جست‌وجوی استاد و پژوهشگر

Boris Hejblumمشاهده پروفایل

پژوهشگر

• Longitudinal Analysis
• High-dimensional Biomedical Data
• Bayesian Nonparametrics
• +۷ مورد دیگر

Boris Hejblum is a Researcher at the Inserm Bordeaux Population Health Research Center (U1219), co-directing the SISTM team affiliated with INRIA and INSERM. He holds a Research Faculty position, focusing on longitudinal analysis of high-dimensional biomedical data. Previously, he was a tenured Associate Professor (2015–2021) at the Bordeaux School of Public Health, University of Bordeaux, and completed his Ph.D. in Biostatistics at ISPED (Bordeaux) in 2015 under Professors François Caron and Rodolphe Thiébaut. He earned his Master's from ENSAI (France’s National School of Statistics) in 2011. His research spans Bayesian nonparametric methods, optimal transport, single-cell data analysis, and vaccine surrogate markers. Notable contributions include tcgsaseq (RNA-seq differential analysis), CytOpT (flow cytometry analysis), and epidemiological modeling tools like EpidemiOptim. He collaborates widely, with projects in genomics, immunology, and public health. Education: Accreditation to Supervize Research (HDR), 2024, Université de Bordeaux PhD in Biostatistics, 2015, Université de Bordeaux Engineer in Statistics, 2011, ENSAI (Rennes) MSc Statistics, 2011, Université de Rennes Research Interests: Longitudinal data analysis High-dimensional biomedical data integration Optimal transport applications in cytometry Vaccine efficacy and surrogate markers Electronic health record analytics Grants & Teams: Leads the SISTM team (INRIA/INSERM), involved in projects like AI4scMed and SMATCH. Collaborates with institutions globally on HIV vaccine trials and pandemic modeling. Labs/Teams: Co-directs SISTM team at INRIA/INSERM, affiliated with Bordeaux Population Health Center.

Eliezer Van Allenمشاهده پروفایل

دانشیار

• Computational Oncology
• Cancer Genomics
• Immunotherapy
• +۵ مورد دیگر

Eliezer Van Allen, MD, is an Associate Professor of Medicine at Harvard Medical School and Chief of the Division of Population Sciences at Dana-Farber Cancer Institute. He holds the Chandra Nohria Family Chair for AI in Cancer Research. His research focuses on clinical computational oncology, integrating genomics, artificial intelligence, and clinical data to advance precision cancer medicine. Key areas include tumor immune interactions, genomic drivers of resistance to therapies, and inherited genetic risk factors in pediatric and adult cancers. Education: Medical degree from the University of California, Los Angeles (UCLA), followed by residency in Internal Medicine at the University of California, San Francisco (UCSF), and a fellowship in Medical Oncology at Dana-Farber/Partners CancerCare. Research Interests: Computational oncology, cancer genomics, immunotherapy response mechanisms, and AI-driven biomarker discovery. His lab develops tools like the Molecular Oncology Almanac and collaborates on patient-partnered initiatives such as the Metastatic Prostate Cancer Project. Recent work emphasizes germline variants in pediatric cancers, myeloid-mediated resistance in prostate cancer, and biologically interpretable AI models for tumor analysis. Awards: Recognized as one of the world's most highly cited researchers in cancer genomics (2024). Holds the Chandra Nohria Chair for AI in Cancer Research. Advising & Grants: Mentored over 20 students, including Kevin, Nicita Mehta, and Samantha Hoffman. His lab’s work is supported by grants focused on computational oncology, precision medicine, and AI ethics in healthcare. Labs/Teams: Director of the Clinical Computational Oncology Lab at Dana-Farber, which combines computational biology, clinical data science, and translational research. Collaborates with institutions like the Broad Institute and patient advocacy groups.

