جست‌وجوی استاد و پژوهشگر

Kevin Parkمشاهده پروفایل

استاد

• Neuroscience
• Ophthalmology
• Axon Regeneration
• +۳ مورد دیگر

Dr. Kevin Park is a Professor of Ophthalmology and Neuroscience at UT Southwestern Medical Center. His research focuses on mechanisms underlying neuronal circuit formation in the visual system and the cellular/molecular basis of neurodegeneration, particularly in glaucoma and retinitis pigmentosa. He holds a Ph.D. in Anatomy and Human Biology and a B.Sc. in Biochemistry and Microbiology from the University of Western Australia. Previously, he was a postdoctoral fellow at Harvard University and faculty at the University of Miami Miller School of Medicine. Dr. Park’s research is supported by federal grants (including R01) and foundation awards such as the Pew Scholar Award. His lab investigates axon regeneration after optic nerve injury and employs advanced techniques like 3D visualization and single-nucleus RNA sequencing. Key contributions include studies on PTEN/SOCS3 signaling pathways and their role in promoting axon regeneration. Grants: R01 (3D Visualization of Retinal Axon Regeneration), multiple R21 grants, Department of Defense funding. Awards: Pew Biomedical Trust Pew Scholar Award, Karl Kirchgessner Foundation Award. Labs/Teams: Director of the Park Lab at UT Southwestern, collaborating with interdisciplinary teams on optic nerve regeneration and neurodegenerative diseases. His work bridges basic science and translational medicine, aiming to restore vision through regenerative strategies. Current initiatives include exploring gene therapy and cellular repopulation for optic neuropathy.

• Metabolic Disorders
• Diabetes Research
• Obesity Studies
• +۳ مورد دیگر

Silvia Corvera is a Professor of Molecular Medicine and holds the Endowed Chair in Diabetes Research at the University of Massachusetts Chan Medical School, within the T.H. Chan School of Medicine's Program in Molecular Medicine. She also serves as Director of the MD/PhD (MSTP) program and the Clinical Translational Research Pathway. Her academic journey includes an MD and MSc in Molecular Biology from the Universidad Nacional Autonoma de Mexico, followed by postdoctoral studies in the U.S. and faculty roles at the University of Pennsylvania and UMass Chan. Her research focuses on understanding cellular and molecular mechanisms underlying metabolic diseases such as type-2 diabetes, non-alcoholic fatty liver disease (NASH), and hypertension. Key areas include adipose tissue dynamics—specifically adipocyte expansion, brite/beige adipocyte function, and adipose organoid development. Collaborations with clinical partners in surgery and obstetrics-gynecology enhance translational research into metabolic disease associations with adipose distribution patterns. Dr. Corvera’s laboratory explores adipose tissue heterogeneity, including its role in energy homeostasis and therapeutic potential. Current projects involve analyzing adipose cell populations via single-cell RNAseq and investigating how genetic factors influence adipose patterning. Her work bridges basic science and clinical applications, addressing obesity-related pathologies and regenerative medicine opportunities. Notable contributions include defining adipose tissue angiogenesis in obesity, generating functional human adipose tissue in vivo, and elucidating mechanisms of adipocyte progenitor differentiation. Her lab actively engages trainees in rotation projects focused on adipocyte biology, cell signaling, and metabolic pathways. Lab activities emphasize interdisciplinary approaches, combining molecular biology, stem cell technology, and systems biology to advance treatments for metabolic disorders. Ongoing efforts investigate adipose-derived cell therapies, CRISPR-enhanced adipocyte browning, and the role of long noncoding RNAs in thermogenesis regulation.

Jonathan K Wattsمشاهده پروفایل

استاد

• Oligonucleotide Therapeutics
• Genome Editing
• Neurodegenerative Diseases
• +۳ مورد دیگر

