جست‌وجوی استاد و پژوهشگر

Olivia L. Francis-Boyleمشاهده پروفایل

استادیار

• Immunology
• Hematology Oncology
• Acute Leukemia Research
• +۳ مورد دیگر

Olivia L. Francis-Boyle, PhD, is an Assistant Professor in the Schools of Pharmacy and Medicine at Loma Linda University and Principal Investigator of an independent research program. She teaches immunology and endocrinology and focuses on acute leukemia mechanisms, therapeutic development, and drug modeling. Her research employs patient-derived xenograft (PDX) models, in vitro/in vivo approaches, and high-throughput sequencing. Education: PhD in Molecular Biology, Loma Linda University (2015) MS in Biomedical Science, Walden University (2011) BS in Biology, Andrews University (2005) Research Interests: Investigating cellular/molecular mechanisms of acute leukemias (AML/ALL), evaluating therapeutic candidates (biologics, small molecules, immunotherapies), and leveraging PDX models for precision medicine. Recent Article Trends: Her work spans leukemia drug development, TSLP signaling in B-ALL, and metabolic pathways in AML. Key themes include xenograft models, therapeutic screening, and molecular mechanisms. Grants & Advising: Principal Investigator: Combination anti-PD1 therapy and TILs for AML (2020-2025) Completed grants include TSLP in pediatric B-ALL (2012-2013) and Hyundai Hope on Wheels (2015-2016) Labs & Teams: Leads a lab training students/fellows in leukemia research, collaborating on preclinical drug models and translational studies.

Patrick J. Mulhollandمشاهده پروفایل

استاد

• Neuroscience
• Addiction
• Synaptic Plasticity
• +۳ مورد دیگر

Dr. Patrick J. Mulholland is a Professor in the Department of Neuroscience at the Medical University of South Carolina (MUSC), part of the College of Medicine. He holds dual affiliations in the Departments of Neuroscience and Psychiatry & Behavioral Sciences. His research focuses on neural mechanisms underlying alcohol addiction, synaptic plasticity, and the neurotoxic effects of alcohol. Dr. Mulholland earned his PhD in Behavioral Neuroscience and Psychopharmacology from the University of Kentucky before completing postdoctoral training at MUSC. He was promoted to Associate Professor in 2015 and Professor in 2020. His research investigates how alcohol exposure alters synaptic function, particularly through glutamatergic systems and potassium channel regulation. Key areas include ethanol-induced neurotoxicity, dendritic spine adaptations, and stress-alcohol interactions. He leads components of the Charleston Alcohol Research Center, serving as PI of a research program and Co-Director of the Pilot Project Core. Dr. Mulholland’s work spans preclinical models, exploring mechanisms of alcohol dependence, relapse, and neural circuit dysregulation. Education: PhD in Behavioral Neuroscience & Psychopharmacology (University of Kentucky) Publications highlight studies on ethanol’s effects on hippocampal and cerebellar neurons, glucocorticoid interactions, and novel therapeutic targets for alcohol use disorders. His lab employs electrophysiology, slice cultures, and behavioral assays to dissect addiction-related neuroplasticity. Collaborative projects include investigating Kcnq4 channel regulation and cross-species synaptic biomarkers in heavy-drinking macaques.

Richard Wagnerمشاهده پروفایل

استاد مدعو

• Biophysics
• Membrane Biology
• Protein Transport
• +۳ مورد دیگر

Prof. Richard Wagner is an Adjunct Professor of Biophysics at the School of Science, Constructor University Bremen gGmbH. His research focuses on membrane biology, protein transport mechanisms, and ion channel function. Notable contributions include studies on mitochondrial and chloroplast protein translocation channels, lipid bilayer dynamics, and the structural analysis of pore-forming proteins. Key research areas include: Characterization of mitochondrial import pores (Tom40, Tim23) Analysis of chloroplast envelope channels (Toc75, OEP proteins) Development of microfluidic techniques for membrane protein analysis Investigation of antibiotic permeation through bacterial porins His work integrates electrophysiology, single-molecule imaging, and computational modeling to study membrane transport at molecular resolution. Over 200 peer-reviewed publications demonstrate contributions to understanding cellular organelle protein import pathways and nanopore-based biophysical systems.

