جست‌وجوی استاد و پژوهشگر

• Nutrition
• Diabetes Research
• Endocrine Disruption
• +۳ مورد دیگر

Magdalena Alonso serves as Associate Professor in the Department of Applied Biology at Miguel Hernández University of Elche and holds the position of Deputy Director at the Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDIBE). Her academic responsibilities include coordinating and teaching Human Nutrition for the Bachelor's in Food Science and Technology, laboratory instruction for Nutrition in Biotechnology, and Cellular and Molecular Aspects of Diabetes and Obesity for the Master's in Biotechnology and Bioengineering, while also directing the Doctorate in Health Biotechnology program. Her research centers on molecular mechanisms of pancreatic cell dysfunction in diabetes and obesity, with particular emphasis on endocrine disruptors like bisphenol A. She investigates how environmental chemicals alter insulin/glucagon secretion, beta-cell proliferation, and glucose homeostasis through estrogen receptor signaling, ion channel modulation, and epigenetic pathways. Current work employs multi-omics approaches to characterize metabolic disruptions from pollutants. Analysis of her 2022-2025 publications reveals consistent focus on pancreatic alpha/beta cell biology, with recurring themes including gestational diabetes mechanisms, bile acid signaling in glucagon regulation, and multi-omics characterization of pollutant effects. Key methodologies involve in vitro cell models, transgenic mice, and integrated omics analyses to dissect molecular pathways. Scientific Awards: No awards documented in source materials As Doctorate in Health Biotechnology Program Coordinator, she oversees graduate training while conducting research within the Diabetes Research Unit. Her laboratory work at IDIBE focuses on screening metabolism-disrupting chemicals using pancreatic cell models, with future directions targeting improved endocrine disruptor detection methods and therapeutic interventions for chemical-induced diabetes. Collaborative projects emphasize healthcare biotechnology applications for metabolic disorders.

• Connexins
• Gap Junctions
• Intercellular Junctions
• +۱۱ مورد دیگر

Dr. Eric Beyer is a Professor of Pediatrics at the University of Chicago, serving as Vice Chairman for Academic Affairs in the Department of Pediatrics and specializing in the Section of Hematology/Oncology and Stem Cell Transplantation. As a physician scientist, Dr. Beyer practices pediatric hematology/oncology while maintaining an active research laboratory focused on intercellular communication through gap junctions. Dr. Beyer received his AB in Biological Sciences from the University of Chicago, followed by a PhD in Physiology and Pharmacology and an MD from UCSD. His clinical training includes an internship and residency in Pediatrics at Children's Hospital, Boston, and a fellowship in Pediatric Hematology/Oncology at Children's Hospital and Dana Farber Cancer Center, Boston. Dr. Beyer's research spans nearly three decades, investigating the role of connexins and gap junctions in various physiological processes and disease states. His laboratory has identified and cloned subunit proteins, characterized structure-function relationships, and determined pathways of biosynthesis and degradation. Key research areas include: Connexins in eye lens and cataract formation Cardiac connexins in normal conduction and arrhythmia pathogenesis Extracellular vesicles in vascular pathologies of sickle cell disease Intercellular communication mechanisms in health and disease Analysis of Dr. Beyer's recent publications reveals a strong focus on the molecular mechanisms underlying cataract formation through connexin mutations, with particular emphasis on biomineralization processes and calcium deposition. His work also demonstrates a significant shift toward translational research on sickle cell disease, particularly examining how circulating extracellular vesicles contribute to vaso-occlusive crises and acute chest syndrome. This dual focus on basic molecular mechanisms and clinical applications represents the hallmark of his translational research approach. Dr. Beyer has received numerous prestigious honors including membership in the American Society for Clinical Investigation, Fellowship in the Society for Pediatric Research, and Fellowships from the American Heart Association and the Association for Research in Vision and Ophthalmology. As a mentor, Dr. Beyer has guided numerous students and post-doctoral fellows through his laboratory. His current research is supported by multiple NIH grants, including R01EY030914 for 'Geobiology of Cataracts' (2020-2024) and KL2TR002387 for 'Institutional Career Development Core' (2017-2027), where he serves as Principal Investigator. His extensive grant history demonstrates continuous funding since 1990, reflecting the significance and impact of his research. Dr. Beyer's laboratory maintains a strong focus on the structural and functional aspects of connexins in multiple organ systems, with particular expertise in lens biology and cardiovascular function. His team combines molecular, cellular, and physiological approaches to investigate both basic mechanisms of intercellular communication and their implications for human disease.

