معرفی
Thomas Shannon, DVM, PhD, is an Associate Professor at Rush Medical College within the Department of Physiology & Biophysics at Rush University. His research focuses on calcium signaling in cardiac myocytes, particularly the role of sarcoplasmic reticulum (SR) in excitation-contraction coupling and pathologies like heart failure. He employs biochemical, biophysical, and molecular approaches to study SR calcium regulation and its implications in normal and diseased states.
- Educational Background: PhD and DVM from University of Missouri
Research Interests include:
- Calcium homeostasis in cardiac cells
- Ryanodine receptor function and phosphorylation
- Adrenergic signaling in heart failure
- Sarcoplasmic reticulum calcium leak
- Excitation-contraction coupling mechanisms
- Molecular biophysics of ion transport
Publication Trends show a focus on cardiac physiology, calcium signaling, and excitation-contraction coupling from 1994 to 2022, with collaborations with Douglas Bers, Eduardo Rios, and other leading researchers. While no formal scientific awards are listed, his work has been cited extensively in journals like Biophysical Journal and Journal of Molecular and Cellular Cardiology.
Collaborations include researchers such as Dirk Gillespie, Eduardo Rios, and Michael Fill. His laboratory at Rush University investigates SR calcium dynamics using electrophysiology and fluorescence detection methods. The full NCBI bibliography and Scopus profile are accessible via institutional links.