Klaus Ebnetمشاهده پروفایل

استاد

• Cell Adhesion
• Cell Polarity
• Junctional Adhesion Molecules (JAMs)
• +۵ مورد دیگر

Prof. Dr. Klaus Ebnet is a Full Professor at the University of Muenster, leading the Ebnet Lab: Cell Adhesion and Cell Polarity within the Center for Molecular Biology of Inflammation (ZMBE). His work focuses on understanding molecular mechanisms of cell-cell interactions, cell polarity establishment, and adhesion molecule functions such as Junctional Adhesion Molecules (JAMs) and integrins. He holds a position in the Institute of Medical Biochemistry and participates in the 'Cells in Motion' research initiative. Research Interests: Regulation of epithelial cell polarity via adhesion receptors JAM-A-integrin signaling complexes in cell migration Role of TMIGD1 in microvillus formation and mitochondrial interactions Mechanical regulation of tight junction assembly Cell adhesion dynamics in angiogenesis and cancer metastasis Publications (selected 2022-2012): Focus on molecular mechanisms of cell adhesion, polarity maintenance, and their disruption in disease contexts. Highlights include discoveries about JAM-A's role in spindle orientation during mitosis, integrin cross-talk in collective cell migration, and the TMIGD1-based adhesion complex in intestinal development. Labs/Teams: Leads the Ebnet Lab at ZMBE, collaborating in interdisciplinary imaging networks. Active in training graduate students through the 'Cells in Motion' graduate school program.

Venuprasad Poojaryمشاهده پروفایل

دانشیار

• Immunology
• Gastrointestinal Disorders
• Inflammation Regulation
• +۳ مورد دیگر

Venuprasad Poojary, Ph.D., is an Associate Professor in the Departments of Internal Medicine and Immunology at UT Southwestern Medical Center and a member of the Division of Digestive and Liver Diseases. He joined the faculty in 2019. His research focuses on regulatory mechanisms of immune cells in gastrointestinal inflammation and cancer, with a goal to identify therapeutic targets for chronic inflammatory diseases. Education: B.Sc. in Biochemistry (Mangalore University), M.Sc. in Bioscience (Mangalore University), Ph.D. in Immunology (National Center for Cell Science, Kolkata). Postdoctoral training at La Jolla Institute for Allergy and Immunology (San Diego). Research interests include Th17 cell regulation, RORγt signaling, mitochondrial dysfunction in inflammation, and immunotherapeutic approaches for intestinal disorders. His lab investigates mechanisms linking inflammation to cancer and autoimmune conditions, with recent work on protein modifications and mitochondrial pathways. Publications span topics like colonic inflammation, T-cell exhaustion, and Wnt/β-catenin inhibition, emphasizing translational research. He is affiliated with professional organizations including the American Association of Immunologists and American Association for Cancer Research. Led by Dr. Poojary, the Poojary Research Lab collaborates on projects addressing immune checkpoints and therapeutic development. No specific grants or advisees are listed, but the lab actively engages in collaborative research initiatives.

Dayoung Ohمشاهده پروفایل

استادیار

• G protein-coupled receptors (GPCRs)
• Metabolic syndrome
• Type 2 diabetes
• +۳ مورد دیگر

Dayoung Oh is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Touchstone Diabetes Center. She holds a Ph.D. in molecular endocrinology and completed postdoctoral training at UC San Diego under Jerrold Olefsky. Her research focuses on G protein-coupled receptors (GPCRs), particularly GPR120, in metabolic syndromes like obesity, type 2 diabetes, and chronic inflammation. She employs biochemical and physiological approaches, including GPCR knockout models and cell-based studies, to elucidate molecular mechanisms and identify therapeutic targets. Education: Ph.D. in molecular endocrinology (university unspecified), postdoctoral training at UC San Diego. Research Interests: GPCR signaling pathways, orphan GPCR ligand identification, omega-3 fatty acid receptor function, macrophage-mediated inflammation, insulin resistance, and metabolic syndrome pathophysiology. Her work bridges basic science and translational research, aiming to improve metabolic health through GPCR-targeted therapies. Teaching and Service: Teaches at the Graduate School of Biomedical Sciences and serves on committees for the Molecular Metabolism and Metabolic Diseases Program. Labs and Affiliations: Leads the Oh Laboratory at UT Southwestern and collaborates within the Touchstone Diabetes Center. Research emphasizes GPCR-driven metabolic processes and therapeutic innovations.

