جست‌وجوی استاد و پژوهشگر

Scott Johnstoneمشاهده پروفایل

استادیار

• Cardiovascular Disease
• Cell Signaling
• Inflammation
• +۶ مورد دیگر

Scott Johnstone, Ph.D., is an Assistant Professor at the Fralin Biomedical Research Institute at Virginia Tech Carilion (VTC), the Department of Biological Sciences (College of Science), and the Department of Surgery (Virginia Tech Carilion School of Medicine). His research focuses on understanding vascular disease mechanisms, particularly how healthy blood vessels are altered in conditions like atherosclerosis and restenosis. Key areas include cell signaling pathways, pannexin channels, and connexin proteins in inflammation and proliferation. Education includes a Ph.D. and BSc from Glasgow Caledonian University, and a Postgraduate Certificate in Academic Practice from the University of Glasgow. Previous roles include postdoctoral fellowships at the University of Virginia and Glasgow Cardiovascular Research Centre. Research interests span inflammation in vascular disease, proliferation pathways in stent-induced blockages, and developing peptide inhibitors targeting connexin interactions. He also explores pannexin channels' roles in blood pressure regulation and their implications for conditions like hypertension and obesity-related vascular dysfunction. Key publications include works on pannexin 1's role in inflammation, renin secretion regulation, and endothelial dysfunction in COVID-19. Awards include the 2009 University of Virginia Outstanding Post-Doc Award and the 2004 Institute of Biomedical Science President's Prize. Led the Johnstone Lab, which collaborates on translational projects, including NIH-funded studies on obesity-heart disease links and novel therapies for vascular diseases. Lab members include postdoctoral associates and medical students like Meghan Sedovy and Adam Hoch. Active in professional activities like co-chairing international gap junction conferences and serving on advisory boards.

Thomas Kiddمشاهده پروفایل

استاد

• Neuroscience
• Developmental Biology
• Genetics
• +۳ مورد دیگر

Thomas Kidd is a Professor in the Biology Department at the University of Nevada, Reno (UNR), part of the College of Science. His research focuses on axon guidance mechanisms in Drosophila , particularly the roles of Slit proteins and Dscam1 in neural development. He has held positions at UC Berkeley (1994-1999) and Exelixis Inc. (1999-2003) before joining UNR in 2003. Kidd earned his B.A. in Genetics from Trinity College Dublin (1990) and his Ph.D. in Zoology from Oxford University (1994). Research Interests: Axon Navigation: Mechanisms of Slit-mediated repulsion/attraction, Dscam1’s role in axon branching and circuit formation Neurointestinal Development: Gut nervous system formation using feeding behavior as a readout Evolutionary Conserved Pathways: Roles of axon guidance genes in heart development, metabolism, and apoptosis Publications Highlight: Over 35 peer-reviewed articles, including seminal work on Slit/Robo/Dscam interactions (e.g., Cell , 2015; PLOS Biology , 2016). Recent studies explore apoptotic signaling’s role in axon pathfinding (2018) and Dscam1’s impact on gut nervous system function (2023). No awards listed, but his work is supported by grants focusing on neurodevelopmental mechanisms. Teaches Introduction to Neuroscience and Developmental Biology . Active in developing Drosophila genetic tools for neural circuit analysis. Labs/Teams: Leads the Kidd Lab at UNR, collaborating with international groups on axon guidance and neurodevelopmental disorders.