Jonathan K Watts is a Professor at the RNA Therapeutics Institute and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School. He specializes in optimizing oligonucleotide therapeutics for brain and lung applications and advancing genome editing technologies for clinical use. His work has contributed to multiple oligonucleotide drugs in ALS trials. Key honors include the 2013 Oligonucleotide Therapeutics Society Young Investigator Award and the 2015 Vice-Chancellor’s Teaching Award. Education: PhD in Chemistry (2008), McGill University BSc in Chemistry (2001), Dalhousie University Research Interests: Focuses on developing oligonucleotide-based therapies targeting neurodegenerative diseases and enhancing genome editing precision. His lab explores drug delivery systems, RNA biology, and clinical translation of nucleic acid technologies. Publications: Over 75 papers with 5,000+ citations, emphasizing advancements in antisense oligonucleotides and CRISPR-based therapies. Recent work addresses CNS drug delivery and prime editing optimization. Awards: 2018 Angel Award for ALS Research 2015 Teaching Excellence Award Multiple fellowships and prizes for academic achievement Lab & Collaborations: Leads the Watts Lab, collaborating on projects like the N=1 Collaborative for personalized nucleic acid therapies. Mentors PhD students and postdocs in oligonucleotide design and genome editing.

• Computational Biology
• RNA Epigenetics
• Precision Medicine
• +۵ مورد دیگر

Chan Zhou is an Assistant Professor in the Department of Population and Quantitative Health Sciences at UMass Chan Medical School, with cross-appointments in the T.H. Chan School of Medicine and Morningside Graduate School of Biomedical Sciences. He leads a research lab focused on decoding RNA modifications and noncoding RNAs using computational methods, AI-driven algorithms, and scalable sequencing pipelines to advance precision diagnostics. Education: PhD in Bioinformatics, Zhejiang University Postdoctoral training in RNA epigenomics at Harvard Medical School Visiting PhD student at University of Georgia and Fudan University Research: Dr. Zhou's work integrates machine learning with multi-omics data to identify RNA-based disease biomarkers. Key areas include: single-cell RNA-seq analysis, circular RNA profiling, lncRNA function, and therapeutic target prediction for conditions like liver fibrosis and cancer. The lab emphasizes translational discovery through collaborations with biologists and clinicians. Publication Trends: His recent articles (2016-2025) demonstrate a strong focus on RNA epigenetics, computational tool development (e.g., BAMBI, Flnc), and applications in liver disease and oncology. Machine learning approaches are consistently applied to biomarker discovery, with emerging themes in AI-driven diagnostics and multi-omics integration. Lab & Team: Current members include postdoc Zixiu Li, graduate students Peng Zhou and Euijin Kwon, and clinical fellow TienChan Hsieh. The lab actively recruits postdoctoral researchers for projects in single-cell/long-read sequencing analysis.

• Cancer Cell Metastasis
• Tumor Microenvironment
• Focal Adhesion Signaling
• +۴ مورد دیگر

Vasiliki Gkretsi is an Associate Professor at the School of Sciences, European University Cyprus, Department of Life Sciences. She holds a Ph.D. in Cellular and Molecular Pathology from the University of Pittsburgh (2006) and a Diploma in Biology from the National and Kapodistrian University of Athens (2001). Her research focuses on cancer metastasis mechanisms, particularly the role of focal adhesion proteins like ILK, RSU-1, and GDF-15 in tumor progression. She has held academic roles including Assistant Professor (2017–2020) and Senior Scientist (2015–2017) at the University of Cyprus and University of Thessaly’s biomedical research institutes. Her work integrates bioengineering approaches with molecular biology to study tumor microenvironment dynamics, cell adhesion signaling, and metastatic processes. Key contributions include identifying RSU-1 as a dual-function regulator in breast and glioma cancers and exploring GDF-15’s role in metastasis. She has led projects funded by the European Society for the Study of the Liver (EASL Sheila Sherlock Fellowship) and the Research Promotion Foundation. Education: Ph.D., Cellular and Molecular Pathology, University of Pittsburgh (2006) Diploma in Biology, National and Kapodistrian University of Athens (2001) Awards: EASL Sheila Sherlock Fellowship (2012–2014) Stephen L. Phillips Scientific Achievement Award (2005) Roles: Special Issue Editor, International Journal of Molecular Sciences and Life Member of Bioethics Evaluation Committee for Biomedical Research Her research spans over 45 peer-reviewed articles and has been cited over 1,600 times (Google Scholar). She holds a provisional U.S. patent for anti-inflammatory methods targeting the actin cytoskeleton.

