DREADDs Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۴۲ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Justin Englishمشاهده پروفایل

استادیار

University of UtahUnited States

Justin English serves as Assistant Professor of Biochemistry at the University of Utah School of Medicine, where he develops molecular tools to investigate human health and disease mechanisms through directed evolution and protein engineering approaches. Education: B.A. from Cornell University Ph.D. from University of North Carolina at Chapel Hill Research Focus: Dr. English's laboratory specializes in Directed Evolution and Protein Engineering to create molecular tools for studying G-protein Coupled Receptors (GPCRs) , cell signaling pathways , and neuroscience applications . His work integrates synthetic biology with classical pharmacology to develop innovative platforms like VEGAS for mammalian cell evolution and TRUPATH for GPCR transducerome analysis, with significant implications for drug discovery and therapeutic development. Publication Trends: Analysis of his 2019-2025 publications reveals consistent focus on GPCR biology, featuring breakthroughs in biosensor development (nanobody-based receptor monitoring), chemogenetic tools (BioTAC system), and high-throughput screening platforms. His research demonstrates strong translational potential in neuroscience, particularly through engineered mouse models for psychedelic drug studies and molecular tools for mapping small-molecule interactomes. Research Environment: Dr. English leads an active laboratory within the University of Utah's Department of Biochemistry, leveraging institutional core facilities for biochemical and molecular studies. His research program maintains strong collaborative ties with neuroscience and pharmacology groups, with ongoing projects focused on advancing molecular engineering techniques for biomedical applications as detailed on his lab website.

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Christopher Priceمشاهده پروفایل

دانشیار

University of DelawareUnited States

Christopher Price is an Associate Professor at the Ammon Pinizzotto Biopharmaceutical Innovation Center, University of Delaware. His research focuses on musculoskeletal biomechanics, bone adaptation, and cartilage degeneration, with a particular emphasis on mechanotransduction and fluid flow dynamics in tissues. He holds a Ph.D. in Biomedical Sciences from Mount Sinai School of Medicine (2008) and a B.Sc. in Biomedical Engineering from Boston University (2000). Dr. Price’s research interests include the role of load-induced fluid flow in bone and cartilage health, advanced bioimaging techniques, and the development of disease-modifying therapies for osteoporosis and osteoarthritis. His work has received national/international recognition, including the Orthopaedics Research Society’s New Investigator Recognition Award (2010) and multiple Young Investigator Awards (2009–2010). Research focuses on mechanobiology, mechanosensory pathways, and tissue adaptation in musculoskeletal systems. Key areas: post-traumatic osteoarthritis, cartilage lubrication, and aging-related bone fragility. Utilizes cross-disciplinary methods: biomechanics, imaging, cell biology, and animal models. Publications span topics like solute transport in bone, cartilage tribology, and genetic influences on bone healing. His lab explores translational applications of mechanotransduction research to develop therapies targeting musculoskeletal diseases.

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Cynthia F. Mossمشاهده پروفایل

استاد

Johns Hopkins UniversityUnited States

Cynthia F. Moss is a Professor in the Department of Psychological and Brain Sciences at Johns Hopkins University (JHU), with joint appointments in Neuroscience and Mechanical Engineering. She directs the Comparative Neural Systems and Behavior Laboratory (Bat Lab), investigating neural mechanisms of sensory perception and spatial navigation in echolocating bats. Her work combines neurophysiology, behavioral ecology, and engineering to study how bats process auditory information for navigation, communication, and obstacle avoidance. Dr. Moss earned a B.S. (summa cum laude) from the University of Massachusetts, Amherst, and a Ph.D. from Brown University. She held prior faculty positions at Harvard University and the University of Maryland, where she directed the Neuroscience and Cognitive Science graduate program. Her research has received prestigious awards including the Hartmann Award (2017), James McKeen Cattell Award (2018), and Alexander von Humboldt Research Prize (2019). Her research focuses on sensory coding of natural stimuli, spatial perception, attention, and adaptive motor control. Key findings include discoveries about 3D auditory space representation in the midbrain, age-resistant hearing in bats, and the role of wing hairs in flight control. Her lab employs innovative techniques like wireless neural recording, two-photon imaging, and DREADDs-mediated inactivation to study neural circuits. Dr. Moss collaborates across disciplines, bridging neurobiology, robotics, and sensory systems engineering. Her work informs biomimetic technologies for sonar navigation and adaptive control systems. She actively mentors students and postdocs in the Krieger School of Arts and Sciences, Whiting School of Engineering, and School of Medicine at JHU.

