جستجوی استاد راهنمای دانشگاهی

Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

• Systems Biology
• Signal Transduction
• Cell Communication
• +۵ مورد دیگر

Hang Lu is an Associate Professor in the Department of Communication and Media at the University of Michigan's College of Literature, Science, and the Arts. He specializes in science, health, environmental, and risk communication (ComSHER), with a focus on media psychology. His research explores audience responses to media messages about sensitive topics and strategies to enhance message effectiveness. Lu holds a Ph.D. in Communication from Cornell University (2018), along with advanced degrees from Cornell, Marquette University, and Central South University in China. He directs the Media and Risk (MaR) Lab and previously served as a postdoctoral fellow at the Annenberg Public Policy Center. His research spans four main areas: 1) emotion dynamics in media responses, 2) predictors of information behaviors, 3) media effects on stigmatization, and 4) AI applications in sensitive domains. He has published in journals like Journal of Communication , Risk Analysis , and Public Understanding of Science , earning multiple top paper awards. As Vice Chair of the Environmental Communication Division at the International Communication Association, Lu contributes to interdisciplinary dialogue. His work addresses critical societal issues such as climate change communication, vaccination hesitancy, and emerging technology ethics.

• Science Communication
• Health Communication
• Environmental Communication
• +۴ مورد دیگر

Michael Harrison is an Assistant Professor in the Department of Cell and Developmental Biology at Weill Cornell Medicine, where he leads the Regeneration and Development Lab within the Graduate School of Medical Sciences. His research focuses on vascular development and regeneration using zebrafish as a model organism, with emphasis on coronary and cerebral vasculature. Education: B.Sc. in Genetics, University of Edinburgh (2005) Ph.D. in Developmental Genetics, University of Sheffield (mentor: Vincent Cunliffe) Postdoctoral Fellowship, Saban Research Institute, Children’s Hospital Los Angeles (CIRM Fellow) Harrison's research centers on understanding how blood and lymphatic vessels form and regenerate, particularly in the heart and brain. His lab investigates coronary vessel development, the role of lymphatic systems in inflammation and regeneration, and revascularization after injury. By leveraging zebrafish genetics and advanced imaging, his work aims to uncover pathways that could be harnessed for regenerative therapies in humans. His recent publications reveal key signaling mechanisms such as Cxcr4-Cxcl12 in coronary development and the two-step formation of cardiac lymphatics. The 15 most recent articles demonstrate a strong, consistent research trajectory in vascular biology and regeneration, with increasing use of advanced techniques like single-nuclei multiomics, fluidic imaging devices, and CRISPR-based genome editing. His work spans developmental mechanisms, functional imaging, and translational applications in cardiac repair. Scientific Awards: No awards explicitly mentioned in the provided text. Harrison actively mentors a team of postdoctoral fellows, research assistants, and students, several of whom have progressed to medical school or research careers. His lab collaborates extensively, particularly with Ching-Ling Lien's group. He has secured research space and funding to support ongoing projects in cardiac and cerebral vasculature. The lab is actively recruiting rotation students from BCMB, PBSB, IMP, and Tri-Institutional programs, as well as postdoctoral researchers and research assistants, indicating an expanding research team and active grant support. Labs and Teams: Regeneration and Development Lab, Weill Cornell Medicine Collaborations with Ching-Ling Lien Lab Member of Tri-Institutional PhD Programs Active participation in BCMB, PBSB, and IMP training programs

• Vascular Biology
• Regenerative Medicine
• Developmental Biology
• +۱۱ مورد دیگر

