جستجوی استاد راهنمای دانشگاهی

• Ion Channels
• Cardiovascular Physiology
• Endo-Lysosomal Trafficking
• +۴ مورد دیگر

Christian Wahl-Schott is a Professor at the Ludwig Maximilian University of Munich , leading the Cardiovascular Physiology and Pathophysiology group at the Biomedical Center Munich. His research spans ion channel mechanisms in cardiac, neurological, and metabolic diseases. Focus on HCN channels in cardiac pacemaking and autonomic regulation Endo-lysosomal ion channels in cholesterol homeostasis and viral pathogenesis Neural rhythms and epilepsy mechanisms Developed endo-lysosomal patch clamp and high-speed optical mapping Recent work explores the role of TPC2 and TRPML channels in Ebola virus entry and cardiac arrhythmia . Funded by the DFG and CRC 870 , his lab combines electrophysiology , optogenetics , and human organoid models . Key publications include: 2024: HCN4 channel regulation in sinoatrial node 2023: E-selectin and neutrophil inflammasome activation 2021: Heart-forming organoids for developmental studies 2020: cAMP-dependent pacemaker entrainment 2015: TPC channels as Ebola drug targets The lab maintains collaborations with institutions like the German Research Foundation and DZHK , and has developed Nature Protocols -cited methodologies in FRET microscopy and endo-lysosomal patch clamping .

Edward Glasscockمشاهده پروفایل

استاد

• Epilepsy
• Sudden Unexpected Death in Epilepsy (SUDEP)
• Neurogenetics
• +۳ مورد دیگر

Edward Glasscock is a Professor and C. Vincent Prothro Distinguished Chair in the Department of Biological Sciences at Southern Methodist University (SMU), where he also serves as Director of Graduate Studies. His research focuses on the genetic and physiological mechanisms of epilepsy and sudden unexpected death in epilepsy (SUDEP). Dr. Glasscock earned his Ph.D. from the University of California at Berkeley and completed postdoctoral training at Baylor College of Medicine. Leading the Cardiorespiratory Neurogenetics Laboratory , his work investigates epilepsy and SUDEP through genetic mouse models. His team employs in vivo , ex vivo , and in vitro electrophysiological techniques alongside pharmacology, histology, and molecular analyses. Key research areas include: Neurogenetics of Kv1.1 channelopathies Sex-specific differences in SUDEP susceptibility Cardiorespiratory biomarkers of seizure-related mortality Brain-heart-lung interactions during epileptic events Analysis of Dr. Glasscock's recent publications reveals a concentrated focus on Kv1.1 channel dysfunction, SUDEP biomarker development, and translational mouse models bridging neuroscience and cardiology. His work demonstrates how ion channel mutations disrupt cardiorespiratory physiology during seizures, with significant implications for predicting and preventing epilepsy-related mortality. Dr. Glasscock mentors a multidisciplinary research team, with notable achievements including: PhD student Kelsey Paulhus-Halvorson's successful dissertation defense (April 2024) Postdoctoral fellow Dr. Man Si receiving the 2025 Cranefield Postdoctoral Fellow Award Multiple undergraduate award winners at SMU Research & Innovation Week In 2023, his lab secured a 5-year NIH R01 grant to identify brain-heart-lung dysfunction patterns as SUDEP biomarkers. The Cardiorespiratory Neurogenetics Laboratory operates within SMU's research infrastructure, featuring specialized facilities for electrophysiology and behavioral analysis while maintaining active collaborations with clinical researchers at Barrow Neurological Institute.

Alicia D'Souzaمشاهده پروفایل

پژوهشگر ارشد

• Cardiac Physiology
• Cardiac Ion Channels
• Arrhythmia Mechanisms
• +۴ مورد دیگر

Dr Alicia D'Souza is an Honorary Senior Research Fellow at the University of Manchester's Division of Cardiovascular Sciences. She holds a PhD in cardiac physiology from the University of Central Lancashire (2011). Her research focuses on cardiac ion channel regulation, arrhythmia mechanisms, microRNA control, and circadian rhythm impacts on heart function. Funded by the British Heart Foundation, her work explores pro-arrhythmic mechanisms in athletes and ageing populations. Education: PhD (2011, University of Central Lancashire) Research Themes: Cardiac ion channels, microRNA regulation, athletic-induced arrhythmias, circadian clocks in pacemaking Her team employs integrative approaches combining animal models, genomic technologies, and physiological studies to understand ion channel plasticity. Key projects include investigating microRNA inhibitors for sinus node dysfunction and circadian clock influences on cardiac conduction. She has secured grants from the BHF and collaborates internationally. Awards: 2019: International Society for Heart Research Richard J Bing finalist 2019: University of Manchester ‘Researcher in the Spotlight’ 2018: Inaugural Editorial Board Fellowship of Journal of Physiology Her work has been featured in media (e.g., BBC) and she actively engages in invited talks and editorial roles. Current projects include preclinical microRNA inhibitor development and studying arrhythmias in athletes.

