جست‌وجوی استاد و پژوهشگر

Mike Ryanمشاهده پروفایل

استاد

• Mitochondrial Biology
• Mitochondrial Disease
• Biochemistry
• +۱۷ مورد دیگر

Professor Mike Ryan is a leading academic and research leader at Monash University, where he serves as Interim Deputy Vice-Chancellor (Research) and Senior Vice-President, and as Head of the Mitochondrial Biology and Disease Laboratory in the Monash Biomedicine Discovery Institute (BDI), within the Faculty of Medicine, Nursing and Health Sciences and the Department of Biochemistry and Molecular Biology. He holds a Bachelor of Science (Honours) and PhD in Biochemistry from La Trobe University and was previously Head of the Department of Biochemistry at La Trobe University. He was an Alexander von Humboldt Fellow at the University of Freiburg, Germany, and served as Pro Vice-Chancellor (Research) at Monash before his current leadership role. Professor Ryan's research is centered on mitochondrial biology, particularly mitochondrial disease, dynamics, and the molecular basis of disorders affecting oxidative phosphorylation. His lab uses gene editing, proteomics, and mouse models to study mitochondrial protein function and disease mechanisms. He leads major projects on Complex I dysfunction, mitochondrial dynamics, the MICOS complex, and mtDNA release. His work contributes to the UN Sustainable Development Goals through biomedical discovery. His recent publications demonstrate a strong focus on mitochondrial fission/fusion, OXPHOS assembly, and the role of mitochondria in cell death and disease. Articles in Nature , Cell Metabolism , and PNAS highlight his lab’s impact on understanding mitochondrial dynamics, Complex I and IV assembly, and metabolic reprogramming. ASBMB Lemberg Medal (2023) Roche Medal, ASBMB (2006) President, ASBMB (2015–2016) Chair, International Human Frontier Science Program Research Grant Committee Board Member and Chair of Scientific and Medical Advisory Panel, Mito Foundation Professor Ryan has advised numerous PhD and postdoctoral researchers, including current group leaders Dr. Luke Formosa and Dr. Kate McArthur. His lab collaborates nationally and internationally, with funding from NHMRC, ARC, MRFF, and the Mito Foundation. He is actively involved in graduate research programs and is accepting new PhD students through Supervisor Connect. The Ryan Lab is a key member of the Metabolism, Diabetes & Obesity and Neuroscience Programs at the BDI, fostering interdisciplinary research. The lab employs advanced techniques including CRISPR/Cas9, BN-PAGE, mass spectrometry, and live-cell imaging to investigate mitochondrial function and disease.

Paul A. Cobineمشاهده پروفایل

استاد

• Metal Homeostasis
• Mitochondrial Biology
• Copper Transport
• +۷ مورد دیگر

Paul A. Cobine is the Lawrence C. Wit Professor and Chair of the Department of Biological Sciences at Auburn University, where he leads an active research program in metal ion homeostasis and mitochondrial biology. He teaches undergraduate and graduate courses including General Microbiology, Clinical Microbiology, and Model Systems and Disease. Ph.D., The University of Queensland, Australia (2004) Postdoctoral Fellow, University of Utah (2007) B.S., The University of Queensland, Australia (1996) His research focuses on the mechanisms of copper and iron distribution in mitochondria, using Saccharomyces cerevisiae and the plant pathogen Xylella fastidiosa as model systems. He investigates how metals are transported, stored, and utilized in organelles, with implications for human diseases such as mitochondrial disorders and neurodegeneration, as well as agricultural diseases like Pierce’s disease in grapes. The recent publications highlight a strong trend in mitochondrial copper transport (e.g., SLC25A3/Pic2), copper-induced cell death (cuproptosis), and the role of metal homeostasis in plant pathogenesis. His work bridges biochemistry, genetics, and physiology, with applications in both medicine and agriculture. Notable scientific contributions include identifying mitochondrial carriers as copper transporters and elucidating metal-dependent virulence mechanisms in X. fastidiosa . His lab is supported by NIH and NIFA grants. He has mentored numerous graduate and undergraduate students, many of whom have completed theses on mitochondrial copper, iron metabolism, and bacterial ionomics. His lab collaborates with researchers at the University of Saskatchewan and within Auburn University’s Department of Entomology and Plant Pathology. Research in the Cobine Lab spans three main areas: mitochondrial copper in yeast, mitochondrial copper in mammalian cells, and ionomics of plant disease caused by X. fastidiosa , aiming to understand how metals influence cellular function and disease progression.

