جست‌وجوی استاد و پژوهشگر

Josh Huangمشاهده پروفایل

استاد

• Neuroscience
• Neurogenetics
• Developmental Neurobiology
• +۵ مورد دیگر

Josh Huang is a Professor of Neurobiology, Cell Biology, and Biomedical Engineering at Duke University School of Medicine , where he leads the Huang Lab. His research focuses on the development and function of cortical circuits underlying motor control and cognitive processing , integrating genetic engineering, single-cell genomics, and behavioral neuroscience to address neuropsychiatric disorders. Education : PhD in Neuroscience, Brandeis University (1995) Research Areas : Huang’s work spans three synergistic domains: (1) cell type genetic tools (e.g., CellREADR for RNA-programmable cell targeting), (2) molecular genetic programs defining neuronal specification, and (3) cell type basis of motor-cognitive circuits . His team employs multi-omics, optogenetics, and naturalistic behavior paradigms to decode cortical architecture. Publications highlight trends in RNA-based neurotechnology , glutamatergic/projection neuron subnetworks , and GABAergic interneuron mapping . Notable contributions include the BRAIN Initiative Cell Census Network (BICCN) and CellREADR innovations. Scientific Awards : Election to the American Academy of Arts & Sciences (2022) NIH Director’s Pioneer High-Risk High-Reward Award Grants from NIMH, NIH BRAIN Initiative, and collaborative programs support his multidisciplinary investigations . The lab trains PhD students and postdoctoral fellows in neuroscience and biomedical engineering.

• Neuro-oncology
• Developmental Neuroscience
• Cancer Biology
• +۳ مورد دیگر

Rosalind Segal serves as Dean for Graduate Education at Harvard Medical School (HMS) since 2019 and is a Professor of Neurobiology with dual appointments at HMS and Dana-Farber Cancer Institute. Her leadership encompasses oversight of doctoral programs administered through Harvard Graduate School of Arts and Sciences and HMS-administered master's degree programs, with strategic priorities focused on student mentoring, diversity initiatives, and program cohesion. Dr. Segal's research program bridges neuroscience and cancer biology, investigating growth-factor pathways critical for brain development and their hijacking in brain cancers and neurological disorders. Her laboratory at Dana-Farber has made seminal contributions to understanding Sonic Hedgehog (SHH) medulloblastoma pathogenesis, chemotherapy-induced peripheral neuropathy mechanisms, and axon degeneration processes. Current work leverages CRISPR screening, single-cell RNA sequencing, and axonal translatome profiling to identify novel therapeutic targets. Her publication record demonstrates sustained focus on two interconnected research trajectories: (1) SHH-driven medulloblastoma mechanisms including epigenetic regulation (DNMT1, EYA phosphatases) and developmental heterogeneity, and (2) Chemotherapy-induced peripheral neuropathy involving BCL-w/IP3 receptor interactions, calcium signaling, and axonal protection strategies. Recent work increasingly integrates neuro-oncology with peripheral nervous system pathophysiology. NIH Director’s Pioneer Award Association of American Physicians membership HMS Harold Amos Faculty Award for Diversity As an educator, Dr. Segal has mentored undergraduates, graduate students (including neuroscience PhD and MD-PhD candidates), medical students in the Peabody Society, and Harvard freshmen. She previously directed the Harvard PhD Program in Neuroscience and chaired Dana-Farber's Department of Cancer Biology, demonstrating sustained commitment to academic leadership and trainee development across multiple educational levels.

• Neuroscience
• Synaptic transmission
• Presynaptic mechanisms
• +۷ مورد دیگر

Professor Peter Jonas is a leading neuroscientist at IST Austria, specializing in synaptic transmission mechanisms and their role in neural circuits. He holds the Magdalena Walz Professorship for Life Sciences and leads the Jonas Group, focusing on nanophysiological studies of synapses using advanced techniques like optogenetics and flash-and-freeze electron microscopy. His research bridges biophysical mechanisms with network functions in the hippocampus and cortex. Education & Career: MD, University of Giessen (1987) Professorships at University of Freiburg (1995–2010), Technical University of Munich (1994–1995), and currently at IST Austria since 2010 Research Interests: Synaptic signaling and plasticity at glutamatergic/GABAergic synapses Role of presynaptic calcium channels and vesicle dynamics Neural coding in hippocampal circuits Mechanisms of gamma oscillations via inhibitory interneurons Awards & Honors: ERC Advanced Grants (2010, 2016), Gottfried Wilhelm Leibniz Award (2006) Member of EMBO, Leopoldina Academy, and Academia Europaea Lab & Team: Jonas Group at IST Austria includes postdocs, PhD students, and technical staff Current projects: Mossy fiber synapse plasticity, synaptic ultrastructure, and in vivo network modeling