• Cardiac Conduction System
• Molecular Biology
• Electrophysiology
• +۵ مورد دیگر

Halina Dobrzynski is a Senior Lecturer in Cardiovascular Sciences at the University of Manchester, School of Medicine. She holds a visiting professor position at Jagiellonian University's Department of Anatomy (Cracow, Poland) and earned a D.Sc. from Jagiellonian University in 2023. Her research focuses on the macro/micro-anatomy and molecular biology of the cardiac conduction system, particularly the sinoatrial and atrioventricular nodes, using advanced imaging (microCT, AI, VR) and molecular techniques. She has supervised over 20 PhD students and postdocs, with active grants exceeding £7 million from BHF, NIH, and others. Key awards include the 2014 Best Pre-Clinical Teacher award at Manchester. Education: B.Sc. (1996) and Ph.D. (2000) in Biological/Biomedical Sciences from the University of Leeds. Postdoctoral roles at Leeds, NIH, Washington University, and others. Research interests emphasize structural-functional relationships in the cardiac conduction system across species (human, rodent, large animals) and conditions (aging, disease, exercise). Key projects include circadian rhythms in pacemaking, microRNA regulation of ion channels, and bio-pacemaker development. Over 138 publications span cardiac electrophysiology, imaging innovations, and translational cardiology. Active in grant review (BHF, NIH) and editorial roles (Frontiers in Physiology). Public engagement includes science outreach programs for youth and lectures on cardiac physiology. Teaching/admin roles include Radiation Protection Supervisor, Manchester Gold Mentor, and leadership in medical student education. Grants managed include £2.5M BHF PhD studentships and a £4.6M Leducq Network grant (2019-2024).

• Cardiac Electrophysiology
• Computational Biology
• Biomedical Engineering
• +۳ مورد دیگر

Professor Henggui Zhang is a faculty member in the Biological Physics Group at the University of Manchester. His research focuses on computational modeling of cardiac electrophysiology, with emphasis on arrhythmia mechanisms, ion channel dysfunction, and spatiotemporal complexity of biological systems. He holds a Fellowship of the Royal Society of Biology and contributes to sustainable development goals in advanced medical materials and digital health. Research Interests Cardiac arrhythmia modeling at single-cell and tissue levels Chaotic time series analysis and control of cardiac dynamics Computational studies of genetic disorders like Short QT Syndrome Electrophysiological effects of drugs and pollutants Key Contributions His recent work explores circadian rhythm impacts on arrhythmia susceptibility, novel treatments for atrial fibrillation, and AI-driven ECG classification systems. Over 44 supervised students and 172 research outputs underscore his prolific academic leadership. Awards Fellow of Royal Society of Biology (2019) Society Fellowship (Biology) (2019) Grants & Projects Co-Investigator in the 'Manchester Bioelectronics Network' (2018), advancing interdisciplinary bioelectronics research. Labs & Teams Leads the Biological Physics Group, collaborating on projects like AI-based medical diagnostics and cardiac modeling.

• Cardiac Electrophysiology
• Atrial Fibrillation Ablation
• Sinus Node Physiology
• +۳ مورد دیگر