Axel Concepcionمشاهده پروفایل

استادیار

• Membrane Proteins
• Ion Channels
• Immune Cell Regulation
• +۴ مورد دیگر

Axel Concepcion is an Assistant Professor at the University of Chicago's Department of Biochemistry and Molecular Biology. His research focuses on ion channels and membrane proteins in immune cell regulation. Education: BSc in Chemical Technology (University of Panama), MSc in Cell & Molecular Biology (University of Navarra), PhD in Cell & Molecular Biology and Immunology (University of Navarra), Postdoc in Immunology (NYU School of Medicine) Awards: Young Investigator Award (2024), Neubauer Family Assistant Professorship (2022), Bernard B. Levine Fellowship (2018), Alfonso Martin Escudero Fellowship (2015), Torres Quevedo Award (2010), Excellence Scholarship (2008), Short-term Fellowships (2007, 2005) Research Interests: Dr. Concepcion's lab investigates how ion channels regulate immune cell function through functional genomics, systems immunology, and electrophysiology. Key areas include: Swelling-activated ion channels in immunity Calcium signaling networks Membrane protein regulation Translational immunotherapy Scientific Contributions: His work spans multiple disciplines including: Calcium signaling in T cells Volume-regulated anion channels Exocrine gland physiology Autoimmune disease mechanisms Dr. Concepcion has received significant grant funding including NIH R35GM155189 (2024-2029) for studying immune cell regulation by ion channels.

• Neuroscience
• Neurophysiology
• Synaptic Plasticity
• +۵ مورد دیگر

Fuwen Zhou , Assistant Professor at the University of Maryland School of Medicine , focuses on Neurobiology research. His work investigates neural function and behavior in brain regions like the olfactory bulb, cortex, and basal ganglia, using techniques such as patch clamp electrophysiology , optogenetics , and chemogenetics in healthy and disease models (Alzheimer's, Parkinson's, epilepsy). Education : Bachelor of Medicine (Dental Medicine), Central South University Xiang-Ya School of Medicine, China Master of Medicine (Pharmacology), Central South University Xiang-Ya School of Medicine, China Dr. rer. nat. (Cell Biology), University of Rostock, Germany His research spans synaptic plasticity , neural circuits , and neurodegenerative disease mechanisms , as evidenced by publications on HCN and TRP channels , excitation-inhibition balance , and animal models . Recent studies highlight olfactory bulb dynamics , cortical circuit dysfunction , and neurotransmitter modulation in disease contexts. Articles from 2024-2009 reflect consistent contributions to neurophysiology , synaptic plasticity , and neural network analysis .

Poonam Thakurمشاهده پروفایل

استادیار

• Neurodegenerative Diseases
• Neuroscience
• Molecular Biology
• +۶ مورد دیگر

Poonam Thakur is an Assistant Professor at the School of Biology , Indian Institute of Science Education and Research Thiruvananthapuram. Her research focuses on Parkinson’s disease (PD), specifically the molecular mechanisms of neurodegeneration, development of mouse models, and neuroprotective strategies. PhD in Neuroscience from Panjab University (2014) Postdoctoral work at Lund University (Sweden) and Goethe University (Germany) Wellcome Trust/DBT India Alliance Early Career Fellow (2019-2024) Research Emphasis : Developing accurate PD models to study pathogenesis Investigating lipid alterations, post-translational modifications, and neuroinflammation in PD progression Expanding into machine learning and AI for data analysis Key Awards : Junior Scientist Award (International Parkinson & Movement Disorder Society, 2016) Multiple travel awards for international conferences (Japan, Canada, Denmark, Switzerland, etc.) Funding Sources : Parkinson's Foundation USA DBT-Wellcome Trust India Alliance Cure Parkinson’s Trust UK SERB and IISER intramural funds

