جست‌وجوی استاد و پژوهشگر

• -omics technologies
• structural bioinformatics
• molecular modeling of transmembrane proteins
• +۳ مورد دیگر

Pawel Herzyk is an Honorary Senior Lecturer at the School of Molecular Biosciences , University of Glasgow. His work spans bioinformatics, structural biology, and stress response mechanisms in plants and biomedical systems. Education/Background : Not explicitly detailed in the provided text. Research Interests : Focused on -omics data analysis, structural bioinformatics, and molecular modeling of transmembrane proteins. Key themes include plant stress adaptation, epigenetic regulation, and gene expression dynamics in both model organisms and disease contexts. Article Trends : His publications highlight interdisciplinary approaches, merging computational biology with experimental validation in plant and human systems. Topics range from chromatin-level transcriptional control in Arabidopsis to metabolic adaptations in leukemia and neurodegenerative diseases. Labs/Teams : Collaborates with multidisciplinary groups in Glasgow Polyomics , Plant Molecular Biology , and Biomaterials Research , often linking bioinformatics with experimental models.

• Gene Regulation
• Haematology
• Genetic Disorders
• +۳ مورد دیگر

Siyu Liu is a Research Fellow at the MRC Molecular Haematology Unit , University of Oxford. Her work focuses on understanding the molecular mechanisms underlying α-thalassaemia, specifically the regulation and potential reactivation of the embryonic ζ-globin gene to mitigate severe symptoms like Hb Barts’ Hydrops Fetalis Syndrome. With a DPhil (Doctor of Philosophy), her research intersects gene regulation , haemoglobinopathy , and genetic disorders , aiming to uncover how adjacent enhancers influence gene silencing in adult erythroblasts despite proximity to active regions. This has broader implications for therapeutic strategies in inherited blood diseases. Her studies are supported by the MRC Translational Immune Discovery Unit and Centre for Computational Biology , though no specific grants or awards are documented in the provided text. Siyu Liu’s contributions highlight the importance of epigenetic and enhancer dynamics in haematological research.

Chris Maloneyمشاهده پروفایل

استاد

• Nutrition
• Obesity
• Diabetes
• +۵ مورد دیگر

Dr. Chris Maloney is a researcher at the School of Health Sciences within UNSW Medicine, The University of New South Wales, specializing in the intersection of nutrition, obesity, and epigenetics. His work focuses on understanding how parental obesity can program offspring for metabolic diseases across generations. Dr. Maloney holds a BMed Sci (Hons 1) and PhD from the University of Sydney. His research centers on the 'fetal programming of adult diseases,' particularly Obesity and Diabetes, with increasing emphasis on paternal obesity and its transgenerational epigenetic consequences. He investigates how micronutrient supplementation might prevent the transmission of obesity effects from parents to offspring. His methodological approach examines DNA methylation as a key mechanism for permanent alterations in gene expression that affect metabolism. Dr. Maloney's work bridges basic epigenetic science with potential nutritional interventions that could mitigate the global obesity epidemic. Dr. Maloney serves as Editor for The Journal of Nutrition Science (2018-current) and previously for The British Journal of Nutrition (2015-2021). His professional affiliations include The Nutrition Society (2015-current), The Australian and New Zealand Obesity Society (Council member, 2009-2015), and The Nutrition Society of Australia (2009-2021). His publication record includes 1 book, 34 journal articles, 6 conference papers, 7 conference posters, 5 conference presentations, and 6 conference abstracts, demonstrating his significant contribution to understanding transgenerational epigenetic inheritance related to obesity and metabolic health.