Julia Brenmoehlمشاهده پروفایل

پژوهشگر

• Endocrinology
• Energy Metabolism
• Cell Signaling
• +۳ مورد دیگر

Dr. Julia Brenmoehl is a researcher at the Research Institute for Farm Animal Biology (FBN), leading the working group on Endocrinology of Farm Animals. Her work focuses on energy metabolism control and cell signaling in farm animals. She has been affiliated with FBN since 2009, contributing to interdisciplinary studies on metabolic adaptations, hormonal regulation, and molecular mechanisms in animal physiology. Education: Brenmoehl earned her PhD (Dr. rer. nat.) in 2007 from the University of Jena. Her postgraduate studies included research at the Universities of Regensburg and Rostock, with prior biotechnology training at the University of Applied Sciences Jena. Her career spans clinical and academic roles, including positions at University Hospitals Jena and Regensburg, focusing on gastroenterology and endocrinology. Research Interests: Brenmoehl’s studies emphasize metabolic flexibility, lipid-glucose crosstalk, and hormonal effects on energy pathways. Her work integrates animal models (e.g., marathon mice) to investigate how genetic selection and environmental factors influence metabolic traits. Key themes include lactate metabolism, insulin-like growth factor systems, and the role of dietary interventions in obesity management. Publications: Her articles (15+ in 2021–2025) explore topics like dexamethasone’s impact on porcine leukocytes, PI3K-AKT signaling in granulosa cells, and temperature effects on sturgeon larvae metabolism. Themes include metabolic pathway modeling, dietary isoflavone effects, and exercise-induced physiological adaptations. Funding & Collaborations: Collaborations with institutions like Leibniz Institute and international teams reflect her interdisciplinary approach. She contributes to projects on animal health, genetic diversity of livestock, and biomarker development for metabolic disorders. Labs/Teams: Active in FBN’s Endocrinology group, she leverages state-of-the-art facilities for molecular biology, animal physiology, and bioinformatics analyses.

• Growth and Metabolism
• Functional Genomics
• Biomarker Research
• +۳ مورد دیگر

Andreas Höflich is a Lecturer at the University of Rostock and serves as Head of the Endocrinology of Farm Animals working group at the Research Institute for Farm Animal Biology (FBN). His research focuses on growth and metabolism, functional genome analysis, and biomarker research in farm animals. He holds a habilitation in natural sciences (2009) and veterinary medicine (2002), with a PhD from Technical University of Munich (1995). He has led the Mouse Genetics group at FBN (2006–2012) and directed the Cell Signaling Unit at FBN since 2013. His key research interests include hormonal regulation of growth, metabolic pathways in farm animals, and applications of biomarkers. Notable work includes studies on insulin-like growth factor binding proteins (IGFBPs), metabolic flexibility in marathon mice, and hormonal signaling in dairy cow lactation. He collaborates widely, co-authoring over 150 publications since 1995, with a focus on physiological and molecular mechanisms in farm animal systems. Recent studies highlight contributions to understanding IGF system dynamics, metabolic adaptations in endurance-selected mice, and biomarker development for reproductive and metabolic health in livestock. His work bridges basic endocrinology with applied agricultural science, emphasizing translational outcomes for animal production and health.

Kerry Tuckerمشاهده پروفایل

دانشیار

• Developmental Neuroscience
• Cell Biology
• Genetics
• +۳ مورد دیگر

Kerry Tucker is an Associate Professor at the Graduate School of Biomedical Science and Engineering, University of New England. He holds a B.A. in Biochemistry from Harvard College (1990) and a Ph.D. in Biomedical Science from MIT (1997). His research focuses on the role of primary cilia in central nervous system (CNS) development and congenital disorders. He previously conducted postdoctoral research at the Max Planck Institute of Neurobiology and led a group at the University of Heidelberg from 2003 to 2013, developing fluorescent protein tools to study CNS development in mice. His work revealed primary cilia’s critical role in morphogenesis, boundary formation, and neurogenesis. Recently, he investigates postnatal phenotypes linked to cilia dysfunction and congenital heart defects. His lab collaborates internationally to model neurodevelopmental disorders like ciliopathies and congenital heart defects. Education: B.A., Biochemistry, Harvard College, 1990 Ph.D., Massachusetts Institute of Technology, 1997 Research Interests: Primary cilia in CNS development, neurogenesis, congenital heart defects, ciliopathies, and neuronal apoptosis. His lab combines genetic mouse models with imaging techniques to study cilia’s role in developmental signaling pathways, such as Sonic Hedgehog and BMP. Scientific Contributions: Over 13 publications exploring primary cilia’s role in heart development, cortical morphogenesis, and neuronal integration. Recent work bridges basic science and clinical applications, aiming to model human diseases using mouse models. Advising & Labs: Supervised at least one Ph.D. student (Lindsey Avery Fitzsimons) and leads the Tucker Lab at UNE. Collaborates with institutions globally to advance understanding of cilia in health and disease. Labs/Teams: Active in the Tucker Lab, focusing on cilia’s impact on neurodevelopment and congenital defects.