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Laura Humphrysمشاهده پروفایل

پژوهشگر ارشد

Monash UniversityAustralia

Dr. Laura Humphrys is a Research Fellow in Drug Discovery Biology at the Monash Institute of Pharmaceutical Sciences, Monash University. Previously, she held a postdoctoral position at the University of Regensburg, Germany (2019–2022), focusing on peptide-based medicinal chemistry and CRISPR gene editing. She earned her PhD in Neuropharmacology from the University of Nottingham (2015–2020) and an MSci in Neuroscience from the same institution (2011–2015), with a year spent at the University of Melbourne. Education: PhD in Neuropharmacology, University of Nottingham (2015–2020) MSci in Neuroscience, University of Nottingham (2011–2015) Research Interests: Her work centers on visualizing and genetically modifying cell receptors in physiologically relevant cells. Key areas include GPCR biology, molecular biology, CRISPR technology, and drug discovery. She contributes to UN Sustainable Development Goals through advancements in therapeutic target identification. Key Contributions: Laura has published extensively on topics like histamine receptor pharmacology, fluorescent ligand development, and biased agonism in GPCRs. Her research bridges basic science and translational medicine, with a focus on understudied receptors. Awards: British Pharmacological Society Fellow (2023) AJ Clark Studentship (2015) Nottingham UNICAS Grant (2017) Activities & Collaboration: She actively participates in academic events, including the ASCEPT Drug Discovery Symposium (2024) and the 4GPCRnet Conference (2023). Her collaborations span institutions in Germany, Australia, and Poland, reflecting global networks in GPCR research. Labs & Teams: Works in the labs of Prof. Denise Wootten and Prof. Patrick Sexton at Monash, focusing on metabolic receptor pharmacology. Her lab employs advanced microscopy and CRISPR tools to study receptor dynamics in live cells.

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Andrew J. Spenceمشاهده پروفایل

دانشیار

Temple UniversityUnited States

Andrew J. Spence is an Associate Professor in the Department of Bioengineering at Temple University's College of Engineering, where he leads the Spence Lab focused on locomotor neuromechanics and spinal cord injury. His work integrates experimental biology, mathematical modeling, robotics, and molecular genetic tools to understand how animals move and how movement can be restored after injury. PhD in Applied and Engineering Physics, Cornell University Postdoctoral training at UC Berkeley with Bob Full and Eileen Hebets Former RCUK Fellow and faculty at the Royal Veterinary College, London Joined Temple University in 2013 His research interests center on the control of locomotion, gait analysis, spinal cord injury, neuroprosthetics, and the application of optogenetics and chemogenetics (DREADDs) in neuromuscular disorders. He also explores biomechanics in diverse species, from insects to racehorses, seeking general principles of movement. The 15 most recent publications reveal a strong trend toward integrating genetic tools with biomechanical analysis, particularly in rodent models of spinal cord injury. His work spans fundamental questions in animal locomotion and applied research in rehabilitation, with increasing emphasis on closed-loop systems, automated tracking, and neuromodulation. RCUK Tenure Track Research Fellowship W.M. Keck Foundation predoctoral fellowship Spence advises a multidisciplinary team of students and postdocs, collaborates with Professors Michel Lemay and George Smith on spinal cord injury projects, and leads NIH-funded research. His lab develops open-source tools for locomotion analysis and has contributed significantly to understanding stability, gait transitions, and sensory feedback in movement. He teaches courses in neuroengineering and biomechanics at both undergraduate and graduate levels. The Spence Lab is actively involved in developing neurogenetic interventions for spinal cord injury, studying gait adaptation in complex environments, and creating innovative instrumentation for neuromechanical research.

