Zhilin Qu

Zhilin Qu is a Professor-in-Residence in the Department of Computational Medicine at the David Geffen School of Medicine, University of California, Los Angeles. His research focuses on cardiac electrophysiology, arrhythmia mechanisms, and computational modeling of heart dynamics, supported by multiple NIH grants as Principal Investigator.

Dr. Qu's work spans cardiac calcium dynamics, spiral wave behavior, arrhythmogenic substrates, and multi-scale modeling. He investigates phenomena like alternans, early afterdepolarizations, and reentry using mathematical frameworks to bridge cellular processes and whole-organ dysfunction. Recent studies emphasize mitochondrial roles in arrhythmias, fibroblast-myocyte interactions, and disease-specific mechanisms (e.g., Brugada syndrome, long QT).

His publications demonstrate a consistent focus on nonlinear dynamics in cardiac systems, with articles frequently combining computational simulations, animal models, and theoretical physics. Trends include spatially discordant alternans, ion channel kinetics, and the impact of tissue heterogeneity on wave stability.

Dr. Qu leads NIH-funded projects including 'A population-based in silico platform for arrhythmia prediction' (R01HL134709) and 'Mitochondria and arrhythmogenic calcium cycling dynamics' (R01HL133294). He collaborates extensively with experimental labs to validate models and translate findings to clinical contexts.