• Genetics
• Pediatrics
• Mitochondrial Diseases
• +۳ مورد دیگر

Clinical Professor Carolyn Ellaway is affiliated with the University of Sydney's Faculty of Medicine and Health, specifically within the Department of Genetic Medicine at the Children's Hospital, Westmead. Her research focuses on pediatric genetic disorders, particularly mitochondrial diseases, inborn errors of metabolism (e.g., Rett syndrome, Fabry disease), and neurodevelopmental disorders. She has contributed to clinical guidelines for mitochondrial disease management and participated in large-scale genomic medicine initiatives like the Australian Genomics Mitochondrial Flagship program. Her work spans over two decades, with publications addressing treatment efficacy (e.g., cannabidivarin for Rett syndrome epilepsy, enzyme replacement therapies), genetic biomarkers (FGF21 in mitochondrial disease), and clinical case studies (e.g., Verheij syndrome, CLPB deficiency). Ellaway has also evaluated diagnostic methods (whole exome sequencing) and contributed to understanding rare conditions like NAD(P)HX dehydratase deficiency and KIF1A-related disorders. Her research integrates clinical practice with translational science, emphasizing both molecular mechanisms and patient care standards. Notable grants include developing gene therapy for Rett syndrome and exploring cortical brain organoids for treatment discovery. She collaborates widely with Australian and international teams on metabolic disease management and genetic disorder classification.

• Vascular Biology
• Lymphatic System Development
• Transcription Factor Regulation
• +۵ مورد دیگر

Mathias Francois is a Professorial Research Fellow at the University of Sydney's School of Medical Sciences within the Faculty of Medicine and Health. He is affiliated with the Charles Perkins Centre and collaborates with international institutions like the National Institutes of Health (USA). His research focuses on vascular and lymphatic system development, particularly the roles of SOX transcription factors (SOX7, SOX17, SOX18) in embryonic morphogenesis, disease pathogenesis, and cancer metastasis. Key projects include engineering transcription factors for cell fate transitions, pharmacological modulation of SOX18 activity in tumors, and studying vascular progenitors in melanoma progression. Research interests span developmental biology, stem cell biology, and molecular mechanisms underlying vascular disorders. He investigates how transcription factors regulate blood and lymphatic vessel formation, with applications to conditions like infantile hemangioma and rare genetic vascular syndromes. His grants include funding from the NHMRC, ARC, and NIH for projects targeting vascular niches in cancer, transcription factor inhibitors, and genetic interactions in lymphangiogenesis. He currently advises two students: Mahnoor MIAN (Sox7 and cardiac imaging) and Jasmine NGUYEN (dipeptidyl peptidase 9 in lung pathogenesis). Collaborative work with labs in Sydney and overseas emphasizes interdisciplinary approaches to vascular biology and regenerative medicine.

• Gene Therapy
• Genome Editing
• Viral Vectors
• +۳ مورد دیگر

Associate Professor Samantha Ginn is a Senior Lecturer and senior researcher at the Children’s Medical Research Institute (CMRI) at the University of Sydney. She specializes in gene therapy and genome editing for genetic diseases, particularly targeting the liver and hematopoietic system using viral vectors. Her work focuses on diseases like ornithine transcarbamylase (OTC) deficiency and congenital adrenal hyperplasia. She holds roles in institutional committees, including Secretary of the Australasian Gene and Cell Therapy Society. Education: PhD in Medicine from the University of Sydney (1999). Research Interests: Development of viral vector-based therapies, genome editing tools (e.g., CRISPR), and overcoming immune barriers in gene delivery. Her studies utilize mouse models and patient-derived cells to evaluate treatment efficacy. Key themes include pediatric genetic disorders, liver regeneration, and translational medicine. Grants & Projects: Recent funding includes a Children’s Tumor Foundation grant for NF2 treatment and European Society for Paediatric Endocrinology support for congenital adrenal hyperplasia research. Projects emphasize AAV vector engineering, CRISPR-based therapies, and overcoming pre-existing immunity. Labs/Teams: Based in the Gene Therapy Research Unit at CMRI, collaborating with institutions globally on gene delivery and genetic disease correction.

