معرفی
Alanna Schepartz is the CZ and Irmgard Distinguished Chair of Chemistry and Professor of Molecular Therapeutics at UC Berkeley's Department of Molecular and Cell Biology, within the College of Letters & Science. Her research spans chemical biology and synthetic biology, focusing on repurposing cellular machinery for novel applications. Current projects include ribosome engineering for polymer synthesis, CPMP-mediated protein delivery, EGFR membrane signaling, and HIDE probes for super-resolution imaging. The Schepartz Lab collaborates widely, including with the NSF Center for Genetically Encoded Materials (C-GEM). Notable tools developed include HIDE probes for organelle visualization and CPMPs for therapeutic delivery. Recent work highlights advancements in genetic code expansion, endosomal escape mechanisms, and organelle dynamics imaging.
Education details are not explicitly listed, but her academic standing and leadership roles imply advanced training in chemistry/biochemistry. She advises graduate and undergraduate students, including recent graduates Lauren Lesiak, Angel Vazquez Maldonado, and others. Collaborations involve institutions like Yale University and Penn State, with ongoing efforts in NIH/NSF-funded projects. Future directions include expanding HIDE probe capabilities, optimizing CPMP delivery systems, and exploring allosteric signaling pathways in kinases.
- Research Themes: Ribosome repurposing, protein delivery, membrane signaling, organelle imaging
- Key Tools: HIDE probes, CPMPs, genetic code expansion platforms
- Collaborative Networks: NSF C-GEM, Yale Cell Biology Group
