جست‌وجوی استاد و پژوهشگر

Shoib Siddiquiمشاهده پروفایل

مدرس ارشد

• Cancer Biology
• Immunology
• Glycobiology
• +۴ مورد دیگر

Dr. Shoib Siddiqui is a Senior Lecturer at the University of Hertfordshire's School of Life and Medical Sciences, specializing in cancer biology, immunology, and glycobiology. Previously, he held positions at the American University of Ras Al Khaimah and conducted postdoctoral research at UC San Diego under Prof. Ajit Varki. His research focuses on sialic acids, Siglecs, and microRNA mechanisms in cancer, Alzheimer’s, and sepsis. He earned his Ph.D. from ETH Zurich, investigating neuropilin-2 in skin cancer progression. Education: Ph.D. in Vascular Biology, Immunology, and Cancer Biology (ETH Zurich, 2009–2013) M.Sc. in Biotechnology (IIT Bombay, 2008) Research Focus: Dr. Siddiqui’s work explores cancer progression pathways, tumor biomarkers, and novel therapies. Key areas include Siglec-sialoglycan interactions, microRNA targeting, and drug repurposing for colorectal cancer. His recent projects involve developing RNAi therapeutics and inhibitors for Siglec-15. Projects: Fluralaner as a Colorectal Cancer Therapeutic (2026–2027) ADAMTS-7 Inhibition for Coronary Artery Disease (2022) UK-China Mycotoxin Reduction Alliance (2022–2023) Publications: Over 39 peer-reviewed articles in journals like Journal of Clinical Investigation , PNAS , and Blood , with a focus on oncology, glycobiology, and immunology. Recent trends emphasize Siglec-targeted therapies, microRNA networks, and drug repurposing strategies. Awards: No formal awards listed, but noted for impactful publications in high-impact journals. Advising & Grants: Served as Principal Investigator (PI) on RNAi therapeutics and Co-Investigator (CoI) on Siglec-15 and ADAMTS-7 projects. Collaborations span international institutions and cross-disciplinary teams. Labs/Teams: Active in the Biosciences Research Group and Centre for Research in Mechanisms of Disease and Drug Discovery at UH. Collaborates with global researchers in glycobiology and oncology.

Kathy Iovineمشاهده پروفایل

استاد

• Developmental Biology
• Regeneration
• Skeletal Morphogenesis
• +۴ مورد دیگر

Kathy Iovine serves as Professor and Department Chair at Lehigh University, leading research in skeletal development and regeneration using zebrafish models. Her work focuses on elucidating molecular mechanisms controlling bone growth through fin regeneration studies. Her primary research interests span developmental biology, regeneration, skeletal morphogenesis, cell-cell communication, and extracellular matrix dynamics. She investigates how connexin43 (Cx43)-mediated gap junctional communication coordinates skeletal growth and patterning, with emphasis on segment addition in zebrafish fins as the fundamental unit of bone growth. Key areas include semaphorin signaling, hyaluronic acid metabolism, and collagen-based actinotrichia structures. Analysis of her publication record reveals consistent exploration of Cx43-dependent networks across 15+ recent studies. Her work demonstrates how mutations in connexin43 disrupt fin length regulation through effects on cell proliferation and joint formation, identifying critical mediators like Sema3d and Hapln1a. The research integrates genetic, molecular, and cellular approaches to dissect pathways governing skeletal morphogenesis. Dr. Iovine directs an active research laboratory investigating the genetic basis of skeletal development. Her team has characterized how actinotrichia integrity signals between proliferating and differentiating cell compartments to coordinate growth, and how Cx43 regulates extracellular environment modifiers. Current efforts focus on validating additional genes within the Cx43-dependent network to uncover novel therapeutic targets for skeletal disorders.