Lior Pachterمشاهده پروفایل

استاد

• Computational Biology
• Genomics
• Functional Genomics
• +۵ مورد دیگر

Lior Pachter is the Bren Professor of Computational Biology and Computing and Mathematical Sciences at the California Institute of Technology (Caltech), a position he has held since 2017. Previously, he served at the University of California, Berkeley from 1999 to 2018, progressing through roles including Assistant, Associate, and Full Professor in the departments of Mathematics, Molecular and Cellular Biology, and Computer Science. He holds a B.S. in Mathematics from Caltech (1994) and a Ph.D. in Applied Mathematics from MIT (1999). His research focuses on computational methods for genomics, including functional genomics, single-cell sequencing, and algorithm development for analyzing high-throughput data. Key areas include RNA biology, chromatin interactions, and the integration of multi-omics datasets. Pachter’s lab develops tools like kallisto and bustools for RNA-seq quantification, emphasizing open-source software and reproducibility. Notable awards include the NSF CAREER Award, Sloan Research Fellowship, and Miller Professorship. He has authored over 100 papers, with recent work addressing viral detection at single-cell resolution, biophysical modeling of gene expression, and transcriptome quantification. Teaching spans courses in computational biology, mathematics, and machine learning at both Caltech and UC Berkeley. His lab’s interdisciplinary collaborations span biochemistry, statistics, and computer science, aiming to bridge experimental and computational approaches in genomics. Current projects include the Commons Cell Atlas and viral sequence discovery using novel sequencing techniques.

Audrey Sederbergمشاهده پروفایل

استادیار

• Theoretical Neuroscience
• Artificial Neural Networks
• Biological Neural Networks
• +۴ مورد دیگر

Audrey Sederberg is an Assistant Professor in the School of Psychology at the Georgia Institute of Technology. Her research focuses on theoretical neuroscience, integrating computational models with experimental data to understand neural dynamics in biological and artificial systems. She leads the MaTRIX Laboratory, which examines how neural circuits process information across scales, from single neurons to population-level activity patterns. Education: Ph.D. in Physics, Princeton University (Advisors: William Bialek and Matthias Kaschube) B.S. in Physics, Harvey Mudd College (Advisor: Vatche Sahakian) Research Interests: Theoretical frameworks for analyzing high-dimensional neural datasets Latent dynamics bridging spiking activity and local field potentials Neural criticality and emergent system properties Development of sensory cortical circuits Publications highlight contributions to: Real-time cortical state estimation using machine learning Role of latent variables in spatiotemporal criticality Decoding sensory stimuli in awake mouse cortex Lab Activities: The MaTRIX Lab emphasizes theory-driven approaches with deep experimental collaboration, addressing questions about neural network robustness, parameter relationships in circuit behavior, and integrating single-cell RNAseq data into circuit models.

• Cardiovascular Disease
• Metabolic Syndrome
• Vascular Physiology
• +۳ مورد دیگر

Dr. Maria Jelinic is a Senior Lecturer in the Department of Microbiology, Anatomy, Physiology & Pharmacology at La Trobe University. Her research focuses on cardiovascular and metabolic diseases, particularly hypertension, obesity, and diabetes. She investigates inflammatory mechanisms and novel therapeutic strategies using rodent models. Dr. Jelinic holds a PhD from the University of Melbourne (2017) and has secured $3.7M in competitive funding. She is actively involved in training the next generation of biomedical researchers. Research Interests: Mechanisms driving cardiac, vascular, and renal complications in cardiometabolic diseases Sex differences in metabolic syndrome progression Development of mouse models for human atherosclerosis Pharmacological interventions targeting immune cells to reduce end-organ damage Articles: Her recent work emphasizes hypertension mechanisms, metabolic syndrome, and single-cell transcriptomics. Studies include sex-specific effects of diets, IL-18's role in vascular pathology, and hesperidin's insulin-resistance impact. Grants & Funding: Over $3.7M secured, including an NHMRC/National Heart Foundation Early Career Fellowship (2018-2022). She collaborates widely and mentors HDR students. Labs/Teams: Active in the Centre for Cardiovascular Biology and Disease Research at La Trobe University.

• Cardiovascular Disease
• Systems Biology
• Single-cell Omics
• +۶ مورد دیگر

Associate Professor Alexander Pinto is a co-appointed faculty member between La Trobe University and the Baker Heart and Diabetes Institute, leading the Cardiac Cellular Systems laboratory. His research focuses on understanding how cellular networks in the heart contribute to heart failure, particularly under conditions like hypertension, obesity, and diabetes. He employs cutting-edge methods including single-cell omics, 3D imaging, and mouse genetics to explore reversible cardiac alterations. Research Interests: Cardiovascular disease mechanisms Systems biology and computational biology Single-cell genomics and transcriptomics 3D microscopy and imaging techniques Cellular interactions in fibrosis Sex-specific pathophysiology Recent Research Trends: His work emphasizes multi-omic analyses of cardiac non-myocytes, sex-specific responses to hypertension, and adipose tissue contributions to cardiovascular disease. Notable contributions include identifying novel drivers of vascular fibrosis and embryonic-derived progenitor cells in aorta development. Grants: Heart Foundation of Australia Future Leader Fellowship (2024–2027) NHMRC Ideas Grant (2020–2023) Collaborations involve labs in Australia and the U.S., with a focus on translational cardiovascular research.