• Aquatic Parasitology
• Finfish Health and Welfare
• Disease Modeling
• +۵ مورد دیگر

Professor James Bron is a Professor of Aquatic Animal Health and Head of the Aquatic Parasitology Research Group at the University of Stirling's Institute of Aquaculture. He holds a BSc in Zoology with Marine Zoology (University of North Wales, Bangor), an MSc in Bioarchaeology (University College London), and a PhD from the University of Stirling (1987). His career spans over 30 years focused on aquatic parasitology, finfish health, and disease control in aquaculture. He leads interdisciplinary research on sea lice, bacterial/viral pathogens, and gill diseases (e.g., AGD), emphasizing applied solutions such as vaccines, genetic resistance, and engineering interventions. His work integrates microscopy (SEM/TEM/confocal), modeling, and functional feed development, with funding from BBSRC, EU Horizon, and industry partners. He collaborates globally on projects addressing sustainable aquaculture challenges. Research Interests: Sea lice biology and control mechanisms Genetic resistance to pathogens Immunological responses in fish Novel treatments and diagnostics Functional feed development Key Contributions: Over 150 publications and 18 research projects. His team pioneered studies on sea lice resistance to chemicals, developed imaging techniques for parasite detection, and advanced genomic approaches for disease management. He chairs the Aquaculture Health group and advises on EU regulatory frameworks for aquatic pathogens.

Guoying Bingمشاهده پروفایل

استاد

• Neuroinflammation
• Neurodegenerative Diseases
• Parkinson's Disease
• +۴ مورد دیگر

Guoying Bing is a Professor in the Department of Neuroscience at the University of Kentucky's College of Medicine. Her research focuses on neuroinflammatory mechanisms in neurodegenerative diseases, particularly Parkinson's disease (PD) and Alzheimer's disease (AD). Institution: University of Kentucky, College of Medicine Department: Neuroscience Academic Rank: Professor Research Interests: Dr. Bing investigates how microglial activation and xenobiotic metabolites contribute to dopaminergic cell death in PD models, and the role of microsomal epoxide hydrolase (mEH) in neurodegeneration. Current work explores mitochondrial dysfunction, oxidative stress, and neuroinflammatory pathways. Publication Trends: Recent studies examine neurotoxicity from environmental chemicals (e.g., trichloroethylene, chlorpyrifos), glial-neuronal interactions, and therapeutic agents like pioglitazone and ginsenosides. Keywords span Mitochondrial Bioenergetics , Neuroinflammation , and Xenobiotic Metabolism . Laboratory Work: Her lab has developed LPS injection models for PD and studied mEH's dual role in activating/inactivating neurotoxic compounds. Collaborative studies involve neurodegenerative signaling pathways (e.g., NF-κB, JNK, PPARγ) and neuroprotective strategies.

• Redox Biology
• Biochemistry
• Oxidative Stress
• +۵ مورد دیگر

Leslie B. Poole serves as Professor in the Department of Biochemistry at Wake Forest School of Medicine, Wake Forest University, where she has been faculty since 1992. She holds leadership roles as Director of the Center for Structural Biology and Co-Director of the Center for Redox Biology & Medicine, contributing significantly to institutional research infrastructure and scientific community engagement. Her educational background includes: B.A. in Biology & Chemistry, Wake Forest University (1980) Ph.D. in Biochemistry, Wake Forest University (1988) Postdoctoral Fellowship, University of Maryland-College Park (1988-1991) Dr. Poole is an internationally recognized expert in redox biology , specializing in oxidation/reduction control of protein and enzyme function. Her pioneering work defined the chemistry of biological thiol redox reactions and established hydrogen peroxide as a critical signaling molecule. Her research bridges biochemistry , cancer biology , and translational medicine , with applications in developing novel therapeutics and diagnostic tools for oxidative stress-related diseases. Current investigations focus on redox regulation in cancer progression, cardiotoxicity of chemotherapeutics, and mitochondrial oxidative stress mechanisms. Analysis of her recent publications (2022-2025) reveals persistent emphasis on peroxiredoxin function, protein sulfenylation detection, and redox-mediated signaling in cancer and inflammation. Key trends include therapeutic targeting of redox vulnerabilities in KRAS-mutant cancers, mitochondrial redox control of immune responses, and innovative approaches to mitigate chemotherapy-induced cardiotoxicity through redox modulation. Her scientific recognition includes: 2024 WFU Friends of Chemistry Distinguished Alumni Award Dr. Poole has secured over $16 million in extramural funding (94% from NIH), demonstrating exceptional grant-writing success. She has mentored numerous graduate students and postdoctoral fellows while leading collaborative research initiatives. Her administrative contributions span university committees including safety oversight and Women in Medicine & Science advocacy. She directs the Center for Structural Biology and co-directs the Center for Redox Biology & Medicine, where her team develops redox-based detection technologies including the patented platform commercialized through Xoder Tech, LLC, a Women Owned Small Business she co-founded.

