جست‌وجوی استاد و پژوهشگر

Elsa Petitمشاهده پروفایل

مدرس ارشد

• Plant-Microbe Interactions
• Viticulture
• Plant Pathology
• +۷ مورد دیگر

Elsa Petit is a Senior Lecturer in Viticulture and Plant Pathology and Program Coordinator for Horticulture Associate and Bachelor of Science Programs at the Stockbridge School of Agriculture, University of Massachusetts Amherst. She is actively engaged in research, teaching, and extension, focusing on sustainable agriculture and plant-microbe interactions in grape systems. Education: Ph.D. in Plant Pathology, University of California, Davis, 2005 M.S. in Agronomy, Bordeaux, France, 2000 Dr. Petit's research centers on the evolution and ecology of plant-microbe interactions, using grape species in the Northeast U.S. as a model system. Her lab investigates the impact of agricultural management on plant microbiomes, temperature effects on flowering time in wild grapes, and variation in disease resistance to fungal pathogens. She emphasizes sustainable viticulture and climate-resilient agricultural practices. Her recent publications span fungal pathology, molecular ecology, genome evolution, and entomology, reflecting interdisciplinary work with strong implications for plant health and biodiversity. Key themes include fungal disease mechanisms, microbiome dynamics, and genetic adaptation in plant pathogens. Service and Leadership: Leader, MA Extension Grape Production Lead Investigator, NIFA Multistate Project NE1720 (MAS00516): 'Multi-state Coordinated Evaluation of Winegrape Cultivars and Clones' Editor, New England Grape Notes Newsletter Chair, Ad Hoc Committee on Language Proficiency Member, International Studies Council Member, Faculty Senate - General Education Council She teaches courses such as General Plant Pathology, Sustainable Grape Production, and Global Issues in Applied Biology. Her extension work bridges academic research with practical grape growing in Massachusetts, supporting local growers through science-based outreach.

Pascal Chartrandمشاهده پروفایل

استاد

• Molecular Imaging
• Cellular Dynamics of RNA
• Telomerase Biology
• +۳ مورد دیگر

Pascal Chartrand is a Full Professor at the University of Montreal's Faculty of Medicine, Department of Biochemistry and Molecular Medicine. His research focuses on molecular imaging of RNA dynamics, telomerase biology, and mechanisms underlying Myotonic Dystrophy Type 1. Chartrand leads a lab using cutting-edge microscopy and genomic approaches to study RNA trafficking and its role in disease. He has held prestigious awards including the FRQS Research Chair (2015-2019) and multiple FRQS/FCAR scholarships. His work bridges basic science and translational research, with over 60 publications in top journals like Science Advances and Molecular Cell. Key contributions include discovering TERRA's role in telomere regulation and developing tools like CoPixie for tracking telomerase activity. Chartrand collaborates internationally, contributing to biochemistry, cell biology, and RNA medicine fields.

• RNA Biology
• Molecular Biology
• Genetics
• +۶ مورد دیگر

Dr. Éric Lécuyer is a Professor and Researcher at the Montreal Clinical Research Institute (IRCM) , affiliated with the University of Montreal (Department of Biochemistry and Molecular Medicine) and McGill University . His research focuses on understanding RNA subcellular localization mechanisms and their roles in cellular functions and disease. Key areas include mRNA trafficking in cell polarity, genomic stability, and the impact of RNA localization disruptions in neurodegenerative diseases and cancer. His work combines Drosophila genetics, high-resolution imaging, and functional genomics. Dr. Lécuyer collaborates with the ENCODE consortium to study RNA-binding proteins (RBPs) in human cells, using biochemistry, genetics, and bioinformatics. Recent grants include CIHR funding for projects on mRNA localization in mitosis regulation and neurodegenerative disorders. His lab employs advanced platforms such as microscopy and RNA-Seq. Notable advisees include Dr. Ashley Chin, who defended her thesis in 2022. The lab’s team includes researchers like Dr. Catherine Ménard and bioinformatics analyst Julie Cardin. Dr. Lécuyer’s lab is part of IRCM’s multidisciplinary environment, leveraging platforms like molecular biology, flow cytometry, and disease modeling. His research bridges basic science and clinical applications, aiming to uncover therapeutic targets through RNA biology.