• Immunology
• Inflammasome Biology
• Toll-like Receptors
• +۳ مورد دیگر

Brian Monks is an Instructor in the Department of Medicine at UMass Chan Medical School, affiliated with the T.H. Chan School of Medicine. He holds a BS and MS in Microbiology from the University of Massachusetts Amherst. His research focuses on innate immunity, particularly inflammasome biology and Toll-like receptor signaling, with contributions to understanding inflammation mechanisms and microbial pathogenesis. Monks has collaborated extensively with experts like Dr. Golenbock and Dr. Latz on projects involving NLRP3 inflammasome inhibitors, ASC speck formation, and TLR4 signaling pathways. Notable work includes studies on CRID3 inhibitors and fluorescent reporter systems for inflammasome activity. His publications span Science , Nature Immunology , and Journal of Immunology , addressing topics from amyloid-β immunology to malaria-induced innate responses.

• Biopharmaceutical Engineering
• CHO Cell Biology
• Single-cell Transcriptomics
• +۶ مورد دیگر

Dr. Colin Clarke is an Associate Professor at University College Dublin's School of Chemical and Bioprocess Engineering. His research focuses on advancing biopharmaceutical manufacturing processes through innovative approaches in cell line development, single-cell analysis, and bioprocess optimization. He has established himself as a leading researcher in CHO cell biology and biopharmaceutical production systems. Dr. Clarke received his educational training at prestigious institutions: BSc from Waterford Institute of Technology MSc from Cranfield University, Bedford, UK PhD from Cranfield University, Bedford, UK Dr. Clarke's research program centers on understanding and improving biopharmaceutical production systems. His work spans multiple interconnected areas including CHO cell line development and characterization, mitochondrial DNA analysis, single-cell transcriptomics of production cell lines, and advanced bioprocess monitoring. A significant portion of his research focuses on understanding heterogeneity within production cell populations and how this impacts product quality and yield. His lab has developed innovative approaches for single-cell mitochondrial DNA sequencing and has made important contributions to understanding microprotein impurities in therapeutic antibodies. Dr. Clarke also investigates CAR T-cell production systems, focusing on improving transduction efficiency through modulation of cellular pathways. Analysis of Dr. Clarke's recent publications reveals a strong focus on single-cell technologies applied to biopharmaceutical production systems. His work spans both mammalian (CHO) and insect cell platforms, with particular emphasis on understanding cellular heterogeneity and its impact on product quality. A notable trend is the application of advanced sequencing technologies (RNA-seq, scRNA-seq, Ribo-seq) to uncover previously hidden aspects of cell biology relevant to bioproduction. His research bridges fundamental cell biology with practical bioprocess applications, consistently aiming to translate basic discoveries into improved manufacturing processes. Dr. Clarke actively supervises PhD students as a Thesis Supervisor and contributes to undergraduate and graduate education at University College Dublin. His teaching portfolio includes courses on biopharmaceutical engineering projects, engineering computing, bioprocess scale-up, facility design, and data science applications in biopharmaceutical manufacturing. He has consistently taught these courses since 2020, demonstrating his commitment to developing the next generation of biopharmaceutical engineers.

• Language Acquisition
• Developmental Psychology
• Psycholinguistics
• +۴ مورد دیگر

Alex de Carvalho is a Postdoctoral Researcher at the Laboratoire de Sciences Cognitives et Psycholinguistique (École Normale Supérieure - Paris). His research focuses on language acquisition and development , particularly how children use phrasal prosody and function words to infer syntax and word meaning. He employs eye-tracking , EEG , and behavioral methods to study young children's language comprehension and production. PhD in Cognitive Sciences, École Normale Supérieure - Paris (2017) MA in Cognitive Sciences, École Normale Supérieure - Paris (2014) BA in Linguistics/Education, Federal University of Rio de Janeiro (2011) His work demonstrates that preschoolers and infants use prosodic cues to resolve syntactic ambiguity, linking this to word learning . He has supervised numerous graduate and undergraduate students, including Axel Barrault and Monica Barbir. Collaborators include John Trueswell (University of Pennsylvania) and Jeff Lidz (University of Maryland). Post-Doctoral Grant, Fyssen Fondation (2018-2020) Society for Language Development Student Award (2015) Paula Menyuk Travel Award (multiple years) GDR Neuroscience of Development Travel Award He co-founded the DEC-Life association and managed partnerships with Paris preschools for child experiments. His teaching includes courses on language acquisition and human experimentation at École Normale Supérieure and Université Paris Descartes.

