جستجوی استاد راهنمای دانشگاهی

• Ribonucleic acid (RNA)
• Data Analysis
• Bioinformatics
• +۱۲ مورد دیگر

Erik Dassi is an Associate Professor at the Department of Cellular, Computational and Integrative Biology (CIBIO) within the University of Trento. His research focuses on RNA biology, particularly investigating RNA structure-functional relationships, translational control mechanisms, and their implications in cancer, neurodegenerative diseases, and genetic disorders. He specializes in exploring how RNA modifications, G-quadruplex structures, and post-transcriptional regulatory networks drive disease processes and therapeutic resistance. Teaching activities include courses on Computational Biology, Cancer Genomics, Genomics Technologies, Programming, and Scientific Programming. His work emphasizes integrative approaches combining experimental and computational methods, such as polysomal profiling, allele-specific proteomics, and single-cell transcriptomics. Key research themes include: RNA G-quadruplex regulation of mitochondrial translation and energy metabolism ( n =3 articles in 2025), YTHDF proteins as tumor drivers in m6A pathways ( n =2 articles in 2024), and circular RNA roles in Huntington’s disease ( n =4 articles across 2021-2024). His work highlights translational reprogramming in cancer therapy resistance and RNA-based biomarker discovery.

Masad J. Damhaمشاهده پروفایل

استاد

• Chemical Biology
• Nucleic Acid Chemistry
• Biotechnology
• +۲ مورد دیگر

Masad J. Damha is a Distinguished James McGill Professor in the Department of Chemistry at McGill University. He holds a B.Sc. (1983) and Ph.D. (1988) from McGill University and completed postdoctoral training at the California Institute of Technology. His research bridges chemical biology and synthesis/catalysis, focusing on the chemical synthesis, biochemical properties, and molecular behavior of nucleosides, nucleic acids, and their analogues, with applications in biotechnology including siRNA, antisense oligonucleotides, and aptamers. Research Interests: Professor Damha's work explores inter- and intracellular communication between nucleic acids and proteins, particularly investigating how chemically modified nucleic acids (e.g., ANA, 2’F-ANA) can enhance therapeutic efficacy. His research aims to develop novel strategies for genetic regulation and diagnostic tools through engineered nucleic acid systems. Honors and Awards: R.U. Lemieux Award (CIC, 2020) Queen Elizabeth II Diamond Jubilee Medal (2012) Bernard Belleau Award (CSC/CIC, 2007) Merck-Frosst Award for Therapeutic Research (1999) Fellow of the Chemical Institute of Canada (FCIC, 1999) John Charles Polanyi Chemistry Prize (1989) Leo Yaffe Award for Excellence in Teaching (2011-12) David Thomson Award in Graduate & Teaching (2010) Teaching and Leadership: Professor Damha teaches Introductory Organic Chemistry (CHEM 302) and Advanced Nucleic Acid Chemistry (CHEM 542). He has held leadership roles as President of the International Society of Nucleosides, Nucleotides & Nucleic Acids (2019-20) and the Oligonucleotide Therapeutics Society (2013-14).

Jeff Collerمشاهده پروفایل

استاد

• mRNA stability
• translation elongation
• RNA therapeutics
• +۳ مورد دیگر

Jeff Coller is the Bloomberg Distinguished Professor of RNA Biology and Therapeutics at Johns Hopkins University. His primary affiliation is with the Whiting School of Engineering and the Johns Hopkins School of Medicine, within the Department of Biomedical Engineering. He holds a PhD in Cellular and Molecular Biology from the University of Wisconsin and completed postdoctoral training at the Howard Hughes Medical Institute, University of Arizona. Previously, he was Director of the RNA Center at Case Western Reserve University and held the Henry Willson Payne Distinguished Professorship. Research Focus: Coller's lab investigates mRNA stability and translation, particularly how mRNA sequence features like codon optimality influence gene expression. His work bridges fundamental biology and translational medicine, with a focus on RNA-based therapies. He co-founded Tevard Biosciences and WyveRNA Therapeutics, which focus on RNA therapeutics. His research has been cited over 6,000 times and led to several patents in RNA-based therapies. Education: PhD in Cellular and Molecular Biology, University of Wisconsin; Postdoc at HHMI, University of Arizona Labs/Teams: Coller Lab (Johns Hopkins University) Grants/Funding: Not explicitly detailed, but implied via patent activity and industry partnerships Key Contributions: Demonstrated that mRNA sequence features directly influence stability and translation efficiency. Pioneered understanding of codon optimality's role in mRNA fate. Co-developed novel RNA-based therapeutics.

