جستجوی استاد راهنمای دانشگاهی

• Water Quality
• Microbial Source Tracking
• Waterborne Pathogens
• +۳ مورد دیگر

Marc Habash is an Associate Professor at the School of Environmental Sciences, University of Guelph. His work focuses on microbial interactions in environmental systems, particularly pathogen detection, microbial biofilms, and water quality. He holds a BSc in Cellular and Molecular Biology from the University of Toronto, an MSc in Microbiology and Immunology from the University of Western Ontario, and a PhD in Environmental Biology from the University of Guelph. Research interests include molecular and culture-based detection of waterborne pathogens, microbial source tracking using Bacteroidales spp., and biofilm formation studies involving probiotics. Collaborative efforts examine proteomic analysis via mass spectrometry techniques. His lab is located in the Edmund C. Bovey Building (Room 3238). Publications emphasize environmental microbiology applications: from yeast tolerance mechanisms to advanced PCR methods for microbial viability quantification. Recent work explores bacterial surface dynamics, insect pest diapause induction, and enzymatic dehalogenation processes. Research consistently bridges fundamental microbiology with practical environmental monitoring solutions. No scientific awards are listed. Advising and grants sections remain unpopulated in available records. His interdisciplinary approach connects environmental engineering, molecular biology, and ecological systems analysis.

• Antibiotic Resistance
• Microbial Biotechnology
• Bacterial Physiology
• +۳ مورد دیگر

Prof. Dr. Susanne Gebhard is a Full Professor of Molecular Biotechnology at the Institute for Molecular Physiology , Johannes Gutenberg University (JGU) Mainz, Germany, since 2023. Her career spans international institutions, including postdoctoral work in New Zealand and the UK, and a permanent research and teaching position at the University of Bath. She focuses on bacterial physiology, particularly antibiotic resistance mechanisms and microbially induced calcite precipitation for sustainable biotechnology applications. Education: Abitur (1996), University Degree (2003), PhD in Microbiology (2006, University of Otago, New Zealand), Habilitation (2014) Research Interests: Her work bridges two major themes: Antibiotic Resistance : Investigating how bacteria detect antibiotics and regulate resistance pathways, with implications for novel therapeutic strategies. Microbial Biomineralization : Exploring bacterial mineralization processes to reduce cement usage in construction, addressing CO 2 emissions through Solibacillus silvestris and related species. Publications & Collaborations highlight her expertise in Bacillus subtilis , Pseudomonas , and Neisseria systems, alongside contributions to journals like Nature Communications , Cell Reports , and Environmental Microbiology . She frequently collaborates with labs in Oxford, Cologne, and Australia. Scientific Engagement includes: Senior Editor for the Microbiology journal Deputy Spokesperson for the 'Regulation' specialist group of the Association for General and Applied Microbiology Active participation in international conferences and EMBO workshops Lab & Leadership : She leads the Gebhard Lab at JGU Mainz, mentoring students and postdocs while emphasizing interdisciplinary collaboration. Her hobbies include horseback riding, gardening, and exploring the intersection of science and sustainability.

