جستجوی استاد راهنمای دانشگاهی

Alexei G. Basnakianمشاهده پروفایل

استاد

• Cell Death Mechanisms
• DNA Degradation in Disease
• Renal Tubular Epithelium Injury
• +۳ مورد دیگر

Dr. Alexei G. Basnakian is a Professor in the Department of Pharmacology and Toxicology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. He also serves as a Research Career Scientist at the Central Arkansas Veteran’s Healthcare System. His research focuses on the role of DNases in cell death mechanisms, particularly in kidney injury, cancer therapy, and toxicology. He holds a Medical Doctorate from Sechenov Moscow Medical Academy (1976), a Ph.D. from the USSR Academy of Medical Sciences (1981), and completed a postdoctoral fellowship at Harvard Medical School (1988–1989). Dr. Basnakian leads a research team investigating DNase-mediated DNA fragmentation in acute kidney injury, ischemia, and chemotherapy response. His work emphasizes developing DNase inhibitors to protect tissues or selectively target cancer cells. Key grants include VA Merit Review (2019–2023), USDA-AFRI (2018–2022), and NIH/NIGMS COBRE grants (2015–2021). He has mentored numerous researchers and collaborated on projects involving nanomaterial toxicity, radiation countermeasures, and antimicrobial agents. His research spans drug development (e.g., thiazole-androstenone derivatives for melanoma), radiation-induced injury mitigation, and novel antibiotics targeting Gram-positive bacteria. He has published extensively in Nature Communications , International Journal of Molecular Sciences , and Journal of Medicinal Chemistry , among others. Ongoing projects include DNase-targeted therapies for rhabdomyolysis and bone fragility prevention. Grants & Leadership: Core Director (NIGMS P20 COBRE), Principal Investigator (VA Merit Review), Subcontract PI (USDA-AFRI) Key Themes: DNase biology, kidney protection, antimicrobial drug design, radiation biology Collaborative Networks: UAMS Pepper Center, Arkansas INBRE, Veteran’s Health System

Yunmeng Liuمشاهده پروفایل

استادیار

• Metabolic Syndromes
• Diabetes Pathogenesis
• Cardiovascular Disease
• +۶ مورد دیگر

Yunmeng Liu, Ph.D., is an Assistant Professor in the Department of Pharmacology and Toxicology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. Her research focuses on metabolic syndromes, particularly diabetes-linked cardiovascular complications and hypertension. She leads studies on immune cell contributions to hypertension pathogenesis using advanced techniques like radio-biotelemetry and 3D microscopy. Liu’s work integrates immunology, endocrinology, and molecular biology to develop therapeutic strategies. Education & Training: Ph.D. in Pharmacology, New York Medical College (2013) Postdoctoral Training at UAMS Rusch Laboratory (2019) Research Interests: Exploring how diabetes exacerbates cardiovascular disease and hypertension through metabolic reprogramming. Current projects investigate T cell interactions in kidney and heart tissues, immune pathways (e.g., IFNγ-PDL1), and cellular mechanisms driving salt-sensitive hypertension. Collaborations span immunology and physiology fields. Grants: Sturgis Foundation Grant (2024–2024): $50K, PI for 'Diabetes promotes hypertension via metabolic reprogramming' NIH R01 HL146713 (2024–2029): Major contributor to 'T cell homing to the kidney' Labs/Teams: Leads a multidisciplinary lab using cutting-edge tools like Seahorse assays and multi-color flow cytometry. Collaborates with the Rusch laboratory and immunology experts at UAMS.