Caroline Pellet-Manyمشاهده پروفایل

مدرس ارشد

• Cardiovascular Biology
• Cardiac Regeneration
• Atherosclerosis
• +۴ مورد دیگر

Dr. Caroline Pellet-Many serves as a Senior Lecturer in Biomedical Sciences at the Royal Veterinary College (RVC), specializing in Cardiovascular Biology within the Department of Comparative Biomedical Sciences at the Camden campus. She is an active member of the Cardiovascular and Renal Biology research group and CPCS Research Programme, teaching across BVetMed and BSc Biological Sciences degrees while co-directing BSc/MSci programmes. Academic Background: Undergraduate & Maitrise in Biology, Université Louis Pasteur, Strasbourg MSc in Physiology (Distinctions), Birkbeck College PhD in Cardiovascular Biology, University College London (2010) Her research centers on gene regulation and molecular mechanisms in cardiovascular diseases , utilizing in vivo models to investigate smooth muscle cells and macrophages in atherosclerotic plaque formation. She pioneers zebrafish models for cardiac regeneration studies, examining epicardial/endocardial roles and fin regeneration for angiogenesis. Current work focuses on Neuropilins (NRP1/NRP2) in macrophage polarization during heart repair, with implications for therapeutic interventions. Analysis of her 15 most recent publications reveals consistent focus on neuropilin signaling in cardiovascular contexts, particularly cardiac regeneration mechanisms using zebrafish models, atherosclerosis progression, and angiogenesis regulation. Key themes include receptor crosstalk (VEGFR2, PDGFR), cellular migration pathways, and inflammatory modulation in vascular disease. Professional Recognition: Fellow of the Higher Education Academy Dr. Pellet-Many supervises BSc, MSci, and PhD students including Petra Mendes-Vieira's project on neuropilins in zebrafish heart regeneration. She serves on the London Vascular Biology Forum committee and the British Small Animal Veterinary Association grant award committee, while actively promoting cardiovascular health through British Heart Foundation outreach and RVC's 'Night at the Vet College' events. As a core member of RVC's Cardiovascular and Renal Biology group, she integrates zebrafish regeneration models with molecular techniques to investigate therapeutic targets for heart disease, emphasizing translational applications in veterinary and human medicine.

• Neuroscience
• Neurosurgery
• Traumatic Brain Injury
• +۴ مورد دیگر

Mattias Sköld serves as an Adjunct Lecturer at Karolinska Institutet's Department of Neuroscience and Associate Professor of Neurosurgery at Uppsala University, concurrently functioning as Senior Consultant Neurosurgeon at Akademiska Sjukhuset Uppsala and Senior Researcher in Neuroscience. His academic credentials include: M.D. from Karolinska Institutet (2003) Ph.D. in Neuroscience from Karolinska Institutet (2004) Medical Internship at Karolinska University Hospital (2004-2006) Neurosurgery residency at Akademiska Sjukhuset Uppsala (2006, 2012-2019) Sköld's research investigates traumatic nervous system injuries through methodologies ranging from in vitro cavitation models to animal studies, with military medicine applications forming a critical focus. His work examines blast-induced trauma mechanisms, neural regeneration pathways, and molecular responses to high-energy injuries, particularly emphasizing VEGF signaling and inflammatory cascades in neural repair processes. Analysis of his 15 most recent publications reveals consistent exploration of blast injury modeling frameworks, peripheral nerve regeneration techniques using biomaterials, and temporal gene expression patterns following neural trauma across military and civilian contexts. No scientific awards are documented in the provided materials. He supervises Ph.D. students in both basic neuroscience and clinical neurosurgery domains. Current research is supported by Swedish Research Council grants including "Novel strategies for nervous tissue regeneration" (2020-2023) and previously "Targeted anti-inflammatory treatment in traumatic brain injuries" (2009-2010). Sköld leads Karolinska Institutet's Experimental Traumatology Research Unit and contributes to multiple NATO human factors and medicine task groups focused on brain injury modeling standards and combat casualty care performance metrics.