Zachary T. Ballمشاهده پروفایل

استاد

• Protein Chemistry
• Transition-Metal Catalysis
• Chemical Biology
• +۳ مورد دیگر

Zachary T. Ball is a Professor of Chemistry at Rice University, leading the Ball Research Group. His work focuses on the intersection of protein chemistry and transition-metal catalysis, with contributions to medicinal chemistry, bioimaging, and synthetic methodology. He earned his A.B. in Chemistry from Harvard University (1999) and Ph.D. from Stanford University (2004), followed by a Miller Fellowship at UC Berkeley (2004–2006). His research emphasizes selective chemical reactions in complex biological environments, particularly using secondary structure and local conformation for reactivity control. Current projects include designing transition-metal complexes for chemical biology and developing antibody-drug conjugates. Collaborations, such as with the Tour lab on plasma-based antibacterial materials, highlight interdisciplinary innovation. Key research areas include Protein modification with transition metals Metallo-therapeutic agents Bioorthogonal chemistry Dynamic covalent systems Recent publications (2021–2024) explore pyroglutamate-selective reactivity, boronic acid reagents, and STAT3 signaling in cancer. His work bridges organic synthesis and biological applications, with potential in drug delivery and diagnostic tools. While no specific awards are listed, his contributions to chemical biology are widely recognized through publications and collaborations.

Dee Scaddenمشاهده پروفایل

مدرس

• RNA Editing
• Stress Responses
• Molecular Biology
• +۳ مورد دیگر

Dr. Dee Scadden is a Lecturer in the Department of Biochemistry at the University of Cambridge, affiliated with the School of the Biological Sciences (SBS). Her work focuses on teaching innovation, digital learning, and RNA editing mechanisms in cellular stress responses. She has pioneered online teaching resources, including animated films and inclusive learning strategies, and led the implementation of Inspera Assessment for exams. Her research investigates the role of hyper-edited dsRNA in mammalian cells, particularly its interaction with stress granules and effects on gene expression. Research Interests: RNA Editing, Stress Responses, Molecular Biology. Her studies explore how adenosine-to-inosine editing by ADAR proteins impacts dsRNA structure and function, with implications for cellular stress and disease. She has also contributed to understanding Z-DNA-binding proteins in stress granules. Awards: Pilkington Teaching Prize (2021) Technology Enabled Learning Prize in STEM (2019) Biochemical Society Teaching Excellence Award (2017) Teaching & Innovation: Developed online practical sessions, animated educational content, and Universal Design for Learning frameworks. Collaborated on pandemic-era teaching adaptations and digital exam platforms.

Heiner Kuhlمشاهده پروفایل

پژوهشگر

• Molecular Fish Physiology
• Genetics and Evolution of Fish
• Sex Determination Mechanisms
• +۴ مورد دیگر

Dr. Heiner Kuhl is a Scientific Staff member in the Department of Fish Biology, Fisheries and Aquaculture at the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB Berlin). His research focuses on molecular fish physiology, genetics, and evolution, particularly in sex determination, genome analysis, and aquatic species adaptation. Affiliation: IGB Berlin, Department of Fish Biology, Fisheries and Aquaculture Role: Researcher His research spans comparative genomics, polyploidy, and biodiversity genomics, with a strong emphasis on aquatic vertebrates. Recent projects highlight his work on sex chromosome evolution and genome stability in invasive species. Dr. Kuhl has contributed to major publications in journals like Nature Communications , Molecular Ecology , and Philosophical Transactions of the Royal Society . His work often involves interdisciplinary collaborations, particularly in genome assembly and evolutionary biology.