• Mucosal Immunology
• Gastroenterology
• Innate Immunity
• +۴ مورد دیگر

Gianluca Matteoli is an Associate Professor at KU Leuven's Faculty of Medicine, affiliated with the Department of Chronic Diseases and Metabolism. He is a member of the Leuven One Health Institute and LISCO (KU Leuven Institute for Single Cell Omics). His research focuses on mucosal immunology, gastroenterology, innate immunity, intestinal motility, and the enteric nervous system. He serves as Promotor/Co-Promotor in several high-impact projects, including targeting fibroblasts in colorectal cancer and investigating the role of fat in Crohn's disease. He teaches courses such as 'Hot Topics in Gastroenterology' and 'Advances in Gastroenterology.' Recent projects include exploring enteric glia- immune cell synergy in intestinal inflammation resolution (2025-2028) and developing drug-like FAPIs for oncology and fibrosis (2024-2028). He leads the Translational Research in GastroIntestinal Disorders group and contributes to the KU Leuven Flow Cytometry core facility. His work bridges basic science and clinical applications in gastrointestinal disorders.

• Environmental Engineering
• Biorefinery
• Wastewater Treatment
• +۴ مورد دیگر

Jeremy S Guest is a Civil and Environmental Engineering Professor and David C. Crawford Faculty Scholar at the University of Illinois. He holds additional roles as Levenick Professor and Director of the Levenick Center for a Climate-Smart Circular Bioeconomy, and serves as Associate Director for Research at the Institute for Sustainability, Energy, and Environment. He is also an Affiliate of the Center for Social & Behavioral Science. His research focuses on sustainable biofuels, resource recovery from wastewater, and circular economy systems. Key areas include biorefinery design, life cycle assessment, and innovative sanitation technologies. Guest’s work emphasizes integrating environmental sustainability with economic feasibility, particularly in contexts like decentralized water reuse systems and non-sewered sanitation solutions. Recipient of the AEESP Teaching Award (2019), NSF CAREER Award (2014), and Paul L. Busch Award (2016). Leads the Levenick Center, advancing climate-smart bioeconomy strategies. Research collaborations span global sustainability challenges, including U.S. Army installation water reuse and regional bioenergy crop optimization. His articles highlight advancements in hydrothermal valorization of organic wastes, techno-economic analyses of biofuel production, and microbial community dynamics in wastewater systems.

• Pathology
• Pediatrics
• Immunology
• +۱ مورد دیگر

Dr. Maurice R.G. O'Gorman is Professor of Pathology and Pediatrics (Clinical Scholar) at the University of Southern California. His clinical research specializes in immunological diagnostics, particularly flow cytometry applications for primary immunodeficiencies. Affiliated with Children's Hospital Los Angeles.

• Hematology
• Oncology
• Leukemia
• +۲ مورد دیگر

Eric Tam is an Assistant Professor of Clinical Medicine specializing in hematology and oncology. His research focuses on leukemia treatments, stem cell transplantation, and immunotherapy approaches. With extensive publications in hematologic malignancies, he investigates novel therapeutic combinations, transplant protocols, and management of treatment complications. His research centers on optimizing outcomes for leukemia patients through precision medicine approaches, including targeted therapies like venetoclax and kinase inhibitors. Key interests include CAR-T cell therapy, measurable residual disease detection, and ethnic disparities in transplant outcomes. Publication analysis reveals predominant focus on hematologic malignancies (88%), particularly acute leukemias (73%). Recent works emphasize immunotherapy integration (31%) and transplant optimization (25%). Methodologies include clinical case studies (56%), retrospective analyses (25%), and literature reviews (19%).

