Zhou Sha

Zhou Sha is a Research Fellow in the Department of Chemistry at Pennsylvania State University, affiliated with the Benkovic Group. Their research spans structural biology, drug discovery, and computational methods in molecular science. Located at 413 Wartik Lab, Zhou's work addresses challenges in RNA structure prediction, protein interactions, and therapeutic development for diseases like cancer and retinal disorders.

Research interests include leveraging quantum machine learning for drug discovery, optimizing optogenetic engineering techniques, and investigating protein toxicities in neurodegenerative contexts. Recent studies focus on REDD1 protein allostery in retinal diseases and SOD1 trimers' role in motor neuron damage. Collaborations emphasize interdisciplinary approaches, combining bioinformatics with experimental methodologies like finite element modeling for wound closure studies.

Publications highlight advancements in RNA 3D structure prediction via Euclidean neural networks, design of tumor-targeting immune therapies, and meta-analyses of microRNA biomarkers. While no formal student advisement or awards are cited, Zhou's work contributes significantly to translational biomedical research through the Benkovic Group's platforms.