Robert T. Clubbمشاهده پروفایل

استاد

• Biochemistry
• Biophysics
• Structural Biology
• +۹ مورد دیگر

Robert T. Clubb is a Professor in the Department of Biochemistry at the University of California, Los Angeles (UCLA), where he leads an active research laboratory focused on host-pathogen interactions and bacterial pathogenesis. His work bridges biochemistry, biophysics, and structural biology to understand how bacterial pathogens acquire essential nutrients and cause disease. Dr. Clubb's research focuses on three main areas: pilus assembly in bacterial pathogens, host-pathogen interactions specifically examining heme-iron acquisition, and chemical biology approaches to antibiotic discovery. His laboratory employs highly interdisciplinary methods including structural biology, biophysical, cellular, and -omics technologies to uncover molecular mechanisms that enable microbial pathogens to cause disease, with the ultimate goal of discovering new antibiotics and developing innovative biotechnological tools. His recent publications demonstrate a strong focus on understanding how Staphylococcus aureus and other bacterial pathogens extract heme-iron from human hemoglobin, with particular attention to the IsdH and IsdB receptor proteins. This work has significant implications for developing novel anti-infective agents against methicillin-resistant Staphylococcus aureus (MRSA) and other multidrug-resistant Gram-positive bacteria, as evidenced by his laboratory's high-throughput screening approaches for identifying potential therapeutic compounds. Nikki Cheung was awarded a Science Olympiad Fellowship Kylie Cheng was awarded a CMB Fellowship Andrew Goring was awarded a UCLA Dissertation Year Fellowship Multiple students have received UCLA Whitcome Fellowships Dr. Clubb has successfully mentored numerous graduate students, with recent lab members including Esmeralda Corrales, Nikki Cheung, Allen Takayesu (winner of best poster at the Protein Society Meeting), Kylie Cheng, Andrew Goring, Christine Minor, Reece Pawlacyk, and Dr. Chris Sue who completed his PhD in biochemistry. His laboratory has been supported by multiple NIH grants including R01 GM103479, R01 AI052217, and S10 RR028893. The Clubb Laboratory maintains state-of-the-art facilities in Boyer Hall (rooms 620, 621, and 660) at UCLA, equipped for advanced structural biology, biophysical, and microbiological research. The team collaborates extensively with researchers across disciplines to tackle fundamental questions in bacterial pathogenesis and antibiotic resistance, with ongoing projects investigating heme acquisition mechanisms in multiple bacterial species.

Lori Burrowsمشاهده پروفایل

استاد

• Antimicrobial resistance
• Bacteriology
• Biochemistry
• +۶ مورد دیگر

Professor Lori Burrows is a distinguished microbiologist at McMaster University's Faculty of Health Sciences, Department of Biochemistry & Biomedical Sciences. She serves as the Associate Director (Partnerships and Outreach) of McMaster University's Michael G. DeGroote Institute for Infectious Diseases Research. As a Fellow of the American Academy of Microbiology, she is recognized as an international expert in bacterial pathogenesis, particularly in the study of type IV pili and their role in bacterial virulence. Dr. Burrows' primary research interests focus on the structure, function, and regulation of type IV pili (T4P), which are ubiquitous bacterial virulence factors used for adherence, DNA uptake, biofilm formation, and twitching motility. Her laboratory primarily uses the opportunistic pathogen Pseudomonas aeruginosa as a model system to investigate pilin repertoire (relevant to vaccine design), pilin glycosylation systems involved in bacteriophage defense, structure-function of the pilus assembly system, and the complex regulation underlying T4P function. Additionally, her group studies biofilm formation, particularly the stimulation of biofilm development by sub-inhibitory antibiotic concentrations and the exploitation of this stimulation phenotype to discover new antimicrobials for multidrug-resistant gram-negative bacteria. Dr. Burrows' research program is robustly funded by multiple prestigious sources including the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada, the Canadian Glycomics Network, the Ontario Research Fund, and industrial support. Her publication record is impressive, with over 120 peer-reviewed papers, reviews, and book chapters, and an h-index of 49. Her recent work demonstrates continued leadership in understanding bacterial pathogenesis mechanisms, antibiotic resistance, and novel approaches to antimicrobial development. Fellow of the American Academy of Microbiology Dr. Burrows serves on the Editorial Boards of the Journal of Bacteriology (ASM), the Journal of Biochemistry (ASBMB), and ACS Infectious Diseases, demonstrating her significant contributions to the scientific community. Her laboratory, the Burrows Lab, is affiliated with both the Michael G. DeGroote Institute for Infectious Disease Research and the David Braley Centre for Antibiotic Discovery at McMaster University, positioning her research at the forefront of infectious disease and antibiotic discovery.

• Molecular Microbiology
• Bacterial Physiology
• Flagellar Biology
• +۳ مورد دیگر