• Cognitive Disorders
• Neuroscience
• Neurology
• +۵ مورد دیگر

Dr. Nicholas Alonzo Frost is a board-certified neurologist and Assistant Professor in Neurology and Neurobiology with a focus on understanding the mechanisms underlying cognitive and memory disorders. His research explores how complex behaviors, particularly social interactions, are encoded within the prefrontal cortex and how these processes are disrupted in disease. University of Maryland School of Medicine - M.D., Ph.D. University of California, San Francisco - Residency and Fellowship His clinical expertise includes Alzheimer's Disease and Cognitive Disorders, with a patient rating of 4.9/5. Dr. Frost employs advanced imaging and transcriptomic techniques to investigate heterogeneous neuronal populations and their role in behavioral information encoding. 2024: Thalamocortical organoids for modeling neuropsychiatric disorders 2024: Single-nuclei RNA-seq for social interaction analysis 2023: Prefrontal cortex socioemotional encoding

• Non-viral drug delivery
• Polymeric nanoparticles
• Extracellular vesicles
• +۳ مورد دیگر

Gijung Kwak is a Postdoctoral Research Fellow at the University of Maryland School of Medicine (since 2023) and previously at the Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine (2020-2023). He specializes in advanced drug delivery systems, focusing on non-viral gene delivery , polymeric nanoparticles , and extracellular vesicles for targeting brain, lung, and ocular tissues. B.S., INHA University (2015) Ph.D., Korea University (2020) Visiting Researcher, UC Berkeley (2018-2019) His research spans critical areas in translational nanomedicine, including RNAi-based cancer therapies , bioreducible gene delivery platforms , and sustained release formulations for wound healing. Recent work explores synergistic tumor suppression, ocular gene delivery, and dual-arm strategies for brain tumor targeting. Publication trends reveal expertise in pDNA/mRNA/RNAi delivery , polymer nanotechnology , and macrophage modulation . Collaborations include leading researchers like Prof. Jung Soo Suk and Phillip B. Messersmith.

• CRISPR-Cas9 Gene Editing
• Genome Engineering
• Immunotherapy
• +۲ مورد دیگر

凌嘉鴻 is a Researcher at the Institute of Biochemistry, Academia Sinica , specializing in CRISPR-Cas9 gene editing, immunotherapy, and DNA repair mechanisms. His work focuses on enhancing natural killer (NK) cell therapies, developing adenovirus vectors for DNA delivery, and unraveling CRISPR-Cas9-mediated DNA double-strand break repair processes. Ph.D., Microbiology, University of Illinois at Urbana-Champaign Postdoc, University of California, Berkeley His recent research explores CRISPR-Cas9 applications in genomic stability , immune cell engineering , and viral therapy . Key publications include studies on NK cell cytotoxicity enhancement and DNA-free CRISPR gene editing. He has also contributed to structural analyses of Cas9 endonucleases and off-target profiling of CRISPR systems.

Changrui Xiaoمشاهده پروفایل

استادیار

• Genomics
• Neurology
• Rare Diseases
• +۳ مورد دیگر

Changrui Xiao, MD, serves as an Assistant Professor in the Department of Neurology at the University of California, Irvine (UCI) School of Medicine, where he specializes in genomic approaches to diagnosing rare neurological disorders through clinical and research initiatives. His research spans genomics, neurology, and rare diseases with emphasis on neurodevelopmental disorders and clinical genomic testing. Key interests include novel gene discovery, variant interpretation frameworks, and leveraging advanced sequencing technologies to improve diagnostic yield for Mendelian conditions. His work addresses critical gaps in reporting variants in candidate genes and translating genomic findings into clinical practice. Recent publications (2024-2025) demonstrate consistent focus on genomic diagnostics for undiagnosed rare diseases, featuring telehealth evaluation methods, repeat expansion disorder discovery, and non-coding variant analysis. His research frequently involves large-scale consortia data and emphasizes practical implementation of genomic technologies in clinical settings. Dr. Xiao contributes to major NIH-funded initiatives including the Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium and the Undiagnosed Diseases Network. His work is supported by multiple NHGRI grants (U01 HG011745, U24 HG011746, U01 HG011762) focusing on genomic infrastructure development and diagnostic pathway optimization. He actively participates in collaborative efforts integrating clinical expertise with genomic research through platforms like Matchmaker Exchange and ClinVar, emphasizing systematic data sharing to accelerate gene validation and improve diagnostic outcomes for rare disease patients.