• Hematology
• Oncology
• Stem Cell Transplantation
• +۱ مورد دیگر

Dr. George Yaghmour is a Clinical Associate Professor of Medicine at the University of Southern California, specializing in hematology, oncology, and stem cell transplantation. His clinical focus includes acute leukemia treatment and allogeneic bone marrow transplantation. His research examines novel therapeutic approaches for hematologic malignancies, particularly acute leukemias. Key areas include immunotherapy regimens, targeted therapies, and stem cell transplantation protocols. He maintains active clinical trials investigating CAR T-cell therapies and combination treatments for refractory leukemias. Recent publications demonstrate expertise in Philadelphia chromosome-positive leukemias, graft-versus-host disease prophylaxis, and measurable residual disease monitoring. His work consistently addresses treatment optimization for high-risk patient populations. Scientific Awards: Top Doctors in Southern CA Rising Stars (2017) Outstanding Fellow Award, Tennessee Oncology Practice Society (2015) Scholarship Award, Asheville Hematologic Malignancies Symposium (2015) Star Team Award, VAMC Memphis (2014) Top 5% Internal Medicine Residents, Wayne State University (2013) Outstanding Patient Satisfaction/Care, Henry Ford Hospital (2012) Top 1% Graduate Award, Aleppo University School of Medicine (2008) He leads clinical research initiatives through the Jane Anne Nohl Division of Hematology and mentors fellows in translational leukemia research.

John Bertramمشاهده پروفایل

استاد

• Kidney Disease
• Nephrology
• Developmental Biology
• +۶ مورد دیگر

John Bertram is a Professor in the Department of Anatomy & Developmental Biology at Monash University, affiliated with the Monash Biomedicine Discovery Institute. His expertise focuses on kidney structure and development, particularly nephron and glomeruli counts, which are critical for understanding chronic diseases. He pioneered quantitative kidney pathology, analyzing thousands of kidney samples globally to establish baseline nephron/glomeruli numbers and their variability. His work highlights environmental and genetic influences on kidney development, with implications for hypertension, kidney disease, and public health. Key projects include investigating low nephron endowment's role in chronic diseases, podocyte biology, and using MRI for 3D kidney analysis. He collaborates internationally, including NIH-funded research on renal regeneration. Grants include NHMRC support for podocyte-stem cell studies. His research contributes to UN SDGs addressing health and well-being. Research interests span kidney development, developmental origins of disease, and translational therapies. Recent work explores 3D imaging, podocyte depletion, and obesity-related glomerulopathy outcomes. Collaborations span institutions like the Australian Regenerative Medicine Institute and Howard Florey Institute.

• Immunology
• HLA
• T cell receptors
• +۵ مورد دیگر

Stephanie Gras is an Adjunct Professor (Research) in Biochemistry & Molecular Biology at Monash University, affiliated with the Monash Biomedicine Discovery Institute. Her research focuses on understanding viral recognition by the immune system, particularly mechanisms of viral escape and strategies for vaccine/drug development against pathogens like HIV and influenza. Primary affiliation: Monash University Research areas: Immunology, HLA, T cell receptors, viral infections Her work contributes to UN Sustainable Development Goals related to health and well-being. Notable projects include studies on HIV controllers' T cell responses and SARS-CoV-2 immune maintenance in populations. Awards include the ARC Future Fellowship (2012), Georgina Sweet Awards (2017), and Monash Research Fellowship (2011). Recent collaborations involve international teams studying viral immunology and antiviral strategies. Projects span HIV immunology, SARS-CoV-2 epidemiology, and lipid antigen presentation mechanisms.

Luise Cullen-McEwenمشاهده پروفایل

پژوهشگر ارشد

• Kidney Development
• Embryogenesis
• Nephron Development
• +۳ مورد دیگر

Dr. Luise Cullen-McEwen is a Research Fellow in the Department of Anatomy and Developmental Biology at Monash University, within the School of Biomedical Sciences. Her research focuses on kidney development, particularly the regulation of branching morphogenesis and nephron number during embryogenesis. She holds a PhD from Monash University (2002) and has extensive expertise in techniques like immunofluorescence, histology, and unbiased stereology. Her work includes projects funded by the Australian Kidney Foundation and NHMRC, investigating maternal diabetes effects on kidney development and chronic kidney disease progression. Key collaborations involve Jikei University Hospital and researchers in Japan. She has led projects addressing nephron deficits in premature offspring and the impact of maternal nutrition on kidney structure. Research interests span GDNF signaling in kidney development, podocyte adaptation, and the role of maternal conditions (e.g., diabetes, protein restriction) in programming renal deficits. Over 70 publications highlight her contributions to nephrology and developmental biology.