Kjell Petersenمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Genomics
• Cancer Biology
• +۷ مورد دیگر

Kjell Petersen holds the position of Researcher at the Department of Informatics and the Computational Biology Unit at the University of Bergen. His research focuses on computational biology, bioinformatics, and genomics with applications in cancer biology, epigenetics, and environmental toxicology. He has contributed to the development of national e-infrastructure initiatives like NeLS (Norwegian e-Infrastructure for Life Sciences) and ELIXIR.NO, promoting data management and interoperability in life sciences research. PhD in Structural Biology (2002), University of Bergen Postdoctoral research in bioinformatics and computational methods Key research areas include transcriptomics, gene expression analysis, and viral metagenomics. He has published extensively on topics such as immune response characterization in fish, genomic profiling of cancer metastasis, and the integration of omics data across disciplines. Petersen's work bridges computational methods with experimental biology, addressing challenges in data-driven biomedical research. His articles highlight contributions to understanding cellular responses to environmental toxins, developing bioinformatics tools for variant visualization, and exploring phenotypic differences in brain cancer models. Petersen collaborates widely with institutions across Norway and internationally, contributing to projects like FUGE Bioinformatics and Digital Life Norway, which aim to advance national research infrastructure.

• Immunology
• Veterinary Medicine
• Comparative Biomedical Sciences
• +۶ مورد دیگر

Shane Burgess is a Professor at the University of Arizona's School of Animal and Comparative Biomedical Sciences, part of the College of Agriculture, Life & Environmental Sciences. His research focuses on immunology, comparative biomedical sciences, and proteomics, with applications in avian biology and equine health. He explores how exercise influences immune responses, particularly in contexts like SARS-CoV-2 immunity, and investigates molecular mechanisms underlying equine asthma and avian physiology. Key research areas include T-cell dynamics, vaccine efficacy, and systems biology approaches to annotate genomes. He leads projects such as the Avian RNAseq Consortium and contributes to the Functional Annotation of Animal Genomes (FAANG) initiative. His work bridges basic science and applied health, addressing challenges in animal and human health. Recent studies highlight his focus on immune responses to exercise, viral infections, and chronic respiratory conditions. Collaborative efforts in proteomics and genomics aim to advance understanding of disease mechanisms and improve diagnostic tools. No scientific awards or grants are explicitly listed, but his extensive publication record reflects sustained contributions to the field.

• Immunology
• Cell Biology
• Cytotoxic T Lymphocytes (CTLs)
• +۷ مورد دیگر

Gillian Griffiths is a Professor and Chair of the Department of Cell Biology at Yale School of Medicine. Her research focuses on the fundamental cell biological mechanisms of cytotoxic T lymphocytes (CTLs), including polarized secretion of cytolytic proteins, immune synapse dynamics, and ectocytosis-driven T cell receptor regulation. She investigates organelle coordination (centrosome, lysosomes, mitochondria) during immune responses and its implications for cancer immunotherapy, with recent work on CAR T cell optimization and transcriptional adaptation in T cells. PhD: University of Cambridge, MRC Laboratory of Molecular Biology (1984) Postdoc: Stanford University Former Director: Cambridge Institute for Medical Research (2002-2017) Her work combines genetics, transcriptomics, biochemistry, and high-resolution microscopy to reveal parallels between immune synapses and cilia, roles for Hedgehog signaling, and novel mitochondrial translation requirements for sustained CTL killing. Key projects explore ectocytosis as a universal receptor signaling termination mechanism and energy metabolism defects in immunodeficiency syndromes. Awarded the Royal Society Buchanan Medal (2019), she is a Fellow of the Royal Society (2013), EMBO (2006), and Academy of Medical Sciences (2005). Her lab operates at the Boyer Center for Molecular Medicine (295 Congress Avenue, New Haven, CT 06510) with administrative support from Emily Dering.