Mirre Simonsمشاهده پروفایل

پژوهشگر ارشد

• Evolutionary Biology
• Aging Research
• Senescence
• +۷ مورد دیگر

Dr. Mirre Simons is a Sir Henry Dale Senior Fellow at the School of Biosciences, University of Sheffield. She leads a research group focused on evolutionary and mechanistic aspects of aging, with emphasis on dietary restriction and mortality patterns. Her work bridges fundamental evolutionary questions with translational applications in aging research. Dr. Simons received her PhD cum laude from the University of Groningen in 2013, following an MSc Research degree in 2008. Her academic journey includes a NERC-funded postdoctoral position at Sheffield (2013-2015), Sir Henry Wellcome Fellowship (2015-2019), Vice-Chancellor's Fellowship (2015-2019), and currently the prestigious Sir Henry Dale Senior Fellowship (2019-2025). Her research investigates the adaptive value of differences in aging between and within species. Key areas include: Demography of mortality and lifespan patterns Dietary restriction mechanisms and effects on aging Costs of reproduction and evolutionary trade-offs Biology of cancer and cellular senescence Telomere length dynamics Dr. Simons' recent publications reveal a strong focus on using Drosophila to study dietary restriction mechanisms, combining evolutionary biology with molecular approaches. A notable trend is her investigation into how dietary interventions can rapidly reduce mortality risk (within 1-2 days), with potential translational applications for healthspan extension. Her major scientific recognitions include: Sir Henry Dale Fellowship, Wellcome & Royal Society (2019-2025) Vice-Chancellor's Fellowship, Sheffield (2015-2019) Sir Henry Wellcome Fellowship (2015-2019) Dr. Simons actively mentors PhD students Sarah Gautrey, Alex Charles, and Katie Roome, as well as undergraduate and master's students. Her research is supported by prestigious fellowships from Wellcome, the Royal Society, and Sheffield. She teaches APS359 Topics in Modern Zoology and supervises various student projects. Her laboratory investigates why and how all life deteriorates to cause death. The lab takes a holistic approach to aging, studying both evolutionary perspectives and molecular mechanisms. They focus particularly on diet-aging connections, with the notable finding that dietary protein reduction in flies rapidly reduces mortality risk 6-7 fold. The lab uses functional genetics with potential translational applications for healthspan extension.

Davide Michielettoمشاهده پروفایل

پژوهشگر ارشد

• Topological Soft Matter
• Polymer Physics
• Biophysics
• +۶ مورد دیگر

Davide Michieletto is a Research Fellow at the University of Edinburgh , affiliated with the Institute of Genetics and Molecular Medicine (IGMM). His work focuses on topological problems in soft matter and biology , particularly DNA topology, genome organization, and DNA-based soft materials. Education: BSc and MSc in Physics (University of Padova, Italy), PhD in Physics and Complexity Science (University of Warwick, UK) Awards: 2024 Leverhulme Prize in Physics, 2024 Louise Johnson Early Career Award, 2021 RSC Early Career Award, 2020 Royal Society University Research Fellowship, 2019 Leverhulme Early Career Fellowship, 2015 Ian Macmillan Ward Prize The TAPLab (Topologically Active Polymers) explores how topological and mechanical control of DNA can inspire new smart materials. Recent work includes: Machine learning approaches to identify knots in polymers (Physics World 2024) DNA nanostar gels with tunable elasticity (Nature Materials 2025) Topological analysis of kinetoplast DNA (NAR 2025) DNA origami rheology studies (Soft Matter 2024) His research bridges polymer physics , biophysics , and machine learning to address fundamental questions in genome organization and material science. Key publications span non-equilibrium dynamics , viscoelastic condensates , and DNA topology in extreme conditions. Scientific Awards include: 2024: Leverhulme Prize in Physics 2024: Louise Johnson Early Career Award (British Biophysical Society) 2021: Early Career Award in Statistical Mechanics (Royal Society of Chemistry) 2020: Chancellor's Rising Star Award (Edinburgh) As an adviser , Davide mentors PhD students like Giorgia Palombo (hybrid DNA hydrogels), Yair Fosado (multi-scale DNA modeling), and Djordje Mihajlovic (machine learning for knots). He supports funding opportunities including Wellcome Trust , Marie Sklodowska-Curie , and ERC Starting Grants . The TAPLab team includes postdocs (Cleis Battaglia, Simon Weir, Yair Fosado, Saminathan Ramakrishnan), PhD students (Amandine Hong-Minh, Giorgia Palombo, Jenny Harnett, Dinesh Parthasarathy, Djordje Mihajlovic, Filippo Conforto, Emma Tomlinson), and SOFI PhD candidates (Ella Sapsford, Jenny Harnett). Recent work involves collaborations with IGMM and ESRIC for high-resolution AFM imaging.