Jeffrey Martinمشاهده پروفایل

استاد

• Kaposi's Sarcoma
• HIV-Associated Malignancies
• Clinical Research
• +۷ مورد دیگر

Jeffrey Martin is a Professor at the University of California San Francisco (UCSF) with over two decades of expertise in clinical research, epidemiology, and HIV-associated malignancies. He leads the UCSF Training in Clinical Research (TICR) Program and co-directs the Population and Clinical Sciences Core of the NIH-sponsored UCSF CFAR. His work spans observational and experimental studies in the U.S. and Africa, focusing on Kaposi’s sarcoma (KS), SARS-CoV-2, and immune dysregulation. He has directed large-scale cohorts like the UCSF SCOPE cohort and the Uganda AIDS Rural Treatment Outcomes (UARTO) Cohort , contributing to over 250 publications. Education includes a BA in Biology from Johns Hopkins University, an MD from the University of Pennsylvania, an MPH in Epidemiology from UC Berkeley, and fellowships in Infectious Diseases and AIDS Prevention at UCSF. His research in HIV-associated cancers, Long COVID, and viral immunology integrates study design, biostatistical analysis, and implementation science. Recent work explores SARS-CoV-2 antigen persistence, T cell dysfunction, and post-acute sequelae. He has pioneered diagnostic tools like KS-Detect for low-resource settings. Scientific Awards include the Phi Beta Kappa Alpha Omega Alpha Merck Manual Award New Investigator Award (UCSF CFAR) Stephen B. Hulley Award As PI or Co-PI on NIH grants such as U54CA254571 (USEAHAMRC) and R01CA119903 , he advances global health initiatives, mentoring junior researchers and managing multicenter collaborations like the East Africa IeDEA Consortium .

Mark B. Meyerمشاهده پروفایل

استادیار

• Vitamin D metabolism
• Chromatin environment
• Serum calcium and phosphate maintenance
• +۸ مورد دیگر

Mark B. Meyer is an Assistant Professor in the Department of Nutritional Sciences at the University of Wisconsin-Madison. He is also a member of the UW Carbone Cancer Center in the Cancer Genetics & Epigenetic Mechanisms program. Dr. Meyer mentors students across multiple programs including Endocrinology and Reproductive Physiology (ERP), Molecular and Environmental Toxicology (MET), Genetics (GEN), Cellular and Molecular Biology (CMB), Metabolism and Nutrition Training Program (MANTP), and the Biotechnology Training Program (BTP). Dr. Meyer received his B.S. in Chemistry from Butler University in 2002 and his Ph.D. in Biochemistry from the University of Wisconsin-Madison in 2007, followed by a postdoctoral position at the same institution. Dr. Meyer's research focuses on the dynamic chromatin environment responsible for serum calcium and phosphate maintenance and the impacts of vitamin D metabolism in skeletal, renal, and intestinal biology. His work examines how endocrine hormones like parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol maintain mineral balance through genomic changes. His lab investigates how dysfunction in these mechanisms contributes to chronic kidney disease-metabolic bone disorder (CKD-MBD), atherosclerosis, inflammatory bowel disease (IBD), and cancer. Dr. Meyer's research particularly explores the epigenetic programming effects of vitamin D deficiency, including how maternal vitamin D deficiency in mice imprints epigenetic changes leading to insulin resistance and diabetes in offspring. His laboratory employs unique animal models, genomic editing techniques, and -omics bioinformatic approaches to generate unbiased interrogation of chromatin changes. Recent publications highlight work on vitamin D receptor actions, renal vitamin D metabolism, and the genomic consequences of mineralotropic hormone signaling, revealing intricate regulatory networks involving CREB modules, salt-inducible kinases, and vitamin D response elements that coordinate renal Cyp27b1 and Cyp24a1 expression. Dr. Meyer has received recognition for his contributions to vitamin D research, as evidenced by his numerous publications in high-impact journals and participation in major scientific workshops including the 24th workshop on vitamin D in Austin. His research program is supported by multiple NIH-funded training programs, reflecting the interdisciplinary nature of his work at the intersection of nutrition, genomics, and metabolic disease, with particular emphasis on understanding how dietary and nutritional supplementation of vitamin D affects inflammatory disease progression and cancer outcomes.