Dr. Brandon K. Hadland is an Associate Professor at the University of Washington School of Medicine in Pediatrics and Fred Hutchinson Cancer Center's Translational Science and Therapeutics Division, with memberships in the Immunotherapy and Translational Data Science Integrated Research Centers. He serves as an Attending Physician at Seattle Children's Hospital for Pediatric Hematology/Oncology and Bone Marrow Transplant. Education: BS in Chemistry, Harvey Mudd College (1998) MD and PhD in Molecular Cell Biology, Washington University School of Medicine (2006) Pediatrics Residency and Internship, Seattle Children's/University of Washington (2006-2009) Pediatric Hematology/Oncology Fellowship, Seattle Children's/University of Washington/Fred Hutch (2009-2012) His research centers on embryonic hematopoietic stem cell (HSC) development, investigating Notch signaling pathways, vascular microenvironments in the AGM region and fetal liver, and engineering in vitro platforms to model blood formation. He employs single-cell functional and molecular techniques to characterize niche interactions and transcriptional programs driving HSC emergence. Recent publications demonstrate trends in applying single-cell transcriptomics to define HSC-competent hemogenic endothelium and develop stromal-free engineered niches, bridging developmental biology with therapeutic applications for blood disorders and leukemia. Dr. Hadland leads collaborative research across Fred Hutch and UW, partnering with experts in computational genomics (Dr. Cole Trapnell), stem cell engineering (Drs. Sergei Doulatov and Ying Zheng), and pediatric oncology (Drs. Soheil Meshinchi and Irv Bernstein) to advance cellular therapies and leukemia prevention strategies.

• Hematopoietic stem cell development
• Notch signaling
• Hematopoietic niche
• +۵ مورد دیگر

Megan Laura McCain is a Professor of Biomedical Engineering at the University of Southern California (USC), with a secondary appointment in the Department of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine. She leads the McCain Lab, focused on developing microphysiological systems, particularly heart- and muscle-on-a-chip models, to study disease mechanisms and therapeutic responses. McCain holds affiliations with the Biomedical Engineering Society, American Society for Cell Biology, and American Heart Association. Her education includes a B.S. in Biomedical Engineering from Washington University in St. Louis (2006), a Ph.D. in Engineering and Applied Sciences from Harvard University (2012), and postdoctoral research at Harvard’s Wyss Institute. Notable awards include the American Heart Association Pre-doctoral Fellowship and Harvard’s Derek Bok Certificate of Distinction in Teaching. McCain’s research integrates tissue engineering, stem cell biology, and microfluidics to model complex biological systems. Her work emphasizes understanding how microenvironments influence cellular behavior in diseases like cardiovascular disorders and muscular dystrophy. Recent studies explore paracrine interactions in engineered tissues, sex-based proteomic differences in vascular cells, and hypoxia-induced signaling in cardiac fibroblasts. Her scientific contributions include advancements in 3D bioprinting, microfluidic platforms for disease modeling, and synthetic biology tools for cellular control. McCain’s lab collaborates widely to translate findings into clinical applications, such as personalized medicine and regenerative therapies.

• Biomedical Engineering
• Tissue Engineering
• Regenerative Medicine
• +۴ مورد دیگر

Andrea H. Brand serves as the Frederick L. Ehrman Professor of Cell Biology and Professor of Neuroscience at NYU Grossman School of Medicine, New York University, where she chairs the Department of Cell Biology. Her dual appointments reflect an interdisciplinary research program spanning molecular mechanisms of stem cell regulation and neural development. Dr. Brand earned her PhD from the University of Cambridge followed by prestigious postdoctoral fellowships: a Leukemia Society Special Fellowship at Harvard Medical School and a Helen Hay Whitney Fellowship at Harvard University. These foundational experiences established her expertise in genetic model systems. Her research integrates stem cell biology and neuroscience through innovative work with Drosophila and mouse models. Key investigations focus on chromatin dynamics in stem cell quiescence, Notch/insulin signaling pathways, neural progenitor reprogramming, and blood-brain barrier formation. Current projects explore obesity-related gene function and CHD8 genomic targets relevant to neurodevelopmental disorders, emphasizing translational potential for regenerative medicine. Recent publications (2020-2022) reveal consistent themes in stem cell niche organization and disease mechanisms, with notable contributions to understanding tumorigenesis through neural progenitor studies and metabolic influences on barrier development. Her work demonstrates strong interdisciplinary convergence between developmental genetics and systems neuroscience. No scientific awards were documented in the provided profile information. While the profile indicates Professor Brand's leadership as Department Chair, specific details regarding student mentorship, grant funding, or laboratory structure were not included in the available text. Her position suggests active supervision of research teams and potential involvement in major collaborative initiatives.