Prof. Dr. Marc Erhardt is a Full Professor of Molecular Microbiology at Humboldt-Universität zu Berlin, Germany, and a Max Planck Fellow at the Max Planck Unit for the Science of Pathogens. His academic career includes prior roles as Associate Professor (W2) at Humboldt-Universität and a Principal Investigator at the Helmholtz Centre for Infection Research. He holds a PhD from the University of Konstanz (summa cum laude) and completed postdoctoral work at Université de Fribourg and the University of Heidelberg. His research focuses on bacterial physiology, flagellar biology, and type III secretion systems, with notable contributions to understanding flagellar assembly mechanisms and bacterial motility. Erhardt has received prestigious awards including the ERC Consolidator Grant (2019) and the VAAM Forschungspreis (2018). His work spans structural biology, pathogen-host interactions, and synthetic biology tools for microbial systems. Education: PhD in Molecular Microbiology (2011), University of Konstanz Diploma in Biology (2006), University of Ulm, Konstanz, and University of Utah Research interests include the molecular mechanisms of flagellar assembly, bacterial motility regulation, and the interplay between bacterial physiology and pathogenicity. Key achievements include discoveries on flagellin incorporation mechanisms, anti-phage defense systems, and CRISPRi-mediated bacterial regulation. Erhardt's lab (AG Bacterial Physiology) employs advanced microscopy, structural biology, and synthetic biology approaches to explore bacterial nanomachines and infection strategies. His research has led to over 60 publications in journals like Cell , Nature Communications , and PLOS Biology . Awards & Grants: ERC Consolidator Grant (2019) Helmholtz Young Investigator Grant (2013–2017) Marie Curie International Fellowship (2012–2013) His research group develops novel tools for studying bacterial systems, including fluorescent markers for Gram-negative bacteria and regulatory systems for synthetic biology. Current projects address flagellar dynamics, microbiota interactions, and the structural basis of bacterial pathogenesis.

P. Lynne Howellمشاهده پروفایل

استاد

• Microbial Pathogenesis
• Biofilm Formation
• Structural Biology
• +۴ مورد دیگر

Dr. P. Lynne Howell is a Senior Scientist at the Department of Biochemistry , affiliated with the University of Toronto. Her research focuses on microbial pathogenesis, structural biology, and biofilm formation, particularly in Pseudomonas aeruginosa . She has developed novel therapeutic strategies targeting bacterial and fungal infections using glycoside hydrolases and small-molecule modulators. Role: Senior Scientist, Professor Department: Biochemistry University: University of Toronto Research Interests: Dr. Howell's lab investigates molecular mechanisms of biofilm formation, exopolysaccharide biosynthesis, and type IV pilus assembly in pathogenic microbes. They combine structural biology, biophysics, and microbiology to design therapies for chronic infections. Scientific Awards: Canada Research Chair in Structural Biology (2013–2020) Canada Research Chair in Structural Biology (2006–2013) CIHR Investigator Research Award (2001–2006) SERC Studentship Research Award (1983–1986) Students: She supervises graduate students including Natalie Bamford, Andreea Gheorghita, Lindsey Marmont, Matthew McCallum, Erum Razvi, and Greg Whitfield. Labs & Teams: The Howell Lab collaborates with structural biology and microbiology groups, focusing on microbial biofilm therapeutics. They utilize advanced technologies like nuclear magnetic resonance and X-ray crystallography.

Zemer Gitaiمشاهده پروفایل

استاد

• Bacterial Cell Biology
• Cytoskeletal Dynamics
• Microbial Pathogenesis
• +۸ مورد دیگر

Zemer Gitai is the Edwin Grant Conklin Professor of Biology and Professor of Molecular Biology at Princeton University, where he leads the Gitai Lab in the Department of Molecular Biology. His research focuses on the fundamental mechanisms of bacterial cell biology, including cytoskeletal dynamics, cellular polarity, and morphogenesis. Institution: Princeton University Department: Department of Molecular Biology Lab: Gitai Lab Contact: zgitai@princeton.edu Gitai’s research explores how bacteria achieve complex subcellular organization and how these processes contribute to pathogenesis and antibiotic resistance. His lab uses interdisciplinary methods including genetics, biochemistry, live-cell imaging, genomics, and computational modeling to study bacterial self-organization, microbe-host interactions, and novel antibiotic discovery. A central theme is understanding how bacterial cytoskeletal proteins like MreB regulate cell shape and chromosome segregation. His recent publications (2022–2024) reveal trends in mechanosensing , trans-kingdom signaling , and transgenerational epigenetic inheritance mediated by bacterial small RNAs. His work spans model organisms like Caulobacter crescentus , Pseudomonas aeruginosa , and C. elegans , uncovering how bacteria sense surface stiffness, regulate nitrogen metabolism to influence host behavior, and dynamically control pilus-based motility. Scientific honors include: NIH Pioneer Award (2015) Gitai actively mentors students and postdoctoral researchers, with several advisees contributing to high-impact publications. His lab has developed innovative tools such as MitoRiboSeq for monitoring mitochondrial translation and M3-Seq for single-cell microbial transcriptomics. He also investigates how antibiotics can be used to probe bacterial cell biology and combat resistance through anti-virulence strategies. The Gitai Lab fosters collaborative research with Princeton colleagues across disciplines.