Amy Arnstenمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Cognitive Science
• +۷ مورد دیگر

Amy Arnsten is the Albert E. Kent Professor of Neuroscience and Professor of Psychology at Yale School of Medicine, with secondary appointments in the Child Study Center and Department of Psychiatry. She is a member of the Kavli Institute of Neuroscience at Yale University and the National Academy of Medicine. Primary Appointment: Department of Neuroscience, Yale School of Medicine Secondary Appointments: Child Study Center, Department of Psychology, Department of Psychiatry Organizational Affiliations: Alzheimer's Disease Research Center, Center for Brain & Mind Health, Wu Tsai Institute, Yale Center for Research on Aging Dr. Arnsten's research focuses on molecular regulation of prefrontal cortical circuits, particularly how neuromodulators like norepinephrine and dopamine influence working memory through Dynamic Network Connectivity mechanisms. Her work has revealed how stress, aging, and genetic mutations disrupt these pathways, leading to cognitive disorders in Alzheimer's disease, schizophrenia, and ADHD. She pioneered the development of guanfacine (Intuniv™) for ADHD treatment based on her molecular insights. Her recent publications (2024-2025) demonstrate a strong focus on Alzheimer's disease mechanisms, particularly tau pathology propagation in primate models, calcium dysregulation in aging neurons, and translational biomarker development. Key themes include vulnerable prefrontal neuron populations, synaptic density measurement, and molecular targets for cognitive enhancement. Member, National Academy of Medicine (2017) Goldman-Rakic Prize for Outstanding Achievement in Cognitive Neuroscience (2015) Dr. Arnsten leads the Arnsten Lab, which employs multi-disciplinary approaches including primate neuroanatomy, molecular signaling analysis, and behavioral testing. Her research has direct clinical applications, with discoveries translating to treatments for ADHD, PTSD, and cognitive deficits in aging. Current work focuses on preventing early-stage tau pathology and developing novel cognitive enhancers targeting glutamate and calcium signaling pathways.

Christian Hanselمشاهده پروفایل

استاد

• Synaptic Plasticity
• Intrinsic Plasticity
• Cerebellum
• +۴ مورد دیگر

Christian Hansel is a Professor in the Department of Neurobiology at the University of Chicago. His research focuses on synaptic and intrinsic plasticity mechanisms in the cerebellum, particularly their roles in learning, memory, and neurological disorders such as autism spectrum disorder (ASD). The lab employs Patch-clamp recordings Confocal calcium imaging Immunohistochemistry Behavioral testing to investigate these processes. Education: Diploma in Zoology from University of Zurich, Switzerland Ph.D. in Neurobiology from Max-Planck-Institute for Brain Research, Germany Postdoc in Neurobiology at Johns Hopkins University Research interests center on bidirectional synaptic plasticity (long-term potentiation and depression) and intrinsic excitability changes in Purkinje cells, with a focus on Calcium-dependent signaling Climbing fiber-Purkinje cell interactions Alcohol's effects on cerebellar function Autism-related synaptopathies Neuronal ensemble dynamics Motor learning mechanisms The 15 most recent publications highlight his work on cerebellar plasticity, autism models, and ion channel modulation. These studies appear in journals such as Elife , Nature Communications , and Neuron , spanning fields like Neuroscience, Cell Biology, and Neurology. Hansel serves as Principal Investigator on NIH grants including R01NS062771 (active through 2024) and R21NS140563 (2025-2027), exploring topics from synaptic gain control to climbing fiber signaling outside the cerebellum. His lab has contributed significantly to understanding how SK2 channels regulate neuronal excitability and how cerebellar dysfunction contributes to ASD.