Alper Aytekinمشاهده پروفایل

استادیار

• Colorectal Cancer
• Breast Cancer
• MicroRNA (miRNA) Research
• +۴ مورد دیگر

Alper Aytekin , an Assistant Professor at the Faculty of Health Sciences of Gaziantep University , specializes in Colorectal Cancer , Breast Cancer , and MicroRNA (miRNA) Research . His work bridges Surgical Oncology , Medical Genetics , and Molecular Biology , focusing on biomarker discovery and diagnostic innovation. Education: Medical Specialization (2008-2014) and Türkiye Licence (2001-2008) at Gazi University and Gaziantep University Key Research Areas: miRNA expression in gastrointestinal and breast cancers, surgical techniques for hydatid cyst complications, and diagnostic scoring systems His recent publications highlight the utility of 68Ga-FAPI PET/CT over traditional methods in cancer imaging, novel miRNA biomarkers for Colorectal and Breast Cancer , and surgical innovations for Biliary Fistulas . He has contributed to 38 publications and collaborated on national and international projects. Projects: Investigated miRNA profiles (2021-2023), TERT promoter mutations (2017-2018), and chemiluminescence bile duct imaging (2020-2021) Theses Supervised: Over 12 theses and 6 doctoral dissertations, including studies on Acute Appendicitis , Parathyroid Hormones , and Colorectal Cancer His work has been presented at 49 conferences, including the 33rd National Urology Congress (2024) and International Zeugma Congress (2023), with a focus on translational research and clinical applications.

• Biochemistry
• Molecular Biology
• Cancer Biology
• +۵ مورد دیگر

Kellie Dean is a College Lecturer, Principal Investigator, and Postgraduate Director at the School of Biochemistry & Cell Biology at University College Cork (UCC). A biochemist with expertise in RNA biology and cancer research, she leads a group focused on non-coding RNAs, RNA-binding proteins, and RNA-protein complexes in cancer pathology. Her academic journey includes a PhD from the University of North Carolina at Chapel Hill, postdoctoral work in Germany and the USA, and a transition to full-time academia in Ireland since 2015. Education : BSc in Chemistry (Indiana University of Pennsylvania), PhD in Biochemistry and Biophysics (UNC Chapel Hill) Key Collaborations : Howard Hughes Medical Institute, Science Foundation Ireland (SFI), Irish Research Council, University of California-Davis Her research spans RNA biology , cancer genomics , and bioinformatics , with a focus on long non-coding RNAs (lncRNAs) in ductal carcinoma in situ (DCIS) and ovarian cancer. She investigates their functional roles, diagnostic potential, and the phase separation of RNA-protein assemblies. Her work leverages ribosome profiling data to develop algorithms for micropeptide prediction in cancer immunotherapy vaccines. Her publications highlight trends in cancer RNA biology , including lncRNAs, translational regulation, and computational methods for RNA analysis. Key journals include Cancers , Frontiers in Cell and Developmental Biology , and BMC Cancer . Grants from the Science Foundation Ireland and Irish Research Council support her projects. Professional Affiliations : Member of Irish and European Associations for Cancer Research Member of the RNA Society and Biochemical Society Co-coordinator of UCC Cell EXPLORERS outreach program

