معرفی
Associate Professor Samantha Ginn is a Senior Lecturer and senior researcher at the Children’s Medical Research Institute (CMRI) at the University of Sydney. She specializes in gene therapy and genome editing for genetic diseases, particularly targeting the liver and hematopoietic system using viral vectors. Her work focuses on diseases like ornithine transcarbamylase (OTC) deficiency and congenital adrenal hyperplasia. She holds roles in institutional committees, including Secretary of the Australasian Gene and Cell Therapy Society.
Education: PhD in Medicine from the University of Sydney (1999).
Research Interests: Development of viral vector-based therapies, genome editing tools (e.g., CRISPR), and overcoming immune barriers in gene delivery. Her studies utilize mouse models and patient-derived cells to evaluate treatment efficacy. Key themes include pediatric genetic disorders, liver regeneration, and translational medicine.
Grants & Projects: Recent funding includes a Children’s Tumor Foundation grant for NF2 treatment and European Society for Paediatric Endocrinology support for congenital adrenal hyperplasia research. Projects emphasize AAV vector engineering, CRISPR-based therapies, and overcoming pre-existing immunity.
Labs/Teams: Based in the Gene Therapy Research Unit at CMRI, collaborating with institutions globally on gene delivery and genetic disease correction.
