Bryan Dickinson

Bryan Dickinson is a Professor in the Department of Chemistry at the University of Chicago. His research focuses on chemical biology approaches to protein lipidation, synthetic biology, and RNA engineering, with significant contributions to understanding S-acylation dynamics and developing programmable RNA effectors.

Key research themes include:

• Protein-lipid interactions in metabolic diseases
• RNA-based synthetic biology tools for gene expression manipulation
• Epitranscriptomic regulation in neurological contexts
• Novel chemical probes for redox and stress signaling

His recent publications (2025-2023) emphasize oxidative stress response, macrocyclic inhibitors, and synaptic RNA regulation. Funding from NIH (R13CA290754, R01EB035016, R01MH122142) supports work on therapeutic development and multidimensional protein interaction analysis.

The Dickinson lab employs high-throughput selection systems, split polymerase biosensors, and live-cell imaging to study biochemical pathways in diabetes, neurodegeneration, and cancer.