DeFelipe Javierمشاهده پروفایل

استاد پژوهشی

• Cerebral Cortex
• Comparative Neuroanatomy
• Neuroanatomy
• +۴ مورد دیگر

Javier DeFelipe is a Research Professor at the Instituto Cajal (CSIC, Spain), where he has led transformative research since 1991. His work focuses on cortical microorganization, synaptic connectivity, and technological advancements like FIB/SEM electron microscopy, contributing to understanding epilepsy and Alzheimer’s disease. Director of the Cajal Blue Brain Project (2009–present) Founded the Laboratorio Cajal de Circuitos Corticales (CSIC/Universidad Politécnica de Madrid) Expert in correlating electron microscopy with functional neuronal markers Research interests span cortical histology, synaptic organization in neurodegenerative diseases, and the historical intersection of neuroscience with art. His Laboratorio Cajal team integrates anatomists, physiologists, mathematicians, and computer scientists to develop tools for large-volume ultrastructural analysis. Scientific awards : PROSE Award (2019) for Cajal’s Neuronal Forest in Biomedicine and Neuroscience British Medical Association Best Illustrated Book Award (2018) Honorary Member of the American Association of Anatomists (2013) Cajal Medal and Krieg Cortical Kudos Award (1999)

• Neuroscience
• Stress Neurobiology
• Psychiatric Disorders (PTSD, Anxiety, Depression)
• +۳ مورد دیگر

Dr. Rachel D. Moloney is a Lecturer and Funded Investigator at the School of Pharmacy, University College Cork (UCC), Ireland. She holds a B.Sc. (Hons) in Biochemistry from UCC (2009), an M.Sc. in Neuropharmacology from the National University of Ireland, Galway (2012), and a Ph.D. in Psychiatry and Anatomy & Neuroscience from UCC (2014). Her postdoctoral research included roles at APC Microbiome Ireland, the University of Oklahoma Health Sciences Center, and the University of Cincinnati. She was awarded the prestigious NARSAD Young Investigator Award (2018) and the Pain Research Medal (2014). Her research focuses on stress neurobiology, particularly the role of traumatic stress on brain circuitry and empathy-related behaviors in PTSD, anxiety, and depression. She uses advanced tools like chemogenetics and viral vectors to study corticolimbic circuits. Her work also explores the gut microbiome’s bidirectional communication with the brain and spinal circuitry in stress-related illnesses. Dr. Moloney has secured grants such as the NARSAD Young Investigator Award (€70,000) and the OCNS Translational Research Grant. She contributes to journals like Molecular Psychiatry and Biological Psychiatry as a referee. Her teaching includes modules such as PT1445 and PF6421 in the School of Pharmacy. Education: B.Sc. Biochemistry, UCC (2009) M.Sc. Neuropharmacology, NUIG (2012) Ph.D., UCC (2014) Research Grants: NARSAD Young Investigator Award (€70,000) OCNS Translational Research Grant Her lab investigates stress-induced changes in brain circuits and the microbiota-gut-brain axis. Collaborators include Dr. Evelin Cotella (University of Cincinnati) and Prof. James P. Herman. She is affiliated with APC Microbiome Ireland and actively involved in neuroscience societies.

Kevin M. Wrightمشاهده پروفایل

پژوهشگر

• Neurodevelopment
• Axon Guidance
• Neuronal Migration
• +۲ مورد دیگر

Kevin M. Wright is an Associate Professor at the Vollum Institute , Oregon Health & Science University (OHSU). He earned a B.S. in Neuroscience (2001) from Allegheny College and a Ph.D. in Neurobiology (2006) from the University of North Carolina, Chapel Hill, followed by postdoctoral training at Johns Hopkins Medical Institute. PhD: University of North Carolina, Chapel Hill (Neurobiology, 2006) BS: Allegheny College (Neuroscience, 2001) His research focuses on neurodevelopment , particularly molecular pathways governing axon guidance , neuronal migration , and synaptogenesis in disorders like autism. He pioneered studies on Dystroglycan signaling and Tbr1 mutations. Recent work includes Cre-lox tools for cerebellar studies and PARP6 function in developmental delay. Articles span neurogenetics , synaptic biology , and retinal development , with high-impact studies in Nature Communications and Neuron . He has 31 publications and an h-index of 16 (Scopus). Collaborations include institutions like Johns Hopkins, UNC, and OHSU, with recurring co-authors in neurodevelopmental research (e.g., Brian J. O'Rоak, Joseph Leffler).