• Structural Biology
• Biochemistry
• Metalloproteins
• +۳ مورد دیگر

Dr. Mark Banfield is a structural biologist at Newcastle University , focusing on metalloprotein structure-function relationships and bacterial pathogenesis. His work spans metal coordination in cupredoxins, ferric binding in cyanobacteria, and virulence protein architecture in Streptococcus pyogenes and Escherichia coli . Key research areas: Structural Biology, Metalloproteins, Bacterial Pathogenesis, Protein Engineering, Molecular Biology, Metal Homeostasis Notable collaborations: with Wendy Smith, Christopher Dennison, Paul Race, and others on metal binding and bacterial virulence His structural studies on pilus subunits and sortase A provide insights into host-pathogen interactions. Recent work on loop length and aromatic interactions highlights design principles for metalloprotein active sites. Current efforts include exploring phosphorylation effects in virulence proteins and metal specificity in folding environments.

C. Julie Changمشاهده پروفایل

پژوهشگر

• Molecular Microbiology
• Bacterial Pathogenesis
• Oral Microbiology
• +۵ مورد دیگر

Dr. C. Julie Chang is a Full-Time Faculty Researcher at the University of California, Los Angeles specializing in molecular microbiology with over 15 years of expertise in bacterial pathogenesis and oral biofilm development. Her work focuses on the role of bacterial cell surface virulence factors in polymicrobial interactions during periodontitis, utilizing biochemical and genetic approaches to study Gram-positive pathogens. Education: B.S. in Biology, Tunghai University, Taichung, Taiwan, 1984 Ph.D. in Microbiology, Texas A&M University, College Station, Texas, 1994 Chang's research integrates protein biochemistry and engineering to innovate therapeutic treatments for oral diseases. She investigates sortase-mediated pilus assembly mechanisms in pathogens like Corynebacterium diphtheriae and Fusobacterium nucleatum , revealing how bacterial surface structures drive biofilm formation and host tissue destruction in periodontitis. Her work bridges fundamental molecular mechanisms with clinical applications for dental disease prevention. Analysis of her 35+ publications shows consistent focus on Gram-positive bacterial surface assembly, with recent work expanding into oxidative stress defense systems and polymicrobial virulence networks. Key trends include structural characterization of sortase enzymes, identification of novel virulence determinants, and development of therapeutic strategies targeting bacterial adhesion mechanisms. Scientific Awards: U.S. Patent No. 5,777,078: Triggered Pore Forming Agents Chang has supervised numerous graduate students and postdoctoral researchers while managing laboratory operations for the Ton-That research group. She has led collaborative projects resulting in high-impact publications in journals including Proceedings of the National Academy of Sciences , with research funded through institutional grants focused on oral bacterial pathogenesis. Her laboratory employs biochemical, genetic, and structural methodologies to dissect bacterial surface assembly pathways critical for polymicrobial biofilm development in the oral cavity.

• Microbial Pathogenesis
• Structural Biology
• Molecular Microbiology
• +۴ مورد دیگر

Dr. Shoichi Tachiyama is a Research Fellow in Microbial Pathogenesis at Yale School of Medicine. His research focuses on understanding bacterial pathogenesis mechanisms, particularly in Shigella and Helicobacter pylori. He investigates the structural and functional aspects of bacterial secretion systems and flagellar motors using cryo-electron microscopy and biophysical approaches. He earned his Ph.D. in Biochemistry and Biophysics from the University of Kansas (2020), followed by postdoctoral training in Dr. Jun Liu’s lab at Yale. His work explores the molecular architecture of the Type III Secretion System (T3SS) in Shigella and the high-torque flagellar motor of Helicobacter pylori. Collaborations with Drs. William Picking (University of Kansas) and Timothy Hoover (University of Georgia) have advanced his studies on flagellar motor proteins and outer membrane dynamics. Key research interests include host-pathogen interactions, bacterial motility mechanisms, and structural biology of pathogenic proteins. His recent studies highlight the structural basis of flagellar motor components and their roles in bacterial pathogenicity.

