Anne McCabe

Anne McCabe is an Assistant Professor at Albany College of Pharmacy and Health Sciences with a strong research focus on bacterial pathogenesis, particularly studying Klebsiella pneumoniae and its survival mechanisms during infection. She earned her BA in Molecular and Cellular Biology from Harvard University, PhD in Molecular Biology from Princeton University, and completed an IRACDA Postdoctoral Fellowship in the Department of Molecular Biology and Microbiology at Tufts University.

Dr. McCabe's research interests focus on understanding how opportunistic pathogens like Klebsiella pneumoniae survive diverse environmental stressors, including oxidative stress from the innate immune response and antibiotic treatment during infection. Her work spans bacterial stress response mechanisms, host-pathogen interactions, metal ion transport, and outer membrane biogenesis.

Analysis of her publication record from 2016-2024 reveals a strong focus on bacterial pathogenesis with particular emphasis on Klebsiella pneumoniae as a model organism. Her research combines molecular microbiology, structural biology, and infectious disease approaches to understand bacterial survival mechanisms during host infection. Key themes include antibiotic resistance mechanisms, bacterial metabolism during infection, and structural analysis of bacterial transport systems.

Her scientific contributions include important discoveries related to Klebsiella pneumoniae's ability to resist neutrophil killing, the role of amino acid biosynthesis in bacterial survival during lung infection, and structural insights into metal transport systems. Her 2024 publication on growth medium effects on drug interactions in Gram-negative bacteria represents her most recent contribution to the field.