Rani Jana L Kronenberger is an active researcher at Vrije Universiteit Brussel's Faculty of Medicine and Pharmacy, specializing in Clinical Sciences with focus on cardiac electrophysiology. Her work primarily centers on heart rhythm disorders within the Heart Rhythm Research Brussels unit. As an unpaid academic researcher, she maintains significant scholarly output and institutional engagement. Her research interests span Cardiac Electrophysiology , Atrial Fibrillation Ablation , Sinus Node Physiology , Radiofrequency Ablation , 3D Printing Applications in Cardiac Surgery , and Synthetic Data Generation for biomedical research. Recent publications demonstrate expertise in hybrid ablation techniques, sinus node mapping, and innovative approaches to arrhythmia management. Analysis of her 20 most recent research outputs (2020-2025) reveals strong emphasis on cardiac rhythm disorders with particular focus on atrial fibrillation and sinus tachycardia treatments. Her work integrates engineering approaches like 3D printing and CTGAN synthetic data generation with clinical electrophysiology, reflecting interdisciplinary collaboration across cardiology, surgery, and biomedical engineering. Best BAST Trainer-Trainee Paper Presentation (2022) Kronenberger actively participates in academic knowledge dissemination through 16 recorded activities including conference presentations (5), external academic talks (3), conference talks (3), workshop participation (2), and school outreach events (2). She has contributed to 3 press/media features including scientific videos and medical education content about cardiac rhythm disorders. Her h-index of 44 demonstrates significant scholarly impact in cardiac electrophysiology research.

• Cardiac Electrophysiology
• Arrhythmia Mechanisms
• Sex Differences in Cardiac Function
• +۳ مورد دیگر

Prof. Céline Fiset is a Full Professor at the Faculty of Pharmacy, Université de Montréal, and a researcher at the Institut de cardiologie de Montréal. Her work focuses on cardiac electrophysiology, particularly sex differences in cardiovascular function, hormonal regulation of ion channels, and arrhythmia mechanisms. She leads projects funded by major Canadian health agencies like the Canadian Institutes of Health Research (CIHR) and the Heart and Stroke Foundation. Prof. Fiset has supervised numerous PhD and Master’s students since 1995, exploring topics such as pregnancy-induced arrhythmias, sex-based differences in atrial fibrillation, and hormonal effects on cardiac repolarization. Research Highlights: Expertise in sinoatrial node function, cardiac ion channels, and antiarrhythmic pharmacology. Investigates how sex hormones (estrogens, testosterone) modulate cardiac electrical activity. Studies arrhythmia mechanisms in transgenic mouse models (e.g., angiotensin II receptor overexpression). Examines pregnancy-related cardiac adaptations, such as increased heart rate and atrial remodeling. Grants & Funding: Leading a CIHR-funded project (2021–2028) on estrogen’s role in pregnancy-related arrhythmias. Recipient of multiple CRSNG (Natural Sciences and Engineering Research Council) grants for sinoatrial node ion channel studies. Collaborates on projects exploring sex-dependent cardiac protection via mTOR pathways. Advising & Training: Supervised over 30 graduate students since 1995, with recent focus on atrial fibrillation mechanisms and pregnancy-related electrophysiology. Guides research on translational models (e.g., iPSC-derived cardiomyocytes) to study sex differences in cardiac disease. Affiliations: Member of the Institut de cardiologie de Montréal Research Centre (ICM). Associated with the GRUM (University Research Group on Medicines).

• Cellular Physiology
• Cardiac Electrophysiology
• Ion Channel Biology
• +۳ مورد دیگر

Leonid Tyan is an Associate Research Scientist in the Department of Cellular & Molecular Physiology at Yale School of Medicine. He holds a PhD from Eberhard Karls Universität Tübingen (2012). His research focuses on ion channel biology, cellular physiology, and mechanisms underlying cardiac arrhythmias, particularly atrial fibrillation. He investigates the role of caveolae, membrane potential regulation, and calcium signaling in cardiac and cellular contexts. Collaborations include work with David Zenisek, Michael Caplan, and Mustafa Khokha. His studies span from molecular mechanisms to computational modeling of cardiac cells, contributing to understanding arrhythmogenesis and developmental processes. Research Interests: Cardiac electrophysiology, ion channel modulation, caveolar microdomains, membrane potential dynamics, and calcium signaling in disease contexts. Key Projects: Mechanisms of atrial fibrillation, caveolin-3's role in ion channel regulation, and mathematical modeling of atrial myocytes. Publications highlight contributions to understanding caveolar-mediated arrhythmias, calcium-dependent processes in pluripotency, and genetic influences on cardiac rhythm. His work bridges experimental and computational approaches to elucidate disease mechanisms.