Christian Zörbمشاهده پروفایل

استاد

• Crop Plants
• Abiotic Stress Physiology
• Viticulture
• +۴ مورد دیگر

Prof. Christian Zörb serves as Professor of Quality of Plant Products and Viticulture at the University of Hohenheim's Faculty of Agricultural Sciences. As Head of the Quality of Plant Products Department and Deputy Director of the Institute of Crop Sciences, his work bridges plant physiology, agricultural chemistry, and sustainable farming practices. His educational background includes a PhD (1998) and Habilitation (2007) from Justus Liebig University Giessen, followed by postdoctoral research across Europe and the US. He has held academic positions at the University of Leipzig (2012–2014) and the University of Sussex (2012–2013), before assuming his current role in 2014. Research interests focus on Crop stress physiology under climate change Nutrient management in viticulture and cereal crops Quality aspects of wheat and onion storage Phytoremediation strategies using legumes Guard cell signaling mechanisms in drought tolerance His work emphasizes translational research between lab-scale studies and field applications, with over 100 peer-reviewed articles exploring topics like nitrogen fertilization effects on wheat quality, microbiome dynamics in agroforestry systems, and cryo-FIB-SEM imaging of plant ultrastructure. Collaborations span institutions in Germany, the UK, and the US. Current projects include investigating salt stress responses in crops, optimizing grapevine training systems for metabolomic signatures, and evaluating heirloom onion varieties for organic agriculture. His lab integrates near-infrared spectroscopy for real-time quality analysis and develops predictive models for climate-smart agricultural practices.

• Metabolic Health
• Exercise Physiology
• Diabetes Management
• +۳ مورد دیگر

Sophie Broome is a Postdoctoral Research Fellow at the Mary MacKillop Institute for Health Research within the Faculty of Health Sciences. Her research focuses on metabolic health, exercise physiology, and the interplay between nutrition, exercise, and chronic diseases such as Type 2 Diabetes. She investigates mechanisms related to insulin resistance, mitochondrial function, and the effects of antioxidants on muscle recovery and performance. Her research interests center on understanding how dietary interventions, exercise, and mitochondrial-targeted antioxidants influence metabolic health. Key areas include the role of β-catenin in skeletal muscle insulin resistance, the efficacy of time-restricted eating combined with exercise in managing blood glucose levels, and the impact of mitochondria-targeted antioxidants on muscle recovery and athletic performance. Recent studies have explored topics such as lifespan extension in mice via PI3K inhibitors and the lack of effect of antioxidants on muscle soreness post-exercise. Her work often employs randomized controlled trials and animal models to evaluate intervention efficacy. Broome’s publications span journals in diabetes research, aging biology, and exercise physiology, reflecting her interdisciplinary approach to metabolic health and muscle function. She is affiliated with the Mary MacKillop Institute for Health Research and contributes to collaborative projects within the Faculty of Health Sciences.

Priyanka Singhمشاهده پروفایل

پژوهشگر ارشد

• Nanotechnology
• Green Synthesis of Nanoparticles
• Antibacterial Applications
• +۵ مورد دیگر

Priyanka Singh is a Senior Researcher at the Novo Nordisk Foundation Center for Biosustainability (Technical University of Denmark, Denmark), focusing on nanotechnology and bacterial signal transduction. Her work bridges Nanomaterials , Pharmacology , and Biosustainability , contributing to UN Sustainable Development Goals. Expertise : Green synthesis of nanoparticles, antimicrobial applications, cancer therapy, and biofilm inhibition. Collaborations : Frequent co-authorship with researchers like Ivan Mijakovic and others in multidisciplinary teams. Her recent publications highlight oncological nanomaterials (gold, silver, iron oxide nanoparticles), eco-friendly wound dressings , and antibacterial strategies using plant/microbial extracts. Research trends emphasize green chemistry , targeted therapies , and cross-disciplinary applications in medicine and agriculture.