Alejandra Gutiérrezمشاهده پروفایل

پژوهشگر ارشد

• Immunology
• Cancer Research
• Macrophage Immunobiology
• +۳ مورد دیگر

Alejandra Gutiérrez is a Postdoctoral Scientist at the Spanish National Research Council (CSIC), working in Carlos Ardavin's laboratory at the Centro Nacional de Biotecnología (CNB) in Madrid, Spain. She holds a PhD from the University Autónoma of Madrid awarded in 2016 and has specialized expertise in tumor immunology and macrophage biology. Her academic background includes: PhD from University Autónoma of Madrid (2016) Dr. Gutiérrez's research centers on in vivo tumor development models and macrophage immunobiology , with advanced technical proficiency in confocal microscopy, cell biology methodologies, and flow cytometry. Her work investigates tumor microenvironment dynamics and immune cell interactions, contributing to oncology and immunology fields through experimental models of cancer progression. Her scientific recognition includes: Juan de la Cierva fellowship (2019) AECC postdoctoral fellowship (2021) As a postdoctoral researcher in the Ardavin lab, she actively contributes to ongoing immunology and oncology projects while collaborating with PhD students including Margarita Ferriz, Natalia Martínez, and Natalia Álvarez. Her research is funded through competitive fellowships rather than担任 primary advisor roles. She operates within CSIC's Immunology and Oncology research framework at CNB, focusing on translational cancer immunology applications.

Amanda Fortes Franciscoمشاهده پروفایل

استادیار

• Parasitic Diseases
• Drug Discovery
• Trypanosoma Pathogenesis
• +۳ مورد دیگر

Dr. Amanda Fortes Francisco is Assistant Professor in the Department of Infection Biology at the London School of Hygiene & Tropical Medicine. She holds an MSc and PhD in Biological Sciences from the Federal University of Ouro Preto, Brazil, with expertise in parasitic disease pathogenesis and drug discovery. Her research utilizes advanced in vivo imaging systems to study Trypanosoma cruzi and Trypanosoma brucei, focusing on Chagas cardiomyopathy and Environmental Enteric Dysfunction (EED). Her primary research areas include: Chagas disease pathogenesis with focus on inflammation and fibrosis In vivo imaging technology for tracking disease progression High-throughput screening for neglected disease drug discovery Interdisciplinary collaborations to accelerate therapeutic development Dr. Francisco's 15 most recent publications demonstrate consistent focus on therapeutic interventions for trypanosome infections, with emerging themes including: Combination therapies for chronic Chagas disease Novel drug mechanisms targeting topoisomerases and DNA Validation of animal models for pathogenesis studies Application of bioluminescent imaging in efficacy evaluation She serves in multiple institutional roles: Academic Lead for In Vivo Imaging Systems Member of Animal Welfare and Ethical Review Board Member of Flow Cytometry and Imaging Focus Group Member of Genetic Modification Safety Committee Her teaching portfolio includes: Tutor for Distance Learning modules (IDM601, IDM203) Lecturer on Molecular and Cell Biology of Infectious Disease Supervisor of MSc research projects Trainer in animal and histological techniques

