جست‌وجوی استاد و پژوهشگر

Michael Lukeyمشاهده پروفایل

دانشیار

• Cancer Metabolism
• Tumor Microenvironment
• Metabolic Adaptation
• +۲ مورد دیگر

Michael Lukey is an Associate Professor at Cold Spring Harbor Laboratory and Assistant Director of Shared Resources at the Cancer Center. His research investigates metabolic adaptations in cancer, focusing on nutrient utilization, redox homeostasis, and therapeutic vulnerabilities across tumor microenvironments. Education includes a Ph.D. from University of Oxford (2010) and postdoctoral training at Cornell University. Major research themes include glutamine metabolism, metabolic rewiring in glioblastoma, and ketogenic diet effects on tumor progression. Recent publications demonstrate innovations in targeting metabolic enzymes like PSAT1 and glutaminases, with applications in viral pathogenesis and cancer therapy. Awards include the METAvivor Early Career Investigator Award and Breast Cancer Coalition Research Award. Professional activities involve conference presentations on cancer metabolism topics and curriculum development for chemistry of signal transduction courses. Research integrates biochemical, genetic, and therapeutic approaches to combat tumor metabolic adaptations.

Joel Neilsonمشاهده پروفایل

دانشیار

• Molecular Biology and Genetics
• Cell and Developmental Biology
• Post-Transcriptional Regulation of Gene Expression
• +۱ مورد دیگر

Joel Neilson, Ph.D. is an Associate Professor at Baylor College of Medicine , affiliated with the Graduate School of Biomedical Sciences and the Dan L Duncan Comprehensive Cancer Center . His research focuses on post-transcriptional gene regulation in mammalian development and disease. Education: BS (University of Washington), Ph.D. (Stanford University School of Medicine), Postdoctoral Training (Massachusetts Institute of Technology) Research Interests center on post-transcriptional regulation via microRNAs and RNA-binding proteins, particularly their roles in human disease, cancer, and developmental biology. The lab employs high-throughput sequencing, molecular genetics, and mouse models to study 3' UTR interactions and gene expression control. Publication Trends highlight expertise in Epithelial-Mesenchymal Transition (EMT) , Ribosomopathies , Stress Granules , and Cancer Metabolism , with recent work linking telomere dysfunction to sirtuin repression and exploring HIV-1 vaccine modeling. Labs & Collaborations: Neilson Lab at Baylor College of Medicine Technical Expertise: Ribosomal Profiling, Mouse Mutant Models, Advanced Technology Core Laboratories

Ergun Sahinمشاهده پروفایل

دانشیار

• Telomere Biology
• Cancer Biology
• Aging Research
• +۳ مورد دیگر

Ergun Sahin, M.D., Ph.D., is an Associate Professor at Baylor College of Medicine, based at the Huffington Center on Aging. He holds expertise in telomere biology, cancer, and aging mechanisms. His research focuses on telomere shortening-induced pathologies, mitochondrial dysfunction, and metabolic pathways linked to aging and cancer. Sahin obtained his M.D. and Ph.D. from the Free University of Berlin and completed postdoctoral training at Dana-Farber Cancer Institute. His work integrates molecular biology, genetics, and translational research to address fundamental questions in telomere biology and oncology. **Education**: M.D., Free University of Berlin (1998) Ph.D., Free University of Berlin (2002) Post-Doctoral Fellowship, Dana-Farber Cancer Institute (2011) **Research Interests**: Role of telomeres in cancer and aging Mitochondrial dysfunction in aging tissues Epigenetic regulation of telomerase in tumors Microbiome interactions in telomere-driven colitis Therapeutic targeting of telomerase-dependent pathways **Key Findings**: Discovered mechanisms linking telomere attrition to metabolic decline and mitochondrial impairment Elucidated telomerase's role in reversing aging-associated cellular deficits Identified novel therapeutic vulnerabilities in cancer via passenger deletions **Labs/Teams**: Active in translational research teams at Baylor College of Medicine, focusing on aging-related diseases and oncology drug development.