Anumantha Kanthasamyمشاهده پروفایل

دانشگاهی

• Neurodegenerative Diseases
• Parkinson's Disease (PD)
• Neurotoxicology
• +۷ مورد دیگر

Anumantha Kanthasamy is the Johnny Isakson Distinguished Professor and Director of the Isakson Center for Neurological Disease Research at the University of Georgia's College of Veterinary Medicine. He holds the Georgia Research Alliance Eminent Scholar title and leads a lab focused on neurodegenerative diseases, particularly Parkinson’s Disease (PD). His research integrates molecular mechanisms of neurotoxicity, protein aggregation, mitochondrial dysfunction, and translational biomarker development. Affiliations: Department of Physiology and Pharmacology, Isakson Center for Neurological Disease Research, University of Georgia Education: PhD in Biochemistry (University of Madras), Postdoctoral training in Pharmacology at Purdue University Research Interests include: neurotoxicant-induced dopaminergic degeneration, α-synuclein aggregation pathways, mitochondrial dysfunction in neurodegeneration, and development of biomarkers and therapies targeting PD. His work bridges basic science and clinical translation, including live-bacterial L-DOPA therapy and exosome-based diagnostics. Key Contributions include identifying PKCδ as a key mediator of oxidative stress-induced neuronal death, discovering manganese’s role in protein aggregation via prion protein interactions, and pioneering RT-QuIC-based detection of α-synuclein in skin and biofluids. Scientific Awards: Multiple NIH grants (NIEHS, NINDS), DoD funding, MJFF support, and recognition as an NAI Fellow. Advising & Grants: Trained over 30 PhD students, leads a 25-member lab, and has secured continuous federal funding for over two decades. Current projects include drug discovery targeting Kv1.3 and PKD1 pathways. Labs/Teams: Kanthasamy Lab at UGA, Isakson Center collaborations, and partnerships with industry for translational drug development.

• Chemical Biology
• Protein Lipidation
• Synthetic Biology
• +۳ مورد دیگر

Bryan Dickinson is a Professor in the Department of Chemistry at the University of Chicago. His research focuses on chemical biology approaches to protein lipidation , synthetic biology , and RNA engineering , with significant contributions to understanding S-acylation dynamics and developing programmable RNA effectors. Key research themes include: Protein-lipid interactions in metabolic diseases RNA-based synthetic biology tools for gene expression manipulation Epitranscriptomic regulation in neurological contexts Novel chemical probes for redox and stress signaling His recent publications (2025-2023) emphasize oxidative stress response , macrocyclic inhibitors , and synaptic RNA regulation . Funding from NIH (R13CA290754, R01EB035016, R01MH122142) supports work on therapeutic development and multidimensional protein interaction analysis. The Dickinson lab employs high-throughput selection systems , split polymerase biosensors , and live-cell imaging to study biochemical pathways in diabetes, neurodegeneration, and cancer.