• Stem Cell Biology
• Neuroscience
• Developmental Biology
• +۳ مورد دیگر

Wendy R Gordon serves as an Associate Professor in the Structural Biology and Biophysics department at the University of Minnesota Medical School. Her research program bridges structural biology, biophysics, and translational medicine with significant funding from NIH sources including the National Cancer Institute and National Institute of General Medical Sciences. Dr. Gordon leads multiple active research projects focused on mechanobiology, protein engineering, and cancer therapeutics. Dr. Gordon's research interests center on understanding molecular mechanisms of cell surface receptors, particularly the Notch signaling pathway, and developing innovative tools for studying cellular mechanics. Her work spans structural biology approaches to characterize protein-DNA interactions, mechanotransduction mechanisms, and receptor regulation. She has developed novel technologies including HUH-Tags for protein-DNA labeling and tension sensors for measuring cellular forces. Her research has significant implications for cancer immunotherapy, particularly in engineering protein modulators of Notch activation for CAR T-cell therapy. Analysis of Dr. Gordon's recent publications reveals a strong focus on three interconnected research themes: 1) molecular mechanisms of Notch signaling and receptor regulation, 2) development of innovative tools for protein-DNA conjugation and cellular mechanotype measurement, and 3) applications of these technologies to cancer biology and immunotherapy. Her work demonstrates increasing integration of structural biology with functional cellular assays and therapeutic applications, particularly in tumor microenvironment and immunotherapy contexts. Dr. Gordon currently leads or collaborates on seven major research projects totaling millions in NIH funding. Her active grants include: LUMICKS C-trap for Mechanistic Studies of Biological Systems (as PI), Engineering Protein Modulators of Notch Activation for CAR T-cell immunotherapy (as CoI), Viral vector technology for cell type specific gene delivery (as CoI), Decoding mechanotransduction mechanisms of cell-surface receptors (as PI), and the Center for Multiparametric Imaging of Tumor Immune Microenvironments (as CoI). These projects reflect her expertise spanning structural biology, mechanobiology, and translational applications. Dr. Gordon's laboratory operates at the intersection of structural biology and cellular mechanobiology, with strong collaborations across the University of Minnesota campus including with cancer researchers, bioengineers, and clinicians. Her team develops and applies cutting-edge technologies including single-molecule techniques, protein engineering approaches, and high-throughput cellular mechanotype measurement systems to address fundamental questions in receptor biology with therapeutic implications.