• Pulmonary Fibrosis
• Lung Cancer
• Immunology
• +۳ مورد دیگر

Qin Li, MD, is an Associate Research Scientist in the Department of Pathology at Yale School of Medicine. She holds an MD from Sun Yat Sen University (2012) and specializes in translational research focusing on pulmonary fibrosis, lung cancer biology, and immune mechanisms in infectious diseases. Her work integrates genomic approaches with clinical insights to identify novel therapeutic targets and biomarkers. Dr. Li’s research includes developing transcriptional models of fibrosis progression, exploring RNA networks in lung cancer, and investigating nanoparticle-based therapies for cancer. Notable contributions include defining pyroptosis-related gene signatures in lung adenocarcinoma and characterizing the role of long noncoding RNA TINCR in airway differentiation. She collaborates with teams at the Katz Lab and has co-authored over 20 peer-reviewed publications. Her recent studies span immunological aspects of SARS-CoV-2 and parasitic infections, reflecting interdisciplinary strengths. Dr. Li was recognized for coordinating PPE donations during the pandemic, demonstrating commitment to clinical and community health.

• Cardiovascular Disease
• Sleep Medicine
• Pulmonary Fibrosis
• +۳ مورد دیگر

Dr. Li Qin is an Associate Research Scientist in Medicine (Cardiology) at Yale School of Medicine, with a PhD from the University of Pittsburgh (2006). Her research focuses on cardiovascular disease risk factors, sleep-related disorders, and pulmonary fibrosis. Key collaborations include work with Drs. Andrey Zinchuk, Brian Koo, and Henry Yaggi on sleep apnea and cardiovascular outcomes. She contributes to the Center for Outcomes Research & Evaluation (CORE) and explores genetic and molecular mechanisms underlying fibrotic diseases. Recent studies investigate pyroptosis-related gene signatures in lung cancer and Src kinase inhibitors for pulmonary fibrosis treatment.

• Cardiovascular Disease
• Non-coding RNAs
• Molecular Biology
• +۴ مورد دیگر

Li Peifeng is a distinguished Professor and Dean at the Institute of Translational Medicine, College of Medicine, Qingdao University, China. He also serves as Director of the Key Laboratory of Nucleic Acid Biology in Cardiovascular Disease (Shandong) and the International Research Centre for Non-coding RNAs and Translational Medicine (Qingdao). His academic career includes roles as Distinguished Professor at the Chinese Academy of Sciences (2006–2013) and a Medical Researcher at the Max-Delbrück-Center for Molecular Medicine in Berlin (1995–2005). Li Peifeng holds an MD and PhD from the Chinese Academy of Medical Science (1990–1993). His research focuses on cardiovascular biology, non-coding RNAs, and molecular mechanisms underlying myocardial infarction, heart failure, and apoptosis. He has led groundbreaking studies on miRNA regulation in cardiac pathologies and oxidative stress responses. Notable awards include the World’s Top 2% Scientists (2020), Highly Cited Chinese Researchers (2020), and multiple national and provincial accolades. He is an editorial board member for journals like Molecular Biotechnology and Circulation Research , and has reviewed grants for institutions including the European Research Council and the American Heart Association. Awards: Taishan Scholar (2018), Leading Innovative Scientist (2018), Tip-top Talent (2017). Leadership Roles: Organized major conferences, including the Annual Conference on Cell Biology (2018) and International Cardiology Conferences (2014–2015). Key Labs: Directs research centers focused on nucleic acid biology and non-coding RNAs in cardiovascular disease.

Joachim Lingnerمشاهده پروفایل

استاد

• Telomeres
• Telomerase
• Long noncoding RNA
• +۶ مورد دیگر

Joachim Lingner is a Full Professor at the Ecole Polytechnique Fédérale de Lausanne (EPFL) since 2009. He previously held positions as Associate Professor (2005–2008), Senior group leader (2002), and Junior group leader (1997–2001) at EPFL and ISREC, Switzerland. He completed his PhD at the Biozentrum of the University of Basel (1989–1992) and postdoctoral work at HHMI, University of Colorado at Boulder (1993–1997). Research Focus: Telomeres, telomerase, genome stability, DNA repair, oxidative stress, RNA biology, and aging. Key Discoveries: Discovery of the catalytic subunit of telomerase (1993–1997), identification of TERRA (telomeric long noncoding RNA), and mechanisms of telomerase regulation. Technologies Developed: Telomeric chromatin analysis protocols to study telomere protein composition and dynamics. Scientific Awards & Honors: ERC Advanced Investigator Grant (2008) EMBO Member (2005) Friedrich Miescher Prize (2002) START-fellowship (1997) Postdoctoral Fellowship SNF (1995) EMBO Long-Term Postdoctoral Fellowship (1993)