Zenghuo Linمشاهده پروفایل

دانشیار

• Genomics
• Evolutionary Biology
• Molecular Biology
• +۵ مورد دیگر

Zenghuo Lin is an Associate Professor in the Department of Biology at Saint Louis University, part of the College of Arts and Sciences. His research focuses on the evolution of genomes and gene regulation in fungal models. Lin holds a Ph.D. from Pennsylvania State University. His lab, the Lin Lab (www.zlinlab.org), develops bioinformatics tools like TSSr for analyzing transcription start site (TSS) data. Key research themes include transcription initiation mechanisms, genome divergence post-hybridization, and functional impacts of 5'UTR length evolution. Notable recent work includes studies on ribosomal subunit modulation in cancer progression, yeast poly(A)-binding proteins, and the genomic origins of cultivated bananas. Lin collaborates widely, with funding from sources like the National Institutes of Health and NSF, and mentors over 30 graduate and undergraduate students. He teaches courses in genetics, genomics, and bioinformatics. Publications span high-impact journals like Genome Research, Nature Genetics, and Nature Protocols. Awards include recognition for contributions to fungal genomics. Lin advises on genomic projects ranging from Saccharomyces bayanus assembly to desert-adapted Drosophila genetics. His lab actively pursues systems-level approaches to RNA epitranscriptomics and epigenetic regulation, with future directions in synthetic biology applications of transcriptional control mechanisms.

• Bioinformatics
• Computational Genomics
• Transcriptional Regulation
• +۴ مورد دیگر

Zhiping Weng is a Professor and Chair of the Department of Genomics and Computational Biology at the University of Massachusetts Chan Medical School. She holds the Li Weibo Chair in Biomedical Research and is affiliated with the T.H. Chan School of Medicine and Morningside Graduate School of Biomedical Sciences. Her research focuses on computational biology, genomics, and systems biology, with a particular emphasis on understanding gene regulation, epigenomics, and small RNA biology. Dr. Weng earned her B.S. in Electrical Engineering from the University of Science and Technology of China (1992) and her Ph.D. in Biomedical Engineering from Boston University (1997). She joined UMass Chan Medical School in 2008 to establish the Program in Bioinformatics and Integrative Biology. Her research integrates computational methods with high-throughput genomics data to study transcriptional regulation, protein interactions, and small RNA mechanisms. Key projects include developing tools for predicting transcription factor binding sites, analyzing nucleosome positioning, and modeling protein complexes. Her lab also explores the role of piRNAs and miRNAs in transposon silencing and developmental processes. Recent work includes studies on tRNA sequencing, koala retrovirus evolution, and the functional annotation of regulatory elements across species. Her contributions span bioinformatics tool development (e.g., ZDOCK for protein docking) and collaborative efforts in genome-wide studies like ENCODE. Dr. Weng advises students and postdocs in computational biology and collaborates extensively on epigenetic and systems biology projects. Her lab is part of the broader genomic research community at UMass Chan, contributing to advancements in personalized medicine and functional genomics.

Sebastian Baumgartenمشاهده پروفایل

پژوهشگر

• RNA modifications
• Parasitology
• Malaria
• +۱۲ مورد دیگر

Sebastian Baumgarten is the Head of the 'Parasite RNA Biology' Group at the Institut Pasteur, France, a position he has held since June 2021. He is affiliated with the Department of Biology of Host-Parasite Interactions. Previously, he was a post-doctoral researcher at the same institute from 2016 to 2021. His educational background includes a Ph.D. (2013–2016) and MSc (2012–2013) from the Red Sea Research Center at King Abdullah University of Science and Technology, Saudi Arabia, and a BSc (2009–2012) from the University of Tübingen, Germany. His research centers on RNA biology in malaria parasites, particularly focusing on RNA modifications such as m6A and tRNA methylation, epigenetic regulation, and post-transcriptional gene control in Plasmodium falciparum . He employs advanced genomic techniques including CRISPR, RNAseq, and ChIPseq to study gene regulation and immune evasion mechanisms in protozoan parasites. His recent publications reveal a strong trend in understanding how RNA modifications influence parasite development, stress response, and antigenic variation. His work bridges molecular parasitology with epitranscriptomics, contributing significantly to the understanding of gene regulation in malaria parasites. Notable scientific contributions include studies published in Nature Microbiology , mBio , EMBO Reports , and Life Science Alliance , focusing on m6A methylation, RUF6 ncRNA interactions, and cohesin-mediated gene repression. He has supervised or collaborated with several researchers including post-doctoral fellows, PhD students, and technicians within his team. His group is actively involved in uncovering the molecular mechanisms of parasite survival and immune evasion, with potential implications for antimalarial drug and vaccine development. The 'Parasite RNA Biology' group operates within the Institut Pasteur's ecosystem, leveraging interdisciplinary platforms for genomics, imaging, and functional analysis to advance understanding of malaria parasite biology.

