein droplets and aging processes in biomolecular condensates. Her research interests span biophysics, biochemistry, and nanotechnology, with a focus on protein aggregation mechanisms, membrane remodelling, and the functional implications of biomolecular condensates. Techniques employed include microfluidics, small-angle scattering, and fluorescence microscopy. She has contributed to understanding how environmental factors modulate protein behavior in cellular contexts, with implications for neurodegenerative diseases and material science. Notable projects include analyzing α-synuclein’s cooperative binding to lipid vesicles and the formation of multi-compartment condensates through aging processes. Her work bridges fundamental biophysical studies with applications in nanomedicine and disease modeling.

• Plant Pathology
• Plant Immunity
• Phytophthora
• +۴ مورد دیگر

Klaas Bouwmeester is an EPS Assistant Professor in Biosystematics at Wageningen University & Research. His research focuses on plant-pathogen interactions, particularly in understanding mechanisms of plant immunity against oomycetes like Phytophthora and insects. He investigates defense signaling pathways, genetic resistance, and genomic diversity in crops such as Brassica species. Education: Not explicitly stated in provided texts, but his titles include dr.ir.ing., indicating academic qualifications in engineering and life sciences. His work integrates genomics, transcriptomics, and molecular biology to uncover how plants respond to pathogens and pests. Key projects include studying hypersensitive responses to butterfly eggs, co-evolution of immune genes, and decoding specialized metabolic pathways in plants. Bouwmeester has supervised multiple PhD candidates in plant defense mechanisms and collaborates on projects addressing crop resistance breeding. He has published over 98 research outputs, including studies on Phytophthora effector proteins, Brassica resistance loci, and omics-based approaches to plant metabolism. His research also involves creating novel pathosystems (e.g., Physcomitrella patens and Phytophthora ) to study cellular defense responses. Current projects include exploiting wild Brassica relatives for crop resistance and predicting meiotic recombination using machine learning. Bouwmeester’s work bridges fundamental research and applied plant breeding to enhance agricultural resilience.

• Aphid Biology
• Plant-Insect Interactions
• Transcriptomics
• +۳ مورد دیگر

Sampurna Sattar is an Assistant Teaching Professor in the Department of Biochemistry and Molecular Biology at Pennsylvania State University. Her research focuses on plant-insect interactions, specifically aphid biology and resistance mechanisms. She investigates molecular responses in plants and aphids using transcriptomics, miRNA regulation, and insecticidal proteins. Her work contributes to understanding aphid adaptation, plant defense mechanisms, and sustainable pest management strategies. Sattar is affiliated with Althouse Laboratory and has published extensively on topics such as aphid transcriptome analysis, nicotinamide's effects on aphids, and small RNA roles in plant defense. Her research interests span aphid physiology, chemical ecology, and molecular genetics. Key themes include identifying plant compounds conferring resistance (e.g., 3-deoxyanthocyanidin flavonoids), analyzing transcriptomic changes during host interactions, and characterizing novel insecticidal proteins from Bacillus thuringiensis. She also explores miRNA-mediated pathways regulating plant defense responses against aphid herbivory. Notable contributions include studies on Vat-mediated resistance mechanisms in melon plants, which involve miRNA repression of auxin signaling pathways. Her work bridges fundamental molecular biology with applied agricultural challenges, emphasizing sustainable pest control solutions. No scientific awards or grants are explicitly listed in the provided information. She advises no students in the available data but contributes to teaching and research in biochemistry and molecular biology.

• Biochemistry
• Enzymology
• Metabolic Pathways
• +۳ مورد دیگر

Douglas Warui is an Associate Research Professor in the Department of Chemistry at Pennsylvania State University. His research focuses on enzymology, biochemistry, and metabolic pathways, with particular emphasis on protein interactions and catalytic mechanisms. His work includes studies on lipoylation pathways, mitochondrial ferredoxins, and hydrogenase maturation processes. He has also contributed to understanding fatty acid conversion mechanisms and enzymatic oxygenation reactions. Warui's research integrates structural biology, enzymology, and biotechnology to explore topics such as copper-dependent cell death mechanisms, enzyme substrate delivery systems, and catalytic intermediates. His recent work has highlighted the role of lipoyl-H-protein in DTMA ligand biosynthesis and the functional specificity of mitochondrial ferredoxins FDX1 and FDX2. He has also investigated the biochemical pathways involved in converting fatty acids into biofuels through aldehyde deformylating oxygenase systems. His publications span a decade of contributions to enzymology, with a focus on redox reactions, oxygenases, and protein engineering. While no formal awards are cited here, his prolific publication record reflects significant scholarly impact in biochemistry and biotechnology. Warui collaborates on projects involving protein-ligand interactions and has explored small molecule inhibitors targeting HIV-1 RNA complexes. His research often employs in vitro systems to dissect catalytic processes and protein interactions, contributing to both fundamental understanding and potential biotechnological applications.

Ling Chenمشاهده پروفایل

پژوهشگر

• Plant Biology
• Molecular Biology
• Genetics
• +۳ مورد دیگر

Ling Chen is a Postdoctoral Researcher affiliated with the Bevilacqua Lab at Pennsylvania State University. Their research focuses on plant immunity mechanisms, molecular genetics, and protein function in biological systems. Research interests include plant-pathogen interactions, RNA processing pathways, and the regulation of developmental processes such as flowering time. They investigate how proteins like SKRP and UBA2c influence immunity and gene expression, with applications to crop protection and basic plant biology. Key contributions include studies on small G-proteins in disease resistance and the structural characterization of galectins in insects. Their work bridges molecular biology with evolutionary genetics, particularly in understanding host-pathogen co-evolution through effector proteins. No academic awards or grants are explicitly listed in the provided information.

• Genomic stability
• DNA repair
• Cancer biology
• +۵ مورد دیگر

Dr. Amila Suraweera is a Research Fellow and Visiting Fellow at the Queensland University of Technology (QUT), affiliated with the Faculty of Health and School of Biomedical Sciences. She holds a PhD in Molecular Biology and Biochemistry from the University of Queensland (2008) and a BSc (Honors) from the University of New South Wales (2002). Her research focuses on genomic stability, DNA repair mechanisms, and their implications in cancer biology, particularly lung cancer and drug discovery. Dr. Suraweera’s work explores pathways dysregulated in cancers, with a focus on proteins like COMMD4, Banf1, and Aldolase A, which influence DNA repair processes and therapeutic responses. Her research interests include epigenetic therapy, targeted drug development, and the interplay between cellular metabolism and DNA repair. She has contributed to understanding the role of proteins like COMMD4 in lung cancer prognosis and therapy, as well as mechanisms regulating DNA double-strand break repair pathways. Dr. Suraweera has published extensively on topics such as epigenetic drugs in cancer therapy, protein complexes involved in DNA repair, and the metabolic regulation of repair processes. Her articles highlight advancements in lung cancer treatment strategies, including targeting COMMD4-H2B complexes and leveraging Aldolase A for DNA repair modulation. Recent work emphasizes the clinical relevance of epigenetic mechanisms and drug sensitivity in cancer therapy. Dr. Suraweera collaborates with institutions like the MRC Laboratory of Molecular Biology and maintains affiliations with multiple research programs in cancer genomics and personalized health. While no formal awards are listed, her contributions to cancer research are evident through her publications and collaborative projects. Her research has implications for developing novel therapeutic approaches and biomarkers in oncology.