• Neurosciences
• Synaptic Plasticity
• Neurobiology
• +۳ مورد دیگر

Roles and Affiliations: Professor at the University of Helsinki, Faculty of Veterinary Medicine, Department of Veterinary Biosciences. Group Leader of the Synaptic Plasticity and Neuronal Synchronization research group. Supervisor for doctoral programs in Integrative Life Science, Clinical Veterinary Medicine, and Brain & Mind. Research Interests: Tomi Taira's research focuses on neurosciences, synaptic plasticity, and neuronal network development. His work explores mechanisms underlying synaptic maturation, kainate receptor function, and the impact of developmental processes like early life stress on neural circuits. He also contributes to translational research through initiatives like Helsinki One Health, which integrates veterinary, human, and environmental health research. Grants and Collaborations: Principal investigator on projects funded by the Jane and Aatos Erkko Foundation and the Academy of Finland. Collaborates internationally on studies involving neuronal synchronization, GABAergic transmission, and antidepressant mechanisms. Labs and Teams: Leads the Synaptic Plasticity and Neuronal Synchronization group, focusing on experimental and computational approaches to understand network dynamics in health and disease.

Douglas S. F. Lingمشاهده پروفایل

دانشیار

• Neurotrauma
• Cortical Circuit Physiology
• GABAergic Inhibition
• +۹ مورد دیگر

Dr. Douglas S. F. Ling is an Associate Professor in the Department of Physiology and Pharmacology at SUNY Downstate Health Sciences University. His research focuses on Trauma-induced changes in cortical circuit physiology GABAergic inhibition mechanisms in post-TBI neuropathology Development of radiofrequency-based neural signal detection methods Research interests include understanding how traumatic brain injury disrupts the balance between excitatory and inhibitory neural circuits, leading to conditions like posttraumatic epilepsy. His work explores nootropic agents' effects on GABA receptor modulation and therapeutic interventions for neurotrauma. Recent publications highlight discoveries such as: 2024: Extracellular volume pulsations linked to epileptiform activity via NBCe1 transporters 2023: Brivaracetam's preventive role against posttraumatic epileptogenesis 2022: Electrophysiological validation of levetiracetam's neuroprotective timing Methodologically, his lab employs In vitro and in vivo TBI models Electrophysiology Behavioral testing Advanced microscopy with emphasis on early intervention windows for neuroprotective treatments.

Divakar S Mithalمشاهده پروفایل

استادیار

• Pediatric Neurology
• Neurocritical Care
• Mitochondrial Diseases
• +۳ مورد دیگر

Divakar S Mithal, MD, PhD, serves as Assistant Professor in Pediatrics (Neurology and Epilepsy) at Northwestern University Feinberg School of Medicine and practices at Ann & Robert H. Lurie Children's Hospital of Chicago. His dual expertise spans clinical neurocritical care for critically ill children and research on brain metabolism disorders, with additional affiliations at the Center for Human Immunobiology, NUCATS, and Simpson Querrey Institute for Epigenetics. Education BS, Massachusetts Institute of Technology (2001) PhD, Northwestern University Feinberg School of Medicine (2011) MD, Northwestern University Feinberg School of Medicine (2013) Residency in Pediatrics, Northwestern University (2015) Residency in Child Neurology, Northwestern University (2018) Fellowship in Pediatrics Neuro-Critical Care, Northwestern University (2019) Dr. Mithal's laboratory investigates fundamental mechanisms of cellular metabolism in neurological disorders, focusing on four interconnected projects: mitochondrial function in GABAergic interneurons, metabolic biomarkers in mitochondrial disease patients' white blood cells, gene-therapy development for mitochondrial disorders, and drug screening using patient-derived stem cells. His research bridges immunology and neuroscience through chemokine signaling pathways, aiming to develop neuroprotective strategies for conditions like refractory seizures and septic encephalopathy. Recent publications (2024-2025) demonstrate a cohesive research trajectory spanning pediatric neurology, metabolic disorders, and critical care. Key themes include neuroimaging analysis in cerebral palsy and stroke, molecular characterization of mitochondrial diseases, and genetic variant validation in neurometabolic conditions. These works consistently integrate clinical observations with laboratory investigations to address therapeutic gaps in pediatric neurological emergencies. Scientific Awards Elterman Research Award, Child Neurology Foundation (2023) As Medical Advisory Board Chair for MitoWorld and Scientific Advisory Board Member for the United Mitochondrial Disease Foundation, Dr. Mithal shapes national research priorities while leading neurogenetics clinics at Lurie Children's Hospital. His clinical practice centers on frontline neuroprotection during critical illness decompensation, applying the 'time is brain' principle to minimize neurological injury in high-acuity pediatric ICU settings.