Margo Emontمشاهده پروفایل

استادیار

• Adipocyte Biology
• Metabolic Diseases
• Adipose Tissue Heterogeneity
• +۳ مورد دیگر

Margo Emont is an Assistant Professor at the University of Chicago in the Department of Medicine-Endocrinology. She leads the Emont Lab, which investigates adipocyte (fat cell) biology with a focus on how adipose tissue regulates whole-body metabolism and contributes to diseases like obesity and type 2 diabetes. Her research utilizes single-cell genomics, transcriptomics, and proteomics to characterize adipocyte subpopulations in humans and mice. Research Focus Dr. Emont's work centers on: Adipose tissue heterogeneity and the functional differences between adipocyte subtypes Molecular mechanisms linking adipose tissue dysfunction to metabolic diseases Therapeutic interventions (e.g., semaglutide, bariatric surgery) and their effects on adipose composition Development of novel methodologies for adipose tissue analysis (e.g., single-nucleus RNA sequencing) Publication Trends Her recent publications (2019-2025) predominantly explore adipose tissue biology through advanced genomic and transcriptomic approaches. Key themes include: Single-cell mapping of white/brown adipose subpopulations Metabolic regulation via adipocyte signaling pathways (e.g., GIP receptor, IL-13) Cross-species comparisons of adipose function Translational research on obesity therapeutics Funding and Labs Dr. Emont leads multiple NIH-funded projects: K01DK134806 (NIDDK): Investigating human adipocyte subpopulations (2022-2027) F32DK124914: Regulation of IRF4 in adipocytes (2020-2022) F31DK112625: Thermogenesis via TRPA1 (2016-2019) The Emont Lab employs techniques including flow cytometry, single-cell genomics, and metabolic phenotyping to study adipose tissue in health and disease.

Matthew Lorinczمشاهده پروفایل

استاد

• Developmental Genetics
• Genomics
• Chromatin
• +۷ مورد دیگر

Matthew Lorincz is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC), Faculty of Medicine. His research focuses on epigenetic mechanisms, including DNA methylation, histone modifications, and chromatin remodeling, particularly in the context of mammalian development and disease. He is affiliated with the Life Sciences Institute and employs cutting-edge technologies like CRISPR/Cas9, low-input ChIP-seq, and allele-specific methylomic analysis. Education: PhD in Medical Genetics Research interests center on: Interplay between DNA methylation and histone modifications Epigenetic regulation in early embryonic and germline development Mechanisms of chromatinopathies and neurodevelopmental disorders Role of retrotransposons in genomic imprinting Recent research trends from his publications (2017–2025) highlight: Epigenetic cross-talk during pluripotency Lineage-specific imprinting mechanisms Transgenerational effects of chromatin regulators Transposable element repression in early embryos Allele-specific epigenomic analysis Technological advancements in low-input profiling Key projects include: Molecular basis of Weaver Syndrome (NSD1/H3K36me2) Heritability of histone modifications across fertilization Role of H3K9 methyltransferases in transcriptional regulation Imprinting establishment via LTR retrotransposons in oocytes Lorincz's lab utilizes: Mouse models for developmental studies CRISPR/Cas9 for chromatin factor knockout ULI-ChIP-seq, PBAT, RNAseq for genome-wide analysis Custom pipelines (e.g., MEA, ALEA) for data integration

Hope Healeyمشاهده پروفایل

مدرس

• Bioinformatics
• Genomics
• Evolutionary Biology
• +۳ مورد دیگر

Hope Healey is a Bioinformatics Lecturer at the University of Oregon's Knight Campus for Accelerating Scientific Impact, specifically within the Bioinformatics and Genomics Program under the Knight Campus Graduate Internship Program. She joined the Knight Campus in January 2025. Her research focuses on evolutionary and developmental genetics of syngnathid fishes, leveraging advanced genomic techniques like single-cell sequencing and chromosome-scale genome assemblies. Healey earned her PhD in Biology from the University of Oregon (2024), studying syngnathid fish head evolution in Bill Cresko's lab. She holds a B.S. in Zoology from Michigan State University (2018), where she researched electric fish genetics and zooplankton ecology in Jason Gallant's and Scott Peacor's labs. Her research explores genomic mechanisms underlying evolutionary adaptations, particularly in seahorses and pipefish. Articles emphasize single-cell RNA sequencing to uncover developmental pathways and comparative genomics to study syngnathid diversification. While no specific awards are listed, her work contributes to the Knight Campus's broader goals in scientific innovation. Healey's academic advising and grant activities are not detailed in the provided text, though her involvement with the Knight Campus Graduate Internship Program suggests mentoring roles. She has been affiliated with labs at the University of Oregon and Michigan State University.