Tommaso Angeloneمشاهده پروفایل

استاد

• Cardiovascular Physiology
• Molecular and Cellular Pathophysiology
• Cardioprotection
• +۷ مورد دیگر

Tommaso Angelone is a Full Professor of Physiology at the University of Calabria (UNICAL), affiliated with the Department of Biology, Ecology and Earth Sciences. He serves as Scientific Director of the Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology and leads a dynamic research team. His academic roles include Coordinator of the Doctorate Fellowship in Life Sciences and Technology and President of the Italian Society of Cardiovascular Research (SIRC) since 2020. Dr. Angelone's research focuses on the neurohumoral regulation of cardiac function, particularly cardioprotection in ischemia/reperfusion injury and heart failure. His work investigates the roles of chromogranin-A derived peptides, selenoprotein T, nitric oxide, and nutrition-related hormones such as nesfatin-1 and phoenixin. Utilizing advanced techniques like Langendorff perfusion, molecular biology, and mass spectrometry, his lab studies experimental models of obesity, hypertension, and chemotherapy-induced cardiotoxicity. The analysis of his recent publications reveals a strong trend toward understanding oxidative stress, inflammation, and redox signaling in cardiovascular aging and disease. His work increasingly explores therapeutic applications, including natural compounds, peptide-based cardioprotection, and personalized medicine approaches in cardiovascular health. SIRC Award 2015 SIRC Award 2013 Italian Society of Physiology Award 2012 Italian Society for Cardiovascular Research Award 2011 Italian Society for Cardiovascular Research Award 2010 Italian Institute for Cardiovascular Research Award 2005 Interuniversity Consortium for Cardiovascular Research Award 2003 Angelone actively mentors PhD students and postdoctoral researchers. He has coordinated major international research projects, including the Galileo and Vinci programs, and secured funding from national and international bodies. He serves as Section Editor for the Journal of Translational Medicine and Associate Editor for multiple Frontiers journals, reflecting his significant editorial contributions. His laboratory, an operative unit of the National Institute of Cardiovascular Research (INRC), fosters collaborations with leading institutions in France (INSERM, Rouen), the USA (NIH, UC San Diego), and Italy (San Raffaele Institute, University of Turin), advancing translational cardiovascular research.

Felix Sommerمشاهده پروفایل

پژوهشگر

• Microbiome
• Host-Microbiome Interactions
• Immunology
• +۶ مورد دیگر

Felix Sommer is a Researcher and Group Leader of the Functional Host-Microbiome Research group at the Institute of Clinical Molecular Biology (IKMB) of Kiel University and University Medical Center Schleswig-Holstein (UKSH). He heads the Systems Immunology Microbiome Platform and leads the Junior Research Group Functional Host-Microbiome Research and Systems Immunology, which was established in 2020. His work focuses on understanding the intricate interactions between the host, microbiome, and environmental factors in health and disease. Felix Sommer received his PhD in cell biology in 2010 from Kiel University and completed postdoctoral training in the lab of Fredrik Bäckhed in Gothenburg, Sweden, from 2010 to 2015 before joining IKMB. His research centers on host-microbiome interactions, particularly how the microbiome influences host metabolism (such as glycolysis) and immune responses, with implications for inflammatory bowel disease, cancer, and metabolic disorders. His work employs gnotobiotic in vivo conditional knockout models, functional in vitro organoid systems, and high-throughput 'omics' technologies including next-generation sequencing and metabolomics. Analysis of his recent publications reveals a strong focus on the metabolic aspects of host-microbiome interactions, particularly how microbial metabolites influence host immune responses and disease states. His work spans multiple disease models including inflammatory bowel disease, cancer, metabolic disorders, and aging, with a consistent theme of identifying specific molecular pathways that could be targeted therapeutically. Recent work has increasingly focused on hexokinase regulation, gut barrier function, and the therapeutic potential of microbiome modulation. Felix Sommer leads a research team that includes doctoral researchers Xue Gu, Hongshu Huang, Lea Järke, Xiangyu Meng, and Saskia Weber-Stiehl. His group is supported by funding from the German Research Foundation (DFG) for the project 'Role of DUOX2 in shaping the intestinal microbiota and effects on inflammation, cancer and metabolic disease' (SO1141/10-1), the Research Group 'miTarget – The Microbiome as a Target in Inflammatory Bowel Diseases' (FOR5042), and the Excellence Cluster 'Precision Medicine in Chronic Inflammation' (EXS2167). The Functional Host-Microbiome Research group operates within the Institute of Clinical Molecular Biology at Kiel University, utilizing specialized facilities including gnotobiotic models and advanced 'omics' technologies. The group aims to develop novel strategies for treating metabolic and inflammatory disorders by targeting the intestinal microbiome through nutritional or probiotic interventions, with a particular focus on understanding the molecular mechanisms underlying host-microbiome crosstalk.