Szymon Drobniakمشاهده پروفایل

مدرس ارشد

• Evolutionary Biology
• Ecology
• Animal Coloration
• +۶ مورد دیگر

Szymon Drobniak is an Adjunct Senior Lecturer at the School of Biological, Earth & Environmental Sciences at the University of New South Wales (UNSW) and an Associate Professor at Jagiellonian University in Poland. His career spans roles as a Research Assistant (2012–2015) and Postdoctoral Fellow at the University of Zurich (2013–2015) and Uppsala University (2017–2018). He was awarded a DECRA Fellowship at UNSW in 2019. PhD in Biology (Jagiellonian University, 2012) MSc in Mathematical and Natural Sciences (Jagiellonian University, 2008) Research Interests: Drobniak specializes in meta-analysis and comparative ecology, focusing on animal coloration (particularly avian plumage), phenotypic plasticity, quantitative genetics, and the ecological consequences of climate change. His work often integrates statistical ecology, thermal biology, and evolutionary genetics. Article Trends: His recent publications emphasize methodological rigor in ecological meta-analyses, thermal tolerance in ectotherms, and the role of non-genetic inheritance. He frequently collaborates on interdisciplinary projects, including the SPI-Birds data hub and Co-BreeD database. Keywords cluster around Evolutionary Biology , Ecology , and Statistics , with subfields like Thermal Acclimation , Avian Reproduction , and Scientific Transparency . Scientific Awards: Winner of FameLab 2015 in Poland Outreach & Collaborations: Drobniak is a prolific science communicator, authoring two popular science books and hosting TV shows. He collaborates with institutions like the Museum of Modern Art in Kraków and contributes to initiatives like the EuroScitizen COST Action. His work bridges empirical research and policy, advocating for open science and inclusivity in academic publishing.

Ozren Bogdanovicمشاهده پروفایل

دانشیار مدعو

• Epigenomics
• Developmental Biology
• Molecular Biology
• +۴ مورد دیگر

Ozren Bogdanovic is an Adjunct Associate Professor at the University of New South Wales and a Lab Head at the Garvan Institute of Medical Research. He obtained his PhD in Molecular Biology from Radboud University (Netherlands) and conducted postdoctoral work at the University of Western Australia. Research Focus: Epigenomics, DNA methylation, and their roles in vertebrate embryogenesis and cancer. Key Contributions: Discovery of conserved epigenome remodeling in vertebrate development and studies on non-CpG methylation in zebrafish and lamprey. Recent Trends: 2025 work includes genome assembly techniques and DNA methylation readers in plants. Earlier studies (2024–2022) explore tumor biomechanics, dingo genomics, and epigenetic dynamics in cancer and development. Scientific Awards: 2017 Millennium Science Award 2017 Raine Research Prize 2013 ARC DECRA 2013 EMBO Travel Grant Multiple UWA and collaborative awards Collaborations: Work with labs in Spain, Australia, and international teams on developmental genetics and epigenetic inheritance. Lab activities include integrative approaches to embryonic gene regulation and cancer methylome analysis.