• Structural Biology
• Biophysics
• Notch Signaling
• +۷ مورد دیگر

Heather R. Christofk is a Professor in the Department of Biological Chemistry at the David Geffen School of Medicine at UCLA. Her research focuses on the intricate relationship between cellular metabolism and various biological processes, particularly in the contexts of cancer development, stem cell function, and viral infections. Education: PhD in Cell and Developmental Biology from Harvard University (2007) BS in Molecular, Cell, and Developmental Biology from UCLA (2001) Dr. Christofk's research program centers on understanding how metabolic pathways regulate cellular processes in both normal physiology and disease states. Her laboratory has made significant contributions to understanding how cancer cells reprogram their metabolism to support rapid growth and proliferation, with particular focus on glucose metabolism, amino acid utilization, and metabolic adaptations in tumor microenvironments. She has also pioneered work on the metabolic regulation of stem cell function, especially in hair follicle stem cells, demonstrating how metabolic pathways control stem cell activation and differentiation. Her research has important implications for developing novel therapeutic approaches that target cancer metabolism while preserving normal tissue function. Analysis of Dr. Christofk's recent publications reveals a strong focus on metabolic heterogeneity across different biological contexts. Her work spans cancer metabolism (particularly in liposarcoma, melanoma, and hepatocellular carcinoma), stem cell metabolism (especially hair follicle stem cells), viral metabolism (including Epstein-Barr virus and Zika virus), and developmental metabolism (fetal development and organogenesis). A recurring theme is how metabolic pathways serve as regulatory nodes that control cell fate decisions, tumor progression, and therapeutic responses. Selected Research Funding: Metabolic Control of Hair Follicle Stem Cell Homeostasis and Tumorigenesis (NIH R01AR070245, 2018-2023) - Co-Principal Investigator Nutrient regulation of cancer cell growth (NIH R01CA215185, 2017-2022) - Principal Investigator Regulation of the Warburg Effect in Cancer (NIH DP2OD008454, 2011-2016) - Principal Investigator Dr. Christofk's laboratory maintains active collaborations across multiple disciplines, working with clinicians, basic scientists, and computational biologists to address complex questions in metabolism and disease. Her team employs a range of cutting-edge techniques including metabolomics, stable isotope tracing, molecular biology, and in vivo models to investigate metabolic regulation in health and disease.

• Cancer Metabolism
• Stem Cell Metabolism
• Metabolic Regulation of Cell Growth
• +۵ مورد دیگر

Dr. Yuuki Obata is an Assistant Professor in the Department of Immunology and Neuroscience at UT Southwestern Medical Center, USA. He holds an Investigator role at the O'Donnell Brain Institute. Previously, he served as a postdoctoral fellow at the Francis Crick Institute (2016-2021) and the University of Tokyo (2015-2016). His research focuses on how environmental signals (microbiota, diet, circadian rhythms) shape intestinal neural circuits and immune networks. He employs advanced techniques including imaging, viral tracing, gnotobiotic systems, and multi-omics approaches. Education: PhD in Immunology from Chiba University (RIKEN Joint Graduate School Program), Japan. Postdoctoral training included JSPS Superlative Postdoctoral Fellowships (Japan) and EMBO/HFSP fellowships (UK). Research interests span microbiota-immune interactions, enteric nervous system development, gut-brain axis communication, and epigenetic regulation of immune responses. His lab investigates mechanisms linking microbial metabolites to host physiology, particularly in metabolic and neural contexts. Key findings include microbiota's role in IgA responses, T cell differentiation, and neuronal programming. Collaborations emphasize inter-organ communication and translational applications in immunology and neuroscience. Laboratory: The Obata Lab at UT Southwestern employs interdisciplinary methods to address how environmental factors reprogram gut neural and immune systems. Future work includes exploring microbiota-based therapies and neuroimmune interactions in disease models.

• Gut Microbiota Research
• Immune System Regulation
• Enteric Nervous System Development
• +۳ مورد دیگر

Ramana V Davuluri serves as Professor in the Department of Biomedical Informatics at Stony Brook University's Renaissance School of Medicine. With over 20 years of experience in bioinformatics and computational genomics, he leads research at the intersection of machine learning and cancer genomics, focusing on translating high-dimensional -omic data into clinically actionable insights through statistically rigorous methodologies. Dr. Davuluri's research spans Machine Learning applications in Cancer Data Science , isoform-level gene regulation , and precision-medicine development. His lab pioneers bioinformatics solutions for genomic data interpretation, with emphasis on developing machine learning algorithms that convert NextGen sequencing outputs into experimentally testable discovery models. A core focus involves creating rapid biomarker identification systems from human tissue and blood samples through integrated computational-experimental approaches in systems biology. Analysis of his 2023-2025 publications reveals a dominant trend toward genomic foundation models (e.g., DNABERT variants), multi-omic cancer subtyping , and time-dependent therapeutic strategies for pediatric brain tumors and ovarian cancer. His work consistently bridges computational innovation with biological validation across diverse cancer types including glioma, lung adenocarcinoma, and high-grade serous carcinoma. As Principal Investigator for multiple multi-investigator and multi-site projects, Dr. Davuluri directs research integrating high-throughput experimental procedures with advanced data-mining techniques. His laboratory maintains strong collaborations across oncology, neuroscience, and immunology domains while developing genomics-based decision support systems for clinical translation. The Davuluri Lab employs a systems biology framework to develop novel informatics tools for precision oncology, with particular emphasis on translating genomic discoveries into clinical applications through biomarker discovery and therapeutic strategy optimization.

