جست‌وجوی استاد و پژوهشگر

Ka Herمشاهده پروفایل

پژوهشگر

• Genomics
• Microbiome Research
• Computational Biology
• +۳ مورد دیگر

Ka Her is a Researcher at the University of California San Francisco (UCSF). Their work focuses on integrating computational methods with genomic and microbiological research to understand complex biological systems. Key areas include chromatin structure analysis, microbiome interactions, and the application of machine learning to genomic data. Ka Her has contributed to advancements in single-cell and multi-omic technologies, particularly in dissecting regulatory elements and their roles in disease contexts such as cancer and inflammatory bowel disease. Their research also explores evolutionary genomics, with studies on human accelerated regions and comparative analyses across species. Publications highlight innovative approaches like CellWalker2 for hierarchical cell-type discovery and MIDAS v3 for microbial gene content estimation. Ka Her’s work frequently bridges basic science and clinical applications, exemplified by studies on fecal microbial transplants and genetic determinants of heart disease. While no formal awards are listed, their extensive publication record reflects significant contributions to computational and experimental genomics.

Eric C. Martensمشاهده پروفایل

استاد

• Microbial Metabolism
• Gut Microbiome
• Inflammatory Bowel Disease
• +۶ مورد دیگر

Eric C. Martens is a Professor of Microbiology and Immunology at the University of Michigan Medical School. His research focuses on the role of human gut microbiota in metabolizing complex carbohydrates and their implications in inflammatory diseases. He leads the Martens Lab and is a Center Member at the Rogel Cancer Center. Education: PhD in Microbiology from the University of Wisconsin (2005); BA in Biology from Washington University (1997). Research interests include microbial carbohydrate metabolism, host-microbe interactions in inflammatory bowel disease (IBD), and microbiome-driven therapeutic strategies. His lab investigates how gut bacteria degrade mucin glycans and dietary fibers, with recent studies on symbiotic species like Bacteroides and Ruminococcus torques . Recent publications highlight mechanisms linking diet, microbiota composition, and disease susceptibility. Key findings include the role of Eubacterium rectale in low-fiber diets and Bacteroides ovatus in mitigating graft-versus-host disease. His work integrates genomic evolution studies of gut bacteria, phage interactions, and microbial community assembly. Collaborations span microbiology, immunology, and translational medicine to develop diet-based therapies for intestinal health. Labs/Teams: Martens Lab (focusing on microbiome-metabolism-disease interfaces). Notable lab member: Qinnan Yang (postdoctoral researcher).

• Paediatric Inflammatory Bowel Disease
• Microbiome in IBD
• Clinical Outcomes Research
• +۴ مورد دیگر

Seamus Hussey is a Clinical Senior Lecturer at the Royal College of Surgeons in Ireland (RCSI), Department of Paediatrics and Child Health. He is also a Consultant Paediatric Gastroenterologist at Our Lady’s Children’s Hospital, Crumlin, Dublin. His primary research focus is on paediatric inflammatory bowel disease (IBD), particularly the microbiome in IBD, clinical outcomes, and novel therapeutic strategies. He leads the DOCHAS project (Determinants and Outcomes in Children and Adolescents with IBD) at the National Children’s Research Centre. Prof. Hussey is an elected member of the Porto IBD Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). His research interests include paediatric IBD epidemiology, host-microbial interactions, and translational therapies. He collaborates internationally on projects related to IBD pathogenesis and treatment efficacy. His recent publications highlight advancements in understanding IBD mechanisms, including neutrophil subsets’ role in intestinal disease and the impact of anti-TNF therapy in obese children with IBD. Prof. Hussey has secured grants for projects such as 'Engineered recombinant activated protein C as a novel therapeutic agent for children with IBD' and 'Outcomes of Modified Exclusive Elemental Nutrition in Paediatric Crohn’s Disease.' He is actively involved in clinical training, supervising Specialist Paediatric Registrar Trainees since 2015. Professional roles include Clinical Lead in Paediatric Gastroenterology and membership in the National Endoscopy Clinical Advisory Group. His work aligns with UN Sustainable Development Goal 3 (Good Health and Well-Being), focusing on improving paediatric gastrointestinal health outcomes globally.