• Epigenetics
• Chromatin Biology
• Molecular Biology
• +۷ مورد دیگر

Robert E. Kingston serves as Chief Academic Officer at Massachusetts General Hospital , affiliated with Harvard Medical School and the Department of Molecular Biology . His research focuses on epigenetic regulation , chromatin remodeling , and transcriptional control mechanisms . Key research themes include Polycomb group proteins, non-coding RNA interactions, and histone variant dynamics. His work bridges developmental biology and cancer epigenetics , particularly in leukemia aggressiveness and stem cell fate. Publication Trends : Recent studies explore chromatin condensate formation , nuclear autophagy , and genomic accessibility changes . 2025 work highlights inflammation regulation , while 2024 articles focus on clonal evolution in cancer and nucleosome compaction .

Eva Jablonkaمشاهده پروفایل

استاد

• Non-genetic hereditary variations
• Evolution of nervous systems
• Evolution of consciousness
• +۳ مورد دیگر

Eva Jablonka is a Professor at Tel-Aviv University, affiliated with the Cohn Institute for the History and Philosophy of Science and Ideas and a member of the Sagol School for Brain Research . Her research focuses on evolutionary mechanisms beyond genetic inheritance, including the evolution of nervous systems and consciousness. Education: M.Sc. in Microbiology (Ben-Gurion University), Ph.D. in Genetics (Hebrew University, Jerusalem) Postdoctoral studies in Philosophy of Science and Developmental Genetics Her work bridges epigenetics, evolutionary biology, and cultural evolution, emphasizing non-genetic hereditary variations. She contributes to understanding how these mechanisms shape biological and cognitive complexity. Network: Health Inequality (HI) Discipline: Life sciences

Isabelle Mansuyمشاهده پروفایل

استاد

• Neuroepigenetics
• Epigenetic inheritance
• Molecular psychiatry
• +۵ مورد دیگر

Isabelle Mansuy is Full Professor of Neuroepigenetics at the Department of Health Sciences and Technology at ETH Zurich and holds a dual appointment at the Brain Research Institute of the Medical Faculty of the University of Zurich. She serves as Deputy Head of the Institute for Neuroscience at ETH Zurich and Co-Director of both the Brain Research Institute (UZH) and Institute for Neuroscience (ETHZ). Her educational background includes: Degrees in Biotechnology Engineering and Molecular Biology from Université Louis Pasteur and École Supérieure de Biotechnologie de Strasbourg European PhD in Molecular and Developmental Neurobiology from Université Louis Pasteur (1994) Postdoctoral training at Columbia University's Center for Neurobiology and Behavior with Eric Kandel Mansuy's research focuses on the epigenetic basis of complex brain functions and the transgenerational transmission of acquired behaviors in mammals. Her laboratory employs a multidisciplinary approach combining epigenetic and genetic methods, behavioral testing, multi-omics techniques, bioinformatics, and imaging. Key research areas include: Epigenetic inheritance of trauma-induced traits across generations Neuroepigenetic mechanisms of memory formation and forgetting Chromatin organization in brain and germ cells Early life stress effects on mental and physical health Development of potential diagnostic and therapeutic tools for trauma patients Analysis of her recent publications reveals a strong focus on transgenerational epigenetic inheritance, particularly examining how early life stress affects germ cells and leads to behavioral and physiological changes across multiple generations. Her work increasingly incorporates multi-omics approaches to identify molecular signatures of trauma in both animal models and human subjects. Her scientific honors include: Election to the European Academy of Sciences (2017) Knight in the Order of the Legion of Honour, France (2016) Membership in the Research Council of the Swiss National Science Foundation (2011) EMBO membership (2006) Multiple prestigious research awards including the Robert Bing Prize (2008) Mansuy has supervised numerous PhD students and postdoctoral fellows, contributing significantly to training the next generation of neuroscientists. Her research has been supported by major funding agencies including the Swiss National Science Foundation. She leads an active laboratory with multiple ongoing projects exploring different aspects of epigenetic memory and inheritance, including epigenetic memory in the germline, soma-to-germline communication, and the impact of stress on chromatin organization. The Mansuy Lab maintains strong collaborations with clinicians to translate findings from mouse models to human trauma patients, particularly focusing on childhood trauma effects. The lab also collaborates with the Mateescu Group, which specializes in RNA biology and extracellular RNA research.