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Benoit Labontéمشاهده پروفایل

دانشیار

Laval UniversityCanada

Molecular Neurobiology of Mood Disorders
Sex Differences in Depression
Molecular Mechanisms of Stress Responses
+۴ مورد دیگر

Benoit Labonté is an Associate Professor in the Department of Psychiatry and Neuroscience at the Faculty of Medicine, Université Laval. He holds the Research Chair in partnership with Sentinel North for Molecular Neurobiology of Mood Disorders and is a researcher at the CERVO Brain Research Centre. Previously, he was a Pfizer–Institut universitaire en santé mentale de Québec research chair (2016-2021). Dr. Labonté's research focuses on understanding the molecular basis of depression and mood disorders with a specific emphasis on sex differences. His groundbreaking work has demonstrated that depression manifests differently at the molecular level in men and women, challenging the notion of depression as a single disease. He employs multidisciplinary approaches including: Mouse models of stress (chronic variable stress, chronic social defeat, social isolation) Analysis of human post-mortem brain and blood samples Viral approaches for neural circuit mapping (optogenetics, DREADDs) Genome-wide sequencing methods (RNAseq, ChIPseq) Cell-specific molecular analyses (FACS, ribotag) His research has three primary objectives: Determining the prefrontal cortex (PFC) connectome and evaluating sex-specific neuronal contributions to stress responses Characterizing transcriptional organization of gene networks across neuronal populations projecting to the PFC Identifying epigenetic signatures associated with transcriptional reorganization following chronic stress Dr. Labonté's publication record shows consistent high-impact research across neuroscience disciplines, with recent publications demonstrating sophisticated integration of molecular, cellular, and behavioral approaches to understand sex differences in depression. His work bridges basic science with clinical applications, aiming to develop more targeted therapeutic approaches. His research has been recognized with prestigious appointments including: Sentinel North Partnership Research Chair in Molecular Neurobiology of Mood Disorders (2019-present) Pfizer–Institut universitaire en santé mentale de Québec research chair (2016-2021) Dr. Labonté leads a research team at the CERVO Brain Research Centre focusing on molecular neurobiology of mood disorders. His laboratory employs cutting-edge techniques to investigate sex-specific molecular mechanisms underlying depression, with the ultimate goal of developing more effective treatments that account for fundamental biological differences between men and women suffering from mood disorders.

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Sophie Bradleyمشاهده پروفایل

مدرس ارشد

University of GlasgowUnited Kingdom

Dr. Sophie Bradley is an Honorary Senior Research Fellow and Senior Lecturer in Molecular Pharmacology at the Institute of Molecular, Cell and Systems Biology, University of Glasgow . She is also affiliated with the Centre for Translational Pharmacology and actively participates in the Scottish Dementia Research Consortium and British Pharmacological Society . Education: BSc (Hons. 1st class) in Cell Physiology and Pharmacology, University of Leicester PhD in Cell Physiology and Pharmacology, University of Leicester (BBSRC-CASE with GlaxoSmithKline) Lord Kelvin Adam Smith Fellow, University of Glasgow (2016-2020) Her research centers on G protein-coupled receptors (GPCRs) , particularly their therapeutic potential in neurodegenerative diseases like Alzheimer’s and prion disease. Key areas include M1 muscarinic acetylcholine receptors , metabotropic glutamate receptors , neuroinflammatory modulation , and biased ligand development . Recent publications highlight her work on GPCR signaling pathways , chemogenetic tools , and transgenic mouse models for neurodegeneration. Her team collaborates with academic and industry partners, including Eli Lilly and Sosei-Heptares . Scientific Awards: Gordon Research Conferences Travel Grant Animal Welfare and Ethical Review Board 3R’s Prize Oral Communication Prize, Focused Meeting on Cell Signalling MRC Career Development Fellowship College of Medicine PhD Prize BPS Bain Memorial Fund Bursary She supervises multiple PhD students and secures funding from organizations like Medical Research Scotland and Alzheimer’s Research UK . Her lab employs multi-omics approaches , neuroimaging , and behavioral assays to study receptor pharmacology in disease contexts.

