
معرفی
Ina L. Urbatsch is a Professor at the Department of Cell Biology and Biochemistry, School of Medicine, Texas Tech University Health Sciences Center. Her research focuses on ABC transporters, particularly P-glycoprotein (Pgp) in cancer drug resistance, CFTR in cystic fibrosis, and ABCG5/ABCG8 in cholesterol transport disorders.
- Education: Ph.D. in Chemistry/Biochemistry from the University of Kaiserslautern, Germany
- Affiliation: Texas Tech University Health Sciences Center, Lubbock, TX
Research interests include structural and biochemical characterization of ABC transporters, their role in diseases, and the development of inhibitors for therapeutic applications. Key projects involve understanding ATP hydrolysis mechanisms, conformational changes, and lipid/protein interactions.
Recent publications highlight studies on drug-stimulated ATPase activity in Pgp, CFTR stabilization, structural insights into ABCG5/ABCG8, and functional analysis of sodium-coupled transporters. Articles span 2021–2024, utilizing techniques like cryo-EM, X-ray crystallography, and directed evolution.
Selected collaborations include researchers at NCBI, Google Scholar, and institutions studying multidrug resistance, cystic fibrosis, and lipid metabolism. No explicit awards or student advisement details are listed, but her work emphasizes biophysical methods and protein purification strategies.
Ina L. Urbatsch در جاهای دیگر
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