• Machine Learning
• Cancer Data Science
• Gene Regulation
• +۴ مورد دیگر

Wanfen Xiong, MD, PhD, is an Associate Professor specializing in General Surgery, with a focus on cardiovascular and vascular pathologies. Their research primarily investigates aortic aneurysms, Marfan syndrome, and inflammatory mechanisms in vascular diseases using mouse models and humanized systems. Xiong serves as Principal Investigator (PI) for two major projects exploring the role of smooth muscle cell phenotypic switches in aortic pathology associated with Marfan syndrome. With a strong publication record spanning over two decades, they have contributed significantly to understanding molecular pathways like Notch3 signaling and CD95L-mediated inflammation in cardiovascular disorders. Their work integrates immunology and molecular biology to develop therapeutic strategies for complex vascular conditions. Research interests include vascular biology, genetic disorders affecting the aorta, and translational approaches to inhibit aneurysm progression. Xiong's studies frequently utilize mouse models to simulate human pathologies, with recent emphasis on regulatory T cells and neuroinflammation in heart failure contexts. Their findings have been cited over 3,389 times, reflecting impactful contributions to cardiovascular research.

• Vascular Surgery
• Cardiovascular Disease
• Aortic Aneurysm Research
• +۳ مورد دیگر

David Weisblat is a Professor in the Department of Molecular and Cell Biology at UC Berkeley's College of Letters & Science. His research focuses on developmental and evolutionary processes in glossiphoniid leeches (e.g., Helobdella ), particularly their segmentation mechanisms and molecular phylogeny within Lophotrochozoa. He leads studies integrating embryological, genomic, and genetic approaches to understand how developmental pathways evolved across bilaterian animals. Research Interests: Weisblat’s work addresses how cell fates and signaling pathways (WNT, NOTCH, TGFβ) shape leech development, with emphasis on the evolutionary origins of segmentation. His lab combines microinjection techniques, transcriptome analysis, and CRISPR mutagenesis to explore stem cell dynamics and conserved developmental programs. Key Projects: Current efforts investigate grandparental stem cell divisions in segmentation and intercellular signaling during early embryogenesis. The lab’s genomic resources—including BAC libraries and EST databases—facilitate comparative studies across Lophotrochozoan taxa. Lab Contributions: The Weisblat lab pioneered Helobdella as a model organism, enabling breakthroughs in Evo-Devo. Their findings bridge developmental plasticity and evolutionary innovation, particularly in annelids versus arthropods/deuterostomes.

• Developmental Biology
• Evolutionary Developmental Biology (Evo-Devo)
• Molecular Phylogenetics
• +۴ مورد دیگر

Albert Erives is an Associate Professor in the Department of Biology at the University of Iowa , specializing in regulatory genomics, evolutionary genomics, and the evolution of metazoans. His research focuses on decoding gene regulatory logic in DNA sequences, particularly during animal embryogenesis, using comparative genomics to identify regulatory modules driving phylogenetic transitions. PhD from University of California, Berkeley His work spans eukaryotic gene regulation, integrating biochemistry, molecular genetics, and computational biology to uncover principles of organismal evolution. Recent studies include viral nucleosome structure, Notch signaling pathway evolution, and enhancer organization in model organisms like Drosophila and Ciona . Notable scientific awards include the NSF CAREER Award (2012, 2010) . He actively seeks graduate students and postdoctoral researchers for his laboratory, which utilizes core facilities such as the Carver Center for Genomics.