Jens Vanselowمشاهده پروفایل

مدرس

• Reproductive Biology
• Folliculogenesis
• Luteinization
• +۵ مورد دیگر

Jens Vanselow is a Lecturer at the University of Rostock and currently serves as the Head of Competence area Reproduction and Development and Head of Working group Cell Physiology & Reproduction at the Research Institute for Farm Animal Biology (FBN) in Dummerstorf, Germany. He holds a PhD (Dr. rer. nat.) from Eberhard Karls University Tübingen and a habilitation from the University of Rostock. Affiliations: Research Institute for Farm Animal Biology (FBN), University of Rostock Roles: Leader of research groups in reproductive biology and cell physiology His research focuses on Reproductive Biology , including folliculogenesis, luteinization, spermatogenesis, gene regulation, and epigenetics. He has contributed significantly to understanding the molecular mechanisms underlying ovarian and testicular functions, particularly in farm animals. Teaching: He teaches courses such as 'Molecular Biology of the Cell' and 'Reproduction and Reproductive Biotechnology' at the University of Rostock, spanning both biosciences and agricultural sciences. Labs/Teams: Leads the Cell Physiology & Reproduction group at FBN, focusing on cellular and molecular aspects of reproductive processes.

Hemanga Gogoiمشاهده پروفایل

پژوهشگر ارشد

• Structural Biology
• Chromatin Biology
• Molecular Biology
• +۳ مورد دیگر

Hemanga Gogoi is a Doctoral Research Fellow at the University of Oslo (UiO), affiliated with the Faculty of Mathematics and Natural Sciences. He is part of the Nikolina Sekulic Group specializing in Structural Biology and Chromatin. His research focuses on understanding molecular mechanisms of proteins, particularly in the context of structural biology, enzymology, and their roles in diseases such as cancer and neurodegenerative disorders. He holds a PhD and has contributed to high-impact studies on protein structure-function relationships. Contact: hemanga.gogoi@ncmbm.uio.no Research interests include structural biology of kinases, chromatin dynamics, and computational approaches to drug discovery. His work bridges biochemical experiments and structural analyses to elucidate mechanisms underlying cellular processes. Publications highlight contributions to understanding Aurora B kinase activation, sirtuin-6 modulators, and α-synuclein interactions. His recent work (2024) explores Tau phosphorylation’s role in neurodegenerative diseases. No academic awards or grants are explicitly mentioned. He collaborates in the Sekulic Group, contributing to interdisciplinary projects at the intersection of biochemistry and structural biology.

Mustafaمشاهده پروفایل

استاد مدعو

• Cultural Anthropology
• Biological Anthropology
• Religious Studies
• +۵ مورد دیگر

Mentor Mustafa is an Adjunct Professor in the Department of Anthropology at Boston University's Metropolitan College. He holds a Ph.D. in Cultural Anthropology (2015), an M.A. in Biological Anthropology (2002), an M.Ed. in Higher Education Pedagogy (2006), and a B.A. in Archaeological Science (1999). His research spans cultural anthropology (religion and post-communist revival in Southeastern Europe) and biological anthropology (hunter-gatherer prehistory, stone tool technology, and human evolution). He teaches courses in human biology, cultural studies, and religious anthropology. His interdisciplinary work bridges anthropology with biomedical research, as evidenced by publications on vascular biology, diabetes complications, and neurotoxicology. He has contributed to studies on endothelial dysfunction, microRNA regulation in disease, and nanoparticle-induced neurotoxicity. Mustafa emphasizes innovative teaching strategies to enhance student engagement in higher education. Notable research themes include: Religious revival dynamics in post-communist Albania Stone tool technology and human evolution Endothelial cell dysfunction in diabetes and e-cigarette use Neurological effects of aluminum and silica nanoparticles His recent biomedical research focuses on vascular biology, diabetes-associated pathologies, and molecular mechanisms of cellular stress. This includes investigations into miRNA regulation, oxidative stress pathways, and protein modification dynamics in disease contexts.