• Neuroscience
• Neuroplasticity
• Stress Biology
• +۳ مورد دیگر

Teresa A Milner is the Thomas H. Meikle Professor in Medical Education and Administration and Professor of Neuroscience at the Weill Cornell Medical College , Brain and Mind Research Institute since 2012. Her research focuses on neuroplasticity, sex hormone receptor dynamics, and stress-related neurodegenerative mechanisms. Fields of Interest : Neuroscience, Estrogen Receptor Signaling, Neuroinflammation, Hypertension Neurobiology, Neuroplasticity, Medical Education Research Themes explore how estrogen receptors modulate synaptic plasticity, neuroinflammatory responses in Alzheimer's disease models, and stress-induced alterations in opioid receptor distribution. Recent work examines perimenopausal transitions in neurovascular dysfunction and hippocampal inflammation. Publications (2022-2025) reveal novel insights into TNFα-induced oxidative stress, ERβ agonist effects on NMDA receptors, and single-cell splicing patterns in brain aging and disease. Collaborative studies map sex differences in angiotensin II hypertension and opioid system plasticity. Scientific Award : Thomas H. Meikle Professorship in Medical Education (2025)

Timothy A. Ryanمشاهده پروفایل

استاد

• Synaptic Function
• Neuronal Metabolism
• Neurodegenerative Diseases
• +۳ مورد دیگر

Timothy A. Ryan is a Professor of Biochemistry and Biophysics and a Professor of Biochemistry in Anesthesiology at Weill Cornell Medical College. His research focuses on synaptic function, neuronal metabolism, and mechanisms underlying neurodegenerative diseases like Parkinson's, with an emphasis on calcium signaling, synaptic vesicle trafficking, and energy dynamics. McGill University - B.Sc. (1981) Cornell University - M.S. (1986) Cornell University - Ph.D. (1989) Ryan’s work explores the interplay between synaptic activity and metabolic demands, particularly in conditions like Parkinson’s disease. His studies investigate how organelles such as mitochondria and the endoplasmic reticulum regulate synaptic efficiency and resilience. Recent publications highlight his focus on ATP monitoring, calcium signaling, and lipid metabolism in synaptic health. Key collaborations include researchers like Mukesh Kumar and Hugh C. Hemmings. Funding sources include the National Institute of Neurological Disorders & Stroke (NINDS) and SPARK NS, Inc.

Sami Barmadaمشاهده پروفایل

دانشیار

• Neurodegenerative Diseases
• RNA Biology
• ALS (Amyotrophic Lateral Sclerosis)
• +۵ مورد دیگر

Sami Barmada is an Associate Professor of Neurology and the Angela Dobson and Lyndon Welch Research Professor at the University of Michigan Medical School, where he also directs the Brain Bank. His research focuses on molecular mechanisms underlying amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), with particular emphasis on RNA stability, RNA-binding proteins, and neurodegeneration pathways. His laboratory employs an interdisciplinary approach combining automated fluorescence microscopy, computer science, genome engineering, and bioinformatics to investigate protein and RNA metabolism in neurodegenerative diseases. Research interests span TDP-43 pathology, stress granule dynamics, autophagy, and repeat expansion disorders, with the goal of identifying therapeutic targets for ALS/FTD. The lab utilizes human neuron models and high-content screening to dissect disease mechanisms. Analysis of recent publications reveals strong focus on TDP-43 autoregulation, RAN translation mechanisms, nuclear transport defects, and sex-specific clinical phenotypes in FTD. Key themes include RNA processing abnormalities, protein quality control failures, and the role of nucleocytoplasmic transport deficits in neurodegeneration. Barmada actively participates in diversity, equity, and inclusion initiatives, having completed MORE Mentor Training, Implicit Bias Training, Anti-Racism Training, and Gender Bias Training. His lab explicitly celebrates diversity as fundamental to scientific progress. The Barmada Lab comprises postdoctoral fellows, graduate students, technicians, research specialists, software engineers, and undergraduates working collaboratively in the A. Alfred Taubman Biomedical Sciences Research Building. The team emphasizes real-time visualization of neurodegeneration to distinguish causal disease mechanisms from secondary effects.