• Neuroscience
• Neural Development
• Stem Cell Research
• +۳ مورد دیگر

Irina Korshunova is a PhD Staff scientist working in the Khodosevich Group at the Biotech Research and Innovation Centre (BRIC) within the University of Copenhagen's Faculty of Health and Medical Sciences. She maintains an active research profile with numerous publications in high-impact neuroscience journals. Her research focuses on neural development, particularly examining interneuron development, stem cell research, and neurological disorders. Dr. Korshunova's work investigates the cellular and molecular mechanisms underlying conditions like Tuberous Sclerosis Complex, with emphasis on GABAergic regulation, astrocyte function, and the effects of maternal inflammation on neural development. Her research employs advanced techniques including single-cell transcriptomics and genetic modification approaches. Analysis of her recent publications (2019-2024) reveals a consistent focus on neurological disorders, with particular attention to Tuberous Sclerosis Complex, interneuron subtypes, and cellular mechanisms of neurodevelopment. Her work bridges molecular neuroscience with clinical implications, often exploring potential therapeutic approaches through stem cell research and neuroregeneration. Her publications have garnered significant attention in the scientific community, with multiple articles picked up by news outlets and accumulating substantial readership on academic platforms like Mendeley. One of her 2020 papers in Molecular Psychiatry has been particularly influential with 179 readers on Mendeley and referenced by Bluesky users. Dr. Korshunova works within the Khodosevich research group, which appears to be a productive neuroscience laboratory focusing on neural development, interneuron biology, and neurological disorders. The group maintains active collaborations across multiple institutions as evidenced by the diverse author lists on publications and the international attention their work receives.

Guoping Fengمشاهده پروفایل

استاد

• Neuroscience
• Neurodevelopmental Disorders
• Psychiatric Diseases
• +۳ مورد دیگر

Guoping Feng is the James W. Poitras Professor of Brain and Cognitive Sciences at MIT and Associate Director of the McGovern Institute for Brain Research. He leads the Hock E. Tan and K. Lisa Yang Center for Autism Research and directs the Model Systems and Neurobiology group at the Stanley Center for Psychiatric Research. His work focuses on synaptic mechanisms underlying neurodevelopmental and psychiatric disorders, including autism and schizophrenia, using molecular genetics and electrophysiological methods. Research Interests: Synaptic function, neurocircuit development, psychiatric disorders, gene therapy, and non-human primate models (e.g., marmosets). Active projects include mapping cellular diversity in the brain and developing genetic tools for neuroscience. Key Achievements: Pioneered gene-based therapy for SHANK3-related autism, demonstrating reversal of symptoms in animal models. His lab has advanced CRISPR-based technologies and studies thalamic circuitry in Parkinson’s and schizophrenia. Affiliations: Broad Institute of MIT and Harvard, Simons Center for the Social Brain, and McGovern Institute for Brain Research. The lab emphasizes diversity and inclusion, fostering a collaborative environment.

Junchul Kimمشاهده پروفایل

دانشیار

• Behavioural Neuroscience
• Cognitive Neuroscience
• Neural Circuits
• +۳ مورد دیگر

Junchul Kim is an Associate Professor at the University of Toronto with primary appointment in the Psychology Department and cross-appointment in Cell and Systems Biology. His research focuses on elucidating hippocampal circuits and GABA interneuron functions in anxiety, stress, and memory processes using optogenetic and chemogenetic approaches. PhD in Molecular Biology and Biochemistry, Simon Fraser University (2005) Postdoctoral Research Fellow, Harvard Medical School (2005-2010) Kim's laboratory investigates two major areas: (1) Functional specialization of hippocampal pathways in emotional and cognitive control, and (2) Distinct roles of PV- and CCK-GABA interneuron subtypes in neural oscillations and behavioral modulation. His work has produced significant insights into hippocampal-prefrontal connectivity and anxiety-related circuitry. Key methodological contributions include developing recombinase-based genetic tools for noninvasive neuron labeling and silencing. Current research explores how specific neural circuits coordinate defensive responses and maintain memory stability across behavioral contexts. The Kim Lab actively trains graduate students in neuroscience research and offers opportunities for postdoctoral fellows. Current students include Cindy Hong, Kendall Mar, Andrew Cheon, Ruth Tran, Stephanie Shishis, and Charlotte Romain, while lab alumni feature notable researchers like Afif Aqrabawi and Paul Whissell.