• Genetic Disorders
• Pediatrics
• Medical Genetics
• +۳ مورد دیگر

Dr. Sarah Sandaradura is a Clinical Associate Lecturer in Paediatrics & Child Health at the Children's Hospital, Westmead. Her research focuses on genetic and genomic approaches to diagnosing rare pediatric diseases, particularly mitochondrial disorders, neuromuscular conditions, and congenital anomalies. She specializes in ultra-rapid genomic sequencing for critically ill infants and children, contributing to national healthcare systems' implementation of these technologies. Her work bridges clinical practice and research, emphasizing diagnostic efficiency and workforce training in genomic medicine. Key research interests include: Ultrarapid genomic testing protocols in acute pediatric care Multi-omics integration for rare disease diagnosis Genetic variants associated with neurofibromatosis and congenital myopathies Health economics of genomic diagnostic pipelines Recent publications highlight advancements in: Boosting neuromuscular diagnosis rates through RNA sequencing Expanding allelic heterogeneity understanding in autosomal recessive ataxias National scaling of critical care genomic testing Genotype-phenotype correlations in NF1 variants She co-led the 2022 RNA-4RD grant project developing clinical RNA diagnostics pipelines. Her work emphasizes translating genomic discoveries into actionable clinical strategies for pediatric patients.

• Nephrology
• Immunology
• Chronic Kidney Disease
• +۳ مورد دیگر

Associate Professor Yiping Wang is affiliated with the Westmead Clinical School and the Westmead Institute for Medical Research at the University of Sydney. Their research focuses on immunological mechanisms in renal injury, autoimmune diseases, and molecular pathways regulating cellular senescence. They hold a dual role as Senior Research Fellow and Associate Professor, emphasizing translational research in kidney diseases. Key research grants include investigations into DNA damage signaling in polycystic kidney disease (2019) and the role of dendritic cells in chronic kidney disease treatment (2017), both funded by NHMRC Project Grants. Their work bridges basic science and clinical applications, particularly in biomarker discovery and repurposing therapeutic agents. Research interests span nephrology, immunology, and molecular biology, with recent studies exploring long noncoding RNAs as rheumatoid arthritis biomarkers and JNK pathway-driven endothelial senescence in chronic inflammation. Collaborations include teams at the Westmead Institute and international co-authors across immunology and nephrology disciplines.

David J. Waxmanمشاهده پروفایل

استاد

• Genomic and Epigenetic Mechanisms
• Molecular Endocrinology
• Cancer Therapy
• +۴ مورد دیگر

David J. Waxman is a Professor of Biology, Medicine, and Biomedical Engineering at Boston University. He holds a PhD from Harvard University and leads a research program focusing on genomic, epigenetic, and hormonal mechanisms regulating liver gene expression, environmental chemical toxicity, and cancer immunotherapy. His work combines advanced genomic technologies like scRNA-seq and ChIP-seq with mouse models to study sex-differential gene expression, environmental toxin impacts, and anti-tumor immune responses. Research Interests: Genomic/epigenetic control of liver gene expression Hormonal regulation via growth hormone (GH) and nuclear receptors Environmental chemicals and developmental toxicity Immunogenic chemotherapy strategies Non-coding RNA roles in liver physiology Recent Work Trends: Over 150 publications highlight his focus on sex-biased gene networks, metronomic chemotherapy’s immune activation, and environmental chemical-induced epigenetic reprogramming. Key techniques include CRISPR-based epigenetic editing and single-cell transcriptomics. Labs/Teams: Directs a multi-disciplinary lab integrating molecular biology, bioinformatics, and preclinical oncology studies. Collaborates with institutions like Harvard and MIT on translational projects.