Douglas G Burrinمشاهده پروفایل

استاد

• Neonatal Nutrition
• Gastroenterology
• Hepatology
• +۷ مورد دیگر

Douglas G. Burrin is a Professor in Pediatrics and Research Physiologist at the USDA-ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX. His primary focus is translational research on neonatal nutrition, particularly addressing gut and liver dysfunction in preterm infants. He leads the Fellowship Research Training program in Pediatric Nutrition and Gastroenterology. Education: PhD and MS from University of Nebraska; BS from Purdue University. Postdoctoral training at Baylor College of Medicine. Research Interests: Explores mechanisms of parenteral nutrition-associated liver disease (PNALD), necrotizing enterocolitis (NEC), and intestinal adaptation. Uses neonatal piglet models to study bile acid signaling, enteral/parenteral nutrition interactions, and GLP-2 hormone effects. Key areas include metabolic programming, lipid emulsion efficacy, and microbiome-gut interactions. Publications: Over 200 peer-reviewed articles focusing on PNALD pathophysiology, new lipid emulsions, GLP-2 signaling, and NEC prevention strategies. Recent work highlights the role of FGF19 and bile acid supplementation in neonatal liver health. Grants & Training: Leads NIH-funded studies on neonatal nutrition. Trains clinical researchers through fellowship programs. Expertise spans metabolic profiling, confocal microscopy, and stable isotope techniques. Labs/Teams: Directs a multidisciplinary lab integrating physiology, molecular biology, and metabolomics. Collaborates with clinical teams at Texas Children's Hospital and international research networks.

• Molecular Microbiology
• Bacteriology
• Host/Pathogen Interactions
• +۳ مورد دیگر

Dr. Jai Mehat is a Lecturer in Molecular Bacteriology at the University of Surrey’s School of Biosciences. He holds a PhD from the University of Surrey (2017) and specializes in molecular microbiology, bacteriology, and host-pathogen interactions. His research focuses on bacterial pathogen adaptation strategies, particularly in veterinary and medical contexts, combining genomic, genetic, and in vitro/in vivo models to develop non-antibiotic interventions such as vaccines, probiotics, and immune-modulators. Education: PhD in Molecular Bacteriology (University of Surrey, 2017), PGCert, and BSc. Research interests include avian colibacillosis, alternatives to antibiotics, and microbiome roles in livestock health. He leads teaching in the module BMS1035 Practical and Biomedical Bacteriology and supervises ongoing PhD projects on avian pathogenic E. coli evolution and non-antibiotic control strategies. His work spans bacterial genomics, antimicrobial resistance, and rapid diagnostic technologies for infectious diseases, including contributions to the VIDIIA Hunter diagnostic platform approved for UK medical use.

David Gomez Varelaمشاهده پروفایل

پژوهشگر

• Proteomics
• Chronic Pain
• Microbiome Interactions
• +۴ مورد دیگر

Dr. David Gomez Varela is a Senior Scientist at the University of Vienna's Department of Pharmaceutical Sciences, affiliated with the Division of Pharmacology and Toxicology. He holds a permanent position and directs the University of Vienna-Bruker Center of Excellence for Metaproteomics. His roles include leading interdisciplinary projects in proteomics, machine learning, and personalized health solutions. Previously, he worked at UC San Diego and the Max Planck Institute for Experimental Medicine, where he developed novel proteomic techniques like Data Independent Acquisition (DIA). Education: PhD in Biochemistry from Oviedo University (Spain), postdoctoral research in ion channel electrophysiology and microscopy at the Max Planck Institute (Germany), and senior scientist roles in the US and Germany. Research focuses on chronic pain mechanisms, host-microbiome interactions, and microbiome-driven drug discovery. Key projects include CODOP/COEWS algorithms for predicting COVID-19 outcomes and the SaLux pocket PCR machine. Recent publications emphasize proteomic profiling of pain signatures, microbiome interactions, and age/sex differences in neural tissues. Currently leads a team deploying DIA-PASEF mass spectrometry, ML analysis, and mouse behavior studies to identify chronic pain targets. The Center of Excellence for Metaproteomics collaborates with Bruker to advance LC-MS and AI for microbiome studies in health ecosystems. Grants and advising: Directed international teams in pandemic response projects, validated >40,000 patient data. Active in mentoring postdocs and PhD students in proteomics and systems biology. Labs/Teams: Director of the Vienna-Bruker Center, leading the Pharmacology & Toxicology Division's proteomics initiatives. Collaborates globally on translational medicine projects.

• Cytopathology
• Cancer Genetics
• Diagnostic Oncology
• +۳ مورد دیگر

Sue Ellen Martin, MD, PhD, is an Associate Professor of Pathology and Anatomic Pathology Chief at Keck Medical Center, University of Southern California (USC). Her expertise spans cytopathology, cancer genetics, and diagnostic oncology, with a focus on molecular pathology and imaging techniques. She has contributed to advancing diagnostic accuracy in breast cancer, thyroid nodules, and gastrointestinal cancers through clinical and translational research. Dr. Martin’s research integrates genetic analysis (e.g., UVRAG, BAP1 mutations) with clinical outcomes, emphasizing tumor biology and therapeutic decision-making. Her work on fine needle aspiration (FNA) techniques and ultrasound-guided biopsies has improved diagnostic protocols for breast, salivary gland, and thyroid pathologies. Her publications reflect a commitment to translational research, including studies on epigenetic reprogramming in transposed tissues and the clinical utility of imaging biomarkers. She has participated in randomized trials (e.g., soy intervention for breast density) and large-scale observational studies like the ACOSOG Z0040 trial in lung cancer. As a leader in anatomic pathology, Dr. Martin bridges clinical practice and research, contributing to improved diagnostic standards and personalized therapeutic approaches.