John Bainesمشاهده پروفایل

استاد

• Evolutionary Genomics
• Host-Microbiome Interactions
• Bacterial Evolution
• +۳ مورد دیگر

John Baines holds the position of Professor in Evolutionary Genomics at Kiel University (Christian-Albrechts-Universität zu Kiel) and is a Principal Investigator at the Max Planck Institute for Evolutionary Biology in Plön, Germany. Additionally, he holds an SH Excellence Chair, serves as the speaker of the Clinician Scientist Program in Evolutionary Medicine, and coordinates the Evolutionary Medicine function area within the master's program Medical Life Science at Kiel University. His laboratory is based at the Institute for Experimental Medicine (IEM) located in Kiel, where he leads research on the interplay between host evolution and microbiome dynamics. Professor Baines' research program centers on Evolutionary Genomics and Host-Microbiome Interactions, with a particular emphasis on understanding bacterial evolution in the context of chronic inflammatory diseases. His work investigates how host-microbiome metabolic interactions change with aging and disease, using mouse models to study inflammatory bowel disease, anorexia nervosa, and other conditions. He integrates genomic, metagenomic, and computational approaches to dissect the mechanisms by which host genetics and environmental factors shape the microbiome and influence disease progression and treatment outcomes. Analysis of his publication record from 2016 to 2025 shows a consistent and growing body of work in microbiome research, particularly focused on gut microbiota in health and disease. His studies frequently address the evolutionary aspects of host-microbiome co-adaptation, the impact of host genetic variation (such as in NOD2 and vitamin D receptor genes) on microbiome composition, and the clinical implications of microbiome dynamics in diverse patient populations. This research spans multiple disciplines including genomics, immunology, and computational biology, reflecting a highly interdisciplinary approach. Based on the provided information, no specific scientific awards, prizes, or fellowships are attributed to Professor Baines. However, his research is supported by competitive funding from the Deutsche Forschungsgemeinschaft (DFG), indicating recognition of his work by the scientific community. Professor Baines actively mentors students and researchers through his role in the Clinician Scientist Program and as coordinator of the Evolutionary Medicine component in the Medical Life Science master's program. His research group receives funding from the DFG for projects investigating bacterial evolution during chronic inflammation and the potential for restorative therapies based on ancestral bacterial states. These grants support a range of activities from basic research to translational applications. The Baines laboratory, part of the Evolutionary Medicine group at the Institute for Experimental Medicine, Kiel University, collaborates extensively with the Max Planck Institute for Evolutionary Biology and other institutions including the Research Center Borstel and the University Medical Center Schleswig-Holstein. Current projects, such as the investigation of bacterial evolution in inflammatory bowel disease (Phases 1 and 2 of project P10), aim to translate evolutionary insights into novel therapeutic strategies for restoring healthy microbiome states.

Paul Feinsteinمشاهده پروفایل

استاد

• Molecular Biology
• Neuroscience
• Genetics
• +۳ مورد دیگر

Paul Feinstein is a Professor in the Department of Biological Sciences at Hunter College, City University of New York (CUNY) . His research focuses on molecular mechanisms of odorant receptor gene expression, olfactory neuron development, and odor coding. He is affiliated with the Feinstein Lab , which investigates receptor genetics and sensory neuron circuitry. Ph.D., Integrated Program in Cellular, Molecular, and Biophysical Studies, Columbia University College of Physicians and Surgeons B.A. in Biochemistry, University of Pennsylvania Postdoctoral Fellow/Research Associate, The Rockefeller University Feinstein’s research explores how humans perceive odors, with key contributions to understanding odorant receptor gene choice, axon guidance, and glomerular organization in the olfactory system. His work integrates genetic engineering, molecular biology, and neurodevelopmental studies in mouse models. The 15 most recent articles highlight trends in olfactory receptor dynamics , axonal wiring , neurogenetics , and GPCR functionality . These studies span molecular imaging, gene regulation, and sensory neuron mapping, emphasizing receptor-specific mechanisms in neural circuitry. Contact: feinstein@genectr.hunter.cuny.edu | Phone: (212) 650-3169