Matthew Francisمشاهده پروفایل

استاد

• Bacterial pathogenesis
• Bacterial physiology
• Infection biology
• +۵ مورد دیگر

Matthew Francis is a Professor at Umeå University's Department of Molecular Biology, where he serves as Head of Undergraduate Education. His research laboratory investigates bacterial physiology and pathogenesis, with a particular focus on Yersinia pseudotuberculosis and its mechanisms for preserving biological function in toxic environments. Francis maintains an active research program with international collaborations and has published extensively in high-impact microbiology journals. Education: BSc in Microbiology, Genetics and Biochemistry from Adelaide University (1990) PhD in Bacterial Pathogenesis from Adelaide University (1997) Postdoctoral training at Umeå University (1997-2001) Professor Francis's research focuses on bacterial stress response mechanisms, particularly the Cpx envelope stress system and its role in regulating virulence factors in pathogenic bacteria. His work examines how bacteria like Yersinia pseudotuberculosis utilize type III secretion systems to interact with host cells, avoid immune responses, and establish infection. His laboratory has identified key regulatory networks that function as molecular switches allowing bacteria to adjust their physiological state according to environmental conditions. Analysis of his recent publications reveals a consistent research trajectory examining bacterial secretion systems, stress responses, and antimicrobial resistance mechanisms. His work spans fundamental molecular mechanisms of bacterial pathogenesis to applied research on antibiotic resistance dissemination. The Francis laboratory's publications frequently appear in leading microbiology journals including npj Antimicrobials and Resistance, Molecular Microbiology, and Frontiers in Cellular and Infection Microbiology. As Head of Undergraduate Education in the Department of Molecular Biology, Professor Francis has been involved in teaching bacterial infection biology, genetics, and gene expression for many years. His research program has received support from the Swedish Research Council, including a junior investigator starting grant that enabled him to establish his independent research team in 2002. The Francis Laboratory operates from facilities at 6K and 6L, Hospital Area, 6L-145, Umeå University. The research group maintains a strong interest in understanding bacterial physiology and pathogenesis, with particular emphasis on how pathogens survive host immune responses and environmental stresses. Their work aims to identify critical bacterial survival mechanisms that could serve as targets for novel antimicrobial therapies.

Alyson M Hockenberryمشاهده پروفایل

استادیار

• Infectious Disease
• Systems Biology
• Bacterial Pathogenesis
• +۲ مورد دیگر

Dr. Alyson M. Hockenberry is an Assistant Professor of Microbiology and Immunology at Loyola University Chicago's Stritch School of Medicine. She holds a Ph.D. from the University of Arizona and completed postdoctoral training at ETH Zurich. Her research employs quantitative and systems biology approaches to study bacterial pathogenesis and host-microbe interactions. Research interests focus on: Quantitative analysis of infectious disease mechanisms Salmonella pathogenesis and evolution Microbiota-derived metabolite effects on pathogens Secretory IgA function in mucosal immunity Microbial community dynamics Publications reveal interdisciplinary approaches combining microbiology, immunology, and systems biology. Recent work explores how secretory IgA structures constrain Salmonella mobility and how microbial metabolites influence pathogen behavior at single-cell resolution. Current projects investigate bacterial population heterogeneity during infection and microbial community resilience through minority-driven growth patterns.