• Epigenetics
• Chromatin Modifications
• Histone Methylation
• +۶ مورد دیگر

Prof. Dr. Robert Schneider is the Director of the Institute of Functional Epigenetics at Helmholtz Munich and Professor at the Faculty of Biology of Ludwig-Maximilians-University Munich since 2016. His research focuses on epigenetics, chromatin dynamics, and the interplay between cellular metabolism and histone modifications to decode gene expression regulation and disease mechanisms. Education: Ph.D. from Ludwig-Maximilian University Munich; Postdoctoral research at the Gurdon Institute (University of Cambridge, UK). Robert’s work spans the study of histone methylation, epigenetic reprogramming, and environmentally triggered diseases. His lab also explores epitranscriptomics and epigenetic memory in single cells to identify novel therapeutic targets. His scientific contributions include leadership roles in international research schools like Epigenetics@HelmholtzMunich and the International Helmholtz-Edinburgh Research School for Epigenetics “EpiCrossBorders.” Scientific Awards: Elected Member of Academia Europeae (2021), HFSP and EMBO Fellow (2000-2004), HFSP Career Development Award (2005-2012), ERC Grantee, Chaire Gutenberg (2012). Robert is deeply committed to mentoring future scientists, co-founding the International Max Planck Research School (IMPRS-MCB) and leading the EpiCrossBorders training program for epigenetics research.

Harish Vashisthمشاهده پروفایل

استاد

• Computational Biophysics
• Chemical Physics
• Soft Matter and Self-assembly
• +۱۴ مورد دیگر

Harish Vashisth serves as Professor of Chemical Engineering & Bioengineering at the University of New Hampshire, where he teaches graduate courses including Advanced Chemical Engineering Thermodynamics and Computational Molecular Bioengineering. His research focuses on computational approaches to biomolecular problems with applications in therapeutic design and materials discovery. His educational background includes: Ph.D. in Chemical Engineering from Drexel University Bachelor of Technology in Chemical Engineering from National Institute of Technology Research Expertise: Dr. Vashisth specializes in Computational Biophysics, Chemical Physics, and Soft Matter Self-assembly. His laboratory employs molecular thermodynamics and statistical mechanics to investigate complex macromolecules including proteins, nucleic acids, and colloids. This work bridges fundamental biophysical principles with applications in drug design, biomaterials engineering, and artificial water channel development. Publication Trends: Analysis of 15 most recent publications (2023-2025) reveals dominant themes in viral peptide-receptor interactions, transmembrane domain dynamics, and light-responsive colloidal systems. His group consistently integrates molecular dynamics simulations with quantum chemistry methods, demonstrating strong interdisciplinary collaboration between computational and experimental approaches in biophysical chemistry. Scientific Recognition: No major awards or fellowships are documented in current profile Academic Leadership: Dr. Vashisth supervises doctoral research in chemical engineering and bioengineering, teaching core graduate courses while directing the Vashisth Research Group. His work has secured federal research funding for projects on biomolecular modeling and soft matter systems, particularly in biomimetic membrane development. Research Infrastructure: The Vashisth Research Group operates within UNH's Chemical Engineering & Bioengineering department, utilizing high-performance computing for molecular simulations. The lab collaborates extensively with experimental groups on projects involving artificial water channels, viral replication mechanisms, and novel biomaterials for Angstrom-scale separations.