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Remi Martin-Fardonمشاهده پروفایل

دانشیار

Irell and Manella Graduate School of Biological SciencesUnited States

Remi Martin-Fardon is an Associate Professor of Translational Medicine at The Scripps Research Institute (TSRI), located in La Jolla, CA. He holds joint appointments in the Neuroscience department and the Skaggs Graduate School of Chemical and Biological Sciences. His primary research focuses on identifying neurobiological mechanisms underlying drug addiction relapse, particularly examining the role of the hypocretin (orexin) system in compulsive drug-seeking behaviors. Key areas of investigation include comparing neural substrates for drug vs. natural rewards, with emphasis on stress- and cue-induced relapse paradigms using rodent models. Joined TSRI in 1997 as a Postdoctoral Fellow, progressing through roles as Research Associate (2002), Staff Scientist (2004), and achieving Associate Professor status in 2019 Member of the Pearson Center for Alcoholism and Addiction Research since 2017 Research employs advanced techniques including AAV-mediated gene delivery and DREADDs to study brain regions like the paraventricular nucleus of the thalamus (PVT) and central amygdala. Major contributions include linking hypocretin transmission in the PVT to drug-seeking behavior and establishing this brain region's role in addiction circuits. His work also explores sex differences in alcohol dependence treatment responses and the therapeutic potential of orexin receptor antagonists. Over 50 peer-reviewed publications since 2000, with recent focus on opioid use disorder and translational pharmacotherapies Recipient of prestigious awards including the Simone et Cino Del Duca Foundation Award (2000) and NIH travel grants

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Nathan S. Pentkowskiمشاهده پروفایل

دانشیار

University of New MexicoUnited States

Nathan S. Pentkowski is an Associate Professor in the Department of Psychology at the University of New Mexico . His research focuses on the neurobiological mechanisms underlying drug addiction, anxiety disorders, and Alzheimer’s disease, with an emphasis on stress systems and receptor modulation. Key research areas: Neurobiology of drug addiction (cocaine, alcohol, nicotine), social influences on relapse, serotonin receptors, microRNA changes in stress Techniques: Behavioral assays, pharmacology, biochemical imaging, genetic manipulation (DREADD, viral-mediated gene transfer) Selected findings relate to 5-HT1B/2C receptor dynamics , CRF1 stress systems , and miR-495 regulation in addiction and neurodegeneration. Dr. Pentkowski has mentored graduate students including Jack Madden, Carlos Maestas-Olguin, and Kyle Dixon. He teaches courses on Drugs and Behavior , Neurobiology of Addiction , and Molecular Psychiatry . Not accepting students for Fall 2026.

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Brett DiBenedictisمشاهده پروفایل

مدرس ارشد

Boston UniversityUnited States

Brett DiBenedictis is a Senior Lecturer at Boston University, affiliated with the Department of Psychological & Brain Sciences within the College of Arts & Sciences. His office is located at 64 Cummington Mall, Room 135. He holds a Ph.D. from Boston University. Dr. DiBenedictis' research focuses on the neurobiology of social behavior, particularly the role of neuropeptides oxytocin and vasopressin in regulating neural pathways of innate social behavior in mice. His work employs advanced techniques such as chemogenetics, viral tract tracing, and calcium imaging. He also explores undergraduate science education, emphasizing active learning strategies and curriculum innovation. His research spans topics including sex differences in social behavior modulation, neural circuit organization in olfactory systems, and microbial effects on neuroendocrine signaling. While his articles highlight contributions to neuroendocrinology and behavioral neuroscience, no scientific awards are listed here. Dr. DiBenedictis teaches courses like PS/NE 333 (Drugs and Behavior), PS 231 (Physiological Psychology), and BI/NE 230 (Behavioral Endocrinology). His work bridges fundamental neuroscience with translational insights into neuropsychiatric disorders.

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Ewan St. John Smithمشاهده پروفایل

استاد

University of CambridgeUnited Kingdom

Professor Ewan St. John Smith is a Professor of Nociception at the University of Cambridge with a joint appointment as Director of the Naked Mole-Rat Initiative . He received his undergraduate training in Pharmacology at the University of Bath (including industry experience at Novartis) and completed his PhD at Cambridge on acid sensing. His postdoctoral work included 6 years at the Max-Delbrück Centre in Berlin (supported by an Alexander von Humboldt Fellowship) and a Max Kade Fellowship at NYU School of Medicine.