• Biochemistry
• Biophysics
• Structural Biology
• +۴ مورد دیگر

Frederick Dahlquist is a Distinguished Professor and Chair of the Department of Molecular, Cellular & Developmental Biology at the University of California, Santa Barbara (UCSB). He holds a joint appointment with the MCDB Department and has been affiliated with UCSB since 2004. His research focuses on protein structure-function relationships, bacterial chemotaxis, and signal transduction mechanisms, primarily using nuclear magnetic resonance (NMR) spectroscopy. Education: Dr. Dahlquist earned his Ph.D. in Chemistry from the California Institute of Technology (Caltech) in 1969. He was a Miller Research Fellow at the University of California, Berkeley, under Daniel E. Koshland, Jr., before joining the faculty at the University of Oregon. He transitioned to UCSB in 2004. Research Interests: His lab investigates how protein dynamics and structure influence function, particularly in bacterial chemotaxis systems. Key projects include studying signal transduction pathways in E. coli , the role of Che proteins (CheY, CheA, CheZ), and NMR-based analyses of protein aggregation and interactions. Collaborations with other UCSB groups explore intrinsically unstructured proteins and nucleic acid methylation pathways. Publications: His work spans over five decades, with recent contributions on bacterial flagellar motors, chemotaxis adaptation enzymes, and bioelectrochemical systems. Key themes include protein dynamics, enzyme regulation, and structural biology. Advising: While no formal student list is provided, his publications frequently include graduate students and postdocs as co-authors. Collaborations involve interdisciplinary teams across departments. Labs/Teams: His research integrates with UCSB’s Molecular Biology Institute and Chemistry Department, leveraging advanced NMR facilities and computational modeling.

• Membrane Protein Structural Biology
• Bacterial Pathogenesis
• ABC Transporters
• +۸ مورد دیگر

Konstantinos Beis is a Research Professor in Membrane Protein Structural Biology at Imperial College London's Department of Life Sciences, part of the Faculty of Natural Sciences. His research focuses on understanding bacterial pathogenesis and drug resistance mechanisms, particularly through the structural analysis of membrane proteins, ABC transporters, and antibacterial peptides. He holds affiliations with the Centre for Structural Biology, Research Complex at Harwell, and the Membrane Receptor Network. His work employs advanced structural biology techniques such as cryo-EM, X-ray crystallography, and biophysical methods like PELDOR/EPR and smFRET. Key research themes include the structural basis of drug resistance, the mechanism of ABC transporters, and the development of novel antibacterial strategies. Beis collaborates with institutions like Diamond Light Source Ltd and has contributed to studies on Klebsiella pneumoniae, antimicrobial peptides, and conjugation systems in bacteria. His publications span over two decades, with recent work emphasizing structural insights into transporters, antibiotic resistance mechanisms, and innovative techniques in crystallography. Beis’s findings have implications for drug discovery and combating antibiotic resistance, reflecting his commitment to bridging structural biology and applied microbiology.

• Cell biology
• Molecular biology
• Biochemistry
• +۷ مورد دیگر

Christian Baron is a Full Professor at the University of Montreal, holding dual affiliations in the Department of Biochemistry and Molecular Medicine and the Department of Microbiology, Infectiology and Immunology within the Faculty of Medicine. He currently serves as Vice-President (Programmes) at the Canadian Institutes of Health Research (CIHR) since February 2022. Previously, he was Vice-Dean of Research and Development at the Faculty of Medicine (2015–2020) and Department Head of Biochemistry and Molecular Medicine (2008–2015). His career began with a PhD in microbiology from Ludwig-Maximilians-Universität München (1993) followed by postdoctoral training at UC Berkeley. He has pioneered research in bacterial virulence mechanisms, focusing on type IV secretion systems (T4SS) and sulfur metabolism in extremophilic bacteria. His lab has developed inhibitors targeting T4SS components like Cagα to combat antibiotic-resistant pathogens. Key research themes include: Type IV secretion systems: Structural analysis of T-pilus assembly, inhibition of conjugation, and antivirulence drug discovery (e.g., VE607). Sulfur metabolism: Genomic approaches in Acidithiobacillus to understand bioremediation and mining waste management. His work is funded by major grants from NSERC, Genome Canada, and the Canadian Cancer Society. Notably, he has contributed to understanding the role of T4SS in horizontal gene transfer, enabling antibiotic resistance spread. Despite his administrative roles, he maintains an active research lab focused on structural biology, functional proteomics, and molecular mechanisms of bacterial virulence. Awards and Funding: Recipient of grants from CRSNG, Génome Canada, and CIHR committees. His leadership roles include serving on review panels for the Canadian Institutes of Health Research and NSERC. Advising and Labs: While his lab is currently closed to new students, his past trainees have contributed to seminal studies on T4SS assembly and sulfur oxidation pathways. Collaborative projects span structural biology (cryo-EM), bioinformatics, and high-throughput screening. Labs/Teams: Coordinates interdisciplinary teams at the University of Montreal, integrating biochemistry, molecular biology, and environmental microbiology to address global health challenges like antimicrobial resistance.