معرفی
Prof. Dr. Klaus Ebnet is a Full Professor at the University of Muenster, leading the Ebnet Lab: Cell Adhesion and Cell Polarity within the Center for Molecular Biology of Inflammation (ZMBE). His work focuses on understanding molecular mechanisms of cell-cell interactions, cell polarity establishment, and adhesion molecule functions such as Junctional Adhesion Molecules (JAMs) and integrins. He holds a position in the Institute of Medical Biochemistry and participates in the 'Cells in Motion' research initiative.
Research Interests:
- Regulation of epithelial cell polarity via adhesion receptors
- JAM-A-integrin signaling complexes in cell migration
- Role of TMIGD1 in microvillus formation and mitochondrial interactions
- Mechanical regulation of tight junction assembly
- Cell adhesion dynamics in angiogenesis and cancer metastasis
Publications (selected 2022-2012): Focus on molecular mechanisms of cell adhesion, polarity maintenance, and their disruption in disease contexts. Highlights include discoveries about JAM-A's role in spindle orientation during mitosis, integrin cross-talk in collective cell migration, and the TMIGD1-based adhesion complex in intestinal development.
Labs/Teams: Leads the Ebnet Lab at ZMBE, collaborating in interdisciplinary imaging networks. Active in training graduate students through the 'Cells in Motion' graduate school program.