• Potassium Homeostasis
• Metabolic Syndrome
• Gut-Brain Axis
• +۳ مورد دیگر

Jang-Hyun Youn is an Associate Professor at the Keck School of Medicine, University of Southern California , specializing in Physiology & Neuroscience . His research focuses on potassium homeostasis , metabolic syndrome , and free fatty acid interactions , with recent work exploring green tea extracts and citrus compounds for sleep regulation . Current affiliation: Keck School of Medicine, USC Email: youn@usc.edu Research trends span nutritional physiology , ion transport modeling , and gut-liver-brain interactions , including stable isotope tracing of potassium fluxes and lipid mediator analysis in metabolic disorders.

• Biomedical Systems Biology
• Computational Biology
• Metabolic Networks Modeling
• +۴ مورد دیگر

Natal AW van Riel is a Professor of Biomedical Systems Biology at Eindhoven University of Technology (TU/e) and part-time Professor of Computational Modeling at Amsterdam University Medical Centers. His research focuses on computational modeling of metabolic networks, systems biology, and digital twins for cardiometabolic diseases like obesity and type 2 diabetes. He leads the Computational Biology group and the Systems Biology and Metabolic Diseases program at TU/e, emphasizing translational research integrating AI, physiology, and clinical data. Academically, van Riel holds a PhD from Utrecht University (2000) and has held positions from Assistant Professor (2003) to Associate Professor (2014) before becoming Full Professor (2019). He is also Head of the Computational Biology group (2023) and chairs TU/e's Biomedical Engineering Examination Committee. His work contributes to UN Sustainable Development Goals, particularly in health and nutrition. Research interests include bile acid metabolism, gut microbiome interactions, metabolic health indices (e.g., MHI), and digital twins for personalized medicine. Collaborations span clinicians, engineers, and AI specialists to translate models into clinical tools like the DiaGame diabetes management game. Notable achievements include the Dutch Royal Order of Orange-Nassau (2014) and leadership in projects like RESOLVE and ACACIA. He has supervised 104 research works and contributed to over 300 publications, emphasizing metabolic resilience, computational methods, and translational systems biology.

Marga Janseمشاهده پروفایل

مدرس

• Vaccine Development
• One Health
• Zoonosis
• +۵ مورد دیگر

Marga Janse is a Lecturer at the Athena Institute within the Faculty of Science at Vrije Universiteit Amsterdam. Her research focuses on vaccine development across human and veterinary fields, with a strong emphasis on One Health approaches to address zoonotic diseases like Respiratory Syncytial Virus (RSV) and Chlamydia. She also investigates barriers in vaccine R&D timelines and innovations in veterinary intestinal health. Her expertise spans topics such as cross-species vaccine utilization, intellectual property analysis in biotechnology, and antibiotic alternatives for zoonotic pathogens. Ancillary activities include serving as Director/Owner of Drogteropslagen since August 2018. She teaches courses on business management in health/life sciences and clinical development/trials. Recent research highlights include collaborative European studies on RSV vaccine development, patent landscape analyses in veterinary health, and evaluations of key barriers in vaccine R&D, including during the Covid-19 pandemic. Her work contributes to UN Sustainable Development Goals related to good health and well-being.

• Cell Biology
• Developmental Biology
• Stem Cell Research
• +۳ مورد دیگر

Anja Knaupp is a Research Fellow in the Department of Anatomy & Developmental Biology at Monash University . Her work focuses on transcriptional regulation, stem cell biology, and regenerative medicine, with a particular emphasis on cellular reprogramming and the epigenetic control of cell fate transitions. Recent research outputs include studies on: 2022 : Retrotransposon instability in iPSCs and spatial transcriptomics of the mammalian heart 2022 : Intestinal stem cell aging signatures and reprogramming strategies 2020 : Human induced trophoblast stem cell protocols Her projects are funded by the NHMRC and often involve collaboration with teams led by Prof. Jose Polo and Dr. Ryan Schittenhelm . She contributes to high-impact publications in journals like Nature and Nature Communications , with a focus on genomic stability and regenerative medicine applications.

