معرفی
Ming Cui Gong is a Professor at the University of Kentucky with appointments in the Department of Physiology, Saha Cardiovascular Research Center, and Saha Aortic Center. His research bridges vascular physiology and metabolic disease through innovative mouse model systems.
Education:
- Ph.D., Peking Union Medical College, China and University of Virginia, 1994
Dr. Gong's work centers on two critical vascular pathologies: (1) blood pressure circadian rhythm disruption in diabetes (affecting 75% of patients with worsened outcomes), where his lab discovered protective roles for GLP-1R agonists and time-restricted feeding; and (2) sex-dimorphic aortic aneurysm mechanisms using their novel aldosterone/salt-induced mouse model. His research integrates physiological, molecular, and genetic approaches to investigate intrinsic clock dysregulation, vascular contractility, and sex-specific pathways involving PD-1, estrogen, and IL-6.
Publication analysis (2015-2021) reveals an evolving focus from foundational circadian gene studies (BMAL1 in smooth muscle) to translational diabetes interventions and sex-difference mechanisms in aneurysms. Key trends include the emergence of time-restricted feeding as a therapeutic strategy and the elucidation of molecular sex dimorphisms in vascular disease.
As a core member of the Saha Cardiovascular Research Center, Dr. Gong collaborates on interdisciplinary aortic disease research. Details regarding student advising and grant funding were not specified in source materials.