• Cancer Biology
• Pharmacology
• Molecular Biology
• +۳ مورد دیگر

Mary E. Law is a Research Assistant Professor in the Department of Pharmacology and Therapeutics at the University of Florida. Her research focuses on cancer biology, pharmacology, and molecular mechanisms of disease, with an emphasis on drug development targeting protein folding stress pathways, ER stress, and apoptosis regulation. She has contributed to studies on anticancer agents, including disulfide-bond disrupting compounds and repurposed drugs like tranexamic acid. Dr. Law has taught numerous courses since 2009, including Medical Pharmacology, Principles of Drug Action, and Cell Signaling, reflecting her expertise in therapeutic strategies and drug mechanisms. Her grants include projects on targeting HER receptors and death receptors in breast cancer, as well as reducing racial disparities in cancer outcomes through synthetic-lethal strategies. Her work spans experimental therapeutics, molecular biology, and translational research, with over 40 publications in high-impact journals. Key areas include protein disulfide isomerases as therapeutic targets, mechanisms of drug resistance, and the unfolded protein response in cancer.

• Cardiovascular Biology
• Redox Signaling
• Endothelial Dysfunction
• +۷ مورد دیگر

Dr. Hua Cai is a Professor in the Departments of Anesthesiology and Medicine at the University of California, Los Angeles (UCLA) School of Medicine. Her research focuses on cardiovascular biology, redox signaling, and endothelial dysfunction, with particular emphasis on oxidative stress mechanisms in atherosclerosis, hypertension, and diabetes complications. Her research interests include: Cardiovascular Biology Redox Signaling Endothelial Dysfunction Atherosclerosis Hypertension Diabetes Complications Pulmonary Hypertension Aortic Aneurysm e-Cigarette Toxicity Vascular Inflammation She investigates NADPH oxidases (NOX) and tetrahydrobiopterin (BH4) in endothelial nitric oxide synthase (eNOS) uncoupling, developing therapeutic strategies like folic acid to restore vascular function. Her work bridges molecular mechanisms with clinical applications in vascular pathologies. Analysis of her 2022-2025 publications reveals dominant themes: novel therapies for aortic aneurysms using folic acid/nifedipine combinations; pulmonary hypertension reversal via endothelial DHFR targeting; e-cigarette-induced endothelial damage in youth; and SARS-CoV-2 vascular complications. Her approach integrates genetic mouse models (NOX1 KO, apoE/NOX1 DKO), clinical cohorts, and redox biomarker development (e.g., circulating BH4 for aneurysm diagnosis). Dr. Cai directs the Cai Laboratory at UCLA, which employs multidisciplinary methods to study vascular repair mechanisms. Current projects include netrin-1 derivatives for vascular regeneration, epigenetic changes post-cardiac surgery, and environmental impacts of e-cigarettes/air pollution on endothelial health. Her team combines molecular biology, physiology, and translational research to identify therapeutic targets for cardiovascular diseases.

Varghese Johnمشاهده پروفایل

استاد

• Alzheimer's Disease
• Central Nervous System Disorders
• Neuropharmacology
• +۴ مورد دیگر

Varghese John , a Professor in the Department of Neurology at the David Geffen School of Medicine, University of California Los Angeles (UCLA) , specializes in Alzheimer's disease and central nervous system (CNS) disorders . His research focuses on identifying small molecule therapeutics targeting amyloid precursor protein (APP) proteolysis, tau propagation, and neuroinflammation through innovative drug discovery approaches. Key research areas include: BACE1 inhibition for APP-selective modulation Sirtuin 1 enhancers targeting ApoE4 pathology Exosome dynamics in neurodegenerative diseases γ-oscillation restoration for cognitive improvement Recent publications highlight: 2025: Three APP-selective BACE1 inhibitors with improved specificity 2024: γ-oscillation enhancers demonstrating cognitive benefits 2023: PAK inhibitors for Down syndrome models and multi-system gene expression in Parkinson's disease Awards include the Amgen Early Innovator Award (2019) for CNS enzyme delivery research. Current NIH grants focus on: R01AG073377 (2022-2027): sAPPalpha analogs for tau pathology RF1AG068116 (2021-2024): Humanin mimetics for AD R01AG051386 (2015-2021): ApoE4-targeted SirT1 modulation

