Agnes Gruart Masso

Agnes Gruart Masso is a Professor at Universidad Pablo de Olavide, where she works in the Department of Physiology, Anatomy and Cell Biology. Her academic career spans over three decades since her 1994 PhD thesis on classical conditioning of the corneal reflex under Dr. José María Delgado García.

• Key research areas: Associative learning mechanisms, Hippocampal synaptic plasticity, Neuroprotection in ischemia, and Cerebellar nuclei functions
• Current affiliations: Neuroscience Laboratory, PAIDI Biology and Biotechnology

Her experimental work with alert behaving animals has revealed critical insights into synaptic plasticity through chronic in vivo models of Alzheimer's disease, Huntington's disease, and stroke. She pioneered techniques combining magnetic search-coil recordings with pharmacological interventions to study motor learning and cognitive processes.

Recent publications demonstrate her focus on neuroinflammatory mechanisms (2024 study on IKKβ deletion), metabotropic receptor activation (2023 mGluR4 work), and neurodegenerative disease models (2023 Huntington's research). Her 2025 studies on presenilin inactivation and oligodendrocyte regulation continue expanding understanding of synaptic dysfunction in disease contexts.