• Neural development
• Retinal degeneration and regeneration
• Neuroprotection mechanisms
• +۸ مورد دیگر

Dr. Xian-Jie Yang is a Professor in the Department of Ophthalmology at the University of California Los Angeles (UCLA) School of Medicine. Holding the Ernest G. Herman Chair (2012) and a 2022 Undergraduate Mentor Award, Yang's research focuses on molecular mechanisms governing retinal development, degeneration, and regeneration. Education: BS in Biology, Peking Normal University (1981) PhD in Biochemistry, Cell and Molecular Biology, Cornell University (1988) Postdoc in Developmental Biology, Harvard University (1989) Postdoc in Molecular Neuroscience, Harvard Medical School (1995) Yang's lab investigates retinal metabolism during development and disease, utilizing genetically engineered mice , viral vector gene delivery , and 3D retinal organoid cultures from human pluripotent stem cells. Current work funded by the California Institute for Regenerative Medicine (CIRM) aims to develop gene therapies for dominant optic atrophy. Recent publications highlight trends in neuroprotection mechanisms , stem cell applications , and transcriptional regulation in retinal biology. Yang's team has pioneered methods for enhancing retinal ganglion cell production and creating iPSC-based disease models . Key Awards: Helen Hay Whitney Foundation Fellowship (1988-1991) NIH Postdoctoral Fellowship (1992) Foundation Fighting Blindness Career Award (1996) Dolly Green Special Scholar Award (2003) Ernest G. Herman Chair (2012) Undergraduate Mentor Award (2022) Yang's work bridges molecular neuroscience and regenerative medicine , with NIH and CIRM funding supporting studies on signaling pathways affecting retinal neuron survival and gene editing approaches for inherited eye diseases.

Wanqiu Chenمشاهده پروفایل

استادیار

• Genomics
• Bioinformatics
• Microbiology
• +۴ مورد دیگر

Wanqiu Chen, PhD is an Assistant Research Professor in the Microbiology Division of the Basic Sciences department at Loma Linda University School of Medicine. Dr. Chen earned their PhD from Loma Linda University in 2009 and has established a productive research program focused on genomics, bioinformatics, and epigenetics. Dr. Chen's research interests span several key areas: Genomic analysis of cancer mechanisms and disease pathways Development and benchmarking of next-generation sequencing technologies Epigenetic changes related to environmental exposures Single-cell RNA sequencing methodologies and applications Computational approaches to drug discovery and molecular modeling Dr. Chen's publication record shows consistent output of high-impact research with over 60 publications spanning from 2007 to 2025. Their work often involves large collaborative efforts, particularly through the FDA Sequencing Quality Control Consortium II project, where they have contributed to multiple benchmarking studies of genomic technologies that have set standards in the field. Dr. Chen has received research funding for projects including: Genomic and Epigenomic Mechanisms of Maternal E-Cigarette induced Abnormal Brain Development (Co-Investigator) Investigating the genetic mechanisms of heritable connective tissue disorders Whole-genome and whole-methylome sequencing of the COVID-19 virus from patient samples Vertical transmission of COVID-19 infection during pregnancy Dr. Chen's laboratory work focuses on next-generation sequencing technologies, single-cell analysis, and bioinformatics approaches to understand disease mechanisms and develop better diagnostic and therapeutic strategies, with expertise spanning from raw data generation through computational analysis.

