Chan Zhou

Chan Zhou is an Assistant Professor in the Department of Population and Quantitative Health Sciences at UMass Chan Medical School, with cross-appointments in the T.H. Chan School of Medicine and Morningside Graduate School of Biomedical Sciences. He leads a research lab focused on decoding RNA modifications and noncoding RNAs using computational methods, AI-driven algorithms, and scalable sequencing pipelines to advance precision diagnostics.

Education:

• PhD in Bioinformatics, Zhejiang University
• Postdoctoral training in RNA epigenomics at Harvard Medical School
• Visiting PhD student at University of Georgia and Fudan University

Research: Dr. Zhou's work integrates machine learning with multi-omics data to identify RNA-based disease biomarkers. Key areas include: single-cell RNA-seq analysis, circular RNA profiling, lncRNA function, and therapeutic target prediction for conditions like liver fibrosis and cancer. The lab emphasizes translational discovery through collaborations with biologists and clinicians.

Publication Trends: His recent articles (2016-2025) demonstrate a strong focus on RNA epigenetics, computational tool development (e.g., BAMBI, Flnc), and applications in liver disease and oncology. Machine learning approaches are consistently applied to biomarker discovery, with emerging themes in AI-driven diagnostics and multi-omics integration.

Lab & Team: Current members include postdoc Zixiu Li, graduate students Peng Zhou and Euijin Kwon, and clinical fellow TienChan Hsieh. The lab actively recruits postdoctoral researchers for projects in single-cell/long-read sequencing analysis.