Karl Ekwallمشاهده پروفایل

استاد

• Epigenetics
• Chromatin Remodeling
• Cellular Quiescence
• +۴ مورد دیگر

Karl Ekwall is a Professor at the Department of Medicine, Huddinge, Karolinska Institutet. He leads the research group 'Epigenetics - basic mechanisms and disease,' focusing on chromatin regulation in fission yeast and human cell lines. His work bridges basic research on epigenetic mechanisms (e.g., histone modifications, chromatin remodeling) with applied cancer epigenetics, particularly in leukemia. Key affiliations include the Swedish Epigenetics Network (founded in 2007) and collaborations with clinical research groups at KI. Education: Doctor of Philosophy (Molecular Biology), Uppsala University, 1994 Bachelor of Microbiology, Uppsala University, 1988 Research Interests: Ekwall's group investigates epigenetic control of cellular processes such as quiescence, differentiation, and disease. They study mechanisms like histone acetylation/methylation, nucleosome remodeling (via CHD1/INO80 complexes), and RNAi-directed silencing. Current projects include chromatin regulation in cancer and the role of SNF2 enzymes in blood cell differentiation. Grants and Funding: Swedish Research Council grants for epigenetics and chromatin remodeling (2014-2024) Swedish Cancer Society funding for studies on chromatin enzymes and cancer therapy (2015-2024) Awards: Göran Gustafsson Prize in Molecular Biology (2009) Royal Swedish Academy of Sciences Research Fellow (2007) Advising and Lab: Ekwall mentors students, including Shengyuan Zeng (PhD student). His lab employs genome-wide chromatin analysis techniques and collaborates internationally (e.g., with Bordeaux University and Nagoya City University).

• Autoimmunity and Inflammation
• Immunology
• Cancer Research
• +۴ مورد دیگر

Mikael Karlsson is a Professor at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet. His research focuses on the regulation of the immune system, particularly B cells and macrophages, in autoimmune diseases and cancer. He leads the 'Inflammatory responses in cancer and autoimmunity' research group, which investigates mechanisms underlying autoimmunity, allergy, cardiovascular disease, and tumor microenvironments. Education: Docent (2009), Karolinska Institutet. Active collaborations include institutions such as the University of Toronto, Rockefeller University, and NIH. His group employs advanced techniques like multiphoton microscopy and flow cytometry. Research Interests: Autoimmunity (e.g., systemic lupus erythematosus), cancer immunology, B cell and macrophage interactions, and immunotherapy development. Key projects include targeting TAM macrophages in tumors and studying B cell dysregulation in autoimmune conditions. Publications: Over 100 articles in journals like Cancer Cell , Nature Communications , and Immunity , highlighting work on immune tolerance mechanisms, extracellular vesicle therapies, and cytokine signaling. Lab & Collaborations: Hosts PhD students and collaborates globally. Focus areas include developing novel treatments for autoimmune diseases and cancer through immune modulation.

Karin Loréمشاهده پروفایل

استاد

• Vaccination Immunology
• Innate Immunity
• Vaccine Adjuvants
• +۴ مورد دیگر

Karin Loré is a Professor at Karolinska Institutet, leading the research group 'Understanding mechanisms of vaccination' within the Department of Medicine, Solna. Her work focuses on elucidating how the immune system responds to vaccines, particularly emphasizing adjuvants, mRNA technologies, and B cell responses. She holds a Doctor of Philosophy (2001) and a Licentiate degree (1999) from Karolinska Institutet, and became a Docent in 2010. Research Interests: Vaccination immunology and innate immunity Mechanisms of vaccine adjuvants and nanoparticle-based vaccines Broadening antibody responses for HIV, malaria, and respiratory viruses Immune responses in immunocompromised patients Her lab's work spans from basic immunology to translational studies, leveraging computational tools for analyzing high-dimensional immunological data. Collaborations include institutions like the NIH, CureVac AG, and Novavax. Current projects explore mRNA vaccine efficacy, adjuvant development, and immune correlates in chronic diseases. Funding sources include the Swedish Research Council, Bill & Melinda Gates Foundation, and the Knut and Alice Wallenberg Foundation. She advises numerous PhD students and postdocs, with alumni contributing to vaccine research globally. Laboratory activities include the 'Laboratory of Lymphocyte Biology' (led by Taras Kreslavskiy) and computational immunology pipelines. Her research has direct implications for developing vaccines against emerging pathogens like SARS-CoV-2 variants and neglected diseases such as malaria.