Gary Brennanمشاهده پروفایل

استادیار

• Epigenetics
• RNA Biology
• Epilepsy
• +۲ مورد دیگر

Dr. Gary Brennan is an Assistant Professor at the School of Biomolecular and Biomedical Science, University College Dublin, and a member of the Conway Institute. He is a Funded Investigator at the FutureNeuro Research Center and has held affiliations with institutions including the Royal College of Surgeons in Ireland (RCSI) and the University of California-Irvine. His research focuses on the molecular mechanisms of epilepsy, particularly epigenetic and epitranscriptomic regulation, RNA modifications, and neuroinflammatory pathways. Education: PhD in Physiology & Medical Physics from RCSI (2015) Postdoctoral Training: University of California-Irvine (2012-2015) under Prof. Tallie Z. Baram; RCSI (2016-2018) under Prof. David Henshall His research program addresses three critical challenges: (1) understanding molecular reprogramming after brain insults, (2) developing RNA-based therapies targeting epigenetic processes, and (3) identifying peripheral biomarkers for epilepsy prediction. Key contributions include studies on microRNA regulation of seizure networks, m6A RNA methylation in temporal lobe epilepsy, and systemic delivery of antagomirs timed with blood-brain barrier disruption. His work has been published in journals like Nature Reviews Neurology , JCI Insight , and Molecular Brain . Recent funding includes grants from Science Foundation Ireland (SFI), Health Research Board (HRB), and the European Union. He has received awards such as the CURE Taking Flight Award and Marie Curie Fellowship. Dr. Brennan also supervises PhD students and coordinates modules on CNS diseases and multicellular systems.

Sara Silva Pereiraمشاهده پروفایل

استادیار

• Parasitology
• Immunology
• Microbiology
• +۶ مورد دیگر

Sara Silva Pereira is an Assistant Professor at the Católica Medical School , focusing on African trypanosomes and their interactions with mammalian hosts. Her lab combines computational biology, infection biology, and tissue bioengineering to model disease environments and develop therapeutic strategies. Education : PhD in Veterinary Parasitology, University of Liverpool (2018) BSc in Biomedical Sciences with minor in Biochemistry, King's College London (2014) Research Interests : Antigenic diversity and evolutionary biology of African trypanosomes Bioengineered vascular models to study parasite sequestration Molecular mechanisms of immune evasion and infection dynamics AI applications in parasitology and disease surveillance Scientific Awards : L'Oréal Portugal Medal of Honor for Women in Science (2024) Prémio Maria de Sousa (2022) Research Trends : Her recent work spans parasitology , bioengineering , and AI-driven diagnostics , with emphasis on Trypanosoma congolense , Trypanosoma vivax , and Vascular Endothelium interactions. Grants and Collaborations : Funded by La Caixa Foundation, European Commission, EMBO, and Fundação BIAL. Collaborates with institutions in the UK (University of Glasgow, Earlham Institute), Spain, Brazil, Kenya, and South Africa.

Pavlina Gregorovaمشاهده پروفایل

پژوهشگر

• Biochemistry, cell and molecular biology
• Biomedicine
• Microbiology and virology

Pavlina Gregorova is a Doctoral Researcher at the University of Helsinki , affiliated with the Faculty of Biological and Environmental Sciences and the Molecular and Integrative Biosciences Research Programme . Her work bridges biochemistry, molecular biology, and microbiology. Biochemistry, cell and molecular biology Biomedicine Microbiology and virology Research Interests focus on post-transcriptional RNA modifications, particularly their role in translation regulation and infection dynamics. Recent studies explore tRNA cleavage in extremophiles, RNA modifications in prostate cancer, and aging-related protein structural changes. Scientific Contributions include developing novel methods for RNA virus quantification, analyzing RNA modification landscapes, and characterizing enzyme-polymerization-based longevity controls. Her work spans Microorganisms , Nucleic Acids Research , and Molecular Cell . Fulbright Finland Foundation Travel Grant for Research Collaboration (2020) She actively supervises Master's theses and participates in international collaborations, including a research visit at Johns Hopkins University . Gregorova contributes to organizations like the RNA Society and Societas biochemica, biophysica et microbiologica Fenniae .