• Cardiovascular Disease
• Heart Failure
• Cardiac Physiology
• +۳ مورد دیگر

Dr. Min Zi is a Researcher in the Division of Cardiovascular Sciences at the University of Manchester. His research focuses on cardiac remodelling mechanisms, heart failure, and arrhythmias using mouse models. With 57 publications and a PhD (2017), he explores molecular and physiological pathways in cardiovascular diseases. Collaborations span international teams. Education: Doctor of Philosophy in Medicine (General) – Completed 2017 Research Interests: Dr. Zi investigates heart failure pathogenesis, cardiac hypertrophy, and arrhythmia mechanisms. His work integrates molecular biology, genetics, and physiology to uncover novel therapeutic targets for cardiovascular diseases. Key areas include fetal gene expression in heart protection and immune system interactions in cardiac dysfunction. Advising & Grants: Supervised 1 doctoral student (details not specified) No grants explicitly listed in provided text Labs/Teams: Active within the Division of Cardiovascular Sciences, collaborating on projects involving transcriptomics and drug development for heart failure.

T. Alexander Quinnمشاهده پروفایل

استاد

• Cardiovascular Physiology
• Cardiac Electrophysiology
• Mechano-Electric Coupling
• +۳ مورد دیگر

Dr. T. Alexander Quinn is a Professor in the Department of Physiology and Biophysics at Dalhousie University's School of Biomedical Engineering. His research explores cardiac autoregulation, mechano-electric coupling, and arrhythmia mechanisms using multiscale experimental and computational models across species. Based in Halifax, Nova Scotia, he actively recruits graduate students for Fall 2025 research projects. BSc (McGill University) MSc & PhD (Columbia University) Postdoctoral training: University of Oxford, Imperial College London Research Focus : Cardiac autoregulation mechanisms from organ to subcellular levels Mechano-electric interactions in heart rhythm dynamics Computational modeling of cardiac function across species Zebrafish and mammalian models for cardiac research Development of targeted anti-arrhythmic therapies Publication Trends : Recent work spans zebrafish cardiac modeling (2025, 2024), ischemia-induced arrhythmogenesis (2025), sinoatrial node dynamics (2022), and historical perspectives on cardiac biophysics (2022). Key methodologies include optogenetics, computational simulations, and multispecies electrophysiology. Scientific Recognition : King Charles III Coronation Medal Sir Harcourt Caughey Award (Auckland Medical Research Foundation) J.A.F. Stevenson Award (Canadian Physiological Society) Dalhousie Medical Research Foundation Award Heart & Stroke Foundation of Nova Scotia Award Teaching Roles : PHYL 4680/5568: Advanced Cardiovascular Physiology PHYL 2044: Human Systems Physiology BMNG 5062: Biomedical Engineering Foundations MNSC 6101: Cellular Neuroscience MED 2: Metabolism II

• Cardiac Electrophysiology
• Computational Biology
• Arrhythmia Mechanisms
• +۲ مورد دیگر

Zhilin Qu is a Professor-in-Residence in the Department of Computational Medicine at the David Geffen School of Medicine, University of California, Los Angeles. His research focuses on cardiac electrophysiology, arrhythmia mechanisms, and computational modeling of heart dynamics, supported by multiple NIH grants as Principal Investigator. Dr. Qu's work spans cardiac calcium dynamics, spiral wave behavior, arrhythmogenic substrates, and multi-scale modeling. He investigates phenomena like alternans, early afterdepolarizations, and reentry using mathematical frameworks to bridge cellular processes and whole-organ dysfunction. Recent studies emphasize mitochondrial roles in arrhythmias, fibroblast-myocyte interactions, and disease-specific mechanisms (e.g., Brugada syndrome, long QT). His publications demonstrate a consistent focus on nonlinear dynamics in cardiac systems, with articles frequently combining computational simulations, animal models, and theoretical physics. Trends include spatially discordant alternans, ion channel kinetics, and the impact of tissue heterogeneity on wave stability. Dr. Qu leads NIH-funded projects including 'A population-based in silico platform for arrhythmia prediction' (R01HL134709) and 'Mitochondria and arrhythmogenic calcium cycling dynamics' (R01HL133294). He collaborates extensively with experimental labs to validate models and translate findings to clinical contexts.

