Konstantinos Beis

Konstantinos Beis is a Research Professor in Membrane Protein Structural Biology at Imperial College London's Department of Life Sciences, part of the Faculty of Natural Sciences. His research focuses on understanding bacterial pathogenesis and drug resistance mechanisms, particularly through the structural analysis of membrane proteins, ABC transporters, and antibacterial peptides. He holds affiliations with the Centre for Structural Biology, Research Complex at Harwell, and the Membrane Receptor Network.

His work employs advanced structural biology techniques such as cryo-EM, X-ray crystallography, and biophysical methods like PELDOR/EPR and smFRET. Key research themes include the structural basis of drug resistance, the mechanism of ABC transporters, and the development of novel antibacterial strategies. Beis collaborates with institutions like Diamond Light Source Ltd and has contributed to studies on Klebsiella pneumoniae, antimicrobial peptides, and conjugation systems in bacteria.

His publications span over two decades, with recent work emphasizing structural insights into transporters, antibiotic resistance mechanisms, and innovative techniques in crystallography. Beis’s findings have implications for drug discovery and combating antibiotic resistance, reflecting his commitment to bridging structural biology and applied microbiology.