• Bioinformatics
• Molecular Biology
• Genetics
• +۶ مورد دیگر

Dr. Ömer Faruk Karasakal is an Assistant Professor at Üsküdar University's Vocational School of Health Services, Department of Medical Laboratory Techniques. Holding a PhD in Biology from Marmara University (2021), he specializes in bioinformatics , molecular biology , and neurogenetics with a focus on in silico analysis of single nucleotide polymorphisms (SNPs) in neurodevelopmental and neurodegenerative diseases. BSc (2011) and MSc (2013) in Biochemistry from Balıkesir University Occupational Health and Safety Specialist (2013) His research explores SNP analysis in genes related to Leigh syndrome , Alzheimer's , Huntington's , and autism spectrum disorders , combining molecular docking and computational modeling . Recent work includes plant-derived SARS-CoV-2 inhibitors and oxidative stress studies in zebrafish models. He leads TÜBİTAK projects on CDH9 and SNCA gene SNPs , and serves in administrative roles including Deputy Head of Vocational Health School and Head of Department of Medical Services and Techniques. Dr. Karasakal advises graduate students in neurogenetics and computational biology while managing laboratory operations and research groups.

• Genetics
• Migraine Research
• Epilepsy Genetics
• +۳ مورد دیگر

Bridget H. Maher is a Research Fellow at Queensland University of Technology's Faculty of Health, specifically within the Institute of Health and Biomedical Innovation. She has established herself as a prominent researcher in the field of neurogenetics, with a particular focus on the genetic basis of migraine disorders and epilepsy. Her research interests span Genetics , Migraine Research , Epilepsy Genetics , Neurogenetics , Molecular Genetics , and Genomic Medicine . Dr. Maher's work primarily investigates the genetic variants associated with neurological conditions, with special attention to migraine pathophysiology and epilepsy mechanisms. She has conducted extensive research on gene polymorphisms related to migraine susceptibility, including studies on KCNK18, GRIA3, ESR1, and cytokine-related genes. Analysis of her publication record reveals a strong focus on identifying genetic markers for neurological disorders through case-control studies, genetic association analyses, and next-generation sequencing approaches. Her work often examines the role of specific genes like NRP1 in menstrual migraine, KCNA2 in epileptic encephalopathy, and SYNGAP1 in intellectual disability with epilepsy. Dr. Maher has collaborated extensively with Distinguished Professor Lyn Griffiths, a leading 'DNA detective' in the field, as evidenced by their numerous co-authored publications. Her research has been published in high-impact journals including Nature Genetics , Neurology , and Journal of Medical Genetics . While specific details about her educational background are not provided in the available materials, her extensive publication record spanning over a decade demonstrates her expertise in genetic research methodologies and neurogenetic disorders. Her work contributes significantly to understanding the molecular basis of migraine and epilepsy, potentially leading to improved diagnostic approaches and personalized treatment strategies.