Zhong Chenمشاهده پروفایل

استادیار

• Genomics
• Epigenetics
• Bioinformatics
• +۷ مورد دیگر

Zhong Chen, PhD, is an Assistant Research Professor in the Microbiology Division of the School of Medicine at Loma Linda University. He joined the university in 2017 as a Research Associate and was promoted to his current rank in 2022. His expertise lies in genomics, epigenetics, and next-generation sequencing (NGS) technologies, with a focus on single-cell analysis, spatial omics, and bioinformatics. Research Focus: Dr. Chen's work spans multiple disciplines, including: Single-cell and spatial transcriptomics DNA methylation and epigenetic reprogramming Cancer genomics and mutation detection Transgenerational epigenetic inheritance COVID-19 genomics and virology Environmental toxicology and health disparities He has contributed to high-profile projects such as the FDA Sequencing Quality Control Consortium II and NIH-funded studies on maternal e-cigarette exposure and brain development. His research has been published in leading journals including Nature Biotechnology , Genome Biology , iScience , and Scientific Reports . Grants and Collaborations: Dr. Chen serves as Co-Investigator on an NIH-funded project on maternal e-cigarette exposure and brain development (2023–2028). He has also led or contributed to internal and external grants on genetic disorders, COVID-19 genomics, and dietary interventions. He is a key member of the LLU Center for Genomics, where he oversees raw data generation and quality control for NGS workflows, ensuring high standards in sequencing and analysis.

Anna Klocمشاهده پروفایل

دانشیار

• Heart disease
• Myocarditis
• Viral replication
• +۳ مورد دیگر

Anna Kloc is an Associate Professor in the Department of Biology and Environmental Science at the University of New Haven's College of Arts and Sciences. She holds a Ph.D. in Genetics from Stony Brook University and a B.A. in Biology from Hunter College, with post-doctoral training at the USDA-Plum Island Animal Disease Center and Yale University School of Medicine. Ph.D., Genetics, Stony Brook University B.A., Biology, Hunter College Her research focuses on the intersection of heart disease, viral replication, and immune system responses, particularly investigating how viral infections like Parvovirus B19 and Coxsackievirus B3 contribute to myocarditis. She combines molecular biology and virology techniques to analyze gene expression patterns in infected heart tissue and identify viral mutations that affect pathogenicity. The majority of her publications center on foot-and-mouth disease virus (FMDV), including studies on viral replication fidelity, untranslated regions, host protein interactions (e.g., Sam68, ADNP), and immune evasion mechanisms. These works contribute to broader trends in virology and molecular biology, with implications for antiviral drug development and vaccine design. Her laboratory employs sequencing methods to explore viral genome modifications and their impact on host-pathogen dynamics. She also contributes to health policy discussions as a University Health Policies spokesperson, emphasizing preparedness for communicable diseases.

Michael D. Coleمشاهده پروفایل

استاد

• genetic mechanisms of cancer
• oncogenic transcription factors
• gene regulation
• +۴ مورد دیگر

Michael D. Cole is a Professor of Molecular and Systems Biology at the Geisel School of Medicine, Dartmouth College. He leads a research laboratory focused on the genetic events driving cancer development and the molecular basis of diseases, particularly through the lens of eukaryotic gene regulation. His work spans decades, including pioneering studies on the chromosomal translocation between c-myc and the immunoglobulin locus in 1982. Research Interests: The Cole Lab investigates oncogenic transformation linked to transcription factor families Myc and E2F, emphasizing their role in misregulated gene networks in human cancers. Key research areas include chromatin architecture, distal regulatory elements, epigenetic mechanisms, mRNA cap methylation, and inherited cancer risk. Projects involve CRISPR-based gene editing, allelic expression analysis, and chromatin conformation studies. Laboratory Members: Current Graduate Students: Dustin Elwood, Edmond Feris, Elizabeth Sergison, Jillian Langer, Nadia Cumbal, Valeriya Posternak Former Students: Mandeep Kaur (PhD thesis on c-Myc gene repression via PRC2), Scott Turner (studying oncogene transcriptional dynamics) Publications: The lab has contributed extensively to cancer genetics, though specific titles are not listed here. Research trends focus on chromatin looping, enhancer function, and the interplay between genetic mutations and transcriptional networks.