• Probability theory and stochastic processes
• Random differential equations
• Uncertainty quantification
• +۶ مورد دیگر

Ana Navarro Quiles is an Associate Professor in the Department of Statistics and Operations Research at the Faculty of Mathematics, University of Valencia, Spain. She is a member of the PROMEDyA research group, focusing on prediction and optimization under uncertainty using dynamic stochastic models. PhD : Universitat Politècnica de València, 2018 Thesis : Computational Methods for Random Differential Equations: Theory and Applications Supervisors : Dr. Juan Carlos Cortés López, Dr. Rafael Villanueva Micó, Dr. María Dolores Roselló Ferragud Her research centers on probabilistic solutions of random differential equations, uncertainty quantification in biological and epidemiological models, and stochastic control systems. She employs advanced techniques such as the Random Variable Transformation (RVT) method and Karhunen-Loève expansion to analyze systems with random parameters. Her work bridges theoretical mathematics with real-world applications in public health, chemistry, and engineering. She has published extensively in journals like Journal of Computational and Applied Mathematics and Chaos, Solitons & Fractals . The recent publications reveal a strong trend toward modeling complex dynamical systems under full parametric uncertainty, particularly in biological growth (Gompertz, logistic) and disease spread (SIR-type models). Her methodological focus lies in deriving complete probabilistic solutions using transformation techniques and functional expansions, moving beyond mean-value approximations to capture full distributional behavior. No scientific awards are mentioned in the provided texts. Ana Navarro Quiles collaborates extensively with researchers from the Universitat Politècnica de València and other institutions. While no specific grants are listed, her sustained output suggests active funding support. She has not been explicitly mentioned as an advisor to students in the provided material, but her role in a PhD thesis as a supervisor's co-supervisee indicates strong mentoring experience. She is affiliated with the PROMEDyA research group (Prediction and Optimization under uncertainty: dynamic stochastic models and applications), which conducts interdisciplinary research on modeling uncertain dynamical systems with applications in science and engineering.

Zhihao Wuمشاهده پروفایل

استادیار

• Neuroscience
• Gene Regulation
• Mitochondrial Biology
• +۴ مورد دیگر

Dr. Zhihao Wu is an Assistant Professor at the Department of Biological Sciences, Southern Methodist University (SMU), with a focus on neuroscience and gene regulation. His research investigates cellular quality control systems in age-related neurological diseases. Education: Ph.D. from Tsinghua University, Postdoc at Stanford School of Medicine Research Interests: Dr. Wu's work connects ribosome-associated translation quality control, macromolecule quality control, and mitochondrial quality control to understand proteostasis failure in neurodegenerative diseases. His lab employs Drosophila melanogaster models and mammalian systems. Publications Trend: Recent work focuses on: Mitochondrial stress responses in glioblastoma (2025) Ribosomal recycling complex in mitochondrial dynamics (2025) CNOT4-ZNF598 pathway in tissue homeostasis (2024) Mitochondrial-ER tethering mechanisms (2024) Novel therapeutic strategies for neurodegeneration (2023) Laboratory: Located in DLSB 217, Lab Tel: 214-768-1660

Antentor O Hinton, Jr.مشاهده پروفایل

استادیار

• Mitochondrial Biology
• Cellular Morphology
• Molecular Physiology
• +۶ مورد دیگر

Dr. Antentor O Hinton, Jr. is an Assistant Professor in the Department of Molecular Physiology and Biophysics at Vanderbilt University School of Medicine. His primary affiliation is with the Hinton Lab, which focuses on molecular mechanisms regulating mitochondrial-endoplasmic reticulum interactions. Research employs advanced microscopy techniques such as Serial Block Face (SBF)-SEM and Focus Ion Beam (FIB)-SEM. Research specialties include studying how molecule transfer and morphological changes between mitochondria and ER are altered in pathophysiological conditions like diabetes, obesity, and cardiovascular disease. Key molecular targets include TMEM135 and MICOS complexes. No specific publications or awards were explicitly listed in the provided materials. The lab's website (currently unavailable) likely contains further details about ongoing projects and collaborations.