Kosuke Funatoمشاهده پروفایل

استادیار

• Cancer Biology
• Epigenetics
• Drug Discovery
• +۲ مورد دیگر

Kosuke Funato is an Assistant Professor in the Department of Biochemistry and Molecular Biology at the University of Georgia and a member of the Center for Molecular Medicine. His long-term research focuses on developing therapies and early detection methods for glioblastoma, utilizing human embryonic stem cell-based tumor models. He holds a Ph.D. in Biophysics and Biochemistry from the University of Tokyo and completed postdoctoral training in Cancer/Stem Cell Biology at Memorial Sloan Kettering Cancer Center. His research explores glioblastoma heterogeneity through cutting-edge technologies in oncology and stem cell biology, with emphasis on intertumor and intratumor variations. Key areas include epigenetic regulation, cancer stem cell dynamics, and human-specific gene functions in tumor evolution. His work has been published in high-impact journals including Science, Cell Stem Cell, and EMBO Reports. Dr. Funato teaches BCMB 3100 and leads the Funato Lab at the Center for Molecular Medicine, where his team investigates subtype-specific vulnerabilities in glioblastoma. He received the IEEE CASE Best Conference Paper Award in 2021 and maintains collaborations across neuro-oncology and translational research communities.

• Microbiome Research
• Surgical Infections
• Anastomotic Healing
• +۳ مورد دیگر

John Alverdy is the Sarah and Harold Lincoln Thompson Professor and Executive Vice Chair of the Department of Surgery at the University of Chicago's Pritzker School of Medicine. He also serves as Director of Minimally Invasive Surgery and is affiliated with the Pritzker School of Molecular Engineering. His research focuses on the microbiome's role in surgical outcomes, particularly surgical site infections, anastomotic healing, and antibiotic resistance. Alverdy explores how dietary interventions and novel biomaterials can optimize postoperative recovery. Key research areas include microbiome modulation to prevent infections, the impact of Western diets on colorectal surgery outcomes, and the development of antimicrobial polymers. He emphasizes evidence-based approaches to combat antibiotic resistance and has pioneered studies on fecal microbiota transplant applications in sepsis. His recent articles highlight interdisciplinary efforts, combining microbiology, immunology, and materials science to address surgical challenges. Alverdy advocates for rigorous microbial culture practices in SSI research and promotes translational innovations like phosphorylated copolymers and vascularized flaps for hernia repair. Alverdy's work bridges clinical surgery with molecular mechanisms, aiming to reduce complications through a deeper understanding of host-microbiome interactions and surgical technique optimization.

Selma Masriمشاهده پروفایل

دانشیار

• Circadian Rhythms
• Sirtuins
• Metabolism
• +۲ مورد دیگر

Selma Masri is Associate Professor of Biological Chemistry at UC Irvine School of Medicine, investigating circadian regulation of metabolism and chromatin dynamics. Research explores sirtuin-mediated epigenetic control of metabolic pathways and circadian disruption in cancer. Key findings reveal partitioning of circadian transcription by SIRT6 and metabolic control mechanisms. Current studies examine DNA damage responses, tumor immunosuppression rhythms, and therapeutic modulation of circadian-metabolic interactions in disease.