• Regulatory Genomics
• Evolutionary Genomics
• Evolution of Metazoa
• +۶ مورد دیگر

Dr. Marcias Martinez is a Professor & Chair of the Mechanical & Aerospace Engineering Department at Clarkson University, affiliated with the Coulter School of Engineering & Applied Sciences and the Center for Advanced Materials Processing (CAMP). He holds a Ph.D. (2006) and M.S. (1999) in Mechanical Engineering from Carleton University, along with a B.S. (1995) in the same field. Roles: Chair of Mechanical & Aerospace Engineering, Principal Investigator of the HolSIP Lab. Affiliations: Clarkson University, CAMP, and collaborations with TU Delft and industry partners. His research focuses on the development of the Holistic Structural Integrity Process (HolSIP) , integrating advanced technologies like Structural Health Monitoring (SHM), Machine Learning, and Finite Element Analysis to assess aerospace and mechanical structure reliability. Key areas include: Composite materials and fatigue analysis Load monitoring and fracture mechanics Adaptive structures and sensor fusion Publications emphasize experimental and computational methods, with recent trends in: Material characterization (viscoelastic behavior, composites) NDT techniques (ultrasonic, fiber optics) Structural durability and failure prediction Recipient of prestigious awards like the AIAA Associate Fellow (2023) and Charles H. Jennings Award (2020) . Active in mentoring over 20 graduate students and securing grants from the NSF, ONR, and industry. Labs include advanced equipment: Luna fiber optic systems, electromechanical test frames, and computational clusters. Collaborations span academia (TU Delft) and industry (Lockheed Martin, Dassault Foundation).

• Structural Integrity Analysis
• Structural Health Monitoring (SHM)
• Composite Materials
• +۵ مورد دیگر

Caglar Oskay is the Cornelius Vanderbilt Professor of Engineering and Chair of the Department of Civil and Environmental Engineering at Vanderbilt University. He is also a Professor of Mechanical Engineering. His research focuses on multiscale computational modeling of material and structural systems under extreme conditions, with expertise in composite materials, failure mechanisms, and computational mechanics. Dr. Oskay earned his Ph.D. in Civil Engineering from Rensselaer Polytechnic Institute (2003) and has held academic roles there before joining Vanderbilt in 2006. He was honored as an ASME Fellow in 2017 and as a Chancellor Faculty Fellow in 2016. Key research areas include multiscale failure modeling, life prediction of heterogeneous materials, and computational methods for composites and multiphysics systems. His work integrates advanced simulation techniques with experimental validation, addressing challenges in infrastructure resilience, additive manufacturing defects, and quantum computing applications in engineering. Education: Ph.D., Civil Engineering, Rensselaer Polytechnic Institute (2003) M.S., Civil Engineering, Rensselaer Polytechnic Institute M.S., Applied Mathematics, Rensselaer Polytechnic Institute B.S., Civil Engineering, Middle East Technical University Recent research highlights include stochastic modeling of geotechnical infrastructure failures, quantum-enhanced finite element methods, and predictive analytics for additive manufacturing defects. He leads interdisciplinary efforts on backward erosion piping in flood protection systems and has secured grants for multiscale modeling of titanium alloys and composites. Awards: ASME Fellow (2017) Chancellor Faculty Fellow (2016) Advising and grants: Dr. Oskay’s grants include NSF-funded studies on backward erosion piping and quantum computing applications. His research group collaborates with industry partners on materials for aerospace and energy sectors, emphasizing computational tools for failure prediction and material design. His work bridges computational mechanics with practical engineering challenges, advancing methods for infrastructure resilience, advanced materials, and sustainable design through multiscale modeling innovations.

• Multiscale Computational Modeling
• Composite Materials
• Structural Failure Analysis
• +۷ مورد دیگر