معرفی
Dr. Maximilian Fottner is a Lecturer at the Department of Chemistry and Applied Biosciences at ETH Zürich, affiliated with the Laboratory of Organic Chemistry (LOC). His research focuses on chemical biology, protein biochemistry, and genetic code expansion techniques, particularly exploring ubiquitin signaling, posttranslational modifications, and protein engineering. He develops innovative tools for protein labeling, conjugation, and functionalization, with applications in cellular signaling, proteostasis, and therapeutic design. His work bridges biochemistry, nanotechnology, and molecular biology to address fundamental questions in protein function and disease mechanisms.
Recent research highlights include studies on ubiquitin-proteasome system dynamics, genetic code expansion for deciphering the ubiquitin code, and site-specific protein modifications using sortase enzymes. Fottner's lab also investigates protein-membrane interactions and the role of intestinal myofibroblasts in epithelial cell plasticity. He collaborates on projects involving magnetic nanoparticle-based enzyme immobilization and integrin-targeted tumor imaging agents.
His teaching includes courses like 'Genetic Code Expansion for Studying Posttranslational Modifications' and 'Chemical Biology and Synthetic Biochemistry.' Fottner's contributions span from foundational biochemical studies to translational applications in biotechnology and medicine.