Jonathan Friedmanمشاهده پروفایل

استادیار

• Radiology
• Pediatric Radiology
• Mitochondrial Biology
• +۴ مورد دیگر

Jonathan Friedman, M.D., is an Assistant Professor of Radiology at UT Southwestern Medical Center and a member of its Pediatric Radiology Division. He completed his undergraduate studies in Biology and Business Foundations at the University of Texas at Austin, earned his medical degree from Tulane University School of Medicine, and completed his radiology residency and fellowships in neuroradiology and pediatric radiology at UT Southwestern. His research focuses on mitochondrial biology, cellular migration, and ER-mitochondrial interactions, with recent work exploring mitophagy mechanisms and organelle crosstalk. Dr. Friedman is deeply committed to service, leading initiatives like the Radiology Department's Global Health Initiative providing teleradiology services to Haiti. He has volunteered with Camp Dream Street, Kingsley House, and Big Brothers Big Sisters. Professional affiliations include the American College of Radiology, Texas Radiological Society, and Society for Pediatric Radiology. His research trends emphasize mitochondrial dynamics and molecular mechanisms, with a growing focus on translational applications in pediatric radiology. Over 15 key articles span imaging technology improvements and foundational cell biology studies.

Martin van der Laanمشاهده پروفایل

استاد

• Mitochondrial biogenesis
• Mitochondrial ultrastructure
• Membrane dynamics
• +۴ مورد دیگر

Prof. Dr. Martin van der Laan is a Professor of Medical Biochemistry & Molecular Biology at Saarland University, where he leads a research group within the Center for Molecular Signaling (PZMS) at the University Medical Center in Homburg. His work focuses on mitochondrial biology, particularly the biogenesis, ultrastructure, and functional dynamics of these essential cellular organelles. Dr. van der Laan's research interests span several interconnected areas of mitochondrial biology: The nano-architecture and spatio-temporal regulation of the mitochondrial inner membrane The structure, function, and regulation of membrane contact sites Mitochondrial protein import and sorting mechanisms The role of mitochondria in cellular metabolism and stress responses Mitochondrial dynamics and their implications for human health and disease Analysis of Dr. van der Laan's recent publications (2018-2023) reveals a consistent focus on mitochondrial structure and function, with particular emphasis on the MICOS complex (Mitochondrial Contact Site and Cristae Organizing System), protein import machinery (particularly the TIM23 complex), and the relationship between mitochondrial architecture and cellular metabolism. His work combines structural, biochemical, and cell biological approaches to understand fundamental mechanisms of mitochondrial biology, with implications for understanding metabolic disorders and diseases. Dr. van der Laan's research is supported by multiple funding sources, including the IRTG 1830, Barth Syndrome Foundation, BIF, and COMM. His laboratory employs a range of biochemical, genetic, and cell biological methods and maintains numerous local, national, and international collaborations. The research group led by Dr. van der Laan is part of the Center for Molecular Signaling and focuses on understanding the fundamental molecular mechanisms of mitochondrial biology in the context of metabolic adaptation, cellular stress responses, and cell differentiation.

Matam Vijay-Kumarمشاهده پروفایل

استاد

• Host Metabolic Adaptations to Inflammation
• Gut Microbiota
• Innate Immunity
• +۳ مورد دیگر

Matam Vijay-Kumar is a Professor at the University of Toledo, where he directs the University of Toledo-Microbiome Consortium (UT-MiCo). His research explores the complex interplay between host innate immunity, gut microbiota, and metabolic disorders, with a focus on Toll-like receptor 5 (TLR5) deficiency, neutrophil extracellular traps (NETs), and dietary influences on hypertension and liver disease. He earned a Ph.D. in Biochemistry from Central Food Technological Research Institute, Mysore, India. Ph.D., Biochemistry, Central Food Technological Research Institute, Mysore, India (2002) His work demonstrates how metabolic adaptations to gut inflammation can paradoxically protect against pathogens while promoting metabolic syndromes. Current projects investigate microbiota-dependent mechanisms in liver cancer, bile acid signaling, and the impact of dietary fibers on inflammatory and cardiovascular diseases. His recent publications highlight trends in microbiome research, including glyphosate-induced hypertension, TGR5 signaling, and epigenetic effects of ketone bodies. Notably, he received the 2019 Harriet Dustan Award for his work on metabolites and hypertension. 2019 Harriet Dustan Award