Yang Danمشاهده پروفایل

استاد

• Neuroscience
• Sleep Research
• Neurophysiology
• +۳ مورد دیگر

Yang Dan is a Professor of Molecular Therapeutics and a Howard Hughes Medical Institute Investigator. Her research focuses on elucidating the neural circuits controlling sleep and the mechanisms of prefrontal cortex top-down executive control. She employs techniques such as optogenetics, electrophysiology, and viral circuit tracing. Research Interests Yang Dan's work investigates the mammalian brain circuits regulating sleep, particularly REM and non-REM sleep, and the functional dynamics of the prefrontal cortex in behavioral control. Her team uses advanced methods like optrode recording, calcium imaging, and viral tools for neuronal mapping. Publication Trends Her recent publications (2012–2020) emphasize sleep regulation via hypothalamic and midbrain circuits, prefrontal cortex dynamics, and optogenetic approaches to understanding neuronal activity in behavior. Scientific Awards Howard Hughes Medical Institute Investigator Nan Fung Life Sciences Chancellor's Chair in Neuroscience Yang Dan's research integrates interdisciplinary methodologies to address fundamental questions in neuroscience, with implications for sleep disorders and cognitive dysfunction.

Gord Fishellمشاهده پروفایل

استاد

• Neurobiology
• Developmental Neuroscience
• Neural Circuitry
• +۵ مورد دیگر

Gord Fishell, Ph.D., is a Professor of Neurobiology at Harvard Medical School. His research focuses on the developmental mechanisms underlying inhibitory interneuron diversity and their integration into neural circuits, with implications for autism spectrum disorder, schizophrenia, and intellectual disability. His laboratory has pioneered tools like enhancer-AAV viral vectors for targeting interneurons across species, enabling precise manipulation of cortical circuits. Research Themes: Interneuron Specification: Genetic programs governing interneuron subtype generation during embryonic development. Circuit Integration: Local cues guiding interneurons into cortical and subcortical circuits. Pathophysiological Links: Investigating how interneuron dysfunction contributes to neurological disorders. Technological Innovation: Developing viral tools for cell-type-specific manipulation in mammals and humans. Key Contributions: The lab's work on somatostatin (SST) and parvalbumin (PV) interneurons has revealed critical roles in circuit maturation and sensory processing. Their viral toolkit, developed with Paola Arlotta, enables targeted studies of diverse cortical cell types. Future Directions: Translating developmental insights into therapies for neurodevelopmental disorders, particularly through interneuron-based interventions.

• Neurodevelopmental Biology
• Immunology
• Neuroscience
• +۳ مورد دیگر

Simona Lodato is an Associate Professor at Humanitas University and Group Leader of the Developmental Neurobiology Lab at Humanitas Research Center. Her research focuses on neurodevelopmental disorders, particularly the interplay between immune dysfunction and brain abnormalities in conditions like WHIM syndrome. She investigates the role of the CXCR4 gene in cerebellum development and immune system regulation using advanced techniques such as organoids, genomic analysis, and high-resolution imaging. Dr. Lodato earned her Ph.D. from the European School of Molecular Medicine (SEMM) and the University of Naples Federico II, followed by postdoctoral work at Harvard University under Prof. Paola Arlotta. She has pioneered studies on corticospinal motor neuron identity and the assembly of functional neural circuits. Her work bridges molecular mechanisms with translational medicine, aiming to develop therapies for genetic disorders. Key achievements include a multi-round grant from Fondazione Telethon to study WHIM syndrome and her role as an advisor to the Allen Brain Institute’s Next Generation Leader Council. Her research explores therapeutic strategies for spinal muscular atrophy, Charcot-Marie-Tooth disease, and ALS using organoid models and genetic interventions. Dr. Lodato’s lab employs multidisciplinary approaches, integrating stem cell biology, epigenetics, and neuroimaging to uncover how genetic mutations impact brain and immune system development. Ongoing projects aim to translate these findings into clinical treatments for rare diseases.