Damiano Angoliمشاهده پروفایل

دانشگاهی

• Biophysics of ion channels
• Electrophysiology
• Drug discovery
• +۳ مورد دیگر

Dr. Damiano Angoli is a Research Assistant Professor in the Department of Biomedical Engineering at Florida International University. His research focuses on the biophysics of ion channels and transporters, with a particular emphasis on electrophysiological techniques applied to neurovascular, cardiovascular, and respiratory systems physiology. He leads the Vascular Physiology and Biotransport laboratory and has collaborated extensively with the private sector on drug discovery initiatives, including validating amino acid formulations for epithelial dysfunction treatments. Education : B.S. and Master in Biology from the University of Milan, Italy Ph.D. in Translational and Experimental Medicine from the University of Insubria, Italy (2018) Research Interests : Angoli’s work bridges basic science and translational medicine. Key areas include ion channel dysfunction in disease states, electrophysiological monitoring systems for rodent models, and the development of novel therapeutic strategies targeting epithelial and smooth muscle physiology. His lab employs advanced electrophysiological techniques and integrates experimental models with industrial partnerships. Publications : Over 13 peer-reviewed articles since 1996, spanning ion channel biology, cardiac electrophysiology, and drug discovery. Recent work emphasizes cytokine-altered epithelial ion transport and urodynamic monitoring systems. Labs & Teams : Directs the Vascular Physiology and Biotransport lab, focusing on neurovascular coupling applications and translational biophysics.

Arnt Eltvedt Fianeمشاهده پروفایل

استاد

• Cardiovascular Surgery
• Heart Transplantation
• Mechanical Circulatory Support
• +۴ مورد دیگر

Arnt Eltvedt Fiane is a Professor in the Department of Cardiothoracic Surgery at the University of Oslo. His primary affiliation is with Oslo University Hospital's Rikshospitalet location. He focuses on advanced cardiac surgical interventions including heart and lung transplantation, mechanical circulatory support devices (LVADs), and post-transplantation autonomic reinnervation mechanisms. Research interests emphasize cardiovascular device innovation, immunosuppression protocols in transplantation, and clinical outcomes of critical care interventions like ECMO. His work spans translational studies on cardiac fibrosis inhibition, accelerometer-based LVAD monitoring, and obesity's impact on device efficacy. Key contributions include national lung transplantation trend analyses and international registry studies (EUROMACS) on LVAD patient outcomes. He has authored over 100 peer-reviewed articles in journals like The Lancet Respiratory Medicine and Circulation Research.

Michela Ottoliaمشاهده پروفایل

استاد

• Cardiac Physiology
• Cellular Calcium Signaling
• Membrane Transport Proteins
• +۳ مورد دیگر

Mic is a Professor-in-Residence in the Department of Anesthesiology at the David Geffen School of Medicine, UCLA. Her research focuses on the structural and functional mechanisms of the cardiac sodium-calcium exchanger (NCX1), particularly its role in cardiac physiology, arrhythmogenesis, and disease. Ottolia leads NIH-funded studies investigating sodium-dependent inactivation of NCX1 and its implications for heart function. Research Interests: Ottolia’s work centers on ion transport proteins, cellular calcium regulation, and membrane physiology. Key topics include NCX1 structure-function relationships, pharmacological modulation of ion channels, and arrhythmia mechanisms. Her lab integrates structural biology, electrophysiology, and genetic approaches to study cardiac ion homeostasis. Grants & Awards: Ottolia has served as Principal Investigator (PI) or Co-PI on multiple NIH R01 grants, including projects exploring sodium-dependent NCX1 inactivation (R01HL152296), cellular calcium regulation (R01HL147569), and NCX1 operational mechanisms (R01HL130308). Recent Publications: Recent work highlights structural insights into NCX1 activation/inhibition, AV node electrophysiology, and BK channel roles in inflammation. Ottolia’s publications span journals like Cell Calcium , Nature Communications , and Proceedings of the National Academy of Sciences .

Eilidh MacDonaldمشاهده پروفایل

پژوهشگر ارشد

• Cardiac Electrophysiology
• Sinoatrial Node Mechanics
• Heart Failure
• +۲ مورد دیگر

Eilidh MacDonald is a Postdoctoral Research Fellow in Cardiovascular and Metabolic Health at the University of Glasgow. Her work explores cardiac pacemaker mechanisms, arrhythmia, and heart failure, using models from zebrafish to mammals. She received the 2022 British Society for Cardiovascular Research Early Career Award and a Journal of Physiology Editorial Fellowship. Her publications in Frontiers in Physiology and Cardiovascular Research examine sinoatrial node mechanosensitivity, neurohumoral regulation, and cardiac remodelling. She collaborates globally and supervises PhD students.