Caroline Pellet-Many

Dr. Caroline Pellet-Many serves as a Senior Lecturer in Biomedical Sciences at the Royal Veterinary College (RVC), specializing in Cardiovascular Biology within the Department of Comparative Biomedical Sciences at the Camden campus. She is an active member of the Cardiovascular and Renal Biology research group and CPCS Research Programme, teaching across BVetMed and BSc Biological Sciences degrees while co-directing BSc/MSci programmes.

Academic Background:

• Undergraduate & Maitrise in Biology, Université Louis Pasteur, Strasbourg
• MSc in Physiology (Distinctions), Birkbeck College
• PhD in Cardiovascular Biology, University College London (2010)

Her research centers on gene regulation and molecular mechanisms in cardiovascular diseases, utilizing in vivo models to investigate smooth muscle cells and macrophages in atherosclerotic plaque formation. She pioneers zebrafish models for cardiac regeneration studies, examining epicardial/endocardial roles and fin regeneration for angiogenesis. Current work focuses on Neuropilins (NRP1/NRP2) in macrophage polarization during heart repair, with implications for therapeutic interventions.

Analysis of her 15 most recent publications reveals consistent focus on neuropilin signaling in cardiovascular contexts, particularly cardiac regeneration mechanisms using zebrafish models, atherosclerosis progression, and angiogenesis regulation. Key themes include receptor crosstalk (VEGFR2, PDGFR), cellular migration pathways, and inflammatory modulation in vascular disease.

Professional Recognition:

• Fellow of the Higher Education Academy

Dr. Pellet-Many supervises BSc, MSci, and PhD students including Petra Mendes-Vieira's project on neuropilins in zebrafish heart regeneration. She serves on the London Vascular Biology Forum committee and the British Small Animal Veterinary Association grant award committee, while actively promoting cardiovascular health through British Heart Foundation outreach and RVC's 'Night at the Vet College' events.

As a core member of RVC's Cardiovascular and Renal Biology group, she integrates zebrafish regeneration models with molecular techniques to investigate therapeutic targets for heart disease, emphasizing translational applications in veterinary and human medicine.