• Transcriptomics
• Epigenomics
• Bioinformatics
• +۶ مورد دیگر

Claire Wilson is a Lecturer in Pharmacology at the University of Chester's Faculty of Health, Medicine and Society. Her research integrates transcriptomic and epigenomic approaches with bioinformatics tools, focusing on DNA methylation, long non-coding RNAs, and calcium signaling in cardiovascular and cancer contexts. She collaborates with the University of Liverpool and University of Birmingham on oncogene-induced replication stress, and maintains cardiovascular partnerships with the University of Manchester. PhD in Molecular Biology (University of Manchester, 2014-2017) MRes in Molecular Biology (University of Manchester, 2013-2014) BSc in Biological Sciences (University of Liverpool, 2010-2013) Her research portfolio spans two major domains: cardiovascular epigenetics (investigating AV/Sinus node dysfunction through proteomic/transcriptomic analysis) and cancer epigenetics (exploring lncRNA regulation of DNA methylation and the 8q24.21 cancer locus). Recent publications demonstrate expertise in bioinformatics integration , mouse modeling , and calcium homeostasis mechanisms. Articles cluster around: Calcium handling in cardiac arrhythmias (PMCA1, HCN channels) Epigenetic regulation of cancer (lncRNAs, DNA methylation) Inflammatory pathways in heart failure ERM phosphorylation and vascular calcification Replication stress in oncology Translational cardiovascular pharmacology

Timothy Copeمشاهده پروفایل

استاد

• Neuroscience
• Regenerative Medicine
• Sensorimotor Integration
• +۳ مورد دیگر

Dr. Timothy Cope is a Professor at Georgia Institute of Technology's School of Biological Sciences within the College of Sciences . His research focuses on sensorimotor integration in the mammalian spinal cord , particularly examining neural signaling in motoneurons and somatosensory neurons after peripheral nerve injuries. He also directs the PhD Program in Neuroscience and Neurotechnology. Research Interests: Spinal cord neural circuits and movement control Peripheral nerve injury regeneration Chemotherapy-induced sensory neuropathy Mechanosensory encoding mechanisms Synaptic plasticity in motor disorders Education: PhD - Duke University BS and MS - UCLA Key Research Trends: Recent publications emphasize computational modeling of muscle spindle encoding, cancer-chemotherapy interaction effects on sensory neurons, and microglia-mediated synaptic plasticity following peripheral injuries. His work bridges neurophysiology , biomechanics , and clinical oncology to address movement disorders.

Agnes Gruart Massoمشاهده پروفایل

استاد

• Associative Learning
• Hippocampal Long-Term Potentiation (LTP)
• Neuroprotection in Ischemia
• +۷ مورد دیگر

Agnes Gruart Masso is a Professor at Universidad Pablo de Olavide , where she works in the Department of Physiology, Anatomy and Cell Biology . Her academic career spans over three decades since her 1994 PhD thesis on classical conditioning of the corneal reflex under Dr. José María Delgado García. Key research areas: Associative learning mechanisms , Hippocampal synaptic plasticity , Neuroprotection in ischemia , and Cerebellar nuclei functions Current affiliations: Neuroscience Laboratory , PAIDI Biology and Biotechnology Her experimental work with alert behaving animals has revealed critical insights into synaptic plasticity through chronic in vivo models of Alzheimer's disease , Huntington's disease , and stroke . She pioneered techniques combining magnetic search-coil recordings with pharmacological interventions to study motor learning and cognitive processes . Recent publications demonstrate her focus on neuroinflammatory mechanisms (2024 study on IKKβ deletion), metabotropic receptor activation (2023 mGluR4 work), and neurodegenerative disease models (2023 Huntington's research). Her 2025 studies on presenilin inactivation and oligodendrocyte regulation continue expanding understanding of synaptic dysfunction in disease contexts.

