معرفی
Wanfen Xiong, MD, PhD, is an Associate Professor specializing in General Surgery, with a focus on cardiovascular and vascular pathologies. Their research primarily investigates aortic aneurysms, Marfan syndrome, and inflammatory mechanisms in vascular diseases using mouse models and humanized systems. Xiong serves as Principal Investigator (PI) for two major projects exploring the role of smooth muscle cell phenotypic switches in aortic pathology associated with Marfan syndrome. With a strong publication record spanning over two decades, they have contributed significantly to understanding molecular pathways like Notch3 signaling and CD95L-mediated inflammation in cardiovascular disorders. Their work integrates immunology and molecular biology to develop therapeutic strategies for complex vascular conditions.
Research interests include vascular biology, genetic disorders affecting the aorta, and translational approaches to inhibit aneurysm progression. Xiong's studies frequently utilize mouse models to simulate human pathologies, with recent emphasis on regulatory T cells and neuroinflammation in heart failure contexts. Their findings have been cited over 3,389 times, reflecting impactful contributions to cardiovascular research.