Christina Vasquezمشاهده پروفایل

استادیار

• Marine Physiology
• Climate Change Impacts
• Environmental Stressors
• +۳ مورد دیگر

Christina Vasquez is an Assistant Professor of Biology at Loyola Marymount University (LMU), affiliated with the Frank R. Seaver College of Science and Engineering. She specializes in marine physiology, focusing on how marine organisms respond to environmental stressors like climate change. Her research integrates physiological techniques with ecological observations to understand survival and sustainability in coastal ecosystems. Education : B.S. in Animal Science from UC Davis (2006) M.S. in Biology from California State University, Northridge (2009) Ph.D. in Animal Molecular and Cellular Biology from the University of Florida (2013) Research Interests : Vasquez investigates the physiological responses of marine organisms, particularly invasive mussels, to multiple stressors such as heat, salinity fluctuations, and food scarcity. Her work emphasizes the role of sirtuins in cellular stress recovery and metabolic regulation. She also explores the broader implications of climate change on coastal ecosystems through courses like the Marine Physiology Field Lab , which provides students hands-on research experience. Key Projects : Recent studies include examining the effects of environmental stressors on Mytilus galloprovincialis in Marina del Rey, supported by LMU’s Seaver College Summer Opportunities for Advanced Research (SOAR) program. Students under her mentorship presented findings at the 2023 Western Society of Naturalists Conference. Awards : Recipient of the NSF Postdoctoral Research Fellowship in Biology for Broadening Participation (2014) during her postdoc at Cal Poly San Luis Obispo. Advising & Outreach : Vasquez advises first-year students, mentors research projects, and collaborates with the Coastal Research Institute and Santa Monica Bay Foundation to address coastal environmental challenges. She emphasizes student engagement, encouraging office-hour visits and active participation in research.

Laia Bosch-Preseguéمشاهده پروفایل

استاد

• Epigenetics
• Chromatin Dynamics
• Retinal Degenerations
• +۳ مورد دیگر

Laia Bosch-Presegué is a Professor at the University of Vic – Central University of Catalonia's Faculty of Health Sciences and Welfare, leading the Epigenetics and Tissue Transformation research line in TR2Lab. She holds a PhD from the Universitat Politècnica de Catalunya, specializing in G-protein-coupled receptors and retinal degenerations under Prof. Pere Garriga. Her postdoctoral work in Dr. Alex Vaquero's Chromatin Biology group at IDIBELL focused on chromatin dynamics and histone modifications. Currently, her research explores epigenetic mechanisms in pathologies and interventions to prevent or treat diseases. Her educational contributions include organizing the Biomedicine Workshops, engaging over 1,000 high school students annually in biomedical sciences. She collaborates with institutions like Vall Hebrón Research Institute and Hospital Germans Trias i Pujol on projects such as studying DCIS lesion progression and women's sexual health. Her work bridges academia and clinical research, emphasizing translational outcomes. Her publications span epigenetic regulation, chromatin structure, and retinal diseases, with notable contributions on sirtuins' dual roles in cancer and heterochromatin dynamics. She leads interdisciplinary initiatives, including a funded study on DCIS lesions by La Marató de 3Cat, integrating clinical and basic research.

Simon Allisonمشاهده پروفایل

عضو هیئت علمی

• Cancer cell metabolism
• NAD+-dependent enzymes
• Molecular dependencies in cancer
• +۴ مورد دیگر

Dr. Simon Allison is a Reader in the Department of Physical and Life Sciences at the School of Applied Sciences, University of Huddersfield. He is a member of the Pharmacology and Therapeutics Centre and Associate Member of the Cellular and Molecular Models of Disease Centre. Education: B.A. in Biological Natural Sciences (First Class Honors) from University of Cambridge PhD in Cancer Biology from University of Glasgow His research focuses on cancer metabolism and NAD+-dependent enzymology , particularly the exploitation of cancer cell metabolic rewiring and molecular dependencies. He investigates sirtuins and epigenetic alterations in cancer cells, aiming to elucidate mechanisms of action of novel anti-cancer agents. Recent publications highlight his work on self-assembling cryptate compounds (2024), cannabinoid cytotoxicity (2023), and omega-3 derivatives in prostate cancer (2022). These studies demonstrate his interest in chemical biology approaches to cancer therapy. He currently serves as External PhD Examiner at University of Manchester and Secretary for the British Society for Cell Biology. His research is funded by Kidscan and the University of Huddersfield.