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Kerry Resslerمشاهده پروفایل

استاد

Harvard UniversityUnited States

Neuroscience
Psychiatry
Fear Research
+۳ مورد دیگر

Kerry Ressler is a Professor of Psychiatry at Harvard Medical School and serves as Chief Scientific Officer at McLean Hospital. His research focuses on elucidating the neural and molecular mechanisms underlying fear-based psychiatric disorders, particularly post-traumatic stress disorder (PTSD), phobic disorders, and panic disorders. He leads the Ressler Lab, which integrates translational approaches spanning animal models of fear learning with human genetic and clinical studies to identify novel therapeutic targets. Dr. Ressler's research centers on molecular, genetic, epigenetic, and neural circuit mechanisms of fear memory formation and modulation. His lab employs mouse models of fear acquisition, consolidation, and extinction using optogenetics, DREADDs, cell-type-specific transcriptional profiling, and DNA methylation analyses to investigate amygdala-dependent circuits. Human studies focus on identifying genetic traits and neural processes contributing to fear-based disorders, with emphasis on biomarkers like PACAP, cortisol, and inflammatory markers. This work aims to translate mechanistic insights into targeted treatments for trauma-related illnesses. Analysis of Dr. Ressler's recent publications reveals dominant themes in PTSD neurobiology, including sex-specific responses to trauma, neural circuit dynamics using advanced neuroimaging (fMRI, DTI), and genetic/epigenetic mechanisms. His work frequently involves large-scale collaborations (ENIGMA-PGC, AURORA study) examining biomarkers, white matter integrity, and precision psychiatry frameworks. Key subfields include fear extinction mechanisms, childhood adversity impacts, and inflammatory pathways in trauma responses. Dr. Ressler directs the Ressler Lab at McLean Hospital's Oaks Building, utilizing a multidisciplinary approach that combines molecular genetics, viral-vector manipulations, and human clinical research. The lab is embedded within Harvard Medical School's neuroscience ecosystem and contributes to major initiatives including the ENIGMA-PGC PTSD consortium and AURORA observational cohort study, focusing on translating basic science discoveries into clinical applications for trauma survivors.

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Sarah Heilbronnerمشاهده پروفایل

دانشیار

Rice UniversityUnited States

Sarah Heilbronner serves as Associate Professor of Neurosurgery at Baylor College of Medicine and Adjunct Professor of Electrical and Computer Engineering at Rice University. Her research program centers on decoding primate brain connectivity to advance understanding of neural circuitry and develop neuromodulation therapies for neurological disorders. Her academic foundation includes a Psychology undergraduate degree from Harvard University and a Neurobiology PhD from Duke University under Dr. Michael Platt, followed by neuroanatomy training with Dr. Suzanne Haber at the University of Rochester. She established her independent laboratory at the University of Minnesota in 2017 before relocating to Baylor College of Medicine in March 2023. Dr. Heilbronner's research investigates the structural and functional organization of primate brain networks using multimodal approaches including tract-tracing, diffusion MRI, and PS-OCT imaging. Her lab specifically targets mesoscale connectomics to bridge microscopic neuronal properties with macroscopic brain systems, with applications in psychiatric and neurological disorder treatment. Key focus areas include orbitofrontal cortex subdivisions, posterior cingulate circuitry, and translational mapping of cross-species neural networks. Analysis of her recent publications reveals a cohesive trajectory in primate connectomics methodology development, with increasing emphasis on clinical translation. Her work integrates ultra-high-field imaging (10.5T MRI), chemogenetic circuit manipulation (DREADDs-fMRI), and computational modeling to create comprehensive brain wiring diagrams. Significant collaborative efforts address conservation applications (oxytocin in felids) and surgical neuromodulation targets through population-averaged tractography. Dr. Heilbronner actively mentors trainees across career stages, having guided multiple PhD graduates including Adriana Cushnie (addiction neuroscience), Jessica Burkhart (lion behavior), and Zhe (Maya) Wang (orbitofrontal cortex). Her lab participates in major initiatives including the BRAIN CONNECTS consortium (UM1 grant) and the Center for Mesoscale Connectomics, with collaborations spanning 20+ institutions and clinical departments. The Heilbronner Lab operates from the Bioscience Research Collaborative at Baylor College of Medicine, maintaining strong ties with Rice University's engineering programs. The team employs specialized techniques like PS-OCT and ultra-high-field MRI while contributing to large-scale projects such as the BRAIN Initiative's circuit-mapping goals. Current efforts focus on translating mesoscale connectivity data into clinical applications for brain disorders through partnerships with neurosurgeons and psychiatrists.