• Pharmaceutical Chemistry
• Cardiovascular Diseases
• Cancer
• +۳ مورد دیگر

Thomas Grewal is an Associate Professor in Pharmaceutical Chemistry at the University of Sydney's School of Pharmacy. He holds affiliations with The Centre for Drug Discovery Innovation and The University of Sydney Nano Institute. His research focuses on membrane transport, cell signaling, and cholesterol metabolism, with applications in cancer, cardiovascular diseases, and metabolic disorders. He completed a Diplom (Honours) and PhD in Germany, followed by postdoctoral training in Canada and Germany. His career includes leadership roles at the University Hospital Eppendorf (Hamburg) and the Centre for Immunology (Sydney). He has published 95 manuscripts, including works in Cell Reports , Oncogene , and Journal of Cell Science , and has secured funding from NHMRC, National Heart Foundation, and Cure Cancer Australia. Research interests include Annexin A6 function, LDL-cholesterol regulation in cancer progression, membrane contact sites, and obesity-drug interactions. He collaborates with leading scientists globally, including teams in Barcelona, Hamburg, and Helsinki. Teaching involves coordinating fourth-year pharmacy courses and mentoring 17 MD, 12 Honours, and 4 PhD students. Awards include the 2003 Habilitation in Biochemistry and the 2008 Elizabeth Wunsch Scholarship. Current projects address anti-cancer drug efficacy in obesity, mTOR signaling in prostate cancer, and membrane contact sites in metastatic prostate cancer treatment.

• Zebrafish Genetics
• Molecular Biology
• Regenerative Medicine
• +۴ مورد دیگر

Dr. Daniel Hesselson is an Adjunct Associate Professor at the University of Sydney within the Faculty of Medicine and Health, affiliated with the Centenary Institute Cancer Medicine and Cell Biology. His research focuses on molecular mechanisms in zebrafish models, including CRISPR genome editing, cardiac development, and environmental toxicology. He has contributed to studies on vitamin D metabolism, SARS-CoV-2 biology, and PFAS exposure impacts. Education: Not explicitly stated in available texts. Research Interests: Zebrafish genetics and behavior modeling Autophagy and cellular stress responses Cardiac regeneration and developmental pathways Environmental toxin exposure effects CRISPR-based genome editing technologies Grants & Funding: 2024: Cancer Australia Grant for chemoresistant ovarian cancer research (collaborating with Prof. Cole) 2023: NHMRC Ideas Grant for directed evolution of KLF1 in cardiac repair 2022: Lambert Initiative grant for high-throughput drug discovery Labs/Teams: Collaborates extensively with the Neely Lab (cell signaling) and Cole Lab (cardiovascular research) at the Centenary Institute.

Aravind Asokanمشاهده پروفایل

استاد

• Virology
• RNA Biology
• Gene Therapy
• +۴ مورد دیگر

Aravind Asokan is a Professor in Surgery at Duke University School of Medicine, holding joint appointments in Biomedical Engineering and Molecular Genetics and Microbiology. He serves as Director of Gene Therapy and leads the Asokan Lab for Synthetic Virology & Gene Therapy, focusing on advancing viral vector engineering, gene therapy, and synthetic biology. His research integrates virology, RNA biology, and genetic engineering to address challenges in treating genetic disorders, regenerative medicine, and immunotherapy. Dr. Asokan earned his Ph.D. in 2004 from the University of North Carolina, Chapel Hill. Positions: Professor in Surgery, Director of Gene Therapy, Professor of Biomedical Engineering, Professor of Molecular Genetics and Microbiology. Research Interests: Virology, RNA Biology, Viral Engineering, Gene Therapy, Gene Editing, Regenerative Medicine. Laboratory: The Asokan Lab develops AAV vectors and synthetic RNA tools for targeted gene delivery, with applications in cardiovascular diseases, muscular dystrophy, and immune modulation. His work emphasizes cross-disciplinary approaches, including CRISPR-based systems and enhancer-driven gene therapies for tissue repair. Recent advancements include engineered AAV variants for T-cell manipulation and kidney-specific gene delivery.

Jørgen Gravningمشاهده پروفایل

استاد

• Cardiac imaging
• Cardiac biomarkers
• Cardiovascular hemodynamics
• +۳ مورد دیگر

