معرفی
Jue Chen is the William E. Ford Professor at The Rockefeller University and an Investigator of the Howard Hughes Medical Institute. His research focuses on the structural and functional mechanisms of membrane transport proteins, particularly ATP-binding cassette (ABC) transporters and the cystic fibrosis transmembrane conductance regulator (CFTR). He employs structural biology techniques like X-ray crystallography and cryo-electron microscopy to study these proteins' roles in health and disease, including drug resistance, cancer, and cystic fibrosis.
Education:
- B.Sc. in Chemistry, Ohio University (1993)
- Ph.D. in Biochemistry, Harvard University (1998)
Research Interests:
- ABC transporter structure-function relationships
- Mechanisms of multidrug resistance in cancer
- CFTR dysfunction in cystic fibrosis
- Development of small-molecule therapeutics targeting membrane proteins
Awards:
- Pew Biomedical Scholar (2003)
- Anatrace Membrane Protein Award (2018)
Labs & Teams: Laboratory of Membrane Biology and Biophysics at Rockefeller University, collaborating with interdisciplinary teams in chemical biology and structural biology.