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Joanna Elsonمشاهده پروفایل

مدرس

Newcastle UniversityUnited Kingdom

Dr Joanna Elson is a Lecturer at Newcastle University with extensive research expertise in mitochondrial DNA and its role in neurodegenerative diseases. Her work spans over two decades with continuous publication output through 2025, demonstrating sustained research activity and leadership in the field of mitochondrial genetics. She collaborates extensively with leading researchers including Professor Robert Taylor, Emeritus Professor Doug Turnbull, and Dr Ilse Pienaar, primarily through Newcastle University's neuroscience and mitochondrial research groups. Dr Elson's research interests focus on mitochondrial DNA variation and its implications for human health and disease. Her work explores the role of mitochondrial mutations in Parkinson's disease, Alzheimer's disease, chronic fatigue syndrome/ME, and other neurodegenerative conditions. She has developed and applied innovative methodologies including single-cell analysis of mitochondrial DNA, comparative genomics approaches to understanding mutation pathogenicity, and novel models for studying mitochondrial dysfunction in disease contexts. Her research bridges basic molecular mechanisms with clinical applications, particularly in understanding how mitochondrial variation influences disease susceptibility and progression. Analysis of Dr Elson's recent publications reveals a consistent focus on mitochondrial DNA in neurodegenerative disorders, with particular emphasis on Parkinson's disease mechanisms, mitochondrial haplogroup effects across diverse populations, and innovative therapeutic approaches targeting mitochondrial dysfunction. Her work demonstrates sophisticated integration of genetic, molecular, and clinical approaches to unravel the complex relationship between mitochondrial variation and human disease. Dr Elson has made significant contributions to understanding mitochondrial DNA variation across global populations, particularly examining African mitochondrial genome haplogroups and their implications for disease. Her work on mitochondrial mutations in Parkinson's disease has helped clarify the complex relationship between mitochondrial genetics and neurodegenerative processes. She has also contributed to developing new analytical frameworks like Heterologous Inferential Analysis for evaluating mitochondrial mutation pathogenicity. Her research program involves extensive collaboration with clinical and basic science researchers across multiple institutions, focusing on mitochondrial mechanisms in neurodegenerative diseases, chronic fatigue syndrome, and cancer biology. Dr Elson's work has established important connections between mitochondrial genetics and clinical manifestations across multiple disease contexts, advancing our understanding of how mitochondrial variation contributes to human disease susceptibility and progression.

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Jennifer Dulinمشاهده پروفایل

دانشیار

Texas A&M UniversityUnited States

Jennifer Dulin is an Associate Professor at Texas A&M University, specializing in spinal cord injury research. Her lab focuses on developing neural stem/progenitor cell transplantation strategies to restore motor, sensory, and autonomic functions post-injury. She joined Texas A&M in 2017 after completing a PhD in Neuroscience at the University of Texas Health Science Center at Houston and postdoctoral training at UC San Diego. Her work emphasizes scientific rigor, collaboration, and translational approaches toward clinical therapies. Education: BS in Biochemistry (Texas A&M University, 2005); PhD in Neuroscience (University of Texas Health Science Center at Houston, 2012); Postdoctoral Research in Neurosciences (UC San Diego, 2012–2017). Research Interests: Spinal cord injury pathophysiology, neural stem cell transplantation, axon regeneration, hydrogel-based delivery systems, and chemogenetic modulation of pain pathways. Her lab integrates biomaterials, molecular biology, and behavioral analysis to advance therapeutic strategies. Publications highlight federal funding trends, synaptic connectivity restoration, and G3BP1 granule disruption for axon regeneration. Her team’s work on hydrogel scaffolds and combinatorial therapies underscores innovative approaches to neural repair. Labs/Teams: Dulin Lab (Interdisciplinary Life Sciences Building, Texas A&M), collaborating with institutions on spinal cord injury research and clinical translation.

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