Jørgen Gravning is a Professor at the Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, and Senior Consultant at the Department of Cardiology, Oslo University Hospital, Ullevål. He also serves as Head of the Section for Echocardiography and has held roles like Head of Section for Resident Fellows. His academic journey includes an M.D. (2005) and Ph.D. (2013) from the University of Oslo, with research focused on cardiac imaging, biomarkers, and translational cardiovascular science. Education: M.D. (Cand. Med.), Faculty of Medicine, University of Oslo (2005) Ph.D. in Medicine (2013), Thesis: "Cardioprotective Mechanisms in Ischemia-Reperfusion Injury and Heart Failure" Research Interests: His work integrates clinical and translational research, emphasizing biomarker development (e.g., troponin T, NT-proBNP), echocardiography advancements, and mechanisms of heart failure. Notable areas include obesity paradox analysis, myocardial ischemia-reperfusion injury, and therapeutic targets like CTGF/CCN2. Publications: Gravning’s articles span biomarker prognostication, echocardiographic techniques, and translational studies. Recent trends focus on multimarker strategies, obesity-cardiac interactions, and molecular mechanisms in cardiac dysfunction. Over 20 peer-reviewed papers highlight his contributions to heart failure diagnostics and treatment. Lab & Collaborations: He leads the Oslo-CCHR Lab , collaborating on clinical cardiology projects. His work bridges basic science and clinical practice, with affiliations at Oslo University Hospital and international collaborations in biomarker research.

• Mathematical Biology
• Dynamical Systems
• Medical Signal Analysis
• +۵ مورد دیگر

Philip James Aston is a Professor of Mathematics at the University of Surrey, affiliated with the School of Mathematics and Physics and the Department of Mathematics. His research focuses on dynamical systems, mathematical biology, and medical signal analysis. He holds a BSc (First Class Honours) and PhD from Brunel University, followed by a postdoc at the University of Bath. Key research interests include bifurcation theory, Lyapunov exponents, pharmacokinetics, and machine learning applications in healthcare. Notable contributions include the Symmetric Projection Attractor Reconstruction (SPAR) method for waveform analysis, used in ECG and PPG signal processing. He has secured grants, including £50,000 for wearable sensor development. His work bridges mathematics and medicine, addressing challenges in cardiovascular monitoring, genetic mutation detection, and drug efficacy modeling. He collaborates with clinicians and engineers, contributing to datasets like PTB-XL+ and advancing AI-driven diagnostics.

• Nanoparticle-Cell Interactions
• Autophagy Mechanisms
• Lung Biology
• +۲ مورد دیگر

Dr. Arnold Sipos is a part-time Research Assistant Professor in the Department of Pathology at the Keck School of Medicine, University of Southern California. He holds an MD and PhD in Pathophysiology from Semmelweis University and completed postdoctoral training in renal physiology and cellular transport mechanisms. His research examines nanoparticle interactions with lung alveolar epithelial cells, cellular processing of nanomaterials, and mechanisms of autophagy. His work combines molecular imaging, cellular models, and physiological techniques to understand how engineered particles interact with biological systems. Recent publications investigate nanoparticle-induced lysosomal dysfunction, autophagic flux kinetics, and development of novel imaging tools for cellular processes. His work has implications for nanomedicine safety and pulmonary health. Awards & Honors: Amgen Postdoctoral Excellence Award (2008) American Heart Association Fellowship (2007-2009) National Scientific Award for Medical Students, Hungary (2003) Multiple Semmelweis University research awards

• Kidney Transplantation
• Dual Organ Transplantation
• Racial Disparities in Transplantation
• +۴ مورد دیگر

Santhi Voora is a Clinical Assistant Professor at the Keck School of Medicine of the University of Southern California. She serves as Medical Director of Outpatient Kidney Transplant Services and is affiliated with the Division of Nephrology and Hypertension. Her career spans clinical practice, research, and teaching in transplantation medicine. Undergraduate: Biology, Dartmouth College Medical Degree: Pennsylvania State College of Medicine Residency: Internal Medicine, Loyola University Medical Center Fellowships: Nephrology and Transplant Nephrology, University of California San Francisco Voora's research focuses on advancing kidney transplantation through artificial intelligence tools for rejection prediction, novel immunosuppression strategies, and addressing racial disparities in transplant access. Her clinical work emphasizes living donor transplantation, dual organ transplants (liver/kidney, heart/kidney), and safety net kidney transplantation initiatives. Publications highlight her expertise in transplant critical care (2023), post-transplant management education (2019), CKD screening in veteran populations (2017), and earlier neuroscience research (2008) involving astroglial function in the central nervous system. She actively contributes to medical teaching across all levels, mentoring students, residents, and fellows. Her work integrates clinical innovation with educational leadership to improve transplant outcomes and patient care equity.