Min Chenمشاهده پروفایل

استادیار

• Cancer Biology
• Lung Cancer
• Metastasis
• +۳ مورد دیگر

Min Chen, Ph.D. is an Assistant Professor in the Department of Toxicology and Cancer Biology at the University of Kentucky College of Medicine. Dr. Chen is also a member of the Markey Cancer Center/Cancer Research Priority Initiative and the Molecular and Cellular Oncology Research Program. Dr. Chen's educational background includes a Doctor of Philosophy from the University of Texas Medical (2011), a Master of Science from the Chinese Academy of Sciences (1997), and a Doctor of Medicine from Anhui Medical University (1992). Dr. Chen's research focuses on lung cancer invasion, metastasis and therapeutic resistance. Their work primarily investigates the role of integrin signaling pathways in cancer progression, with particular emphasis on Integrin α6β4 in breast and lung cancer models. Research areas include cancer cell invasion mechanisms, metastasis, therapeutic resistance, cancer epigenetics, and tryptophan metabolism in triple-negative breast cancer. The research demonstrates significant expertise in integrin biology (100%), cancer cell biology (94%), S100A4 (67%), metastatic carcinoma (45%), lung cancer (44%), tumor invasion (40%), breast cancer (40%), and lysophosphatidic acid signaling (29%). Dr. Chen's publication record demonstrates consistent contributions to cancer research, with recent articles focusing on integrin signaling pathways and their role in cancer metastasis. The research shows a strong trend toward understanding molecular mechanisms of cancer cell invasion and identifying potential therapeutic targets, particularly through the investigation of integrin α6β4 signaling in various cancer models. National Institute of General Medical Sciences: Pilot: Integrin a6ß4 Regulation of Tryptophan Metabolism in TNBC (2017-2026) National Cancer Institute: Integrin alpha6beta4 Regulation of Cancer Epigenetics (2019-2024) Army Medical Research and Materiel Command: A Novel Peptide Suppresses Invasion and Metastasis in Rictor-amplified Lung Cancer (2021-2023) KY Lung Cancer Research Fund: A Novel Peptide to Inhibit Rictor-amplified Lung Tumorigenesis (2018-2021) METAvivor Research and Support Incorporated: Characterizing Metastatic Breast Cancer Heterogeneity Through Post-Mortem Tissue Collection (2019-2020) Dr. Chen collaborates extensively with researchers across multiple institutions, particularly with Dr. Kathleen O'Connor (listed as PI on several projects where Dr. Chen is CoI), as well as Dr. Jing Liu, Dr. Chi Wang, and other members of the Markey Cancer Center. Their work contributes to UN Sustainable Development Goals related to good health and well-being through cancer research aimed at improving understanding and treatment of cancer.

• Neurobiology
• Memory Formation
• Epigenetics
• +۳ مورد دیگر

Janina Kupke is a Researcher at the Vrije Universiteit Amsterdam, affiliated with the Faculty of Science's Molecular and Cellular Neurobiology department and Amsterdam Neuroscience's research groups (Cellular & Molecular Mechanisms and Mood/Anxiety/Psychosis/Stress/Sleep). Her work focuses on molecular mechanisms underlying memory formation, epigenetic regulation (DNA methylation/DNA damage), neuronal plasticity, and aging effects on cognitive functions. Key research areas include hippocampal function in fear memory, systems consolidation, and age-related memory impairments. Her research outputs (12 articles) emphasize interdisciplinary approaches combining molecular biology, neuroscience, and genetics. Notable contributions include studies on Dnmt3a1's role in fear memory via Nrp1, Npas4's biphasic regulation of fear inhibition, and Gadd45 proteins' impact on neuronal plasticity. She also investigates aging-related cognitive decline through engram stability and stem cell quiescence mechanisms. Leveraging mouse models, her work bridges basic neurobiology with translational insights into neurodegenerative and psychiatric disorders. Collaborations span institutions globally, with active participation in high-impact journals like Neuropsychopharmacology and Molecular Psychiatry .

Baoan Jiمشاهده پروفایل

استاد

• Pancreatic Cancer Research
• Pancreatic Inflammation
• Tumorigenesis Mechanisms
• +۴ مورد دیگر

Baoan Ji, M.D., Ph.D., is a Professor of Cancer Biology and Consultant in the Department of Cancer Biology at Mayo Clinic, with a joint appointment in the Division of Gastroenterology & Hepatology. His research focuses on pancreatic inflammation, tumorigenesis, and pancreatic cancer mechanisms. He holds expertise in animal models, genetic approaches targeting pancreatic duct cells, and Aurora kinase A therapy. Key areas include dissecting Ras signaling pathways and developing clinically relevant cancer models. Education: Postdoctoral Fellowship at University of Michigan; Ph.D. in Internal Medicine-Gastroenterology from Beijing Medical University; MD from Binzhou Medical College. Research Interests: Pancreatic adenocarcinoma origins, gene manipulation in pancreatic cells, KRas mutations in cancer progression, and therapeutic strategies for inflammation-driven cancers. His work aims to translate findings into novel treatments and prevention methods. Recent studies emphasize genetic engineering techniques (e.g., CRISPR) and AI-driven body composition analysis in pancreatitis outcomes. Collaborations span hepatobiliary and gastrointestinal research fields.