Bernhard Hubeمشاهده پروفایل

استاد

• Candida Pathogenesis
• Fungal Virulence Factors
• Host-Pathogen Interactions
• +۲ مورد دیگر

Bernhard Hube leads the Department of Microbial Pathogenicity Mechanisms at Leibniz-HKI and holds the Chair in Microbial Pathogenicity at Friedrich Schiller University Jena. His pioneering research identified candidalysin as the first fungal cytolytic toxin, revolutionizing understanding of Candida mucosal infections. Work combines molecular microbiology with immunology to decipher host-fungal interactions. Research examines: 1) Candida albicans/glabrata virulence mechanisms, 2) Fungal adaptation to host niches including macrophages, 3) Toxin-mediated epithelial damage, and 4) Microbiome-pathogen dynamics. Recent studies characterize neutrophil extracellular trap induction by candidalysin and gut colonization strategies. Laboratory develops advanced infection models including organ-on-chip systems and 3D mucosal constructs. Collaborative projects span antifungal discovery and diagnostic tool development with industry partners. Contributes to WHO fungal priority pathogen lists and pan-European mycosis research initiatives.

• Molecular Biology
• Phage Biology
• Bacteriophage Research
• +۳ مورد دیگر

Prof. Dr. Alexander Harms is an Assistant Professor at the Department of Health Sciences and Technology, ETH Zürich. His research focuses on molecular phage biology, antibiotic resistance mechanisms, and bacterial defense systems. He leads studies on bacteriophage genomics, phage-host interactions, and the development of novel antimicrobial strategies. His work includes genome sequencing of bacteriophages, elucidating anti-phage defense mechanisms, and exploring phage evolution using automated systems. Notable contributions involve the BASEL phage collection and investigations into antibiotic tolerance in bacterial populations. Collaborations emphasize open science practices to improve biomaterial sharing in research. Recent articles highlight advancements in phage therapy, molecular mechanisms of bacterial resistance, and synthetic biology applications. His lab integrates genomic, structural, and ecological approaches to advance understanding of microbial systems and their therapeutic potential.

Julia Jeannine Mackمشاهده پروفایل

استادیار مدعو

• Vascular Biology
• Endothelial Cell Biology
• Lipid Metabolism
• +۳ مورد دیگر

Julia Jeannine Mack is an Assistant Adjunct Professor in the Department of Medicine at UCLA. Her research program focuses on vascular biology, endothelial mechanotransduction, and lipid metabolism. She investigates molecular pathways linking hemodynamic forces, cholesterol transport, and inflammatory responses in cardiovascular diseases. Her primary research interests include: Mechanisms of endothelial cell response to shear stress and mechanical stimuli Cholesterol metabolism and its impact on vascular inflammation Lipid-mediated signaling in atherosclerosis development Metabolic regulation of immune-vascular interactions Novel therapeutic targets for vascular protection Analysis of her recent publications reveals a strong emphasis on vascular mechanobiology, lipid metabolism, and inflammation. Her work consistently integrates molecular biology techniques with physiological models to explore endothelial adaptations to hemodynamic forces, cholesterol trafficking pathways, and their roles in atherosclerosis. The research demonstrates advanced methodologies including in vivo imaging, lipidomics, and genetic manipulation across multiple model systems.

• Lipid Metabolism
• Immunology
• Cancer Biology
• +۷ مورد دیگر

Steven J. Bensinger is a Professor in the Department of Microbiology, Immunology, and Molecular Genetics (MIMG) and the Department of Molecular and Medical Pharmacology at the University of California, Los Angeles (UCLA). He holds a VMD (Veterinary Medicine) from the University of Pennsylvania School of Veterinary Medicine and a PhD in Immunology from the University of Pennsylvania School of Medicine. His research focuses on understanding how lipid metabolism influences cell fate, with a particular emphasis on immune cells and cancer biology. Key areas include the role of lipids in inflammation, host defense, and cancer progression. Dr. Bensinger leads the Bensinger Lab, which employs cutting-edge techniques such as lipidomics and stable isotope labeling to study lipid metabolic pathways. His work has led to significant findings in areas like ferroptosis sensitivity in glioblastoma, cholesterol regulation in T cells, and the impact of lipid metabolism on tumor immunity. He has secured major grants from the NIH, including roles as Principal Investigator or Co-Investigator on projects related to lipid metabolism in diseases like atherosclerosis and cancer. Recent publications highlight his team's advancements in drug development (e.g., Tegavivint), metabolic reprogramming in immune cells, and the interplay between diet, lipid transport, and immune function. His interdisciplinary approach bridges basic science with translational research, aiming to translate metabolic insights into therapies for cancer, autoimmune disorders, and infectious diseases.