Allen W. Cowley, Jr.مشاهده پروفایل

استاد

• Cardiovascular Physiology
• Genetics and Genomics
• Renal Physiology
• +۴ مورد دیگر

Allen W. Cowley, Jr. is the Harry & Gertrude Hack Term Professor and Chair of the Department of Physiology at the Medical College of Wisconsin since 1980. He holds a PhD in Physiology from Hahnemann Medical University (1968) and a BA in Economics from Trinity College (1961). His research focuses on cardiovascular and renal physiology, hypertension mechanisms, and physiological genomics, with over 325 peer-reviewed publications and continuous NIH funding since 1971. **Research Interests**: Dr. Cowley pioneered studies on baroreceptor reflexes, renin-angiotensin system, renal medullary circulation, and hypertension genetics. His work demonstrated how reduced renal medullary blood flow contributes to chronic hypertension, and he advanced the field of physiological genomics by linking genetic variants to complex diseases. He leads two NIH-funded programs: one on kidney-based blood pressure control and another on salt-sensitive hypertension genetics. **Awards & Leadership**: He served as APS President, IUPS President, and AHA Council Chair. His honors include the Walter Cannon, Ernest Starling, and Carl Wiggers Awards (APS), Novartis Award, and AHA Distinguished Scientist Award. **Advising & Grants**: He has mentored over 50 trainees and directs NIH program projects. His lab explores oxidative stress in hypertension, renal injury mechanisms, and metabolic responses to high salt intake. **Labs/Teams**: His laboratory integrates systems biology, genomics, and experimental physiology to uncover genetic and molecular bases of hypertension and renal dysfunction.

Ioannis Patrikiosمشاهده پروفایل

استاد

• Biochemistry
• Multiple Sclerosis Treatment
• Neurology
• +۴ مورد دیگر

Ioannis Patrikios is a Professor of Biochemistry and Deputy Dean at the School of Medicine, European University Cyprus. He holds a Ph.D. in Biochemistry from The City University of New York (1994) and a BSc in Biochemistry (1986). His research focuses on biochemistry, multiple sclerosis treatment (particularly Neuroaspis PLP10), anticancer agents, omega fatty acids, and clinical trials. He leads Phase III clinical trials for neurodegenerative diseases and has pioneered nutraceutical interventions for MS. Awards include the Forensic Fellows of Medical Science (2015), Scuola Superiore d'Immunologia Fellowship (2001), and Sigma Xi Honor Society membership (1994). Founder and Chairman of the School of Medicine at European University Cyprus Former CEO of PALUPA Medical Ltd., developing therapeutic nutraceuticals Editor of EC Neurology and advisor to the Academy of Forensic Medical Sciences Key research areas: Neuroprotective agents, MS treatment efficacy, clinical trial methodologies, and lipid agglutination mechanisms. His work includes over 50 peer-reviewed publications and patents on medical nutrition formulas. He organizes annual international biomedical congresses in Cyprus and has contributed to European Union-funded projects like Gender Net (2019). Exhibitions and clinical trials focus on Neuroaspis PLP10 for MS therapy, showcased at international forums since 2016. His research bridges basic biochemistry with clinical applications, emphasizing translational medicine.

• Neurotoxicology
• Neurodegenerative Diseases
• Environmental Health
• +۳ مورد دیگر

Jason Richardson is the Dianne Isakson Distinguished Professor in the Department of Physiology and Pharmacology at the University of Georgia’s College of Veterinary Medicine, where he leads the Isakson Center for Neurological Disease Research. His research focuses on environmental chemical exposures and genetic susceptibility as contributors to neurological diseases such as Alzheimer’s and Parkinson’s. Key areas include neurotoxicology, translational approaches to disease mechanisms, and the impact of pesticide exposure across lifespans. Research Interests: Dr. Richardson investigates how pesticides and heavy metals interact with genetic factors to drive neurodegenerative processes. His work integrates animal models, omics technologies, and epidemiological data to uncover pathways linking environmental toxins to amyloid pathology, neuroinflammation, and neuronal dysfunction. Scientific Contributions: Highlighted the role of DDT and manganese in accelerating Alzheimer’s pathology in mice. Linked prenatal pesticide exposure to midlife cognitive decline and amyloid biomarkers. Explored exercise as a neuroprotective strategy in Parkinson’s models. Awards: Holds the endowed Dianne Isakson Distinguished Professorship. Labs/Teams: His work is conducted through the Isakson Center, focusing on interdisciplinary collaborations in neurotoxicology and translational neuroscience.