• Neurogenomics
• Human Genetics
• Autism Spectrum Disorders
• +۷ مورد دیگر

Daniel Geschwind, M.D., Ph.D., is the Gordon and Virginia MacDonald Distinguished Chair in Human Genetics and Professor of Neurology and Psychiatry & Biobehavioral Sciences at the University of California, Los Angeles (UCLA). He serves as the founding Director of the Center for Autism Research and Treatment (CART) and Co-Director of the Center for Neurobehavioral Genetics, with additional appointments in the Tennenbaum Center for the Biology of Creativity, the Brain Research Institute, and multiple Graduate Ph.D. Program Home Areas (Bioinformatics, Neuroscience, Medical Informatics, Genetics & Genomics, Workforce Development). Education & Training: While specific degree-granting institutions are not listed in the provided text, Dr Geschwind holds both M.D. and Ph.D. degrees and completed clinical and research training that led to board certification in neurology and human genetics. Research Focus: Geschwind’s laboratory integrates large-scale human genetics, functional genomics, single-cell transcriptomics, and systems biology to understand the genetic architecture of neurodevelopmental and neurodegenerative diseases. Major themes include: Autism spectrum disorders and related neurodevelopmental conditions Frontotemporal dementia, progressive supranuclear palsy, and Alzheimer disease Gene-regulatory networks controlling neuronal identity and synaptic function Multi-omics biomarker discovery for early diagnosis and therapeutic targeting Grant Support & Leadership: He has served as Principal Investigator on numerous NIH MERIT, Autism Centers of Excellence, and foundation awards, including the Paul G. Allen Foundation Distinguished Investigator Award. His leadership roles span the UCLA ATLAS Community Health Initiative, international genetics consortia (e.g., ALLFTD, iPSYCH, PsychENCODE), and advisory boards for the National Academy of Medicine. Scientific Awards: 2022 Rhoda & Bernard Sarnat International Prize in Mental Health, National Academy of Medicine 2022 Cotzias Lecture & Award, American Academy of Neurology 2021 Gold Medal, Society of Biological Psychiatry 2015 Paul G. Allen Foundation Distinguished Investigator Award 2006–2015 NIMH MERIT Award Election to the National Academy of Medicine and American Academy of Physicians Laboratory & Teams: The Geschwind Laboratory is housed at 695 Charles E Young Drive South, Los Angeles, CA 90095. The group comprises post-doctoral fellows, graduate students, computational biologists, and clinical research coordinators working at the intersection of genomics, neuroscience, and precision medicine.

• Molecular Cell Biology
• Signal Transduction
• Gene Expression Regulation
• +۵ مورد دیگر

Shim Jae-kyung serves as Assistant Professor in the Department of Bioindustry and Resource Engineering at Sejong University's School of Life Systems, where she has conducted research since 2015 following her prior appointment in the Department of Molecular Biology (2003-2014). Her work centers on nuclear signaling mechanisms and disease pathogenesis. Her academic foundation includes: Ph.D. in Biological Science from Korea Advanced Institute of Science and Technology (2000) M.S. in Biochemistry from Yonsei University (1994) B.S. in Biochemistry from Yonsei University (1991) Research focuses on nuclear signal transduction and gene expression regulation , particularly examining Notch/STAT3 pathway crosstalk , nuclear membrane protein functions (Emerin), and RNA modification mechanisms (YTHDF2). Her laboratory employs zebrafish developmental models , mammalian cell systems , and plant stress response studies to investigate disease mechanisms including cancer progression and developmental disorders. Current work reveals how spatial control of signaling molecules at the nuclear membrane regulates transcriptional outcomes. Publication analysis shows consistent emphasis on nuclear signaling hubs since 2014, with recent work (2021-2024) demonstrating triptolide's dual regulation of Notch/STAT3 in cancer and development, Emerin's spatial control of STAT3, and YTHDF2's post-transcriptional regulation of Notch. Plant research complements this through stress response mechanisms in crops. Professor Shim leads the Molecular and Cellular Biology Laboratory (Chung1127), supervising master's thesis research while teaching courses including General Biochemistry, Biopolymer Engineering, and Antibody Engineering. Her consultation hours are Monday, Wednesday, and Friday 3:00-5:00 PM.