Birgit Karner-Högerمشاهده پروفایل

استادیار

• Molecular Pharmacology
• Ion Channels
• Immune Homeostasis
• +۳ مورد دیگر

Dr. Birgit Karner-Höger is a University Assistant at the Institute of Pharmacology within the Faculty of Medicine at Johannes Kepler University Linz, Austria. She leads research in the Molecular Pharmacology group under the supervision of Professor Susanna Zierler. Her work focuses on understanding molecular mechanisms of ion channels, particularly TRPM7, in immune homeostasis and disease. Dr. Karner-Höger received her PhD in Biology from EMBL European Molecular Biology Laboratory and University of Heidelberg, Germany in 2016, and her MSc in Biochemistry from Graz University of Technology in 2012. Prior to her current position, she worked as a Scientist at Baxalta Innovations GmbH (Takeda Pharmaceutical) and as a Postdoctoral Researcher at the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, CeMM Research Center, and St. Anna Children's Cancer Research Institute in Vienna. Her research interests span molecular pharmacology of ion channels, particularly focusing on TRPM7's dual role as a signaling protein and magnesium ion-conducting channel in immune cells. She investigates TRPM7's role in immune homeostasis, human leukemias, and cellular metabolism using molecular biology, immunology techniques, patch clamp electrophysiology, and Seahorse metabolic flux analysis. Her work aims to identify pharmacological modulators of TRPM7 to understand disease mechanisms and develop potential therapies. Dr. Karner-Höger's publications demonstrate a strong focus on the intersection of ion channel biology and immunology. Her recent work examines TRPM7's kinase domain in human CML cells, its role in macrophage phagosome maturation, and its significance in immune cell function. Her research contributes significantly to understanding how ion channels regulate immune responses and how their dysfunction can lead to disease. She has received several prestigious awards including the Expert Intern Careers Fellowship from the Ludwig Boltzmann Society (2020), Hertha Firnberg Postdoctoral Fellowship from the Austrian Research Fund (2017-2020), DOC Doctoral Fellowship from the Austrian Academy of Sciences (2013-2015), and the KUWI Research Scholarship from Graz University of Technology (2011). Dr. Karner-Höger is an active member of several professional organizations including the Austrian Pharmacological Society (since 2022), Society of General Physiologists (2021), Austrian Society for Allergology and Immunology (since 2023), and the Austrian Biophysical Society (since 2023). Her work bridges basic science and clinical applications, with potential implications for treating immune disorders and cancers.

• Physiology
• Biophysics
• Cardiac Physiology
• +۴ مورد دیگر

Thomas Shannon, DVM, PhD, is an Associate Professor at Rush Medical College within the Department of Physiology & Biophysics at Rush University. His research focuses on calcium signaling in cardiac myocytes, particularly the role of sarcoplasmic reticulum (SR) in excitation-contraction coupling and pathologies like heart failure. He employs biochemical, biophysical, and molecular approaches to study SR calcium regulation and its implications in normal and diseased states. Educational Background : PhD and DVM from University of Missouri Research Interests include: Calcium homeostasis in cardiac cells Ryanodine receptor function and phosphorylation Adrenergic signaling in heart failure Sarcoplasmic reticulum calcium leak Excitation-contraction coupling mechanisms Molecular biophysics of ion transport Publication Trends show a focus on cardiac physiology, calcium signaling, and excitation-contraction coupling from 1994 to 2022, with collaborations with Douglas Bers, Eduardo Rios, and other leading researchers. While no formal scientific awards are listed, his work has been cited extensively in journals like Biophysical Journal and Journal of Molecular and Cellular Cardiology . Collaborations include researchers such as Dirk Gillespie, Eduardo Rios, and Michael Fill. His laboratory at Rush University investigates SR calcium dynamics using electrophysiology and fluorescence detection methods. The full NCBI bibliography and Scopus profile are accessible via institutional links.

Scott K Adneyمشاهده پروفایل

استادیار

• Clinical Epilepsy
• Neurogenetics
• Genetic Determinants of Epilepsy
• +۳ مورد دیگر

Scott K Adney is an Assistant Professor in the Department of Neurology at Northwestern University Feinberg School of Medicine. His clinical and research focus lies in clinical epilepsy , particularly exploring genetic determinants of epilepsy in cases involving developmental delay and ion channel variants. Education: MD and PhD from Virginia Commonwealth University School of Medicine (2015). Training: Intern and Resident in Neurology at McGaw Medical Center of Northwestern University (2016–2021). Certifications: Board-certified in Neurology, Epilepsy, and Critical Care EEG Monitoring. His research emphasizes the intersection of epilepsy , neurogenetics , and ion channel dysfunction , with notable work on SCN2A variants and cortical dysplasia. Recent publications highlight collaborations in neurosurgical case studies and oncology-related neurological complications.