Zhigang Heمشاهده پروفایل

استاد

• Axon Regeneration
• Neural Repair
• Spinal Cord Injury
• +۳ مورد دیگر

Zhigang He is a Professor at Boston Children's Hospital, directing the Viral Core which supports viral vector technologies for academic research. His research focuses on restoring CNS function after spinal cord injury through axon regeneration and synaptic reconnection, addressing critical challenges like axonal guidance and functional synapse formation. He holds a PhD from the University of Toronto and completed postdoctoral training at UCSF under Marc Tessier-Lavigne. His awards include the Klingenstein Fellowship and 2019 Reeve-Irvine Research Medal. Education: PhD, University of Toronto; Postdoctoral Fellowship, UCSF Key Research Areas: Neural repair mechanisms, spinal cord injury recovery, optic nerve regeneration Viral Core Facilities: Offers custom AAV/lentiviral vector production for neuroscience applications Recent articles emphasize axonal regeneration strategies, mechanosensory pathways, and spinal-cortical circuitry. His work bridges molecular mechanisms with clinical translation, exploring combinatorial approaches like gene therapy and rehabilitation training. Over 150 peer-reviewed publications demonstrate leadership in neuroregeneration science.

Frode Lars Jahnsenمشاهده پروفایل

استاد

• Immunology
• Allergy
• Gastroenterology
• +۴ مورد دیگر

Frode Lars Jahnsen is a Professor in the Department of Pathology at the University of Oslo, affiliated with Oslo University Hospital (Rikshospitalet). His research focuses on immune cell biology in gastrointestinal and respiratory systems, particularly studying dendritic cells, T cells, and plasma cells in conditions like celiac disease, inflammatory bowel diseases, and graft-versus-host disease. He utilizes advanced techniques such as single-cell RNA sequencing and spatial transcriptomics to understand immune cell dynamics and interactions. Key research interests include: Role of immune cells in gut health and disease Long-lived plasma cells and microbiota regulation Resident memory T cells in mucosal immunity Immunopathology of transplantation and autoimmunity Recent work highlights developments of tools like Cellsnake for single-cell data analysis and contributions to the Human Gut Cell Atlas. His studies often involve collaborations on translational projects, such as applying immunological insights to clinical management of Crohn's disease and allergy therapies. Labs/Teams: Active in the Department of Pathology's immunology research groups, focusing on gut-related diseases and mucosal immunology.

• Heart regeneration
• Stem cell therapies
• Coronary atherosclerosis
• +۳ مورد دیگر

James Chong is a Professor of Cardiovascular Medicine at the University of Sydney and a practicing cardiologist at Westmead Hospital. He serves as Co-Director of the Centre for Heart Research and Head of the Cardiac Regeneration Laboratory at the Westmead Institute for Medical Research. His expertise spans cardiovascular medicine, stem cell therapies, and cardiac regeneration. He holds advanced qualifications including a PhD, MBBS, and FRACP (Fellow of the Royal Australasian College of Physicians). Research interests focus on heart regeneration, stem cell applications, coronary atherosclerosis, and novel therapies for heart disease. Collaborations include work with Prof Charles Murry at the University of Washington. His work has been published in top journals like Nature and Science Translational Medicine, and he has secured major grants including NHMRC/MRFF Investigator awards. Award highlights include the 2024 Jian Zhou Medal and a Fulbright Scholarship. His research explores mechanisms of cardiac repair, including PDGF and peptide mimetics' roles in scar remodeling. He leads projects on stem cell therapies, multi-omics strategies for heart attack analysis, and enhancing pluripotent stem cell-derived cardiomyocyte engraftment. Notable grants include funding for regenerative therapies, scar modulation via Tropoelastin, and gene therapies for arrhythmias. His lab investigates arrhythmia mechanisms and cardiac fibrosis, with clinical focus on acute heart failure and patient care outcomes post-dissection.