Alicia D Guemez Gamboaمشاهده پروفایل

استادیار

• Neurodevelopmental Disorders
• Autism Spectrum Disorders
• Epilepsy
• +۵ مورد دیگر

Alicia D Guemez Gamboa is an Assistant Professor in the Department of Neuroscience at Northwestern University's Feinberg School of Medicine. She leads the Guemez-Gamboa Lab, which investigates molecular mechanisms of neurodevelopmental disorders using human genetics, induced pluripotent stem cells (iPSCs), CRISPR editing, and organoid models. Her primary affiliations include the Center for Autism and Neurodevelopment, Northwestern University Clinical and Translational Sciences Institute (NUCATS), and Simpson Querrey Institute for Epigenetics. Dr. Guemez Gamboa holds a PhD from Universidad Nacional Autónoma de México (2011) and completed postdoctoral training at UC San Diego (Neurobiology, 2012) and Rockefeller University (Human Genetics and Neuroscience, 2017). Her research focuses on cellular recognition systems governing neural circuit assembly, with emphasis on autism, epilepsy, and rare genetic disorders like PACS1 syndrome. Work combines patient-derived iPSCs, forebrain organoids, and animal models to decode disease mechanisms and develop therapeutic strategies. Key interests include neuronal migration defects, synaptic dysfunction, and the role of protocadherins in brain connectivity. Publications demonstrate consistent focus on neurodevelopmental pathology using advanced disease modeling techniques. Recent work (2023-2025) highlights cerebral organoid applications for studying PACS1/PCDH12 syndromes, neuronal migration deficits, and proteomic alterations. Earlier research (2015-2019) established contributions to pontocerebellar hypoplasia genetics, Zika virus neuropathology, and fatty acid transport mechanisms. Honors include: PACS Syndrome Research Foundation Investigator (2019, 2023) American Epilepsy Society Young Investigator Award (2019) NIH NINDS Mentoring Scholar (2022) Feinberg Outstanding Teacher Award (2020, 2021) She mentors through Northwestern's neuroscience programs and contributes to a $17M NIH grant studying autism/schizophrenia genetics. Lab activities emphasize translating genetic findings into personalized therapeutic approaches for neurodevelopmental conditions.

Michael B. Hoppaمشاهده پروفایل

دانشیار

• Neurobiology
• Ion Channel Function
• Synaptic Transmission
• +۴ مورد دیگر

Michael B. Hoppa is an Associate Professor of Biological Sciences at Dartmouth College and Co-Director of the Integrative Neuroscience Graduate Program. He also holds affiliations with the Molecular and Cellular Biology Graduate Program, the Program in Experimental and Molecular Medicine, and the Institute for Biomolecular Targeting. His research focuses on ion channel function, synaptic transmission, and neurodegenerative disorders using optogenetic and fluorescent microscopy techniques. Education B.A. from Reed College D.Phil. from University of Oxford Research Interests Dr. Hoppa's laboratory investigates how ion channels and their molecular partners regulate electrical signaling in neurons. His team uses human disease-causing mutations as tools to study channelopathies and develops optical techniques for measuring ion channel activity at the nanometer scale within live neurons. Current projects aim to identify therapeutic regulators of synaptic dysfunction in aging and developmental neurological disorders. Publications Trend His recent work emphasizes advancements in glutamate imaging, synaptic vesicle dynamics, and ER calcium signaling, with collaborations spanning molecular neuroscience, neuroengineering, and neurodegenerative disease research. Laboratory The Hoppa Laboratory is located in the Life Sciences Building at Dartmouth, with a focus on optogenetics, quantitative fluorescence microscopy, and molecular biology to study axonal and synaptic ion channels. The lab actively recruits graduate students and postdocs.